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Targeting a novel Plasmodium falciparum purine recycling pathway with specific immucillins
Ting, L. M., Shi, W., Lewandowicz, A., Singh, V., Mwakingwe, A., Birck, M. R., Taylor Ringia, E. A., Bench, G., Madrid, D. C., Tyler, P. C., Evans, G. B., Furneaux, R. H., Schramm, V. L. & Kim, K., Mar 11 2005, In: Journal of Biological Chemistry. 280, 10, p. 9547-9554 8 p.Research output: Contribution to journal › Article › peer-review
111 Scopus citations -
Targeting Bcl-2 family members with the BH3 mimetic AT-101 markedly enhances the therapeutic effects of chemotherapeutic agents in in vitro and in vivo models of B-cell lymphoma
Paoluzzi, L., Gonen, M., Gardner, J. R., Mastrella, J., Yang, D., Holmlund, J., Sorensen, M., Leopold, L., Manova, K., Marcucci, G., Heaney, M. L. & O'Connor, O. A., Jun 1 2008, In: Blood. 111, 11, p. 5350-5358 9 p.Research output: Contribution to journal › Article › peer-review
135 Scopus citations -
Targeting Behavior of Hepatic Artery Injected Temperature Sensitive Liposomal Adriamycin on Tumor-Bearing Rats
Zou, Y., Gu, X., Ueno, M., Yamagishi, M., Horikoshi, I., Yamashita, I. & Tazawa, K., Jan 1 1990, In: Selective Cancer Therapeutics. 6, 3, p. 119-127 9 p.Research output: Contribution to journal › Article › peer-review
22 Scopus citations -
Targeting Blood Glucose Management in School Improves Glycemic Control in Children with Poorly Controlled Type 1 Diabetes Mellitus
Nguyen, T. M., Mason, K. J., Sanders, C. G., Yazdani, P. & Heptulla, R. A., Oct 2008, In: Journal of Pediatrics. 153, 4, p. 575-578 4 p.Research output: Contribution to journal › Article › peer-review
32 Scopus citations -
Targeting CDK1 promotes FLT3-activated acute myeloid leukemia differentiation through C/EBPα
Radomska, H. S., Alberich-Jordà, M., Will, B., Gonzalez, D., Delwel, R. & Tenen, D. G., Aug 1 2012, In: Journal of Clinical Investigation. 122, 8, p. 2955-2966 12 p.Research output: Contribution to journal › Article › peer-review
Open Access43 Scopus citations -
Targeting Chemokine pathways in esophageal adenocarcinoma
Shrivastava, M. S., Hussain, Z., Giricz, O., Shenoy, N., Polineni, R., Maitra, A. & Verma, A., Nov 1 2014, In: Cell Cycle. 13, 21, p. 3320-3327 8 p.Research output: Contribution to journal › Article › peer-review
27 Scopus citations -
Targeting colon cancer with the novel STAT3 inhibitor bruceantinol
Wei, N., Li, J., Fang, C., Chang, J., Xirou, V., Syrigos, N. K., Marks, B. J., Chu, E. & Schmitz, J. C., Mar 7 2019, In: Oncogene. 38, 10, p. 1676-1687 12 p.Research output: Contribution to journal › Article › peer-review
44 Scopus citations -
Targeting cyclin D1, a downstream effector of INI1/hSNF5, in rhabdoid tumors
Alarcon-Vargas, D., Zhang, Z., Agarwal, B., Challagulla, K., Mani, S. & Kalpana, G. V., Feb 2 2006, In: Oncogene. 25, 5, p. 722-734 13 p.Research output: Contribution to journal › Article › peer-review
58 Scopus citations -
Targeting cyclophilin D and the mitochondrial permeability transition enhances β-cell survival and prevents diabetes in Pdx1 deficiency
Fujimoto, K., Chen, Y., Polonsky, K. S. & Dorn, G. W., Jun 1 2010, In: Proceedings of the National Academy of Sciences of the United States of America. 107, 22, p. 10214-10219 6 p.Research output: Contribution to journal › Article › peer-review
69 Scopus citations -
Targeting DDX3 in Medulloblastoma Using the Small Molecule Inhibitor RK-33
Tantravedi, S., Vesuna, F., Winnard, P. T., Martin, A., Lim, M., Eberhart, C. G., Berlinicke, C., Raabe, E., van Diest, P. J. & Raman, V., Jan 2019, In: Translational Oncology. 12, 1, p. 96-105 10 p.Research output: Contribution to journal › Article › peer-review
Open Access26 Scopus citations -
Targeting eIF4A-dependent translation of KRAS signaling molecules
