Ablation Versus Amiodarone for Treatment of Persistent Atrial Fibrillation in Patients With Congestive Heart Failure and an Implanted Device

Results From the AATAC Multicenter Randomized Trial

Luigi Di Biase, Prasant Mohanty, Sanghamitra Mohanty, Pasquale Santangeli, Chintan Trivedi, Dhanunjaya Lakkireddy, Madhu Reddy, Pierre Jais, Sakis Themistoclakis, Antonio Dello Russo, Michela Casella, Gemma Pelargonio, Maria Lucia Narducci, Robert Schweikert, Petr Neuzil, Javier Sanchez, Rodney Horton, Salwa Beheiry, Richard Hongo, Steven Hao & 6 others Antonio Rossillo, Giovanni Forleo, Claudio Tondo, J. David Burkhardt, Michel Haissaguerre, Andrea Natale

Research output: Contribution to journalArticle

185 Citations (Scopus)

Abstract

Background - Whether catheter ablation (CA) is superior to amiodarone (AMIO) for the treatment of persistent atrial fibrillation (AF) in patients with heart failure is unknown. Methods and Results - This was an open-label, randomized, parallel-group, multicenter study. Patients with persistent AF, dual-chamber implantable cardioverter defibrillator or cardiac resynchronization therapy defibrillator, New York Heart Association II to III, and left ventricular ejection fraction

Original languageEnglish (US)
Pages (from-to)1637-1644
Number of pages8
JournalCirculation
Volume133
Issue number17
DOIs
StatePublished - Apr 26 2016

Fingerprint

Amiodarone
Atrial Fibrillation
Multicenter Studies
Heart Failure
Equipment and Supplies
Cardiac Resynchronization Therapy
Defibrillators
Catheter Ablation
Implantable Defibrillators
Stroke Volume
Therapeutics

Keywords

  • amiodarone
  • atrial fibrillation
  • catheter ablation
  • heart failure

ASJC Scopus subject areas

  • Physiology (medical)
  • Cardiology and Cardiovascular Medicine

Cite this

Ablation Versus Amiodarone for Treatment of Persistent Atrial Fibrillation in Patients With Congestive Heart Failure and an Implanted Device : Results From the AATAC Multicenter Randomized Trial. / Di Biase, Luigi; Mohanty, Prasant; Mohanty, Sanghamitra; Santangeli, Pasquale; Trivedi, Chintan; Lakkireddy, Dhanunjaya; Reddy, Madhu; Jais, Pierre; Themistoclakis, Sakis; Dello Russo, Antonio; Casella, Michela; Pelargonio, Gemma; Narducci, Maria Lucia; Schweikert, Robert; Neuzil, Petr; Sanchez, Javier; Horton, Rodney; Beheiry, Salwa; Hongo, Richard; Hao, Steven; Rossillo, Antonio; Forleo, Giovanni; Tondo, Claudio; Burkhardt, J. David; Haissaguerre, Michel; Natale, Andrea.

In: Circulation, Vol. 133, No. 17, 26.04.2016, p. 1637-1644.

