A new protein that gels F actin in the cell cortex of Dictyostelium discoideum

John S. Condeelis, Jaffrey Salisbury, Keigi Fujiwara

Research output: Contribution to journalArticle

27 Citations (Scopus)

Abstract

It is thought that the dense actin filament networks found in the cortex of many cell types1-4 might account for the gelled consistency of the cortex5 and the exclusion of other organelles from this region of the cytoplasm6-8. We now demonstrate that a new actin-binding protein from Dictyostelium that gels actin in vitro is concentrated in the cell cortex, suggesting that this protein, in association with actin, accounts for the gel-like properties of this region of the cell.

Original languageEnglish (US)
Pages (from-to)161-162
Number of pages2
JournalNature
Volume292
Issue number5819
DOIs
StatePublished - 1981

Fingerprint

Dictyostelium
Actins
Gels
Microfilament Proteins
Proteins
Actin Cytoskeleton
Organelles

ASJC Scopus subject areas

  • General

Cite this

A new protein that gels F actin in the cell cortex of Dictyostelium discoideum. / Condeelis, John S.; Salisbury, Jaffrey; Fujiwara, Keigi.

In: Nature, Vol. 292, No. 5819, 1981, p. 161-162.

Research output: Contribution to journalArticle

Condeelis, John S. ; Salisbury, Jaffrey ; Fujiwara, Keigi. / A new protein that gels F actin in the cell cortex of Dictyostelium discoideum. In: Nature. 1981 ; Vol. 292, No. 5819. pp. 161-162.
@article{55aeeb11a3d34896a4e4f0b29f211a84,
title = "A new protein that gels F actin in the cell cortex of Dictyostelium discoideum",
abstract = "It is thought that the dense actin filament networks found in the cortex of many cell types1-4 might account for the gelled consistency of the cortex5 and the exclusion of other organelles from this region of the cytoplasm6-8. We now demonstrate that a new actin-binding protein from Dictyostelium that gels actin in vitro is concentrated in the cell cortex, suggesting that this protein, in association with actin, accounts for the gel-like properties of this region of the cell.",
author = "Condeelis, {John S.} and Jaffrey Salisbury and Keigi Fujiwara",
year = "1981",
doi = "10.1038/292161a0",
language = "English (US)",
volume = "292",
pages = "161--162",
journal = "Nature",
issn = "0028-0836",
publisher = "Nature Publishing Group",
number = "5819",

}

TY - JOUR

T1 - A new protein that gels F actin in the cell cortex of Dictyostelium discoideum

AU - Condeelis, John S.

AU - Salisbury, Jaffrey

AU - Fujiwara, Keigi

PY - 1981

Y1 - 1981

N2 - It is thought that the dense actin filament networks found in the cortex of many cell types1-4 might account for the gelled consistency of the cortex5 and the exclusion of other organelles from this region of the cytoplasm6-8. We now demonstrate that a new actin-binding protein from Dictyostelium that gels actin in vitro is concentrated in the cell cortex, suggesting that this protein, in association with actin, accounts for the gel-like properties of this region of the cell.

AB - It is thought that the dense actin filament networks found in the cortex of many cell types1-4 might account for the gelled consistency of the cortex5 and the exclusion of other organelles from this region of the cytoplasm6-8. We now demonstrate that a new actin-binding protein from Dictyostelium that gels actin in vitro is concentrated in the cell cortex, suggesting that this protein, in association with actin, accounts for the gel-like properties of this region of the cell.

UR - http://www.scopus.com/inward/record.url?scp=0019499820&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0019499820&partnerID=8YFLogxK

U2 - 10.1038/292161a0

DO - 10.1038/292161a0

M3 - Article

VL - 292

SP - 161

EP - 162

JO - Nature

JF - Nature

SN - 0028-0836

IS - 5819

ER -