A novel human gene whose product shares homology with bovine brain-specific protein p25 is expressed in fetal brain but not in adult brain

Z. Zhang; C. Wu; W. Huang; S. Wang; E. Zhao; Q. Huang; Y. Xie; Y. Mao

doi:10.1007/s100380200037

A novel human gene whose product shares homology with bovine brain-specific protein p25 is expressed in fetal brain but not in adult brain

Z. Zhang, C. Wu, W. Huang, S. Wang, E. Zhao, Q. Huang, Y. Xie, Y. Mao

Research output: Contribution to journal › Article › peer-review

12 Scopus citations

Abstract

We have cloned a novel human gene (C14orf5) from a fetal brain cDNA library that is located on chromosome 14 and consists of 4 exons. It encodes a protein of 170 amino acids that shares homology with human p25 alpha and bovine p25. Reverse transcription-polymerase chain reaction analysis indicated that it is highly expressed in liver and pancreas. Its transcripts could not be detected in adult brain but could be found in fetal brain.

Original language	English (US)
Pages (from-to)	266-268
Number of pages	3
Journal	Journal of Human Genetics
Volume	47
Issue number	5
DOIs	https://doi.org/10.1007/s100380200037
State	Published - 2002
Externally published	Yes

Keywords

Bovine brain-specific p25
CDNA cloning
Human p25 alpha

ASJC Scopus subject areas

Genetics
Genetics(clinical)

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10.1007/s100380200037

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abstract = "We have cloned a novel human gene (C14orf5) from a fetal brain cDNA library that is located on chromosome 14 and consists of 4 exons. It encodes a protein of 170 amino acids that shares homology with human p25 alpha and bovine p25. Reverse transcription-polymerase chain reaction analysis indicated that it is highly expressed in liver and pancreas. Its transcripts could not be detected in adult brain but could be found in fetal brain.",

keywords = "Bovine brain-specific p25, CDNA cloning, Human p25 alpha",

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AU - Zhang, Z.

AU - Wu, C.

AU - Huang, W.

AU - Wang, S.

AU - Zhao, E.

AU - Huang, Q.

AU - Xie, Y.

AU - Mao, Y.

PY - 2002

Y1 - 2002

N2 - We have cloned a novel human gene (C14orf5) from a fetal brain cDNA library that is located on chromosome 14 and consists of 4 exons. It encodes a protein of 170 amino acids that shares homology with human p25 alpha and bovine p25. Reverse transcription-polymerase chain reaction analysis indicated that it is highly expressed in liver and pancreas. Its transcripts could not be detected in adult brain but could be found in fetal brain.

AB - We have cloned a novel human gene (C14orf5) from a fetal brain cDNA library that is located on chromosome 14 and consists of 4 exons. It encodes a protein of 170 amino acids that shares homology with human p25 alpha and bovine p25. Reverse transcription-polymerase chain reaction analysis indicated that it is highly expressed in liver and pancreas. Its transcripts could not be detected in adult brain but could be found in fetal brain.

KW - Bovine brain-specific p25

KW - CDNA cloning

KW - Human p25 alpha

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JF - Journal of Human Genetics

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ER -

A novel human gene whose product shares homology with bovine brain-specific protein p25 is expressed in fetal brain but not in adult brain

Abstract

Keywords

ASJC Scopus subject areas

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