Abstract
Objectives: The aim of the study was to evaluate the prevalence of and factors associated with abnormal thyroid function in older men with or at risk for HIV infection. Methods: A cross-sectional analysis of 636 men ≥49 years old was carried out using data obtained from interviews, from measurements of body mass index (BMI), HIV-1 serology and viral load, CD4 cell count, hepatitis C virus (HCV) assays, thyroid-stimulating hormone (TSH) and free thyroid hormone levels. Results: Participants were 54% black, 57% overweight/obese, 57% HIV seropositive, and 72% HCV seropositive; 38% reported recent cocaine or heroin use. Decreased TSH was found in 56 men (8.8%) and raised TSH in 23 men (3.6%). Only three men had abnormal free thyroxine levels. Conclusions: Abnormal TSH levels were noted in 12.4% of older men with or at risk for HIV infection, but nearly all reflected subclinical hyperthyroidism or subclinical hypothyroidism.
Original language | English (US) |
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Pages (from-to) | 544-549 |
Number of pages | 6 |
Journal | HIV Medicine |
Volume | 9 |
Issue number | 7 |
DOIs | |
State | Published - 2008 |
Keywords
- Endocrine
- Epidemiology
- Thyroid function tests
- Thyroid hormones
- Thyroid-stimulating hormone
ASJC Scopus subject areas
- Health Policy
- Infectious Diseases
- Pharmacology (medical)