A resonance Raman study of the temperature dependence of ligand photolysis and recombination in hemoglobins

M. R. Ondrias, T. W. Scott, J. M. Friedman, V. W. Macdonald

Research output: Contribution to journalArticle

6 Scopus citations


Transient Raman spectroscopy has been used to study geminate recombination in photolyzed hemoglobins at cryogenic temperatures. The temperature dependence of the deoxy heme survival probability during a 10 ns photolysis event is analyzed in terms of a distribution of energy barriers. Studies employing different ligands (CO, O2, NO), and a mutant hemoglobin (hemoglobin Zurich) demonstrates that the barriers controlling rebinding at early times are both and protein specific.

Original languageEnglish (US)
Pages (from-to)351-355
Number of pages5
JournalChemical Physics Letters
Issue number4
Publication statusPublished - Dec 14 1984
Externally publishedYes


ASJC Scopus subject areas

  • Physics and Astronomy(all)
  • Physical and Theoretical Chemistry

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