Abstract
A new iron-binding protein contained in guinea pig intestinal mucosa has been purified to homogeneity. The protein has a molecular weight of 78,000 in a nondissociating system and 43,000 in SDS-gel electrophoresis. It binds approximately 2 moles of iron per mole with a formation constant of 1019 at pH 7. It is distinguished from transferrin and lactoferrin by differences on DEAE-Sephadex chromatography and spectroscopy and by its failure to cross-react with antisera to these other iron-binding proteins.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 670-679 |
| Number of pages | 10 |
| Journal | The Journal of Laboratory and Clinical Medicine |
| Volume | 87 |
| Issue number | 4 |
| State | Published - Apr 1976 |
| Externally published | Yes |
ASJC Scopus subject areas
- Pathology and Forensic Medicine