Abstract
Visual object-recognition is thought to involve activation of a distributed network of cortical regions, nodes of which include the lateral prefrontal cortex, the so-called lateral occipital complex (LOC), and the hippocampal formation. It has been proposed that long-range oscillatory synchronization is a major mode of coordinating such a distributed network. Here, intracranial recordings were made from three humans as they performed a challenging visual object-recognition task that required them to identify barely recognizable fragmented line-drawings of common objects. Subdural electrodes were placed over the prefrontal cortex and LOC, and depth electrodes were placed within the hippocampal formation. Robust beta-band coherence was evident in all subjects during processing of recognizable fragmented images. Significantly lower coherence was evident during processing of unrecognizable scrambled versions of the same. The results indicate that transient beta-band oscillatory coupling between these three distributed cortical regions may reflect a mechanism for effective communication during visual object processing.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 4399-4404 |
| Number of pages | 6 |
| Journal | Proceedings of the National Academy of Sciences of the United States of America |
| Volume | 105 |
| Issue number | 11 |
| DOIs | |
| State | Published - Mar 18 2008 |
| Externally published | Yes |
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Keywords
- Beta oscillations
- EEG
- Hippocampus
- Perceptual closure
- Vision
ASJC Scopus subject areas
- Genetics
- General
Cite this
A human intracranial study of long-range oscillatory coherence across a frontal-occipital-hippocampal brain network during visual object processing. / Sehatpour, Pejman; Molholm, Sophie; Schwartz, Theodore H.; Mahoney, Jeannette R.; Mehta, Ashesh D.; Javitt, Daniel C.; Stanton, Patric K.; Foxe, John J.
In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, No. 11, 18.03.2008, p. 4399-4404.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - A human intracranial study of long-range oscillatory coherence across a frontal-occipital-hippocampal brain network during visual object processing
AU - Sehatpour, Pejman
AU - Molholm, Sophie
AU - Schwartz, Theodore H.
AU - Mahoney, Jeannette R.
AU - Mehta, Ashesh D.
AU - Javitt, Daniel C.
AU - Stanton, Patric K.
AU - Foxe, John J.
PY - 2008/3/18
Y1 - 2008/3/18
N2 - Visual object-recognition is thought to involve activation of a distributed network of cortical regions, nodes of which include the lateral prefrontal cortex, the so-called lateral occipital complex (LOC), and the hippocampal formation. It has been proposed that long-range oscillatory synchronization is a major mode of coordinating such a distributed network. Here, intracranial recordings were made from three humans as they performed a challenging visual object-recognition task that required them to identify barely recognizable fragmented line-drawings of common objects. Subdural electrodes were placed over the prefrontal cortex and LOC, and depth electrodes were placed within the hippocampal formation. Robust beta-band coherence was evident in all subjects during processing of recognizable fragmented images. Significantly lower coherence was evident during processing of unrecognizable scrambled versions of the same. The results indicate that transient beta-band oscillatory coupling between these three distributed cortical regions may reflect a mechanism for effective communication during visual object processing.
AB - Visual object-recognition is thought to involve activation of a distributed network of cortical regions, nodes of which include the lateral prefrontal cortex, the so-called lateral occipital complex (LOC), and the hippocampal formation. It has been proposed that long-range oscillatory synchronization is a major mode of coordinating such a distributed network. Here, intracranial recordings were made from three humans as they performed a challenging visual object-recognition task that required them to identify barely recognizable fragmented line-drawings of common objects. Subdural electrodes were placed over the prefrontal cortex and LOC, and depth electrodes were placed within the hippocampal formation. Robust beta-band coherence was evident in all subjects during processing of recognizable fragmented images. Significantly lower coherence was evident during processing of unrecognizable scrambled versions of the same. The results indicate that transient beta-band oscillatory coupling between these three distributed cortical regions may reflect a mechanism for effective communication during visual object processing.
KW - Beta oscillations
KW - EEG
KW - Hippocampus
KW - Perceptual closure
KW - Vision
UR - http://www.scopus.com/inward/record.url?scp=41949087747&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=41949087747&partnerID=8YFLogxK
U2 - 10.1073/pnas.0708418105
DO - 10.1073/pnas.0708418105
M3 - Article
C2 - 18334648
AN - SCOPUS:41949087747
VL - 105
SP - 4399
EP - 4404
JO - Proceedings of the National Academy of Sciences of the United States of America
JF - Proceedings of the National Academy of Sciences of the United States of America
SN - 0027-8424
IS - 11
ER -