A pilot program to evaluate deceased donor disease transmission risk: The new york organ donor network infectious disease working group

Rebecca Pellett Madan, Kristin Delli Carpini, Shirish Huprikar, Harvey Lerner, Gopi Patel, Lloyd E. Ratner, Michael J. Goldstein, Betsy Herold

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Background. Recent cases of donor-derived infections raise the question of how best to screen donors without excessive restriction of the donor pool. Methods. The New York Organ Donor Network (NYODN) established an Infectious Diseases Working Group (IDWG) in 2008, which established an on-call schedule of voluntary transplant infectious disease physicians to provide remote evaluations for donors at increased risk for disease transmission. Results. Data were reviewed from 40 available IDWG evaluations from 2008 to 2011. Eighteen cases (45%) were considered to be at unacceptable risk for infection transmission. Sixteen of these cases were excluded from donation secondary to IDWG recommendation; there was limited recipient center interest in the remaining two cases. Approximately 22 (55%) cases were categorized by the IDWG as acceptable, with 14 proceeding to recovery of 49 organs. IDWG physician recommendations were conveyed to recipient centers, and screening guidelines for donors were revised based on the IDWG experiences. Conclusion. Establishment of a donation service area disease transmission evaluation service is a valuable program for donor screening and may promote dissemination of more detailed donor information to recipient centers.

Original languageEnglish (US)
Pages (from-to)909-915
Number of pages7
JournalTransplantation
Volume98
Issue number8
DOIs
StatePublished - 2014

Fingerprint

Communicable Diseases
Tissue Donors
Donor Selection
Physicians
Infectious Disease Transmission
Appointments and Schedules
Guidelines
Transplants
Infection

Keywords

  • Disease transmission
  • Donor evaluation
  • Infectious diseases

ASJC Scopus subject areas

  • Transplantation
  • Medicine(all)

Cite this

A pilot program to evaluate deceased donor disease transmission risk : The new york organ donor network infectious disease working group. / Madan, Rebecca Pellett; Carpini, Kristin Delli; Huprikar, Shirish; Lerner, Harvey; Patel, Gopi; Ratner, Lloyd E.; Goldstein, Michael J.; Herold, Betsy.

In: Transplantation, Vol. 98, No. 8, 2014, p. 909-915.

Research output: Contribution to journalArticle

Madan, Rebecca Pellett ; Carpini, Kristin Delli ; Huprikar, Shirish ; Lerner, Harvey ; Patel, Gopi ; Ratner, Lloyd E. ; Goldstein, Michael J. ; Herold, Betsy. / A pilot program to evaluate deceased donor disease transmission risk : The new york organ donor network infectious disease working group. In: Transplantation. 2014 ; Vol. 98, No. 8. pp. 909-915.
@article{6d75541928994229bbb17d3ad75a5e90,
title = "A pilot program to evaluate deceased donor disease transmission risk: The new york organ donor network infectious disease working group",
abstract = "Background. Recent cases of donor-derived infections raise the question of how best to screen donors without excessive restriction of the donor pool. Methods. The New York Organ Donor Network (NYODN) established an Infectious Diseases Working Group (IDWG) in 2008, which established an on-call schedule of voluntary transplant infectious disease physicians to provide remote evaluations for donors at increased risk for disease transmission. Results. Data were reviewed from 40 available IDWG evaluations from 2008 to 2011. Eighteen cases (45{\%}) were considered to be at unacceptable risk for infection transmission. Sixteen of these cases were excluded from donation secondary to IDWG recommendation; there was limited recipient center interest in the remaining two cases. Approximately 22 (55{\%}) cases were categorized by the IDWG as acceptable, with 14 proceeding to recovery of 49 organs. IDWG physician recommendations were conveyed to recipient centers, and screening guidelines for donors were revised based on the IDWG experiences. Conclusion. Establishment of a donation service area disease transmission evaluation service is a valuable program for donor screening and may promote dissemination of more detailed donor information to recipient centers.",
keywords = "Disease transmission, Donor evaluation, Infectious diseases",
author = "Madan, {Rebecca Pellett} and Carpini, {Kristin Delli} and Shirish Huprikar and Harvey Lerner and Gopi Patel and Ratner, {Lloyd E.} and Goldstein, {Michael J.} and Betsy Herold",
year = "2014",
doi = "10.1097/TP.0000000000000152",
language = "English (US)",
volume = "98",
pages = "909--915",
journal = "Transplantation",
issn = "0041-1337",
publisher = "Lippincott Williams and Wilkins",
number = "8",

}

TY - JOUR

T1 - A pilot program to evaluate deceased donor disease transmission risk

T2 - The new york organ donor network infectious disease working group

AU - Madan, Rebecca Pellett

AU - Carpini, Kristin Delli

AU - Huprikar, Shirish

AU - Lerner, Harvey

AU - Patel, Gopi

AU - Ratner, Lloyd E.

AU - Goldstein, Michael J.

AU - Herold, Betsy

PY - 2014

Y1 - 2014

N2 - Background. Recent cases of donor-derived infections raise the question of how best to screen donors without excessive restriction of the donor pool. Methods. The New York Organ Donor Network (NYODN) established an Infectious Diseases Working Group (IDWG) in 2008, which established an on-call schedule of voluntary transplant infectious disease physicians to provide remote evaluations for donors at increased risk for disease transmission. Results. Data were reviewed from 40 available IDWG evaluations from 2008 to 2011. Eighteen cases (45%) were considered to be at unacceptable risk for infection transmission. Sixteen of these cases were excluded from donation secondary to IDWG recommendation; there was limited recipient center interest in the remaining two cases. Approximately 22 (55%) cases were categorized by the IDWG as acceptable, with 14 proceeding to recovery of 49 organs. IDWG physician recommendations were conveyed to recipient centers, and screening guidelines for donors were revised based on the IDWG experiences. Conclusion. Establishment of a donation service area disease transmission evaluation service is a valuable program for donor screening and may promote dissemination of more detailed donor information to recipient centers.

AB - Background. Recent cases of donor-derived infections raise the question of how best to screen donors without excessive restriction of the donor pool. Methods. The New York Organ Donor Network (NYODN) established an Infectious Diseases Working Group (IDWG) in 2008, which established an on-call schedule of voluntary transplant infectious disease physicians to provide remote evaluations for donors at increased risk for disease transmission. Results. Data were reviewed from 40 available IDWG evaluations from 2008 to 2011. Eighteen cases (45%) were considered to be at unacceptable risk for infection transmission. Sixteen of these cases were excluded from donation secondary to IDWG recommendation; there was limited recipient center interest in the remaining two cases. Approximately 22 (55%) cases were categorized by the IDWG as acceptable, with 14 proceeding to recovery of 49 organs. IDWG physician recommendations were conveyed to recipient centers, and screening guidelines for donors were revised based on the IDWG experiences. Conclusion. Establishment of a donation service area disease transmission evaluation service is a valuable program for donor screening and may promote dissemination of more detailed donor information to recipient centers.

KW - Disease transmission

KW - Donor evaluation

KW - Infectious diseases

UR - http://www.scopus.com/inward/record.url?scp=84922017016&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84922017016&partnerID=8YFLogxK

U2 - 10.1097/TP.0000000000000152

DO - 10.1097/TP.0000000000000152

M3 - Article

C2 - 24879385

AN - SCOPUS:84922017016

VL - 98

SP - 909

EP - 915

JO - Transplantation

JF - Transplantation

SN - 0041-1337

IS - 8

ER -