A novel missense mutation in lysosomal sulfamidase is the basis of MPS III A in a spontaneous mouse mutant

Medicine & Life Sciences

• N-sulfoglucosamine sulfohydrolase 100%
• Mucopolysaccharidosis III 87%
• Missense Mutation 56%
• heparan sulfate sulfatase 15%
• Glycomics 11%
• Sulfatases 11%
• Lysosomal Storage Diseases 10%
• Heparitin Sulfate 9%
• Cell- and Tissue-Based Therapy 7%
• Genetic Therapy 7%
• Catalytic Domain 7%
• Metals 6%
• Ions 6%
• Amino Acids 5%
• Pathology 4%
• Mutation 4%
• Enzymes 4%
• Genes 3%

Chemical Compounds

• Mutation 45%
• Heparan 43%
• Heparan Sulfate 34%
• Metal Ion 17%
• Acid 9%