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  Targeting a novel Plasmodium falciparum purine recycling pathway with specific immucillins

  Ting, L. M., Shi, W., Lewandowicz, A., Singh, V., Mwakingwe, A., Birck, M. R., Taylor Ringia, E. A., Bench, G., Madrid, D. C., Tyler, P. C., Evans, G. B., Furneaux, R. H., Schramm, V. L. & Kim, K., Mar 11 2005, In: Journal of Biological Chemistry. 280, 10, p. 9547-9554 8 p.

  Research output: Contribution to journal › Article › peer-review
  111 Scopus citations

• Targeting Bcl-2 family members with the BH3 mimetic AT-101 markedly enhances the therapeutic effects of chemotherapeutic agents in in vitro and in vivo models of B-cell lymphoma

  Paoluzzi, L., Gonen, M., Gardner, J. R., Mastrella, J., Yang, D., Holmlund, J., Sorensen, M., Leopold, L., Manova, K., Marcucci, G., Heaney, M. L. & O'Connor, O. A., Jun 1 2008, In: Blood. 111, 11, p. 5350-5358 9 p.

  Research output: Contribution to journal › Article › peer-review
  135 Scopus citations

• Targeting Behavior of Hepatic Artery Injected Temperature Sensitive Liposomal Adriamycin on Tumor-Bearing Rats

  Zou, Y., Gu, X., Ueno, M., Yamagishi, M., Horikoshi, I., Yamashita, I. & Tazawa, K., Jan 1 1990, In: Selective Cancer Therapeutics. 6, 3, p. 119-127 9 p.

  Research output: Contribution to journal › Article › peer-review
  22 Scopus citations

• Targeting Blood Glucose Management in School Improves Glycemic Control in Children with Poorly Controlled Type 1 Diabetes Mellitus

  Nguyen, T. M., Mason, K. J., Sanders, C. G., Yazdani, P. & Heptulla, R. A., Oct 2008, In: Journal of Pediatrics. 153, 4, p. 575-578 4 p.

  Research output: Contribution to journal › Article › peer-review
  32 Scopus citations

• Targeting CDK1 promotes FLT3-activated acute myeloid leukemia differentiation through C/EBPα

  Radomska, H. S., Alberich-Jordà, M., Will, B., Gonzalez, D., Delwel, R. & Tenen, D. G., Aug 1 2012, In: Journal of Clinical Investigation. 122, 8, p. 2955-2966 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  43 Scopus citations

• Targeting Chemokine pathways in esophageal adenocarcinoma

  Shrivastava, M. S., Hussain, Z., Giricz, O., Shenoy, N., Polineni, R., Maitra, A. & Verma, A., Nov 1 2014, In: Cell Cycle. 13, 21, p. 3320-3327 8 p.

  Research output: Contribution to journal › Article › peer-review
  27 Scopus citations

• Targeting colon cancer with the novel STAT3 inhibitor bruceantinol

  Wei, N., Li, J., Fang, C., Chang, J., Xirou, V., Syrigos, N. K., Marks, B. J., Chu, E. & Schmitz, J. C., Mar 7 2019, In: Oncogene. 38, 10, p. 1676-1687 12 p.

  Research output: Contribution to journal › Article › peer-review
  44 Scopus citations

• Targeting cyclin D1, a downstream effector of INI1/hSNF5, in rhabdoid tumors

  Alarcon-Vargas, D., Zhang, Z., Agarwal, B., Challagulla, K., Mani, S. & Kalpana, G. V., Feb 2 2006, In: Oncogene. 25, 5, p. 722-734 13 p.

  Research output: Contribution to journal › Article › peer-review
  58 Scopus citations

• Targeting cyclophilin D and the mitochondrial permeability transition enhances β-cell survival and prevents diabetes in Pdx1 deficiency

  Fujimoto, K., Chen, Y., Polonsky, K. S. & Dorn, G. W., Jun 1 2010, In: Proceedings of the National Academy of Sciences of the United States of America. 107, 22, p. 10214-10219 6 p.

