A Y-chromosomal DNA fragment is conserved in human and chimpanzee

B. K.A. Rasheed, E. C. Whisenant, R. Fernandez, H. Ostrer, Y. M. Bhatnagar

Research output: Contribution to journalArticle

7 Scopus citations

Abstract

A human male-specific Y-chromosomal DNA fragment (λYH2D6) has been isolated. By deletion-mapping analysis, 2D6 has been localized to the euchromatic portion of the long arm (Yq11) of the human Y chromosome. Among great apes, this fragment was found to be conserved in male chimpanzee but was lacking in male gorilla and male orangutan. No homologous fragments were detected in females of orangutan, gorilla, chimpanzee, or human. Nucleotide sequence analysis indicated the presence of partial-Alu-elements and of sequences similar to the GATA repeats of the snake Bkm sequence.

Original languageEnglish (US)
Pages (from-to)416-432
Number of pages17
JournalMolecular Biology and Evolution
Volume8
Issue number4
StatePublished - Jul 10 1991
Externally publishedYes

Keywords

  • DNA
  • Pan
  • Y chromosome
  • evolution
  • human

ASJC Scopus subject areas

  • Ecology, Evolution, Behavior and Systematics
  • Molecular Biology
  • Genetics

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    Rasheed, B. K. A., Whisenant, E. C., Fernandez, R., Ostrer, H., & Bhatnagar, Y. M. (1991). A Y-chromosomal DNA fragment is conserved in human and chimpanzee. Molecular Biology and Evolution, 8(4), 416-432.