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  Signaling by the engulfment receptor draper: A screen in drosophila melanogaster implicates cytoskeletal regulators, Jun N-terminal Kinase, and Yorkie

  Fullard, J. F. & Baker, N. E., Jan 1 2015, In: Genetics. 199, 1, p. 117-134 18 p.

  Research output: Contribution to journal › Article › peer-review
  8 Scopus citations

• Signaling molecules involved in coupling growth hormone receptor to mitogen-activated protein kinase activation

  Vanderkuur, J. A., Butch, E. R., Waters, S. B., Pessin, J. E., Guan, K. L. & Carter-Su, C., 1997, In: Endocrinology. 138, 10, p. 4301-4307 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  102 Scopus citations

• Signal integration and the specificity of insulin action

  Kanzaki, M. & Pessin, J. E., 2001, In: Cell Biochemistry and Biophysics. 35, 2, p. 191-209 19 p.

  Research output: Contribution to journal › Article › peer-review
  29 Scopus citations

• Signalling thresholds and negative B-cell selection in acute lymphoblastic leukaemia

  Chen, Z., Shojaee, S., Buchner, M., Geng, H., Lee, J. W., Klemm, L., Titz, B., Graeber, T. G., Park, E., Tan, Y. X., Satterthwaite, A., Paietta, E., Hunger, S. P., Willman, C. L., Melnick, A., Loh, M. L., Jung, J. U., Coligan, J. E., Bolland, S., Mak, T. W., & 6 othersLimnander, A., Jumaa, H., Reth, M., Weiss, A., Lowell, C. A. & Müschen, M., May 21 2015, In: Nature. 521, 7552, p. 357-361 5 p.

  Research output: Contribution to journal › Article › peer-review
  90 Scopus citations

• Signal processing times in bacterial chemotaxis

  Segall, J. E., Manson, M. D. & Berg, H. C., 1982, In: Nature. 296, 5860, p. 855-857 3 p.

  Research output: Contribution to journal › Article › peer-review
  114 Scopus citations

• Signal regulatory protein α (SIRPα)⁺ cells in the adaptive response to ESAT-6/CFP-10 protein of tuberculous mycobacteria

  Waters, W. R., Palmer, M. V., Nonnecke, B. J., Thacker, T. C., Estes, D. M., Larsen, M. H., Jacobs, W. R., Andersen, P., McNair, J., Minion, F. C., Lyaschenko, K. P., Hewinson, R. G., Vordermeier, H. M. & Sacco, R. E., Jul 29 2009, In: PloS one. 4, 7, e6414.

  Research output: Contribution to journal › Article › peer-review
  7 Scopus citations

• Signal requirements for lymphocyte activation: Role of a T-cell growth factor produced by guinea pig peritoneal exudate lymphocytes

  Weinblatt, A. C., Oppenheim, J. J. & Rosenstreich, D. L., Apr 1982, In: Cellular Immunology. 68, 2, p. 332-342 11 p.

  Research output: Contribution to journal › Article › peer-review
  6 Scopus citations

• Signal requirements for T lymphocyte activation. I. Replacement of macrophage function with phorbol myristic acetate

  Rosenstreich, D. L. & Mizel, S. B., Dec 1 1979, In: Journal of Immunology. 123, 4, p. 1749-1754 6 p.

  Research output: Contribution to journal › Article › peer-review
  91 Scopus citations

• Signals from the sympathetic nervous system regulate hematopoietic stem cell egress from bone marrow

  Katayama, Y., Battista, M., Kao, W. M., Hidalgo, A., Peired, A. J., Thomas, S. A. & Frenette, P. S., Jan 27 2006, In: Cell. 124, 2, p. 407-421 15 p.

  Research output: Contribution to journal › Article › peer-review
  989 Scopus citations

• Signals transduced via insulin-like growth factor I receptor (IGF_R) mediate resistance to retinoic acid-induced cell growth arrest in a human neuroblastoma cell line

  Matsumoto, K., Lucarelli, E., Minniti, C., Gaetano, C. & Thiele, C. J., Dec 1 1994, In: Cell Death and Differentiation. 1, 1, p. 49-58 10 p.

  Research output: Contribution to journal › Article › peer-review
  12 Scopus citations

• Signal transducer and activator of transcription (Stat) 5b-mediated inhibition of insulin-like growth factor binding protein-1 gene transcription: A mechanism for repression of gene expression by growth hormone

  Ono, M., Chia, D. J., Merino-Martinez, R., Flores-Morales, A., Unterman, T. G. & Rotwein, P., Jun 2007, In: Molecular Endocrinology. 21, 6, p. 1443-1457 15 p.

  Research output: Contribution to journal › Article › peer-review
  31 Scopus citations

• Signal transducer and activator of transcription-3 serine phosphorylation by insulin is mediated by a Ras/Raf/MEK-dependent pathway

  Ceresa, B. P., Horvath, C. M. & Pessin, J. E., 1997, In: Endocrinology. 138, 10, p. 4131-4137 7 p.

