A case of renal cell carcinoma after successful treatment of Wilms tumor

Barrie S. Rich; Maureen P. McEvoy; Michael P. La Quaglia

doi:10.1016/j.jpedsurg.2010.06.032

A case of renal cell carcinoma after successful treatment of Wilms tumor

Barrie S. Rich, Maureen P. McEvoy, Michael P. La Quaglia

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

Abstract

This case report documents the eighth reported case of renal cell carcinoma (RCC) occurring after treatment of Wilms tumor. Although secondary malignancies after treatment of Wilms tumors are not infrequent, RCC as the second malignancy is rare. We discuss a 17-year-old girl whose RCC was diagnosed 12.5 years after diagnosis of a Wilms tumor. In addition, we review the literature on the subject. Renal cell carcinoma has been proposed as a consequent of chemoradiation; however, a genetic susceptibility must be considered. Because it is routine to assess the functional status of the remaining solitary kidney by annual ultrasonography, we recommend assessing for the presence of secondary renal malignancies and perhaps continuing routine ultrasounds long-term.

Original language	English (US)
Pages (from-to)	1883-1886
Number of pages	4
Journal	Journal of Pediatric Surgery
Volume	45
Issue number	9
DOIs	https://doi.org/10.1016/j.jpedsurg.2010.06.032
State	Published - Sep 2010
Externally published	Yes

Keywords

Renal cell carcinoma
Secondary malignancy
Wilms tumor

ASJC Scopus subject areas

Surgery
Pediatrics, Perinatology, and Child Health

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10.1016/j.jpedsurg.2010.06.032

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title = "A case of renal cell carcinoma after successful treatment of Wilms tumor",

abstract = "This case report documents the eighth reported case of renal cell carcinoma (RCC) occurring after treatment of Wilms tumor. Although secondary malignancies after treatment of Wilms tumors are not infrequent, RCC as the second malignancy is rare. We discuss a 17-year-old girl whose RCC was diagnosed 12.5 years after diagnosis of a Wilms tumor. In addition, we review the literature on the subject. Renal cell carcinoma has been proposed as a consequent of chemoradiation; however, a genetic susceptibility must be considered. Because it is routine to assess the functional status of the remaining solitary kidney by annual ultrasonography, we recommend assessing for the presence of secondary renal malignancies and perhaps continuing routine ultrasounds long-term.",

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T1 - A case of renal cell carcinoma after successful treatment of Wilms tumor

AU - Rich, Barrie S.

AU - McEvoy, Maureen P.

AU - La Quaglia, Michael P.

PY - 2010/9

Y1 - 2010/9

N2 - This case report documents the eighth reported case of renal cell carcinoma (RCC) occurring after treatment of Wilms tumor. Although secondary malignancies after treatment of Wilms tumors are not infrequent, RCC as the second malignancy is rare. We discuss a 17-year-old girl whose RCC was diagnosed 12.5 years after diagnosis of a Wilms tumor. In addition, we review the literature on the subject. Renal cell carcinoma has been proposed as a consequent of chemoradiation; however, a genetic susceptibility must be considered. Because it is routine to assess the functional status of the remaining solitary kidney by annual ultrasonography, we recommend assessing for the presence of secondary renal malignancies and perhaps continuing routine ultrasounds long-term.

AB - This case report documents the eighth reported case of renal cell carcinoma (RCC) occurring after treatment of Wilms tumor. Although secondary malignancies after treatment of Wilms tumors are not infrequent, RCC as the second malignancy is rare. We discuss a 17-year-old girl whose RCC was diagnosed 12.5 years after diagnosis of a Wilms tumor. In addition, we review the literature on the subject. Renal cell carcinoma has been proposed as a consequent of chemoradiation; however, a genetic susceptibility must be considered. Because it is routine to assess the functional status of the remaining solitary kidney by annual ultrasonography, we recommend assessing for the presence of secondary renal malignancies and perhaps continuing routine ultrasounds long-term.

KW - Renal cell carcinoma

KW - Secondary malignancy

KW - Wilms tumor

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JO - Journal of Pediatric Surgery

JF - Journal of Pediatric Surgery

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A case of renal cell carcinoma after successful treatment of Wilms tumor

Abstract

Keywords

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