A pilot follow-up study of childhood soft signs and the development of adult psychopathology

E. Hollander, C. M. DeCaria, B. Aronowitz, D. F. Klein, M. R. Liebowitz, D. Shaffer

Research output: Contribution to journalArticle

25 Scopus citations


A subgroup of subjects (4 of 12) with childhood soft signs and adolescent anxiety-withdrawal disorders were followed up into adulthood and assessed for soft signs and psychiatric diagnoses. These subjects continued to have soft-sign abnormalities and most had adult anxiety or affective disorders, including obsessive-compulsive disorder (OCD). In contrast, control subjects with childhood soft signs but no adolescent anxiety disorders had fewer soft signs at follow-up and no discrete adult anxiety or affective disorders, but they did have obsessive-compulsive symptoms that did not meet criteria for OCD.

Original languageEnglish (US)
Pages (from-to)186-189
Number of pages4
JournalJournal of Neuropsychiatry and Clinical Neurosciences
Issue number2
Publication statusPublished - Jan 1 1991
Externally publishedYes


ASJC Scopus subject areas

  • Clinical Neurology
  • Psychiatry and Mental health

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