  Research output: Contribution to journal › Article › peer-review
  58 Scopus citations

• Signal transduction by platelet adenylate cyclase: Alterations in depressed patients may reflect impairment in the coordinated integration of cellular signals (coincidence detection)

  Mooney, J. J., Samson, J. A., McHale, N. L., Colodzin, R., Alpert, J., Koutsos, M. & Schildkraut, J. J., Apr 15 1998, In: Biological Psychiatry. 43, 8, p. 574-583 10 p.

  Research output: Contribution to journal › Article › peer-review
  21 Scopus citations

• Signal Transduction Events Associated with Exocytosis in Ciliates

  SATIR, BIRGIT. H., Jul 1989, In: The Journal of Protozoology. 36, 4, p. 382-389 8 p.

  Research output: Contribution to journal › Article › peer-review
  21 Scopus citations

• Signatures of breast cancer metastasis at a glance

  Karagiannis, G. S., Goswami, S., Jones, J. G., Oktay, M. H. & Condeelis, J. S., May 1 2016, In: Journal of cell science. 129, 9, p. 1751-1758 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  39 Scopus citations

• Signet ring cell colorectal carcinoma: A distinct subset of mucin-poor microsatellite-stable signet ring cell carcinoma associated with dismal prognosis

  Hartman, D. J., Nikiforova, M. N., Chang, D. T., Chu, E., Bahary, N., Brand, R. E., Zureikat, A. H., Zeh, H. J., Choudry, H. & Pai, R. K., Jul 2013, In: American Journal of Surgical Pathology. 37, 7, p. 969-977 9 p.

  Research output: Contribution to journal › Article › peer-review
  36 Scopus citations

• Signet-ring cell lymphoma: clinicopathologic, immunohistochemical, and fluorescence in situ hybridization studies of 7 cases

  Zhang, S., Sun, J., Fang, Y., Nassiri, M., Liu, L., Zhou, J., Stohler, R., Choi, H. & Vance, G. H., Feb 1 2017, In: Annals of Diagnostic Pathology. 26, p. 38-42 5 p.

  Research output: Contribution to journal › Article › peer-review
  4 Scopus citations

• Significance of a minor high-grade component in a low-grade noninvasive papillary urothelial carcinoma of bladder

  Reis, L. O., Taheri, D., Chaux, A., Guner, G., Mendoza Rodriguez, M. A., Bivalacqua, T. J., Schoenberg, M. P., Epstein, J. I. & Netto, G. J., Jan 1 2016, In: Human Pathology. 47, 1, p. 20-25 6 p.

  Research output: Contribution to journal › Article › peer-review
  22 Scopus citations

• Significance of anti-HBc screening of blood donors & its association with occult hepatitis B virus infection: Implications for blood transfusion

  Asim, M., Ali, R., Khan, L. A., Husain, S. A., Singla, R. & Kar, P., Sep 2010, In: Indian Journal of Medical Research. 132, 9, p. 312-317 6 p.

  Research output: Contribution to journal › Article › peer-review
  41 Scopus citations

• Significance of antinuclear antibody testing in unexplained second and third trimester fetal deaths

  Incerpi, M. H., Banks, E. H., Goodwein, S. N., Samadi, R. & Goodwin, T. M., 1998, In: Journal of Maternal-Fetal and Neonatal Medicine. 7, 2, p. 61-64 4 p.

  Research output: Contribution to journal › Article › peer-review
  5 Scopus citations

• Significance of Co-expression of Epidermal Growth Factor Receptor and Ki67 on Clinical Outcome in Patients With Anal Cancer Treated With Chemoradiotherapy: An Analysis of NRG Oncology RTOG 9811

  Doll, C. M., Moughan, J., Klimowicz, A., Ho, C. K., Kornaga, E. N., Lees-Miller, S. P., Ajani, J. A., Crane, C. H., Kachnic, L. A., Okawara, G. S., Berk, L. B., Roof, K. S., Becker, M. J., Grisell, D. L., Ellis, R. J., Sperduto, P. W., Marsa, G. W., Guha, C. & Magliocco, A. M., Mar 1 2017, In: International Journal of Radiation Oncology Biology Physics. 97, 3, p. 554-562 9 p.

  Research output: Contribution to journal › Article › peer-review
  8 Scopus citations

• Significance of depression and cognitive impairmenmt in patients undergoing programed stimulation of cardiac arrhythmias

  Kennedy, G. J., Hofer, M. A., Cohen, D., Shindledecker, R. & Fisher, J. D., 1987, In: Psychosomatic Medicine. 49, 4, p. 410-421 12 p.

  Research output: Contribution to journal › Article › peer-review
  65 Scopus citations

• Significance of early aminotransferase elevation after liver transplantation

  Rosen, H. R., Martin, P., Goss, J., Donovan, J., Melinek, J., Rudich, S., Imagawa, D. K., Kinkhabwala, M., Seu, P., Busuttil, R. W. & Shackleton, C. R., Jan 15 1998, In: Transplantation. 65, 1, p. 68-72 5 p.

