A farnesyltransferase inhibitor activates lysosomes and reduces tau pathology in mice with tauopathy

Israel Hernandez, Gabriel Luna, Jennifer N. Rauch, Surya A. Reis, Michel Giroux, Celeste M. Karch, Daniel Boctor, Youssef E. Sibih, Nadia J. Storm, Antonio Diaz, Susmita Kaushik, Cezary Zekanowski, Alexander A. Kang, Cassidy R. Hinman, Vesna Cerovac, Elmer Guzman, Honjun Zhou, Stephen J. Haggarty, Alison M. Goate, Steven K. FisherAna M. Cuervo, Kenneth S. Kosik

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Medicine & Life Sciences