Research output: Contribution to journalArticle

Di Biase, L, Mohanty, P, Mohanty, S, Santangeli, P, Trivedi, C, Lakkireddy, D, Reddy, M, Jais, P, Themistoclakis, S, Dello Russo, A, Casella, M, Pelargonio, G, Narducci, ML, Schweikert, R, Neuzil, P, Sanchez, J, Horton, R, Beheiry, S, Hongo, R, Hao, S, Rossillo, A, Forleo, G, Tondo, C, Burkhardt, JD, Haissaguerre, M & Natale, A 2016, 'Ablation Versus Amiodarone for Treatment of Persistent Atrial Fibrillation in Patients With Congestive Heart Failure and an Implanted Device: Results From the AATAC Multicenter Randomized Trial', Circulation, vol. 133, no. 17, pp. 1637-1644. https://doi.org/10.1161/CIRCULATIONAHA.115.019406
Di Biase, Luigi ; Mohanty, Prasant ; Mohanty, Sanghamitra ; Santangeli, Pasquale ; Trivedi, Chintan ; Lakkireddy, Dhanunjaya ; Reddy, Madhu ; Jais, Pierre ; Themistoclakis, Sakis ; Dello Russo, Antonio ; Casella, Michela ; Pelargonio, Gemma ; Narducci, Maria Lucia ; Schweikert, Robert ; Neuzil, Petr ; Sanchez, Javier ; Horton, Rodney ; Beheiry, Salwa ; Hongo, Richard ; Hao, Steven ; Rossillo, Antonio ; Forleo, Giovanni ; Tondo, Claudio ; Burkhardt, J. David ; Haissaguerre, Michel ; Natale, Andrea. / Ablation Versus Amiodarone for Treatment of Persistent Atrial Fibrillation in Patients With Congestive Heart Failure and an Implanted Device : Results From the AATAC Multicenter Randomized Trial. In: Circulation. 2016 ; Vol. 133, No. 17. pp. 1637-1644.
@article{0a1673dec52d44289b35ead8c9ce1ae2,
title = "Ablation Versus Amiodarone for Treatment of Persistent Atrial Fibrillation in Patients With Congestive Heart Failure and an Implanted Device: Results From the AATAC Multicenter Randomized Trial",
abstract = "Background - Whether catheter ablation (CA) is superior to amiodarone (AMIO) for the treatment of persistent atrial fibrillation (AF) in patients with heart failure is unknown. Methods and Results - This was an open-label, randomized, parallel-group, multicenter study. Patients with persistent AF, dual-chamber implantable cardioverter defibrillator or cardiac resynchronization therapy defibrillator, New York Heart Association II to III, and left ventricular ejection fraction",
keywords = "amiodarone, atrial fibrillation, catheter ablation, heart failure",
author = "{Di Biase}, Luigi and Prasant Mohanty and Sanghamitra Mohanty and Pasquale Santangeli and Chintan Trivedi and Dhanunjaya Lakkireddy and Madhu Reddy and Pierre Jais and Sakis Themistoclakis and {Dello Russo}, Antonio and Michela Casella and Gemma Pelargonio and Narducci, {Maria Lucia} and Robert Schweikert and Petr Neuzil and Javier Sanchez and Rodney Horton and Salwa Beheiry and Richard Hongo and Steven Hao and Antonio Rossillo and Giovanni Forleo and Claudio Tondo and Burkhardt, {J. David} and Michel Haissaguerre and Andrea Natale",
year = "2016",
month = "4",
day = "26",
doi = "10.1161/CIRCULATIONAHA.115.019406",
language = "English (US)",
volume = "133",
pages = "1637--1644",
journal = "Circulation",
issn = "0009-7322",
publisher = "Lippincott Williams and Wilkins",
number = "17",

}

TY - JOUR

T1 - Ablation Versus Amiodarone for Treatment of Persistent Atrial Fibrillation in Patients With Congestive Heart Failure and an Implanted Device

T2 - Results From the AATAC Multicenter Randomized Trial

AU - Di Biase, Luigi

AU - Mohanty, Prasant

AU - Mohanty, Sanghamitra

AU - Santangeli, Pasquale

AU - Trivedi, Chintan

AU - Lakkireddy, Dhanunjaya

AU - Reddy, Madhu

AU - Jais, Pierre

AU - Themistoclakis, Sakis

AU - Dello Russo, Antonio

AU - Casella, Michela

AU - Pelargonio, Gemma

AU - Narducci, Maria Lucia

AU - Schweikert, Robert

AU - Neuzil, Petr

AU - Sanchez, Javier

AU - Horton, Rodney

AU - Beheiry, Salwa

AU - Hongo, Richard

AU - Hao, Steven

AU - Rossillo, Antonio

AU - Forleo, Giovanni

AU - Tondo, Claudio

AU - Burkhardt, J. David

AU - Haissaguerre, Michel

AU - Natale, Andrea

PY - 2016/4/26

Y1 - 2016/4/26

N2 - Background - Whether catheter ablation (CA) is superior to amiodarone (AMIO) for the treatment of persistent atrial fibrillation (AF) in patients with heart failure is unknown. Methods and Results - This was an open-label, randomized, parallel-group, multicenter study. Patients with persistent AF, dual-chamber implantable cardioverter defibrillator or cardiac resynchronization therapy defibrillator, New York Heart Association II to III, and left ventricular ejection fraction

AB - Background - Whether catheter ablation (CA) is superior to amiodarone (AMIO) for the treatment of persistent atrial fibrillation (AF) in patients with heart failure is unknown. Methods and Results - This was an open-label, randomized, parallel-group, multicenter study. Patients with persistent AF, dual-chamber implantable cardioverter defibrillator or cardiac resynchronization therapy defibrillator, New York Heart Association II to III, and left ventricular ejection fraction

KW - amiodarone

KW - atrial fibrillation

KW - catheter ablation

KW - heart failure

UR - http://www.scopus.com/inward/record.url?scp=84962124333&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84962124333&partnerID=8YFLogxK

U2 - 10.1161/CIRCULATIONAHA.115.019406

DO - 10.1161/CIRCULATIONAHA.115.019406

M3 - Article

VL - 133

SP - 1637

EP - 1644

JO - Circulation

JF - Circulation

SN - 0009-7322

IS - 17

ER -