A new protein that gels F actin in the cell cortex of Dictyostelium discoideum

John Coudeelis; Jaffrey Salisbury; Keigi Fujiwara

doi:10.1038/292161a0

A new protein that gels F actin in the cell cortex of Dictyostelium discoideum

John Coudeelis, Jaffrey Salisbury, Keigi Fujiwara

Anatomy & Structural Biology

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Abstract

It is thought that the dense actin filament networks found in the cortex of many cell types^1-4 might account for the gelled consistency of the cortex⁵ and the exclusion of other organelles from this region of the cytoplasm^6-8. We now demonstrate that a new actin-binding protein from Dictyostelium that gels actin in vitro is concentrated in the cell cortex, suggesting that this protein, in association with actin, accounts for the gel-like properties of this region of the cell.

Original language	English (US)
Pages (from-to)	161-162
Number of pages	2
Journal	Nature
Volume	292
Issue number	5819
DOIs	https://doi.org/10.1038/292161a0
State	Published - Dec 1 1981

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abstract = "It is thought that the dense actin filament networks found in the cortex of many cell types1-4 might account for the gelled consistency of the cortex5 and the exclusion of other organelles from this region of the cytoplasm6-8. We now demonstrate that a new actin-binding protein from Dictyostelium that gels actin in vitro is concentrated in the cell cortex, suggesting that this protein, in association with actin, accounts for the gel-like properties of this region of the cell.",

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AU - Coudeelis, John

AU - Salisbury, Jaffrey

AU - Fujiwara, Keigi

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Y1 - 1981/12/1

N2 - It is thought that the dense actin filament networks found in the cortex of many cell types1-4 might account for the gelled consistency of the cortex5 and the exclusion of other organelles from this region of the cytoplasm6-8. We now demonstrate that a new actin-binding protein from Dictyostelium that gels actin in vitro is concentrated in the cell cortex, suggesting that this protein, in association with actin, accounts for the gel-like properties of this region of the cell.

AB - It is thought that the dense actin filament networks found in the cortex of many cell types1-4 might account for the gelled consistency of the cortex5 and the exclusion of other organelles from this region of the cytoplasm6-8. We now demonstrate that a new actin-binding protein from Dictyostelium that gels actin in vitro is concentrated in the cell cortex, suggesting that this protein, in association with actin, accounts for the gel-like properties of this region of the cell.

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A new protein that gels F actin in the cell cortex of Dictyostelium discoideum

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