Singh, K., Lin, J., Lecomte, N., Mohan, P., Gokce, A., Sanghvi, V. R., Jiang, M., Grbovic-Huezo, O., Burčul, A., Stark, S. G., Romesser, P. B., Chang, Q., Melchor, J. P., Beyer, R. K., Duggan, M., Fukase, Y., Yang, G., Ouerfelli, O., Viale, A., De Stanchina, E., & 6 others , Apr 2021, In: Cancer research. 81, 8, p. 2002-2014 13 p.Research output: Contribution to journal › Article › peer-review
Open Access7 Scopus citations -
Targeting estrogens and various estrogen-related receptors against non-small cell lung cancers: A perspective
Maitra, R., Malik, P. & Mukherjee, T. K., Jan 1 2022, In: Cancers. 14, 1, 80.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Targeting family functioning, acculturative stress, and sugar-sweetened beverage consumption for obesity prevention: findings from the Hispanic community children’s health study/study of Latino youth
Figueroa, R., Isasi, C. R., Perreira, K. M., McClain, A. C., Gallo, L. C., Sotres-Alvarez, D., Delamater, A. M., Daviglus, M., Van Horn, L. & Mattei, J., Dec 1 2020, In: BMC public health. 20, 1, 1546.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Targeting Glycoprotein NMB With Antibody-Drug Conjugate, Glembatumumab Vedotin, for the Treatment of Osteosarcoma
Roth, M., Barris, D. M., Piperdi, S., Kuo, V., Everts, S., Geller, D., Houghton, P., Kolb, E. A., Hawthorne, T., Gill, J. & Gorlick, R., Jan 1 2016, In: Pediatric Blood and Cancer. 63, 1, p. 32-38 7 p.Research output: Contribution to journal › Article › peer-review
44 Scopus citations -
Targeting HSP90 ameliorates nephropathy and atherosclerosis through suppression of NF-κB and STAT signaling pathways in diabetic mice
Lazaro, I., Oguiza, A., Recio, C., Mallavia, B., Madrigal-Matute, J., Blanco, J., Egido, J., Martin-Ventura, J. L. & Gomez-Guerrero, C., Oct 2015, In: Diabetes. 64, 10, p. 3600-3613 14 p.Research output: Contribution to journal › Article › peer-review
47 Scopus citations -
Targeting human papillomavirus type 16 E7 to the endosomal/lysosomal compartment enhances the antitumor immunity of DNA vaccines against murine human papillomavirus type 16 E7-expressing tumors
Ji, H., Wang, T. L., Chen, C. H., Pai, S. I., Hung, C. F., Lin, K. Y., Kurman, R. J., Pardoll, D. M. & Wu, T. C., Nov 20 1999, In: Human Gene Therapy. 10, 17, p. 2727-2740 14 p.Research output: Contribution to journal › Article › peer-review
213 Scopus citations -
Targeting hypoxic cancer stem cells (CSCs) with Doxycycline: Implications for optimizing anti-angiogenic therapy
De Francesco, E. M., Maggiolini, M., Tanowitz, H. B., Sotgia, F. & Lisanti, M. P., 2017, In: Oncotarget. 8, 34, p. 56126-56142 17 p.Research output: Contribution to journal › Article › peer-review
Open Access37 Scopus citations -
Targeting IL-17A in multiple myeloma: A potential novel therapeutic approach in myeloma
Prabhala, R. H., Fulciniti, M., Pelluru, D., Rashid, N., Nigroiu, A., Nanjappa, P., Pai, C., Lee, S., Prabhala, N. S., Bandi, R. L., Smith, R., Lazo-Kallanian, S. B., Valet, S., Raje, N., Gold, J. S., Richardson, P. G., Daley, J. F., Anderson, K. C., Ettenberg, S. A., Di Padova, F., & 1 others , Feb 1 2016, In: Leukemia. 30, 2, p. 379-389 11 p.Research output: Contribution to journal › Article › peer-review
54 Scopus citations -
Targeting immunophenotypic markers on leukemic stem cells: How lessons from current approaches and advances in the Leukemia stem cell (LSC) model can inform better strategies for treating acute myeloid leukemia (AML)
Mitchell, K. & Steidl, U., Jan 2020, In: Cold Spring Harbor Perspectives in Medicine. 10, 1, a036251.Research output: Contribution to journal › Article › peer-review
11 Scopus citations -
Targeting insulin inhibition as a metabolic therapy in advanced cancer: A pilot safety and feasibility dietary trial in 10 patients
