A phase II trial of m-AMSA in patients with small-cell lung cancer.

R. B. Natale, R. J. Gralla, R. E. Wittes

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Abstract

Eighteen patients with small-cell lung cancer were treated with m-AMSA in doses of 90 mg/m2 or 120 mg/m2 intravenously every 3 weeks. There were no useful therapeutic responses in the 16 patients receiving adequate trials of the drug. Myelosuppression was the only significant dose-limiting side effect of treatment. m-AMSA in this dose and schedule is not sufficiently active in small-cell lung cancer to warrant further study in a heavily treated patient population.

Original languageEnglish (US)
Pages (from-to)393-395
Number of pages3
JournalCancer clinical trials
Volume4
Issue number4
Publication statusPublished - Dec 1 1981

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ASJC Scopus subject areas

  • Medicine(all)

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Natale, R. B., Gralla, R. J., & Wittes, R. E. (1981). A phase II trial of m-AMSA in patients with small-cell lung cancer. Cancer clinical trials, 4(4), 393-395.