A marked potentiating effect in man of combined pancuronium and metocurine or pancuronium and d-tubocurarine neuromuscular blockade

Philip W. Lebowitz, F. M. Ramsey, J. J. Savarese, H. H. Ali

Research output: Contribution to journalArticle

Abstract

Comparison of ED95 values may be made in terms of relaxant-equivalents, i.e., 1 relaxant-equivalent = .005 mg/kg of pancuronium = .02 mg/kg of metocurine = .03 mg/kg of dTc. Isobolograms constructed from this data indicate that pancuronium-metocurine and pancuronium-dTc both displayed greater than additive neuromuscular blocking potency. This marked potentiation was not seen with the metocurine-dTc combination.

Original languageEnglish (US)
JournalAnesthesiology
Volume51
Issue number3 SUPPL
StatePublished - 1979
Externally publishedYes

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Pancuronium
Tubocurarine
Neuromuscular Blockade
metocurine

ASJC Scopus subject areas

  • Anesthesiology and Pain Medicine

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A marked potentiating effect in man of combined pancuronium and metocurine or pancuronium and d-tubocurarine neuromuscular blockade. / Lebowitz, Philip W.; Ramsey, F. M.; Savarese, J. J.; Ali, H. H.

In: Anesthesiology, Vol. 51, No. 3 SUPPL, 1979.

Research output: Contribution to journalArticle

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AU - Ramsey, F. M.

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AU - Ali, H. H.

PY - 1979

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