Fine, E. J., Segal-Isaacson, C. J., Feinman, R. D., Herszkopf, S., Romano, M. C., Tomuta, N., Bontempo, A. F., Negassa, A. & Sparano, J. A., Oct 2012, In: Nutrition. 28, 10, p. 1028-1035 8 p.Research output: Contribution to journal › Article › peer-review
127 Scopus citations -
Targeting invadopodia-mediated breast cancer metastasis by using ABL kinase inhibitors
Meirson, T., Genna, A., Lukic, N., Makhnii, T., Alter, J., Sharma, V. P., Wang, Y., Samson, A. O., Condeelis, J. S. & Gil-Henn, H., Apr 24 2018, In: Oncotarget. 9, 31, p. 22163-22188 26 p.Research output: Contribution to journal › Article › peer-review
Open Access26 Scopus citations -
Targeting liver tumors by administering liposomal doxorubicin into the hepatic artery
Zou, Y., Horikoshi, I., Ueno, M., Gu, X. & Perez‐Soler, R., May 8 1992, In: International Journal of Cancer. 51, 2, p. 232-237 6 p.Research output: Contribution to journal › Article › peer-review
11 Scopus citations -
Targeting lung cancer using an infectivity enhanced CXCR4-CRAd
Zhu, Z. B., Rivera, A. A., Makhija, S. K., Lu, B., Wang, M., Izumi, M., Cerfolio, R. J., Stoff-Khalili, M. A., Zhou, F., Takayama, K., Siegal, G. P. & Curiel, D. T., Feb 2007, In: Lung Cancer. 55, 2, p. 145-156 12 p.Research output: Contribution to journal › Article › peer-review
11 Scopus citations -
Targeting Mac-1-mediated leukocyte–RBC interactions uncouples the benefits for acute vaso-occlusion and chronic organ damage
Chen, G., Chang, J., Zhang, D., Pinho, S., Jang, J. E. & Frenette, P. S., Oct 1 2016, In: Experimental Hematology. 44, 10, p. 940-946 7 p.Research output: Contribution to journal › Article › peer-review
Open Access11 Scopus citations -
Targeting mesothelioma using an infectivity enhanced survivin-conditionally replicative adenoviruses
Zhu, Z. B., Makhija, S. K., Lu, B., Wang, M., Wang, S., Takayama, K., Siegal, G. P., Reynolds, P. N. & Curiel, D. T., Sep 2006, In: Journal of Thoracic Oncology. 1, 7, p. 701-711 11 p.Research output: Contribution to journal › Article › peer-review
Open Access22 Scopus citations -
Targeting mGlu receptors for optimization of antipsychotic activity and disease-modifying effect in schizophrenia
Nicoletti, F., Orlando, R., Menna, L. D., Cannella, M., Notartomaso, S., Mascio, G., Iacovelli, L., Matrisciano, F., Fazio, F., Caraci, F., Copani, A., Battaglia, G. & Bruno, V., 2019, In: Frontiers in Psychiatry. 10, FEB, 49.Research output: Contribution to journal › Article › peer-review
Open Access28 Scopus citations -
Targeting mitochondrial structure sensitizes acute myeloid Leukemia to venetoclax treatment
Chen, X., Glytsou, C., Zhou, H., Narang, S., Reyna, D. E., Lopez, A., Sakellaropoulos, T., Gong, Y., Kloetgen, A., Yap, Y. S., Wang, E., Gavathiotis, E., Tsirigos, A., Tibes, R. & Aifantis, I., Jul 2019, In: Cancer discovery. 9, 7, p. 890-909 20 p.Research output: Contribution to journal › Article › peer-review
115 Scopus citations -
Targeting Mycobacterium tuberculosis tumor necrosis factor alpha-downregulating genes for the development of antituberculous vaccines
Olsen, A., Chen, Y., Ji, Q., Zhu, G., De Silva, A. D., Vilchèze, C., Weisbrod, T., Li, W., Xu, J., Larsen, M., Zhang, J., Porcelli, S. A., Jacobs, W. R. & Chan, J., 2016, In: mBio. 7, 3, e01023-15.Research output: Contribution to journal › Article › peer-review
Open Access27 Scopus citations -
Targeting non-pulmonary vein triggers in persistent atrial fibrillation: Results from a prospective, multicentre, observational registry
Della Rocca, D. G., Di Biase, L., Mohanty, S., Trivedi, C., Gianni, C., Romero, J., Tarantino, N., Magnocavallo, M., Bassiouny, M., Natale, V. N., Mayedo, A. Q., Macdonald, B., Lavalle, C., Murtaza, G., Akella, K., Forleo, G. B., Al-Ahmad, A., Burkhardt, J. D., Gallinghouse, G. J., Sanchez, J. E., & 4 others , Dec 1 2021, In: Europace. 23, 12, p. 1939-1949 11 p.Research output: Contribution to journal › Article › peer-review
7 Scopus citations -
