A case of acute renal failure in a patient recently treated with clozapine and a review of previously reported cases

J. Daniel Kanofsky; Mary E. Woesner; Alexander Z. Harris; James P. Kelleher; Karen Gittens; Elina Jerschow

doi:10.4088/PCC.10br01091

A case of acute renal failure in a patient recently treated with clozapine and a review of previously reported cases

J. Daniel Kanofsky, Mary E. Woesner, Alexander Z. Harris, James P. Kelleher, Karen Gittens, Elina Jerschow

Medicine

Research output: Contribution to journal › Review article › peer-review

21 Scopus citations

Abstract

Clozapine has been reported to cause acute renal failure due to acute interstitial nephritis. We discuss a case of clozapine-induced acute renal failure and compare it to 7 other cases reported in the literature. We review the signs and symptoms of the hypersensitivity response, such as fever and eosinophilia, caused by clozapine and make recommendations for early detection. Early detection and prompt discontinuation of clozapine can prevent renal damage, as can the avoidance of other nephrotoxic drugs like antibiotics.

Original language	English (US)
Journal	Primary Care Companion to the Journal of Clinical Psychiatry
Volume	13
Issue number	3
DOIs	https://doi.org/10.4088/PCC.10br01091
State	Published - 2011

ASJC Scopus subject areas

Psychiatry and Mental health

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.4088/PCC.10br01091

Cite this

@article{dd8ea784a787462b99629a8cff91b00d,

title = "A case of acute renal failure in a patient recently treated with clozapine and a review of previously reported cases",

abstract = "Clozapine has been reported to cause acute renal failure due to acute interstitial nephritis. We discuss a case of clozapine-induced acute renal failure and compare it to 7 other cases reported in the literature. We review the signs and symptoms of the hypersensitivity response, such as fever and eosinophilia, caused by clozapine and make recommendations for early detection. Early detection and prompt discontinuation of clozapine can prevent renal damage, as can the avoidance of other nephrotoxic drugs like antibiotics.",

author = "{Daniel Kanofsky}, J. and Woesner, {Mary E.} and Harris, {Alexander Z.} and Kelleher, {James P.} and Karen Gittens and Elina Jerschow",

year = "2011",

doi = "10.4088/PCC.10br01091",

language = "English (US)",

volume = "13",

journal = "Primary Care Companion to the Journal of Clinical Psychiatry",

issn = "1523-5998",

publisher = "Physicians Postgraduate Press Inc.",

number = "3",

}

TY - JOUR

T1 - A case of acute renal failure in a patient recently treated with clozapine and a review of previously reported cases

AU - Daniel Kanofsky, J.

AU - Woesner, Mary E.

AU - Harris, Alexander Z.

AU - Kelleher, James P.

AU - Gittens, Karen

AU - Jerschow, Elina

PY - 2011

Y1 - 2011

N2 - Clozapine has been reported to cause acute renal failure due to acute interstitial nephritis. We discuss a case of clozapine-induced acute renal failure and compare it to 7 other cases reported in the literature. We review the signs and symptoms of the hypersensitivity response, such as fever and eosinophilia, caused by clozapine and make recommendations for early detection. Early detection and prompt discontinuation of clozapine can prevent renal damage, as can the avoidance of other nephrotoxic drugs like antibiotics.

AB - Clozapine has been reported to cause acute renal failure due to acute interstitial nephritis. We discuss a case of clozapine-induced acute renal failure and compare it to 7 other cases reported in the literature. We review the signs and symptoms of the hypersensitivity response, such as fever and eosinophilia, caused by clozapine and make recommendations for early detection. Early detection and prompt discontinuation of clozapine can prevent renal damage, as can the avoidance of other nephrotoxic drugs like antibiotics.

UR - http://www.scopus.com/inward/record.url?scp=79960269097&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=79960269097&partnerID=8YFLogxK

U2 - 10.4088/PCC.10br01091

DO - 10.4088/PCC.10br01091

M3 - Review article

C2 - 21977363

AN - SCOPUS:79960269097

SN - 1523-5998

VL - 13

JO - Primary Care Companion to the Journal of Clinical Psychiatry

JF - Primary Care Companion to the Journal of Clinical Psychiatry

IS - 3

ER -

A case of acute renal failure in a patient recently treated with clozapine and a review of previously reported cases

Abstract

ASJC Scopus subject areas

UN SDGs

Access to Document

Other files and links

Fingerprint

Cite this