@article{1d264926eed74ef6b59eb31a0e9474f2,
title = "A research framework for cognitive aging and Alzheimer's disease among diverse US Latinos: Design and implementation of the Hispanic Community Health Study/Study of Latinos—Investigation of Neurocognitive Aging (SOL-INCA)",
abstract = "Hispanics/Latinos are the largest ethnic/racial group in the United States and at high risk for Alzheimer's disease and related dementia (ADRD). Yet, ADRD among diverse Latinos is poorly understood and disparately understudied or unstudied compared to other ethnic/racial groups that leave the nation ill-prepared for major demographic shifts that lay ahead in coming decades. The primary purpose of this Perspectives article was to provide a new research framework for advancing Latino ADRD knowledge, encompassing the unique sociocultural, cardiometabolic, and genomic aspects of Latino health, aging, and ADRD. In addition, we describe some of the research challenges to progress in Latino ADRD research. Finally, we present the Study of Latinos – Investigation of Neurocognitive Aging (SOL-INCA) as an example of implementing this new framework for advancing Latino ADRD research.",
keywords = "Cognitive function, Epidemiology, Hispanic/Latinos, Hispanics, Latinos, Neurocognitive function, Neuroepidemiology, Neuropsychology, Population neuroscience",
author = "Gonz{\'a}lez, {Hector M.} and Wassim Tarraf and Myriam Fornage and Gonz{\'a}lez, {Kevin A.} and Albert Chai and Marston Youngblood and Abreu, {Maria de los Angeles} and Donglin Zeng and Sonia Thomas and Talavera, {Gregory A.} and Gallo, {Linda C.} and Robert Kaplan and Daviglus, {Martha L.} and Neil Schneiderman",
note = "Funding Information: This work was supported by the National Institutes of Health and the National Institute on Aging in particular. Its contents are solely the responsibility of the authors and do not necessarily represent the official views of the NIH. Funding Information: This work is supported by National Institute on Aging ( R01AG048642 , RF1AG054548 , RF1AG061022 , and R21AG056952 ). The Hispanic Community Health Study/Study of Latinos was carried out as a collaborative study supported by contracts from the National Heart, Lung, and Blood Institute (NHLBI) to the University of North Carolina ( N01-HC65233 ), University of Miami ( N01-HC65234 ), Albert Einstein College of Medicine ( N01-HC65235 ), Northwestern University ( N01-HC65236 ), and San Diego State University ( N01-HC65237 ). The following Institutes/Centers/Offices contribute to the HCHS/SOL through a transfer of funds to the NHLBI: National Institute on Minority Health and Health Disparities , National Institute on Deafness and Other Communication Disorders , National Institute of Dental and Craniofacial Research , National Institute of Diabetes and Digestive and Kidney Diseases , National Institute of Neurological Disorders and Stroke , NIH Institution- Office of Dietary Supplements . Funding Information: The authors thank the staff and participants of HCHS/SOL for their important contributions. Investigators web site—http://www.cscc.unc.edu/hchs/. This work is supported by National Institute on Aging (R01AG048642, RF1AG054548, RF1AG061022, and R21AG056952). The Hispanic Community Health Study/Study of Latinos was carried out as a collaborative study supported by contracts from the National Heart, Lung, and Blood Institute (NHLBI) to the University of North Carolina (N01-HC65233), University of Miami (N01-HC65234), Albert Einstein College of Medicine (N01-HC65235), Northwestern University (N01-HC65236), and San Diego State University (N01-HC65237). The following Institutes/Centers/Offices contribute to the HCHS/SOL through a transfer of funds to the NHLBI: National Institute on Minority Health and Health Disparities, National Institute on Deafness and Other Communication Disorders, National Institute of Dental and Craniofacial Research, National Institute of Diabetes and Digestive and Kidney Diseases, National Institute of Neurological Disorders and Stroke, NIH Institution-Office of Dietary Supplements. This work was supported by the National Institutes of Health and the National Institute on Aging in particular. Its contents are solely the responsibility of the authors and do not necessarily represent the official views of the NIH. Publisher Copyright: {\textcopyright} 2019 the Alzheimer's Association",
year = "2019",
month = dec,
doi = "10.1016/j.jalz.2019.08.192",
language = "English (US)",
volume = "15",
pages = "1624--1632",
journal = "Alzheimer's and Dementia",
issn = "1552-5260",
publisher = "Elsevier Inc.",
number = "12",
}