Targeting of a conditionally replicative adenovirus agent to human squamous cell carcinomas of the head and neck
Zhu, Z. B., Mathis, J. M., Makhija, S. K., Lu, B., Wang, M., Ji, S., Rivera, A. A., Rosenthal, E. L., Siegal, G. P. & Curiel, D. T., Nov 2007, In: International journal of oncology. 31, 5, p. 1213-1222 10 p.Research output: Contribution to journal › Article › peer-review
13 Scopus citations -
Targeting of cre to the Foxg1 (BF-1) locus mediates loxP recombination in the telencephalon and other developing head structures
Hébert, J. M. & McConnell, S. K., Jun 15 2000, In: Developmental Biology. 222, 2, p. 296-306 11 p.Research output: Contribution to journal › Article › peer-review
432 Scopus citations -
Targeting of rough endoplasmic reticulum membrane proteins and ribosomes in invertebrate neurons
Rolls, M. M., Hall, D. H., Victor, M., Stelzer, E. H. K. & Rapoport, T. A., 2002, In: Molecular biology of the cell. 13, 5, p. 1778-1791 14 p.Research output: Contribution to journal › Article › peer-review
127 Scopus citations -
Targeting of the FYVE domain to endosomal membranes is regulated by a histidine switch
Lee, S. A., Eyeson, R., Cheever, M. L., Geng, J., Verkhusha, V. V., Burd, C., Overduin, M. & Kutateladze, T. G., Sep 13 2005, In: Proceedings of the National Academy of Sciences of the United States of America. 102, 37, p. 13052-13057 6 p.Research output: Contribution to journal › Article › peer-review
84 Scopus citations -
Targeting of the GTPase Irgm1 to the phagosomal membrane via PtdIns(3,4)P2 and PtdIns(3,4,5)P3 promotes immunity to mycobacteria
Tiwari, S., Choi, H. P., Matsuzawa, T., Pypaert, M. & MacMicking, J. D., 2009, In: Nature Immunology. 10, 8, p. 907-917 11 p.Research output: Contribution to journal › Article › peer-review
96 Scopus citations -
Targeting PBK/TOPK decreases growth and survival of glioma initiating cells in vitro and attenuates tumor growth in vivo
Joel, M., Mughal, A. A., Grieg, Z., Murrell, W., Palmero, S., Mikkelsen, B., Fjerdingstad, H. B., Sandberg, C. J., Behnan, J., Glover, J. C., Langmoen, I. A. & Stangeland, B., Jun 17 2015, In: Molecular Cancer. 14, 1, 121.Research output: Contribution to journal › Article › peer-review
Open Access66 Scopus citations -
Targeting pediatric pedestrian injury prevention efforts: Teasing the information through spatial analysis
Statter, M., Schuble, T., Harris-Rosado, M., Liu, D. & Quinlan, K., Nov 1 2011, In: Journal of Trauma - Injury, Infection and Critical Care. 71, 5 SUPPL. 2, p. S511-S516Research output: Contribution to journal › Article › peer-review
21 Scopus citations -
Targeting physical activity interventions for adults: When should intervention occur?
Holliday, K. M., Lin, D. Y., Chakladar, S., Castañeda, S. F., Daviglus, M. L., Evenson, K. R., Marquez, D. X., Qi, Q., Shay, C. M., Sotres-Alvarez, D., Vidot, D. C., Zeng, D. & Avery, C. L., Apr 1 2017, In: Preventive Medicine. 97, p. 13-18 6 p.Research output: Contribution to journal › Article › peer-review
3 Scopus citations -
Targeting plasmodium falciparum purine salvage enzymes: A look at structure-based drug development
Donaldson, T. & Kim, K., Jan 1 2010, In: Infectious Disorders - Drug Targets. 10, 3, p. 191-199 9 p.Research output: Contribution to journal › Article › peer-review
13 Scopus citations -
Targeting protein translation in human non-small cell lung cancer via combined MEK and mammalian target of rapamycin suppression
Legrier, M. E., Yang, C. P. H., Yan, H. G., Lopez-Barcons, L., Keller, S. M., Pérez-Soler, R., Horwitz, S. B. & McDaid, H. M., Dec 1 2007, In: Cancer research. 67, 23, p. 11300-11308 9 p.Research output: Contribution to journal › Article › peer-review
Open Access79 Scopus citations -
Targeting Rejection: Analysis of Specimen Acceptability and Rejection, and Framework for Identifying Interventions in a Single Tertiary Healthcare Facility
