A comparison of buprenorphine induction strategies: Patient-centered home-based inductions versus standard-of-care office-based inductions

Chinazo O. Cunningham, Angela Giovanniello, Xuan Li, Hillary V. Kunins, Robert J. Roose, Nancy L. Sohler

Research output: Contribution to journalArticle

20 Citations (Scopus)

Abstract

Although novel buprenorphine induction strategies are emerging, they have been inadequately studied. To examine our newly developed patient-centered home-based inductions, we conducted a subgroup analysis of 79 opioid-dependent individuals who had buprenorphine inductions at an urban community health center. Participants chose their induction strategy. Standard-of-care office-based inductions were physician driven, with multiple assessments, and observed, and the patient-centered home-based inductions emphasized patient self-management and included a "kit" for induction at home. We conducted interviews and extracted medical records. Using mixed nonlinear models, we examined associations between induction strategy and opioid use and any drug use. Compared with those with standard-of-care office-based inductions, participants with patient-centered home-based inductions had no significant differences in opioid use (adjusted odds ratio [AOR] = 0.63, 95% confidence interval [CI] = 0.13-2.97) but greater reductions in any drug use (AOR = 0.05, 95% CI = 0.01-0.37). Taking into account the limitations of our observational cohort study design, we conclude that participants with patient-centered home-based inductions had similar reductions in opioid use and greater reductions in any drug use than those with standard-of-care office-based inductions. It is essential that new induction strategies be based on existing models or theories and be well studied.

Original languageEnglish (US)
Pages (from-to)349-356
Number of pages8
JournalJournal of Substance Abuse Treatment
Volume40
Issue number4
DOIs
StatePublished - Jun 2011

Fingerprint

Buprenorphine
Standard of Care
Opioid Analgesics
Odds Ratio
Pharmaceutical Preparations
Confidence Intervals
Urban Health
Community Health Centers
Nonlinear Dynamics
Self Care
Medical Records
Observational Studies
Cohort Studies
Interviews
Physicians

Keywords

  • Buprenorphine
  • Buprenorphine induction
  • Drug use
  • Opioid
  • Opioid addiction treatment
  • Primary care

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Clinical Psychology
  • Phychiatric Mental Health
  • Medicine (miscellaneous)

Cite this

A comparison of buprenorphine induction strategies : Patient-centered home-based inductions versus standard-of-care office-based inductions. / Cunningham, Chinazo O.; Giovanniello, Angela; Li, Xuan; Kunins, Hillary V.; Roose, Robert J.; Sohler, Nancy L.

In: Journal of Substance Abuse Treatment, Vol. 40, No. 4, 06.2011, p. 349-356.

Research output: Contribution to journalArticle

Cunningham, Chinazo O. ; Giovanniello, Angela ; Li, Xuan ; Kunins, Hillary V. ; Roose, Robert J. ; Sohler, Nancy L. / A comparison of buprenorphine induction strategies : Patient-centered home-based inductions versus standard-of-care office-based inductions. In: Journal of Substance Abuse Treatment. 2011 ; Vol. 40, No. 4. pp. 349-356.
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