A Y-chromosomal DNA fragment is conserved in human and chimpanzee

B. K A Rasheed, E. C. Whisenant, R. Fernandez, H. Ostrer, Y. M. Bhatnagar

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

A human male-specific Y-chromosomal DNA fragment (λYH2D6) has been isolated. By deletion-mapping analysis, 2D6 has been localized to the euchromatic portion of the long arm (Yq11) of the human Y chromosome. Among great apes, this fragment was found to be conserved in male chimpanzee but was lacking in male gorilla and male orangutan. No homologous fragments were detected in females of orangutan, gorilla, chimpanzee, or human. Nucleotide sequence analysis indicated the presence of partial-Alu-elements and of sequences similar to the GATA repeats of the snake Bkm sequence.

Original languageEnglish (US)
Pages (from-to)416-432
Number of pages17
JournalMolecular Biology and Evolution
Volume8
Issue number4
StatePublished - Jul 1991
Externally publishedYes

Fingerprint

Alu Elements
Pan troglodytes
Chromosomes
Nucleotides
Pongo
Gorilla gorilla
DNA
Pongo pygmaeus
Gorilla
Chromosomes, Human, Y
Snakes
Hominidae
Y chromosome
Pongidae
snake
snakes
chromosome mapping
Sequence Analysis
chromosome
sequence analysis

Keywords

  • DNA
  • Evolution
  • Human
  • Pan
  • Y chromosome

ASJC Scopus subject areas

  • Agricultural and Biological Sciences (miscellaneous)
  • Ecology, Evolution, Behavior and Systematics
  • Biochemistry, Genetics and Molecular Biology(all)
  • Biochemistry
  • Genetics
  • Molecular Biology
  • Genetics(clinical)

Cite this

Rasheed, B. K. A., Whisenant, E. C., Fernandez, R., Ostrer, H., & Bhatnagar, Y. M. (1991). A Y-chromosomal DNA fragment is conserved in human and chimpanzee. Molecular Biology and Evolution, 8(4), 416-432.

A Y-chromosomal DNA fragment is conserved in human and chimpanzee. / Rasheed, B. K A; Whisenant, E. C.; Fernandez, R.; Ostrer, H.; Bhatnagar, Y. M.

In: Molecular Biology and Evolution, Vol. 8, No. 4, 07.1991, p. 416-432.

Research output: Contribution to journalArticle

Rasheed, BKA, Whisenant, EC, Fernandez, R, Ostrer, H & Bhatnagar, YM 1991, 'A Y-chromosomal DNA fragment is conserved in human and chimpanzee', Molecular Biology and Evolution, vol. 8, no. 4, pp. 416-432.
Rasheed BKA, Whisenant EC, Fernandez R, Ostrer H, Bhatnagar YM. A Y-chromosomal DNA fragment is conserved in human and chimpanzee. Molecular Biology and Evolution. 1991 Jul;8(4):416-432.
Rasheed, B. K A ; Whisenant, E. C. ; Fernandez, R. ; Ostrer, H. ; Bhatnagar, Y. M. / A Y-chromosomal DNA fragment is conserved in human and chimpanzee. In: Molecular Biology and Evolution. 1991 ; Vol. 8, No. 4. pp. 416-432.
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