  Research output: Contribution to journal › Article › peer-review
  69 Scopus citations

• Targeting DDX3 in Medulloblastoma Using the Small Molecule Inhibitor RK-33

  Tantravedi, S., Vesuna, F., Winnard, P. T., Martin, A., Lim, M., Eberhart, C. G., Berlinicke, C., Raabe, E., van Diest, P. J. & Raman, V., Jan 2019, In: Translational Oncology. 12, 1, p. 96-105 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  26 Scopus citations

• Targeting eIF4A-dependent translation of KRAS signaling molecules

  Singh, K., Lin, J., Lecomte, N., Mohan, P., Gokce, A., Sanghvi, V. R., Jiang, M., Grbovic-Huezo, O., Burčul, A., Stark, S. G., Romesser, P. B., Chang, Q., Melchor, J. P., Beyer, R. K., Duggan, M., Fukase, Y., Yang, G., Ouerfelli, O., Viale, A., De Stanchina, E., & 6 othersStamford, A. W., Meinke, P. T., Rätsch, G., Leach, S. D., Ouyang, Z. & Wendel, H. G., Apr 2021, In: Cancer research. 81, 8, p. 2002-2014 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  7 Scopus citations

• Targeting estrogens and various estrogen-related receptors against non-small cell lung cancers: A perspective

  Maitra, R., Malik, P. & Mukherjee, T. K., Jan 1 2022, In: Cancers. 14, 1, 80.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  3 Scopus citations

• Targeting family functioning, acculturative stress, and sugar-sweetened beverage consumption for obesity prevention: findings from the Hispanic community children’s health study/study of Latino youth

  Figueroa, R., Isasi, C. R., Perreira, K. M., McClain, A. C., Gallo, L. C., Sotres-Alvarez, D., Delamater, A. M., Daviglus, M., Van Horn, L. & Mattei, J., Dec 1 2020, In: BMC public health. 20, 1, 1546.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  3 Scopus citations

• Targeting Glycoprotein NMB With Antibody-Drug Conjugate, Glembatumumab Vedotin, for the Treatment of Osteosarcoma

  Roth, M., Barris, D. M., Piperdi, S., Kuo, V., Everts, S., Geller, D., Houghton, P., Kolb, E. A., Hawthorne, T., Gill, J. & Gorlick, R., Jan 1 2016, In: Pediatric Blood and Cancer. 63, 1, p. 32-38 7 p.

  Research output: Contribution to journal › Article › peer-review
  44 Scopus citations

• Targeting HSP90 ameliorates nephropathy and atherosclerosis through suppression of NF-κB and STAT signaling pathways in diabetic mice

  Lazaro, I., Oguiza, A., Recio, C., Mallavia, B., Madrigal-Matute, J., Blanco, J., Egido, J., Martin-Ventura, J. L. & Gomez-Guerrero, C., Oct 2015, In: Diabetes. 64, 10, p. 3600-3613 14 p.

  Research output: Contribution to journal › Article › peer-review
  47 Scopus citations

• Targeting human papillomavirus type 16 E7 to the endosomal/lysosomal compartment enhances the antitumor immunity of DNA vaccines against murine human papillomavirus type 16 E7-expressing tumors

  Ji, H., Wang, T. L., Chen, C. H., Pai, S. I., Hung, C. F., Lin, K. Y., Kurman, R. J., Pardoll, D. M. & Wu, T. C., Nov 20 1999, In: Human Gene Therapy. 10, 17, p. 2727-2740 14 p.

  Research output: Contribution to journal › Article › peer-review
  213 Scopus citations

• Targeting hypoxic cancer stem cells (CSCs) with Doxycycline: Implications for optimizing anti-angiogenic therapy

  De Francesco, E. M., Maggiolini, M., Tanowitz, H. B., Sotgia, F. & Lisanti, M. P., 2017, In: Oncotarget. 8, 34, p. 56126-56142 17 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  37 Scopus citations

• Targeting IL-17A in multiple myeloma: A potential novel therapeutic approach in myeloma

  Prabhala, R. H., Fulciniti, M., Pelluru, D., Rashid, N., Nigroiu, A., Nanjappa, P., Pai, C., Lee, S., Prabhala, N. S., Bandi, R. L., Smith, R., Lazo-Kallanian, S. B., Valet, S., Raje, N., Gold, J. S., Richardson, P. G., Daley, J. F., Anderson, K. C., Ettenberg, S. A., Di Padova, F., & 1 othersMunshi, N. C., Feb 1 2016, In: Leukemia. 30, 2, p. 379-389 11 p.

  Research output: Contribution to journal › Article › peer-review
  54 Scopus citations

• Targeting immunophenotypic markers on leukemic stem cells: How lessons from current approaches and advances in the Leukemia stem cell (LSC) model can inform better strategies for treating acute myeloid leukemia (AML)

  Mitchell, K. & Steidl, U., Jan 2020, In: Cold Spring Harbor Perspectives in Medicine. 10, 1, a036251.

