A novel second line chemotherapy treatment of recurrent thymoma

Naveed Jan, Gina M. Villani, Jonathan J. Trambert, Carol Fehmian, Brij Sood, Peter H. Wiernik

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

Thymoma is an uncommon malignancy which is initially treated with surgery. Combined modality treatment with radiation and chemotherapy is utilized in cases of unresectable or metastatic disease. In patients with relapse, a number of different chemotherapeutic regimens have been used with varying success. The case of a male with recurrent thymoma treated with carboplatin and paclitaxel is presented and the literature reviewed. The patient responded to this novel regimen with improvement in clinical symptoms and reduction in tumor mass. This novel regimen has shown activity as second line therapy and merits further investigation as a first line treatment for patients with invasive and or metastatic thymoma.

Original languageEnglish (US)
Pages (from-to)163-168
Number of pages6
JournalMedical Oncology
Volume14
Issue number3-4
StatePublished - Sep 1997

Fingerprint

Thymoma
Drug Therapy
Carboplatin
Paclitaxel
Neoplasms
Therapeutics
Radiation
Recurrence

Keywords

  • Carboplatinum
  • Chemotherapy
  • Paclitaxel
  • Thymoma

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

Cite this

Jan, N., Villani, G. M., Trambert, J. J., Fehmian, C., Sood, B., & Wiernik, P. H. (1997). A novel second line chemotherapy treatment of recurrent thymoma. Medical Oncology, 14(3-4), 163-168.

A novel second line chemotherapy treatment of recurrent thymoma. / Jan, Naveed; Villani, Gina M.; Trambert, Jonathan J.; Fehmian, Carol; Sood, Brij; Wiernik, Peter H.

In: Medical Oncology, Vol. 14, No. 3-4, 09.1997, p. 163-168.

Research output: Contribution to journalArticle

Jan, N, Villani, GM, Trambert, JJ, Fehmian, C, Sood, B & Wiernik, PH 1997, 'A novel second line chemotherapy treatment of recurrent thymoma', Medical Oncology, vol. 14, no. 3-4, pp. 163-168.
Jan N, Villani GM, Trambert JJ, Fehmian C, Sood B, Wiernik PH. A novel second line chemotherapy treatment of recurrent thymoma. Medical Oncology. 1997 Sep;14(3-4):163-168.
Jan, Naveed ; Villani, Gina M. ; Trambert, Jonathan J. ; Fehmian, Carol ; Sood, Brij ; Wiernik, Peter H. / A novel second line chemotherapy treatment of recurrent thymoma. In: Medical Oncology. 1997 ; Vol. 14, No. 3-4. pp. 163-168.
@article{fb16161c93464cd09136a9f545785498,
title = "A novel second line chemotherapy treatment of recurrent thymoma",
abstract = "Thymoma is an uncommon malignancy which is initially treated with surgery. Combined modality treatment with radiation and chemotherapy is utilized in cases of unresectable or metastatic disease. In patients with relapse, a number of different chemotherapeutic regimens have been used with varying success. The case of a male with recurrent thymoma treated with carboplatin and paclitaxel is presented and the literature reviewed. The patient responded to this novel regimen with improvement in clinical symptoms and reduction in tumor mass. This novel regimen has shown activity as second line therapy and merits further investigation as a first line treatment for patients with invasive and or metastatic thymoma.",
keywords = "Carboplatinum, Chemotherapy, Paclitaxel, Thymoma",
author = "Naveed Jan and Villani, {Gina M.} and Trambert, {Jonathan J.} and Carol Fehmian and Brij Sood and Wiernik, {Peter H.}",
year = "1997",
month = "9",
language = "English (US)",
volume = "14",
pages = "163--168",
journal = "Medical Oncology and Tumor Pharmacotherapy",
issn = "0340-7004",
publisher = "Springer Science and Business Media Deutschland GmbH",
number = "3-4",

}

TY - JOUR

T1 - A novel second line chemotherapy treatment of recurrent thymoma

AU - Jan, Naveed

AU - Villani, Gina M.

AU - Trambert, Jonathan J.

AU - Fehmian, Carol

AU - Sood, Brij

AU - Wiernik, Peter H.

PY - 1997/9

Y1 - 1997/9

N2 - Thymoma is an uncommon malignancy which is initially treated with surgery. Combined modality treatment with radiation and chemotherapy is utilized in cases of unresectable or metastatic disease. In patients with relapse, a number of different chemotherapeutic regimens have been used with varying success. The case of a male with recurrent thymoma treated with carboplatin and paclitaxel is presented and the literature reviewed. The patient responded to this novel regimen with improvement in clinical symptoms and reduction in tumor mass. This novel regimen has shown activity as second line therapy and merits further investigation as a first line treatment for patients with invasive and or metastatic thymoma.

AB - Thymoma is an uncommon malignancy which is initially treated with surgery. Combined modality treatment with radiation and chemotherapy is utilized in cases of unresectable or metastatic disease. In patients with relapse, a number of different chemotherapeutic regimens have been used with varying success. The case of a male with recurrent thymoma treated with carboplatin and paclitaxel is presented and the literature reviewed. The patient responded to this novel regimen with improvement in clinical symptoms and reduction in tumor mass. This novel regimen has shown activity as second line therapy and merits further investigation as a first line treatment for patients with invasive and or metastatic thymoma.

KW - Carboplatinum

KW - Chemotherapy

KW - Paclitaxel

KW - Thymoma

UR - http://www.scopus.com/inward/record.url?scp=0031456655&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0031456655&partnerID=8YFLogxK

M3 - Article

C2 - 9468040

AN - SCOPUS:0031456655

VL - 14

SP - 163

EP - 168

JO - Medical Oncology and Tumor Pharmacotherapy

JF - Medical Oncology and Tumor Pharmacotherapy

SN - 0340-7004

IS - 3-4

ER -