A Designer Quest for the Achilles’ Heel of Influenza

J. Eduardo Fajardo; Andras Fiser

doi:10.1016/j.str.2020.09.004

A Designer Quest for the Achilles’ Heel of Influenza

J. Eduardo Fajardo, Andras Fiser

Systems & Computational Biology

Research output: Contribution to journal › Comment/debate › peer-review

Abstract

Monoclonal antibodies are attractive but, in certain applications, limited therapeutic modalities due to their large size and high specificity. In this issue of Structure, Sevy at al. describe a computationally designed cyclic peptide mimicking the CDRH3 loop of the C05 antibody against influenza showing the potential utility of designer biologics.

Original language	English (US)
Pages (from-to)	1083-1084
Number of pages	2
Journal	Structure
Volume	28
Issue number	10
DOIs	https://doi.org/10.1016/j.str.2020.09.004
State	Published - Oct 6 2020

ASJC Scopus subject areas

Structural Biology
Molecular Biology

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10.1016/j.str.2020.09.004

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title = "A Designer Quest for the Achilles{\textquoteright} Heel of Influenza",

abstract = "Monoclonal antibodies are attractive but, in certain applications, limited therapeutic modalities due to their large size and high specificity. In this issue of Structure, Sevy at al. describe a computationally designed cyclic peptide mimicking the CDRH3 loop of the C05 antibody against influenza showing the potential utility of designer biologics.",

author = "Fajardo, {J. Eduardo} and Andras Fiser",

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year = "2020",

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AU - Fiser, Andras

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AB - Monoclonal antibodies are attractive but, in certain applications, limited therapeutic modalities due to their large size and high specificity. In this issue of Structure, Sevy at al. describe a computationally designed cyclic peptide mimicking the CDRH3 loop of the C05 antibody against influenza showing the potential utility of designer biologics.

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A Designer Quest for the Achilles’ Heel of Influenza

Abstract

ASJC Scopus subject areas

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