  Research output: Contribution to journal › Article › peer-review
  11 Scopus citations

• Targeting insulin inhibition as a metabolic therapy in advanced cancer: A pilot safety and feasibility dietary trial in 10 patients

  Fine, E. J., Segal-Isaacson, C. J., Feinman, R. D., Herszkopf, S., Romano, M. C., Tomuta, N., Bontempo, A. F., Negassa, A. & Sparano, J. A., Oct 2012, In: Nutrition. 28, 10, p. 1028-1035 8 p.

  Research output: Contribution to journal › Article › peer-review
  127 Scopus citations

• Targeting invadopodia-mediated breast cancer metastasis by using ABL kinase inhibitors

  Meirson, T., Genna, A., Lukic, N., Makhnii, T., Alter, J., Sharma, V. P., Wang, Y., Samson, A. O., Condeelis, J. S. & Gil-Henn, H., Apr 24 2018, In: Oncotarget. 9, 31, p. 22163-22188 26 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  26 Scopus citations

• Targeting liver tumors by administering liposomal doxorubicin into the hepatic artery

  Zou, Y., Horikoshi, I., Ueno, M., Gu, X. & Perez‐Soler, R., May 8 1992, In: International Journal of Cancer. 51, 2, p. 232-237 6 p.

  Research output: Contribution to journal › Article › peer-review
  11 Scopus citations

• Targeting lung cancer using an infectivity enhanced CXCR4-CRAd

  Zhu, Z. B., Rivera, A. A., Makhija, S. K., Lu, B., Wang, M., Izumi, M., Cerfolio, R. J., Stoff-Khalili, M. A., Zhou, F., Takayama, K., Siegal, G. P. & Curiel, D. T., Feb 2007, In: Lung Cancer. 55, 2, p. 145-156 12 p.

  Research output: Contribution to journal › Article › peer-review
  11 Scopus citations

• Targeting Mac-1-mediated leukocyte–RBC interactions uncouples the benefits for acute vaso-occlusion and chronic organ damage

  Chen, G., Chang, J., Zhang, D., Pinho, S., Jang, J. E. & Frenette, P. S., Oct 1 2016, In: Experimental Hematology. 44, 10, p. 940-946 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  11 Scopus citations

• Targeting mesothelioma using an infectivity enhanced survivin-conditionally replicative adenoviruses

  Zhu, Z. B., Makhija, S. K., Lu, B., Wang, M., Wang, S., Takayama, K., Siegal, G. P., Reynolds, P. N. & Curiel, D. T., Sep 2006, In: Journal of Thoracic Oncology. 1, 7, p. 701-711 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  22 Scopus citations

• Targeting mGlu receptors for optimization of antipsychotic activity and disease-modifying effect in schizophrenia

  Nicoletti, F., Orlando, R., Menna, L. D., Cannella, M., Notartomaso, S., Mascio, G., Iacovelli, L., Matrisciano, F., Fazio, F., Caraci, F., Copani, A., Battaglia, G. & Bruno, V., 2019, In: Frontiers in Psychiatry. 10, FEB, 49.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  28 Scopus citations

• Targeting mitochondrial structure sensitizes acute myeloid Leukemia to venetoclax treatment

  Chen, X., Glytsou, C., Zhou, H., Narang, S., Reyna, D. E., Lopez, A., Sakellaropoulos, T., Gong, Y., Kloetgen, A., Yap, Y. S., Wang, E., Gavathiotis, E., Tsirigos, A., Tibes, R. & Aifantis, I., Jul 2019, In: Cancer discovery. 9, 7, p. 890-909 20 p.

  Research output: Contribution to journal › Article › peer-review
  115 Scopus citations

• Targeting Mycobacterium tuberculosis tumor necrosis factor alpha-downregulating genes for the development of antituberculous vaccines

  Olsen, A., Chen, Y., Ji, Q., Zhu, G., De Silva, A. D., Vilchèze, C., Weisbrod, T., Li, W., Xu, J., Larsen, M., Zhang, J., Porcelli, S. A., Jacobs, W. R. & Chan, J., 2016, In: mBio. 7, 3, e01023-15.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  27 Scopus citations

• Targeting non-pulmonary vein triggers in persistent atrial fibrillation: Results from a prospective, multicentre, observational registry

  Della Rocca, D. G., Di Biase, L., Mohanty, S., Trivedi, C., Gianni, C., Romero, J., Tarantino, N., Magnocavallo, M., Bassiouny, M., Natale, V. N., Mayedo, A. Q., Macdonald, B., Lavalle, C., Murtaza, G., Akella, K., Forleo, G. B., Al-Ahmad, A., Burkhardt, J. D., Gallinghouse, G. J., Sanchez, J. E., & 4 othersHorton, R. P., Viles-Gonzalez, J. F., Lakkireddy, D. & Natale, A., Dec 1 2021, In: Europace. 23, 12, p. 1939-1949 11 p.

