A new technique for endomyocardial biopsy in infants and small children

Robert H. Pass, Kalyani R. Trivedi, Daphne T. Hsu

Research output: Contribution to journalArticle

3 Scopus citations


Endomyocardial biopsy (EMB) is usually performed from the femoral veins in infants and small children. This requires the use of a long vascular sheath to direct a bioptome to the ventricular septum. We describe a technique of EMB in this population that obviates the need for the use of a long vascular sheath. A 5 Fr 0.038' internal diameter, no-sideholes Cobra catheter (Cook, Bloomington, IN) introduced via a 5 Fr short sheath was used to direct a 3 Fr, 60-cm-length Cook bioptome to the ventricular septum. From January 1998 to August 1999, this technique was used 22 times in seven patients for EMB (median, age 13 months; range, 1-72 months). Indications for EMB in this group were posttransplantation surveillance (21 times) and evaluation for cardiomyopathy/myocarditis (1). Median number of EMB specimens obtained per procedure was 6 (range, 5-9). There was one pneumopericardium seen post-EMB with this technique without hemodynamic embarrassment. EMB in infants and small children can be performed successfully, safely, and repeatedly from the femoral veins without the need for a long sheath.(C) 2000 Wiley-Liss, Inc.

Original languageEnglish (US)
Pages (from-to)441-444
Number of pages4
JournalCatheterization and Cardiovascular Interventions
Issue number4
StatePublished - Aug 15 2000



  • Bioptome
  • Cardiomyopathy
  • Pediatrics
  • Transplantation

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine

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