Clozapine has been reported to cause acute renal failure due to acute interstitial nephritis. We discuss a case of clozapine-induced acute renal failure and compare it to 7 other cases reported in the literature. We review the signs and symptoms of the hypersensitivity response, such as fever and eosinophilia, caused by clozapine and make recommendations for early detection. Early detection and prompt discontinuation of clozapine can prevent renal damage, as can the avoidance of other nephrotoxic drugs like antibiotics.
|Original language||English (US)|
|Journal||Primary Care Companion to the Journal of Clinical Psychiatry|
|State||Published - Jul 18 2011|
ASJC Scopus subject areas
- Psychiatry and Mental health