A research framework for cognitive aging and Alzheimer's disease among diverse US Latinos: Design and implementation of the Hispanic Community Health Study/Study of Latinos—Investigation of Neurocognitive Aging (SOL-INCA)

Hector M. González, Wassim Tarraf, Myriam Fornage, Kevin A. González, Albert Chai, Marston Youngblood, Maria de los Angeles Abreu, Donglin Zeng, Sonia Thomas, Gregory A. Talavera, Linda C. Gallo, Robert Kaplan, Martha L. Daviglus, Neil Schneiderman

Research output: Contribution to journalShort survey

Abstract

Hispanics/Latinos are the largest ethnic/racial group in the United States and at high risk for Alzheimer's disease and related dementia (ADRD). Yet, ADRD among diverse Latinos is poorly understood and disparately understudied or unstudied compared to other ethnic/racial groups that leave the nation ill-prepared for major demographic shifts that lay ahead in coming decades. The primary purpose of this Perspectives article was to provide a new research framework for advancing Latino ADRD knowledge, encompassing the unique sociocultural, cardiometabolic, and genomic aspects of Latino health, aging, and ADRD. In addition, we describe some of the research challenges to progress in Latino ADRD research. Finally, we present the Study of Latinos – Investigation of Neurocognitive Aging (SOL-INCA) as an example of implementing this new framework for advancing Latino ADRD research.

Original languageEnglish (US)
Pages (from-to)1624-1632
Number of pages9
JournalAlzheimer's and Dementia
Volume15
Issue number12
DOIs
StatePublished - Dec 2019
Externally publishedYes

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Keywords

  • Cognitive function
  • Epidemiology
  • Hispanic/Latinos
  • Hispanics
  • Latinos
  • Neurocognitive function
  • Neuroepidemiology
  • Neuropsychology
  • Population neuroscience

ASJC Scopus subject areas

  • Epidemiology
  • Health Policy
  • Developmental Neuroscience
  • Clinical Neurology
  • Geriatrics and Gerontology
  • Psychiatry and Mental health
  • Cellular and Molecular Neuroscience

Cite this

González, H. M., Tarraf, W., Fornage, M., González, K. A., Chai, A., Youngblood, M., Abreu, M. D. L. A., Zeng, D., Thomas, S., Talavera, G. A., Gallo, L. C., Kaplan, R., Daviglus, M. L., & Schneiderman, N. (2019). A research framework for cognitive aging and Alzheimer's disease among diverse US Latinos: Design and implementation of the Hispanic Community Health Study/Study of Latinos—Investigation of Neurocognitive Aging (SOL-INCA). Alzheimer's and Dementia, 15(12), 1624-1632. https://doi.org/10.1016/j.jalz.2019.08.192