@inbook{c3a48045203841b1a1b5446f6a617109,
title = "A fluorescence-based assay for identification of bacterial topoisomerase I poisons",
abstract = "Bacterial Topoisomerase I is a potential target for the identification of novel topoisomerase poison inhibitors that could provide leads for a new class of antibacterial compounds. Here we describe in detail a fluorescence-based cleavage assay that is successfully used in HTS for the discovery of bacterial topoisomerase Ι poisons.",
keywords = "Bacterial topoisomerase I, Fluorescence-based assay, High-throughput screening, Topoisomerase I poisons",
author = "Thirunavukkarasu Annamalai and Bokun Cheng and Neelam Keswani and Tse-Dinh, {Yuk Ching}",
year = "2018",
month = jan,
day = "1",
doi = "10.1007/978-1-4939-7459-7_18",
language = "English (US)",
series = "Methods in Molecular Biology",
publisher = "Humana Press Inc.",
pages = "259--268",
booktitle = "Methods in Molecular Biology",
}