A treatment trial of vitamin d supplementation in breast-fed infants: Universal supplementation is not necessary for rickets preventio in southern louisiana

Tulasi Ponnapakkam, Elease Bradford, Robert Gensure

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

This study was conducted to determine if vitamin D supplementation is required to prevent rickets in breast-fed infants. Breast-feeding rates are increasing, and there are concerns about whether the vitamin D content of breast milk is sufficient. There are a few treatment trials of vitamin D supplementation in breast-fed infants; these were conducted in northern climates. The authors therefore performed a prospective clinical trial comparing vitamin D supplementation with placebo as control in southern Louisiana. Blood samples and questionnaires were collected at birth, 2, 4, and 6 months of age. There were no cases of rickets observed, and no differences in alkaline phosphatas levels between groups. Thus, there was no evidence that vitamin D supplementation reduced rickets risk in theauthors' study population. This suggests that the current recommendations for universal vitamin D supplementationof breast-fed infants throughout the United States may need to be revised.

Original languageEnglish (US)
Pages (from-to)1053-1060
Number of pages8
JournalClinical Pediatrics
Volume49
Issue number11
DOIs
StatePublished - Nov 2010
Externally publishedYes

Fingerprint

Rickets
Vitamin D
Vitamins
Breast
Therapeutics
Human Milk
Breast Feeding
Climate
Placebos
Clinical Trials
Parturition
Population

Keywords

  • American Academy of Pediatrics (AAP)
  • Rickets
  • Vitamin D supplementation

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

Cite this

A treatment trial of vitamin d supplementation in breast-fed infants : Universal supplementation is not necessary for rickets preventio in southern louisiana. / Ponnapakkam, Tulasi; Bradford, Elease; Gensure, Robert.

In: Clinical Pediatrics, Vol. 49, No. 11, 11.2010, p. 1053-1060.

Research output: Contribution to journalArticle

@article{0ba748ae38344319a49cd61f8accdbf7,
title = "A treatment trial of vitamin d supplementation in breast-fed infants: Universal supplementation is not necessary for rickets preventio in southern louisiana",
abstract = "This study was conducted to determine if vitamin D supplementation is required to prevent rickets in breast-fed infants. Breast-feeding rates are increasing, and there are concerns about whether the vitamin D content of breast milk is sufficient. There are a few treatment trials of vitamin D supplementation in breast-fed infants; these were conducted in northern climates. The authors therefore performed a prospective clinical trial comparing vitamin D supplementation with placebo as control in southern Louisiana. Blood samples and questionnaires were collected at birth, 2, 4, and 6 months of age. There were no cases of rickets observed, and no differences in alkaline phosphatas levels between groups. Thus, there was no evidence that vitamin D supplementation reduced rickets risk in theauthors' study population. This suggests that the current recommendations for universal vitamin D supplementationof breast-fed infants throughout the United States may need to be revised.",
keywords = "American Academy of Pediatrics (AAP), Rickets, Vitamin D supplementation",
author = "Tulasi Ponnapakkam and Elease Bradford and Robert Gensure",
year = "2010",
month = "11",
doi = "10.1177/0009922810376320",
language = "English (US)",
volume = "49",
pages = "1053--1060",
journal = "Clinical Pediatrics",
issn = "0009-9228",
publisher = "SAGE Publications Inc.",
number = "11",

}

TY - JOUR

T1 - A treatment trial of vitamin d supplementation in breast-fed infants

T2 - Universal supplementation is not necessary for rickets preventio in southern louisiana

AU - Ponnapakkam, Tulasi

AU - Bradford, Elease

AU - Gensure, Robert

PY - 2010/11

Y1 - 2010/11

N2 - This study was conducted to determine if vitamin D supplementation is required to prevent rickets in breast-fed infants. Breast-feeding rates are increasing, and there are concerns about whether the vitamin D content of breast milk is sufficient. There are a few treatment trials of vitamin D supplementation in breast-fed infants; these were conducted in northern climates. The authors therefore performed a prospective clinical trial comparing vitamin D supplementation with placebo as control in southern Louisiana. Blood samples and questionnaires were collected at birth, 2, 4, and 6 months of age. There were no cases of rickets observed, and no differences in alkaline phosphatas levels between groups. Thus, there was no evidence that vitamin D supplementation reduced rickets risk in theauthors' study population. This suggests that the current recommendations for universal vitamin D supplementationof breast-fed infants throughout the United States may need to be revised.

AB - This study was conducted to determine if vitamin D supplementation is required to prevent rickets in breast-fed infants. Breast-feeding rates are increasing, and there are concerns about whether the vitamin D content of breast milk is sufficient. There are a few treatment trials of vitamin D supplementation in breast-fed infants; these were conducted in northern climates. The authors therefore performed a prospective clinical trial comparing vitamin D supplementation with placebo as control in southern Louisiana. Blood samples and questionnaires were collected at birth, 2, 4, and 6 months of age. There were no cases of rickets observed, and no differences in alkaline phosphatas levels between groups. Thus, there was no evidence that vitamin D supplementation reduced rickets risk in theauthors' study population. This suggests that the current recommendations for universal vitamin D supplementationof breast-fed infants throughout the United States may need to be revised.

KW - American Academy of Pediatrics (AAP)

KW - Rickets

KW - Vitamin D supplementation

UR - http://www.scopus.com/inward/record.url?scp=79952276354&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=79952276354&partnerID=8YFLogxK

U2 - 10.1177/0009922810376320

DO - 10.1177/0009922810376320

M3 - Article

C2 - 20724336

AN - SCOPUS:79952276354

VL - 49

SP - 1053

EP - 1060

JO - Clinical Pediatrics

JF - Clinical Pediatrics

SN - 0009-9228

IS - 11

ER -