A diet high in low-fat dairy products lowers diabetes risk in postmenopausal women

Karen L. Margolis, Feifei Wei, Ian H. de Boer, Barbara V. Howard, Simin Liu, JoAnn E. Manson, Yasmin Mossavar-Rahmani, Lawrence S. Phillips, James M. Shikany, Lesley F. Tinker

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54 Citations (Scopus)

Abstract

Some previous studies have suggested that consuming dairy products, particularly the low-fat variety, lowers the incidence of type 2 diabetes. However, no study to our knowledge has focused on an ethnically diverse group of postmenopausal women, a population with a high risk of this disease. We conducted a prospective cohort study of 82,076 postmenopausal women enrolled in the Women's Health Initiative Observational Study who did not report diabetes at enrollment. Total, low-fat, and high-fat dairy product and yogurt intakes were estimated from FFQ at baseline and 3 y of follow-up. Treated diabetes incidence was ascertained from annual follow-up questionnaires. During 8 y of follow-up, 3946 cases of incident treated diabetes were reported (annual incidence, 0.73%; cumulative incidence, 4.8%). After multivariable adjustment, low-fat dairy product consumption was inversely associated with the risk of type 2 diabetes. RR was roughly 0.5-0.6 in the upper quintiles compared with the lowest quintile (median servings/d, 2.8 in the 5th quintile and 1.5 in the 4th quintile vs. 0.05 in the first quintile; P-trend, 0.001). The inverse relationship was more pronounced in women with a higher BMI. High yogurt consumption was associated with a significant decrease in diabetes risk, whereas there was no relationship between high-fat dairy product consumption and diabetes risk. A diet high in low-fat dairy products is associated with lower diabetes risk in postmenopausal women, particularly those who are obese.

Original languageEnglish (US)
Pages (from-to)1969-1974
Number of pages6
JournalJournal of Nutrition
Volume141
Issue number11
DOIs
StatePublished - Nov 1 2011

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Dairy Products
Fats
Diet
Yogurt
Incidence
Type 2 Diabetes Mellitus
Women's Health
Observational Studies
Cohort Studies
Prospective Studies
Population

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Nutrition and Dietetics

Cite this

Margolis, K. L., Wei, F., de Boer, I. H., Howard, B. V., Liu, S., Manson, J. E., ... Tinker, L. F. (2011). A diet high in low-fat dairy products lowers diabetes risk in postmenopausal women. Journal of Nutrition, 141(11), 1969-1974. https://doi.org/10.3945/jn.111.143339

A diet high in low-fat dairy products lowers diabetes risk in postmenopausal women. / Margolis, Karen L.; Wei, Feifei; de Boer, Ian H.; Howard, Barbara V.; Liu, Simin; Manson, JoAnn E.; Mossavar-Rahmani, Yasmin; Phillips, Lawrence S.; Shikany, James M.; Tinker, Lesley F.

In: Journal of Nutrition, Vol. 141, No. 11, 01.11.2011, p. 1969-1974.

Research output: Contribution to journalArticle

Margolis, KL, Wei, F, de Boer, IH, Howard, BV, Liu, S, Manson, JE, Mossavar-Rahmani, Y, Phillips, LS, Shikany, JM & Tinker, LF 2011, 'A diet high in low-fat dairy products lowers diabetes risk in postmenopausal women', Journal of Nutrition, vol. 141, no. 11, pp. 1969-1974. https://doi.org/10.3945/jn.111.143339
Margolis KL, Wei F, de Boer IH, Howard BV, Liu S, Manson JE et al. A diet high in low-fat dairy products lowers diabetes risk in postmenopausal women. Journal of Nutrition. 2011 Nov 1;141(11):1969-1974. https://doi.org/10.3945/jn.111.143339
Margolis, Karen L. ; Wei, Feifei ; de Boer, Ian H. ; Howard, Barbara V. ; Liu, Simin ; Manson, JoAnn E. ; Mossavar-Rahmani, Yasmin ; Phillips, Lawrence S. ; Shikany, James M. ; Tinker, Lesley F. / A diet high in low-fat dairy products lowers diabetes risk in postmenopausal women. In: Journal of Nutrition. 2011 ; Vol. 141, No. 11. pp. 1969-1974.
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