A novel brain stimulation technology provides compatibility with MRI

Peter Serano, Leonardo M. Angelone, Husam Katnani, Emad N. Eskandar, Giorgio Bonmassar

Research output: Contribution to journalArticle

24 Citations (Scopus)

Abstract

Clinical electrical stimulation systems-such as pacemakers and deep brain stimulators (DBS)-are an increasingly common therapeutic option to treat a large range of medical conditions. Despite their remarkable success, one of the significant limitations of these medical devices is the limited compatibility with magnetic resonance imaging (MRI), a standard diagnostic tool in medicine. During an MRI exam, the leads used with these devices, implanted in the body of the patient, act as an electric antenna potentially causing a large amount of energy to be absorbed in the tissue, which can lead to serious heat-related injury. This study presents a novel lead design that reduces the antenna effect and allows for decreased tissue heating during MRI. The optimal parameters of the wire design were determined by a combination of computational modeling and experimental measurements. The results of these simulations were used to build a prototype, which was tested in a gel phantom during an MRI scan. Measurement results showed a three-fold decrease in heating when compared to a commercially available DBS lead. Accordingly, the proposed design may allow a significantly increased number of patients with medical implants to have safe access to the diagnostic benefits of MRI.

Original languageEnglish (US)
Article number9805
JournalScientific Reports
Volume5
DOIs
StatePublished - Apr 29 2015
Externally publishedYes

Fingerprint

Magnetic Resonance Imaging
Technology
Brain
Heating
Equipment and Supplies
Electric Stimulation
Hot Temperature
Gels
Medicine
Wounds and Injuries
Lead
Therapeutics

ASJC Scopus subject areas

  • General

Cite this

A novel brain stimulation technology provides compatibility with MRI. / Serano, Peter; Angelone, Leonardo M.; Katnani, Husam; Eskandar, Emad N.; Bonmassar, Giorgio.

In: Scientific Reports, Vol. 5, 9805, 29.04.2015.

Research output: Contribution to journalArticle

Serano, Peter ; Angelone, Leonardo M. ; Katnani, Husam ; Eskandar, Emad N. ; Bonmassar, Giorgio. / A novel brain stimulation technology provides compatibility with MRI. In: Scientific Reports. 2015 ; Vol. 5.
@article{89963c9820cd4f379e45bd67efd881c6,
title = "A novel brain stimulation technology provides compatibility with MRI",
abstract = "Clinical electrical stimulation systems-such as pacemakers and deep brain stimulators (DBS)-are an increasingly common therapeutic option to treat a large range of medical conditions. Despite their remarkable success, one of the significant limitations of these medical devices is the limited compatibility with magnetic resonance imaging (MRI), a standard diagnostic tool in medicine. During an MRI exam, the leads used with these devices, implanted in the body of the patient, act as an electric antenna potentially causing a large amount of energy to be absorbed in the tissue, which can lead to serious heat-related injury. This study presents a novel lead design that reduces the antenna effect and allows for decreased tissue heating during MRI. The optimal parameters of the wire design were determined by a combination of computational modeling and experimental measurements. The results of these simulations were used to build a prototype, which was tested in a gel phantom during an MRI scan. Measurement results showed a three-fold decrease in heating when compared to a commercially available DBS lead. Accordingly, the proposed design may allow a significantly increased number of patients with medical implants to have safe access to the diagnostic benefits of MRI.",
author = "Peter Serano and Angelone, {Leonardo M.} and Husam Katnani and Eskandar, {Emad N.} and Giorgio Bonmassar",
year = "2015",
month = "4",
day = "29",
doi = "10.1038/srep09805",
language = "English (US)",
volume = "5",
journal = "Scientific Reports",
issn = "2045-2322",
publisher = "Nature Publishing Group",

}

TY - JOUR

T1 - A novel brain stimulation technology provides compatibility with MRI

AU - Serano, Peter

AU - Angelone, Leonardo M.

AU - Katnani, Husam

AU - Eskandar, Emad N.

AU - Bonmassar, Giorgio

PY - 2015/4/29

Y1 - 2015/4/29

N2 - Clinical electrical stimulation systems-such as pacemakers and deep brain stimulators (DBS)-are an increasingly common therapeutic option to treat a large range of medical conditions. Despite their remarkable success, one of the significant limitations of these medical devices is the limited compatibility with magnetic resonance imaging (MRI), a standard diagnostic tool in medicine. During an MRI exam, the leads used with these devices, implanted in the body of the patient, act as an electric antenna potentially causing a large amount of energy to be absorbed in the tissue, which can lead to serious heat-related injury. This study presents a novel lead design that reduces the antenna effect and allows for decreased tissue heating during MRI. The optimal parameters of the wire design were determined by a combination of computational modeling and experimental measurements. The results of these simulations were used to build a prototype, which was tested in a gel phantom during an MRI scan. Measurement results showed a three-fold decrease in heating when compared to a commercially available DBS lead. Accordingly, the proposed design may allow a significantly increased number of patients with medical implants to have safe access to the diagnostic benefits of MRI.

AB - Clinical electrical stimulation systems-such as pacemakers and deep brain stimulators (DBS)-are an increasingly common therapeutic option to treat a large range of medical conditions. Despite their remarkable success, one of the significant limitations of these medical devices is the limited compatibility with magnetic resonance imaging (MRI), a standard diagnostic tool in medicine. During an MRI exam, the leads used with these devices, implanted in the body of the patient, act as an electric antenna potentially causing a large amount of energy to be absorbed in the tissue, which can lead to serious heat-related injury. This study presents a novel lead design that reduces the antenna effect and allows for decreased tissue heating during MRI. The optimal parameters of the wire design were determined by a combination of computational modeling and experimental measurements. The results of these simulations were used to build a prototype, which was tested in a gel phantom during an MRI scan. Measurement results showed a three-fold decrease in heating when compared to a commercially available DBS lead. Accordingly, the proposed design may allow a significantly increased number of patients with medical implants to have safe access to the diagnostic benefits of MRI.

UR - http://www.scopus.com/inward/record.url?scp=84928914315&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84928914315&partnerID=8YFLogxK

U2 - 10.1038/srep09805

DO - 10.1038/srep09805

M3 - Article

C2 - 25924189

AN - SCOPUS:84928914315

VL - 5

JO - Scientific Reports

JF - Scientific Reports

SN - 2045-2322

M1 - 9805

ER -