Abstract
A human male-specific Y-chromosomal DNA fragment (λYH2D6) has been isolated. By deletion-mapping analysis, 2D6 has been localized to the euchromatic portion of the long arm (Yq11) of the human Y chromosome. Among great apes, this fragment was found to be conserved in male chimpanzee but was lacking in male gorilla and male orangutan. No homologous fragments were detected in females of orangutan, gorilla, chimpanzee, or human. Nucleotide sequence analysis indicated the presence of partial-Alu-elements and of sequences similar to the GATA repeats of the snake Bkm sequence.
Original language | English (US) |
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Pages (from-to) | 416-432 |
Number of pages | 17 |
Journal | Molecular Biology and Evolution |
Volume | 8 |
Issue number | 4 |
State | Published - Jul 1991 |
Externally published | Yes |
Keywords
- DNA
- Evolution
- Human
- Pan
- Y chromosome
ASJC Scopus subject areas
- Genetics
- Ecology, Evolution, Behavior and Systematics
- Molecular Biology