TY - JOUR
T1 - Acral melanocytic lesions in the United States
T2 - Prevalence, awareness, and dermoscopic patterns in skin-of-color and non-Hispanic white patients
AU - Madankumar, Reshmi
AU - Gumaste, Priyanka V.
AU - Martires, Kathryn
AU - Schaffer, Panta R.
AU - Choudhary, Sonal
AU - Falto-Aizpurua, Leyre
AU - Arora, Harleen
AU - Kallis, Penelope J.
AU - Patel, Shailee
AU - Damanpour, Shadi
AU - Sanchez, Margaret I.
AU - Yin, Natalie
AU - Chan, Aegean
AU - Sanchez, Miguel
AU - Polsky, David
AU - Kanavy, Holly
AU - Grichnik, James M.
AU - Stein, Jennifer A.
N1 - Publisher Copyright:
© 2015 American Academy of Dermatology, Inc.
PY - 2016/4/1
Y1 - 2016/4/1
N2 - Background Acral lentiginous melanoma has increased mortality compared with other melanoma subtypes and disproportionately affects ethnic minorities. Acral melanocytic lesions have not been well studied in diverse populations of the United States. Objective We sought to assess the prevalence, awareness, and dermoscopic patterns of acral melanocytic lesions in skin-of-color and non-Hispanic white patients. Methods We prospectively examined the palms and soles of 1052 patients presenting to dermatology clinics in New York, NY, and Miami, FL, from October 2013 to April 2015. Results Acral melanocytic lesions were observed in 36% of our cohort. Skin-of-color patients were more likely to have acral melanocytic lesions than non-Hispanic white patients (P <.01). Acral melanocytic lesions correlated with increased mole counts, particularly on non-Hispanic white patients. The majority of lesions demonstrated benign dermoscopic patterns. We observed 2 lesions with the parallel ridge pattern in our cohort, both found to be atypical nevi on biopsy specimen. Patients often lacked awareness of the presence of their lesions. Limitations Interobserver variability in assessing dermoscopic patterns is a limitation. Conclusions Melanocytic lesions of the palms and soles are common, particularly in a cohort of multiple ethnicities from the United States. Dermoscopy of acral lesions is an important clinical tool for diagnosis and management of these lesions.
AB - Background Acral lentiginous melanoma has increased mortality compared with other melanoma subtypes and disproportionately affects ethnic minorities. Acral melanocytic lesions have not been well studied in diverse populations of the United States. Objective We sought to assess the prevalence, awareness, and dermoscopic patterns of acral melanocytic lesions in skin-of-color and non-Hispanic white patients. Methods We prospectively examined the palms and soles of 1052 patients presenting to dermatology clinics in New York, NY, and Miami, FL, from October 2013 to April 2015. Results Acral melanocytic lesions were observed in 36% of our cohort. Skin-of-color patients were more likely to have acral melanocytic lesions than non-Hispanic white patients (P <.01). Acral melanocytic lesions correlated with increased mole counts, particularly on non-Hispanic white patients. The majority of lesions demonstrated benign dermoscopic patterns. We observed 2 lesions with the parallel ridge pattern in our cohort, both found to be atypical nevi on biopsy specimen. Patients often lacked awareness of the presence of their lesions. Limitations Interobserver variability in assessing dermoscopic patterns is a limitation. Conclusions Melanocytic lesions of the palms and soles are common, particularly in a cohort of multiple ethnicities from the United States. Dermoscopy of acral lesions is an important clinical tool for diagnosis and management of these lesions.
KW - acquired acral nevi
KW - acral lentiginous melanoma
KW - acral melanocytic lesions
KW - acral pigmented lesions
KW - dermoscopy
KW - skin of color
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U2 - 10.1016/j.jaad.2015.11.035
DO - 10.1016/j.jaad.2015.11.035
M3 - Article
C2 - 26803347
AN - SCOPUS:84960368302
SN - 0190-9622
VL - 74
SP - 724-730.e1
JO - Journal of the American Academy of Dermatology
JF - Journal of the American Academy of Dermatology
IS - 4
ER -