Rooper, L., Carter, J., Hargrove, J., Hoffmann, S. & Riedel, S., May 2017, In: Journal of Clinical Laboratory Analysis. 31, 3, e22060.Research output: Contribution to journal › Article › peer-review
13 Scopus citations -
Targeting retinoic acid receptor alpha-corepressor interaction activates chaperone-mediated autophagy and protects against retinal degeneration
Gomez-Sintes, R., Xin, Q., Jimenez-Loygorri, J. I., McCabe, M., Diaz, A., Garner, T. P., Cotto-Rios, X. M., Wu, Y., Dong, S., Reynolds, C. A., Patel, B., de la Villa, P., Macian, F., Boya, P., Gavathiotis, E. & Cuervo, A. M., Dec 2022, In: Nature communications. 13, 1, 4220.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Targeting senescence
Serrano, M. & Barzilai, N., Aug 1 2018, In: Nature Medicine. 24, 8, p. 1092-1094 3 p.Research output: Contribution to journal › Article › peer-review
14 Scopus citations -
Targeting STING pathways for the treatment of cancer
Gravekamp, C. & Chandra, D., Dec 2 2015, In: OncoImmunology. 4, 12Research output: Contribution to journal › Article › peer-review
Open Access12 Scopus citations -
Targeting TACE-dependent EGFR ligand shedding in breast cancer
Kenny, P. A. & Bissell, M. J., Feb 1 2007, In: Journal of Clinical Investigation. 117, 2, p. 337-345 9 p.Research output: Contribution to journal › Article › peer-review
Open Access224 Scopus citations -
Targeting Technology in Underserved Adults With Type 1 Diabetes: Effect of Diabetes Practice Transformations on Improving Equity in CGM Prescribing Behaviors
Mathias, P., Mahali, L. P. & Agarwal, S., Oct 2022, In: Diabetes care. 45, 10, p. 2231-2237 7 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Targeting the anterior superior iliac spine yields significantly longer bone marrow cores
Reed, L., Attarian, S., Pendurti, G., Singh, A. P., Budhathoki, A., Abi-Aad, S., Shah, U. A., Kim, S., Bachiashvili, K., Moon, J. Y., Kim, M., Elrafei, T., Alexis, K., Strakhan, M., Li, W. & Friedman, E., Feb 1 2018, In: Journal of Clinical Pathology. 71, 2, p. 172-173 2 p.Research output: Contribution to journal › Article › peer-review
4 Scopus citations -
Targeting the Aryl Hydrocarbon Receptor with Microbial Metabolite Mimics Alleviates Experimental Colitis in Mice
Grycová, A., Joo, H., Maier, V., Illés, P., Vyhlídalová, B., Poulíková, K., Sládeková, L., Nádvorník, P., Vrzal, R., Zemánková, L., Pečinková, P., Poruba, M., Zapletalová, I., Večeřa, R., Anzenbacher, P., Ehrmann, J., Ondra, P., Jung, J. W., Mani, S. & Dvořák, Z., 2022, (Accepted/In press) In: Journal of Medicinal Chemistry.Research output: Contribution to journal › Article › peer-review
4 Scopus citations -
Targeting the CaMKII/ERK interaction in the heart prevents cardiac hypertrophy
Cipolletta, E., Rusciano, M. R., Maione, A. S., Santulli, G., Sorriento, D., Del Giudice, C., Ciccarelli, M., Franco, A., Crola, C., Campiglia, P., Sala, M., Gomez-Monterrey, I., De Luca, N., Trimarco, B., Iaccarino, G. & Illario, M., Jun 25 2015, In: PloS one. 10, 6, e0130477.Research output: Contribution to journal › Article › peer-review
Open Access47 Scopus citations -
Targeting the chemokines in cardiac repair
Cavalera, M. & Frangogiannis, N. G., 2014, In: Current pharmaceutical design. 20, 12, p. 1971-1979 9 p.Research output: Contribution to journal › Article › peer-review
49 Scopus citations -
Targeting the MYCN–PARP–DNA damage response pathway in neuroendocrine prostate cancer
Zhang, W., Liu, B., Wu, W., Li, L., Broom, B. M., Basourakos, S. P., Korentzelos, D., Luan, Y., Wang, J., Yang, G., Park, S., Azad, A. K., Cao, X., Kim, J., Corn, P. G., Logothetis, C. J., Aparicio, A. M., Chinnaiyan, A. M., Navone, N., Troncoso, P., & 1 others , Feb 1 2018, In: Clinical Cancer Research. 24, 3, p. 696-707 12 p.Research output: Contribution to journal › Article › peer-review
55 Scopus citations