  Research output: Contribution to journal › Article › peer-review
  7 Scopus citations

• Targeting of a conditionally replicative adenovirus agent to human squamous cell carcinomas of the head and neck

  Zhu, Z. B., Mathis, J. M., Makhija, S. K., Lu, B., Wang, M., Ji, S., Rivera, A. A., Rosenthal, E. L., Siegal, G. P. & Curiel, D. T., Nov 2007, In: International journal of oncology. 31, 5, p. 1213-1222 10 p.

  Research output: Contribution to journal › Article › peer-review
  13 Scopus citations

• Targeting of cre to the Foxg1 (BF-1) locus mediates loxP recombination in the telencephalon and other developing head structures

  Hébert, J. M. & McConnell, S. K., Jun 15 2000, In: Developmental Biology. 222, 2, p. 296-306 11 p.

  Research output: Contribution to journal › Article › peer-review
  432 Scopus citations

• Targeting of rough endoplasmic reticulum membrane proteins and ribosomes in invertebrate neurons

  Rolls, M. M., Hall, D. H., Victor, M., Stelzer, E. H. K. & Rapoport, T. A., 2002, In: Molecular biology of the cell. 13, 5, p. 1778-1791 14 p.

  Research output: Contribution to journal › Article › peer-review
  127 Scopus citations

• Targeting of the FYVE domain to endosomal membranes is regulated by a histidine switch

  Lee, S. A., Eyeson, R., Cheever, M. L., Geng, J., Verkhusha, V. V., Burd, C., Overduin, M. & Kutateladze, T. G., Sep 13 2005, In: Proceedings of the National Academy of Sciences of the United States of America. 102, 37, p. 13052-13057 6 p.

  Research output: Contribution to journal › Article › peer-review
  84 Scopus citations

• Targeting of the GTPase Irgm1 to the phagosomal membrane via PtdIns(3,4)P₂ and PtdIns(3,4,5)P₃ promotes immunity to mycobacteria

  Tiwari, S., Choi, H. P., Matsuzawa, T., Pypaert, M. & MacMicking, J. D., 2009, In: Nature Immunology. 10, 8, p. 907-917 11 p.

  Research output: Contribution to journal › Article › peer-review
  96 Scopus citations

• Targeting PBK/TOPK decreases growth and survival of glioma initiating cells in vitro and attenuates tumor growth in vivo

  Joel, M., Mughal, A. A., Grieg, Z., Murrell, W., Palmero, S., Mikkelsen, B., Fjerdingstad, H. B., Sandberg, C. J., Behnan, J., Glover, J. C., Langmoen, I. A. & Stangeland, B., Jun 17 2015, In: Molecular Cancer. 14, 1, 121.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  66 Scopus citations

• Targeting pediatric pedestrian injury prevention efforts: Teasing the information through spatial analysis

  Statter, M., Schuble, T., Harris-Rosado, M., Liu, D. & Quinlan, K., Nov 1 2011, In: Journal of Trauma - Injury, Infection and Critical Care. 71, 5 SUPPL. 2, p. S511-S516

  Research output: Contribution to journal › Article › peer-review
  21 Scopus citations

• Targeting physical activity interventions for adults: When should intervention occur?

  Holliday, K. M., Lin, D. Y., Chakladar, S., Castañeda, S. F., Daviglus, M. L., Evenson, K. R., Marquez, D. X., Qi, Q., Shay, C. M., Sotres-Alvarez, D., Vidot, D. C., Zeng, D. & Avery, C. L., Apr 1 2017, In: Preventive Medicine. 97, p. 13-18 6 p.

  Research output: Contribution to journal › Article › peer-review
  3 Scopus citations

• Targeting plasmodium falciparum purine salvage enzymes: A look at structure-based drug development

  Donaldson, T. & Kim, K., Jan 1 2010, In: Infectious Disorders - Drug Targets. 10, 3, p. 191-199 9 p.

  Research output: Contribution to journal › Article › peer-review
  13 Scopus citations

• Targeting protein translation in human non-small cell lung cancer via combined MEK and mammalian target of rapamycin suppression

  Legrier, M. E., Yang, C. P. H., Yan, H. G., Lopez-Barcons, L., Keller, S. M., Pérez-Soler, R., Horwitz, S. B. & McDaid, H. M., Dec 1 2007, In: Cancer research. 67, 23, p. 11300-11308 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  79 Scopus citations

• Targeting Rejection: Analysis of Specimen Acceptability and Rejection, and Framework for Identifying Interventions in a Single Tertiary Healthcare Facility

  Rooper, L., Carter, J., Hargrove, J., Hoffmann, S. & Riedel, S., May 2017, In: Journal of Clinical Laboratory Analysis. 31, 3, e22060.

