Abstract
A stable, biologically active glycosylated insulin derivative that is complementary to the major combining site of concanavalin A has been synthesized. Hormone release is proportional to the quantity of glucose present. Glucose regulation of exogenous insulin delivery could have important applications in the therapy of diabetes mellitus.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 1190-1191 |
| Number of pages | 2 |
| Journal | Science |
| Volume | 206 |
| Issue number | 4423 |
| DOIs | |
| State | Published - Jan 1 1979 |
ASJC Scopus subject areas
- General
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Cite this
Brownlee, M., & Cerami, A. (1979). A glucose-controlled insulin-delivery system: Semisynthetic insulin bound to lectin. Science, 206(4423), 1190-1191. https://doi.org/10.1126/science.505005