A case of acute renal failure in a patient recently treated with clozapine and a review of previously reported cases

J. Daniel Kanofsky, Mary E. Woesner, Alexander Z. Harris, James P. Kelleher, Karen Gittens, Elina Jerschow

Research output: Contribution to journalReview article

15 Scopus citations

Abstract

Clozapine has been reported to cause acute renal failure due to acute interstitial nephritis. We discuss a case of clozapine-induced acute renal failure and compare it to 7 other cases reported in the literature. We review the signs and symptoms of the hypersensitivity response, such as fever and eosinophilia, caused by clozapine and make recommendations for early detection. Early detection and prompt discontinuation of clozapine can prevent renal damage, as can the avoidance of other nephrotoxic drugs like antibiotics.

Original languageEnglish (US)
JournalPrimary Care Companion to the Journal of Clinical Psychiatry
Volume13
Issue number3
DOIs
StatePublished - Jul 18 2011

ASJC Scopus subject areas

  • Psychiatry and Mental health

Fingerprint Dive into the research topics of 'A case of acute renal failure in a patient recently treated with clozapine and a review of previously reported cases'. Together they form a unique fingerprint.

  • Cite this