  Research output: Contribution to journal › Article › peer-review
  13 Scopus citations

• Targeting retinoic acid receptor alpha-corepressor interaction activates chaperone-mediated autophagy and protects against retinal degeneration

  Gomez-Sintes, R., Xin, Q., Jimenez-Loygorri, J. I., McCabe, M., Diaz, A., Garner, T. P., Cotto-Rios, X. M., Wu, Y., Dong, S., Reynolds, C. A., Patel, B., de la Villa, P., Macian, F., Boya, P., Gavathiotis, E. & Cuervo, A. M., Dec 2022, In: Nature communications. 13, 1, 4220.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  3 Scopus citations

• Targeting senescence

  Serrano, M. & Barzilai, N., Aug 1 2018, In: Nature Medicine. 24, 8, p. 1092-1094 3 p.

  Research output: Contribution to journal › Article › peer-review
  14 Scopus citations

• Targeting STING pathways for the treatment of cancer

  Gravekamp, C. & Chandra, D., Dec 2 2015, In: OncoImmunology. 4, 12

  Research output: Contribution to journal › Article › peer-review

  Open Access
  12 Scopus citations

• Targeting TACE-dependent EGFR ligand shedding in breast cancer

  Kenny, P. A. & Bissell, M. J., Feb 1 2007, In: Journal of Clinical Investigation. 117, 2, p. 337-345 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  224 Scopus citations

• Targeting Technology in Underserved Adults With Type 1 Diabetes: Effect of Diabetes Practice Transformations on Improving Equity in CGM Prescribing Behaviors

  Mathias, P., Mahali, L. P. & Agarwal, S., Oct 2022, In: Diabetes care. 45, 10, p. 2231-2237 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Targeting the anterior superior iliac spine yields significantly longer bone marrow cores

  Reed, L., Attarian, S., Pendurti, G., Singh, A. P., Budhathoki, A., Abi-Aad, S., Shah, U. A., Kim, S., Bachiashvili, K., Moon, J. Y., Kim, M., Elrafei, T., Alexis, K., Strakhan, M., Li, W. & Friedman, E., Feb 1 2018, In: Journal of Clinical Pathology. 71, 2, p. 172-173 2 p.

  Research output: Contribution to journal › Article › peer-review
  4 Scopus citations

• Targeting the Aryl Hydrocarbon Receptor with Microbial Metabolite Mimics Alleviates Experimental Colitis in Mice

  Grycová, A., Joo, H., Maier, V., Illés, P., Vyhlídalová, B., Poulíková, K., Sládeková, L., Nádvorník, P., Vrzal, R., Zemánková, L., Pečinková, P., Poruba, M., Zapletalová, I., Večeřa, R., Anzenbacher, P., Ehrmann, J., Ondra, P., Jung, J. W., Mani, S. & Dvořák, Z., 2022, (Accepted/In press) In: Journal of Medicinal Chemistry.

  Research output: Contribution to journal › Article › peer-review
  4 Scopus citations

• Targeting the CaMKII/ERK interaction in the heart prevents cardiac hypertrophy

  Cipolletta, E., Rusciano, M. R., Maione, A. S., Santulli, G., Sorriento, D., Del Giudice, C., Ciccarelli, M., Franco, A., Crola, C., Campiglia, P., Sala, M., Gomez-Monterrey, I., De Luca, N., Trimarco, B., Iaccarino, G. & Illario, M., Jun 25 2015, In: PloS one. 10, 6, e0130477.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  47 Scopus citations

• Targeting the chemokines in cardiac repair

  Cavalera, M. & Frangogiannis, N. G., 2014, In: Current pharmaceutical design. 20, 12, p. 1971-1979 9 p.

  Research output: Contribution to journal › Article › peer-review
  49 Scopus citations

• Targeting the MYCN–PARP–DNA damage response pathway in neuroendocrine prostate cancer

  Zhang, W., Liu, B., Wu, W., Li, L., Broom, B. M., Basourakos, S. P., Korentzelos, D., Luan, Y., Wang, J., Yang, G., Park, S., Azad, A. K., Cao, X., Kim, J., Corn, P. G., Logothetis, C. J., Aparicio, A. M., Chinnaiyan, A. M., Navone, N., Troncoso, P., & 1 othersThompson, T. C., Feb 1 2018, In: Clinical Cancer Research. 24, 3, p. 696-707 12 p.

  Research output: Contribution to journal › Article › peer-review
  55 Scopus citations