A triglyceride/high-density lipoprotein ratio > or = 3.5 is associated with an increased burden of coronary artery disease on cardiac catheterization.

Robert J Ostfeld, Disha Mookherjee, Michael Spinelli, Dvorah Holtzman, Abu Shoyeb, Michael Schaefer, Sanjay Doddamani, Daniel M. Spevack, Yunling Du

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

An elevated triglyceride (TG)/high-density lipoprotein (HDL) ratio has been described as a predictor of insulin resistance and cardiovascular events. We evaluated whether a TG/HDL ratio > or = 3.5 was associated with the burden of coronary artery disease (CAD) on cardiac catheterization. A retrospective chart review of 156 consecutive adults presenting to the Montefiore Medical Center Emergency Department with symptoms of unstable angina and no known history of CAD who underwent cardiac catheterization as part of their index hospitalization was performed. TG and HDL data were available in 100 patients within 6 months prior to admission and no more than 24 hours after presentation. A priori, a burden of CAD score was developed. On multivariate analysis, a TG/HDL ratio > or = 3.5 was associated with the burden of CAD (odds ratio, 2.87; 95% confidence interval, 1.03-7.96; p = 0.04). Further study is warranted.

Original languageEnglish (US)
Pages (from-to)13-15
Number of pages3
JournalJournal of the CardioMetabolic Syndrome
Volume1
Issue number1
DOIs
StatePublished - Dec 2006

Fingerprint

HDL Lipoproteins
Cardiac Catheterization
Coronary Artery Disease
Triglycerides
Unstable Angina
Insulin Resistance
Hospital Emergency Service
Hospitalization
Multivariate Analysis
Odds Ratio
Confidence Intervals

ASJC Scopus subject areas

  • Medicine(all)

Cite this

A triglyceride/high-density lipoprotein ratio > or = 3.5 is associated with an increased burden of coronary artery disease on cardiac catheterization. / Ostfeld, Robert J; Mookherjee, Disha; Spinelli, Michael; Holtzman, Dvorah; Shoyeb, Abu; Schaefer, Michael; Doddamani, Sanjay; Spevack, Daniel M.; Du, Yunling.

In: Journal of the CardioMetabolic Syndrome, Vol. 1, No. 1, 12.2006, p. 13-15.

Research output: Contribution to journalArticle

Ostfeld, Robert J ; Mookherjee, Disha ; Spinelli, Michael ; Holtzman, Dvorah ; Shoyeb, Abu ; Schaefer, Michael ; Doddamani, Sanjay ; Spevack, Daniel M. ; Du, Yunling. / A triglyceride/high-density lipoprotein ratio > or = 3.5 is associated with an increased burden of coronary artery disease on cardiac catheterization. In: Journal of the CardioMetabolic Syndrome. 2006 ; Vol. 1, No. 1. pp. 13-15.
@article{f3d213599cdb4bf1aff1ddd5fcbe75f4,
title = "A triglyceride/high-density lipoprotein ratio > or = 3.5 is associated with an increased burden of coronary artery disease on cardiac catheterization.",
abstract = "An elevated triglyceride (TG)/high-density lipoprotein (HDL) ratio has been described as a predictor of insulin resistance and cardiovascular events. We evaluated whether a TG/HDL ratio > or = 3.5 was associated with the burden of coronary artery disease (CAD) on cardiac catheterization. A retrospective chart review of 156 consecutive adults presenting to the Montefiore Medical Center Emergency Department with symptoms of unstable angina and no known history of CAD who underwent cardiac catheterization as part of their index hospitalization was performed. TG and HDL data were available in 100 patients within 6 months prior to admission and no more than 24 hours after presentation. A priori, a burden of CAD score was developed. On multivariate analysis, a TG/HDL ratio > or = 3.5 was associated with the burden of CAD (odds ratio, 2.87; 95{\%} confidence interval, 1.03-7.96; p = 0.04). Further study is warranted.",
author = "Ostfeld, {Robert J} and Disha Mookherjee and Michael Spinelli and Dvorah Holtzman and Abu Shoyeb and Michael Schaefer and Sanjay Doddamani and Spevack, {Daniel M.} and Yunling Du",
year = "2006",
month = "12",
doi = "10.1111/j.0197-3118.2006.05323.x",
language = "English (US)",
volume = "1",
pages = "13--15",
journal = "Journal of the CardioMetabolic Syndrome",
issn = "1559-4564",
publisher = "Le Jacq Ltd.",
number = "1",

}

TY - JOUR

T1 - A triglyceride/high-density lipoprotein ratio > or = 3.5 is associated with an increased burden of coronary artery disease on cardiac catheterization.

AU - Ostfeld, Robert J

AU - Mookherjee, Disha

AU - Spinelli, Michael

AU - Holtzman, Dvorah

AU - Shoyeb, Abu

AU - Schaefer, Michael

AU - Doddamani, Sanjay

AU - Spevack, Daniel M.

AU - Du, Yunling

PY - 2006/12

Y1 - 2006/12

N2 - An elevated triglyceride (TG)/high-density lipoprotein (HDL) ratio has been described as a predictor of insulin resistance and cardiovascular events. We evaluated whether a TG/HDL ratio > or = 3.5 was associated with the burden of coronary artery disease (CAD) on cardiac catheterization. A retrospective chart review of 156 consecutive adults presenting to the Montefiore Medical Center Emergency Department with symptoms of unstable angina and no known history of CAD who underwent cardiac catheterization as part of their index hospitalization was performed. TG and HDL data were available in 100 patients within 6 months prior to admission and no more than 24 hours after presentation. A priori, a burden of CAD score was developed. On multivariate analysis, a TG/HDL ratio > or = 3.5 was associated with the burden of CAD (odds ratio, 2.87; 95% confidence interval, 1.03-7.96; p = 0.04). Further study is warranted.

AB - An elevated triglyceride (TG)/high-density lipoprotein (HDL) ratio has been described as a predictor of insulin resistance and cardiovascular events. We evaluated whether a TG/HDL ratio > or = 3.5 was associated with the burden of coronary artery disease (CAD) on cardiac catheterization. A retrospective chart review of 156 consecutive adults presenting to the Montefiore Medical Center Emergency Department with symptoms of unstable angina and no known history of CAD who underwent cardiac catheterization as part of their index hospitalization was performed. TG and HDL data were available in 100 patients within 6 months prior to admission and no more than 24 hours after presentation. A priori, a burden of CAD score was developed. On multivariate analysis, a TG/HDL ratio > or = 3.5 was associated with the burden of CAD (odds ratio, 2.87; 95% confidence interval, 1.03-7.96; p = 0.04). Further study is warranted.

UR - http://www.scopus.com/inward/record.url?scp=35248886639&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=35248886639&partnerID=8YFLogxK

U2 - 10.1111/j.0197-3118.2006.05323.x

DO - 10.1111/j.0197-3118.2006.05323.x

M3 - Article

C2 - 17675905

AN - SCOPUS:35248886639

VL - 1

SP - 13

EP - 15

JO - Journal of the CardioMetabolic Syndrome

JF - Journal of the CardioMetabolic Syndrome

SN - 1559-4564

IS - 1

ER -