TY - JOUR
T1 - A convenient synthesis of 5-alkylthio-3,4-diarylisoxazoles by palladium-catalyzed coupling reactions
AU - Eskandari, Roozbeh
AU - Navidpour, Latifeh
AU - Amini, Mohsen
AU - Shafaroodi, Hamed
AU - Shafiee, Abbas
PY - 2007
Y1 - 2007
N2 - (Chemical Equation Presented) Palladium-catalyzed coupling reaction was found effective for rapid access to pharmacologically interesting 3,4-diarylisoxazoles derivatives as selective COX-2 inhibitors. Thus, the coupling reaction between 5-alkylthio-3-aryl-4-iodoisoxazoles and arylboronic acids afforded the target 5-alkylthio-3,4-diarylisoxazoles in good yields.
AB - (Chemical Equation Presented) Palladium-catalyzed coupling reaction was found effective for rapid access to pharmacologically interesting 3,4-diarylisoxazoles derivatives as selective COX-2 inhibitors. Thus, the coupling reaction between 5-alkylthio-3-aryl-4-iodoisoxazoles and arylboronic acids afforded the target 5-alkylthio-3,4-diarylisoxazoles in good yields.
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U2 - 10.1002/jhet.5570440227
DO - 10.1002/jhet.5570440227
M3 - Article
AN - SCOPUS:36749054643
SN - 0022-152X
VL - 44
SP - 449
EP - 453
JO - Journal of Heterocyclic Chemistry
JF - Journal of Heterocyclic Chemistry
IS - 2
ER -