  Research output: Contribution to journal › Article › peer-review
  83 Scopus citations

• Significance of endotension, endoleak, and aneurysm pulsatility after endovascular repair

  Mehta, M., Veith, F. J., Ohki, T., Lipsitz, E. C., Cayne, N. S. & Darling, R. C., Apr 1 2003, In: Journal of Vascular Surgery. 37, 4, p. 842-846 5 p.

  Research output: Contribution to journal › Article › peer-review
  53 Scopus citations

• Significance of epicardial and intrathoracic adipose tissue volume among type 1 diabetes patients in the DCCT/EDIC: A pilot study

  DCCT/EDIC Research Group, Jul 1 2016, In: PloS one. 11, 7, e0159958.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  14 Scopus citations

• Significance of extramucosal residual tumor at the bronchial resection margin

  Kaiser, L. R., Fleshner, P., Keller, S. & Martini, N., Feb 1989, In: The Annals of Thoracic Surgery. 47, 2, p. 265-269 5 p.

  Research output: Contribution to journal › Article › peer-review
  63 Scopus citations

• Significance of histologic pattern of carcinoma and sarcoma components on survival outcomes of uterine carcinosarcoma

  Matsuo, K., Takazawa, Y., Ross, M. S., Elishaev, E., Podzielinski, I., Yunokawa, M., Sheridan, T. B., Bush, S. H., Klobocista, M. M., Blake, E. A., Takano, T., Matsuzaki, S., Baba, T., Satoh, S., Shida, M., Nishikawa, T., Ikeda, Y., Adachi, S., Yokoyama, T., Takekuma, M., & 52 othersFujiwara, K., Hazama, Y., Kadogami, D., Moffitt, M. N., Takeuchi, S., Nishimura, M., Iwasaki, K., Ushioda, N., Johnson, M. S., Yoshida, M., Hakam, A., Li, S. W., Richmond, A. M., Machida, H., Mhawech-Fauceglia, P., Ueda, Y., Yoshino, K., Yamaguchi, K., Oishi, T., Kajiwara, H., Hasegawa, K., Yasuda, M., Kawana, K., Suda, K., Miyake, T. M., Moriya, T., Yuba, Y., Morgan, T., Fukagawa, T., Wakatsuki, A., Sugiyama, T., Pejovic, T., Nagano, T., Shimoya, K., Andoh, M., Shiki, Y., Enomoto, T., Sasaki, T., Fujiwara, K., Mikami, M., Shimada, M., Konishi, I., Kimura, T., Post, M. D., Shahzad, M. M., Im, D. D., Yoshida, H., Omatsu, K., Ueland, F. R., Kelley, J. L., Karabakhtsian, R. G. & Roman, L. D., Jul 1 2016, In: Annals of Oncology. 27, 7, p. 1257-1266 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  49 Scopus citations

• Significance of inducible nitric oxide synthase in acute myocarditis caused by Trypanosoma cruzi (Tulahuen strain)

  Chandra, M., Tanowitz, H. B., Petkova, S. B., Huang, H., Weiss, L. M., Wittner, M., Factor, S. M., Shtutin, V., Jelicks, L. A., Chan, J. & Shirani, J., 2002, In: International Journal for Parasitology. 32, 7, p. 897-905 9 p.

  Research output: Contribution to journal › Article › peer-review
  44 Scopus citations

• Significance of isolated H-V interval prolongation in symptomatic patients without documented heart block

  Altschuler, H., Fisher, J. D. & Furman, S., Jan 1979, In: American heart journal. 97, 1, p. 19-26 8 p.

  Research output: Contribution to journal › Article › peer-review
  37 Scopus citations

• Significance of leukocytosis after cardiac device implantation

  Tompkins, C., Cheng, A., Brinker, J. A., Marine, J. E., Nazarian, S., Spragg, D. D., Sinha, S., Halperin, H., Tomaselli, G. F., Berger, R. D., Calkins, H. & Henrikson, C. A., Jun 1 2013, In: American Journal of Cardiology. 111, 11, p. 1608-1612 5 p.

  Research output: Contribution to journal › Article › peer-review
  6 Scopus citations

• Significance of Lymphovascular Space Invasion by the Sarcomatous Component in Uterine Carcinosarcoma

  Matsuo, K., Takazawa, Y., Ross, M. S., Elishaev, E., Yunokawa, M., Sheridan, T. B., Bush, S. H., Klobocista, M. M., Blake, E. A., Takano, T., Baba, T., Satoh, S., Shida, M., Ikeda, Y., Adachi, S., Yokoyama, T., Takekuma, M., Yanai, S., Takeuchi, S., Nishimura, M., & 30 othersIwasaki, K., Johnson, M. S., Yoshida, M., Hakam, A., Machida, H., Mhawech-Fauceglia, P., Ueda, Y., Yoshino, K., Kajiwara, H., Hasegawa, K., Yasuda, M., Miyake, T. M., Moriya, T., Yuba, Y., Morgan, T., Fukagawa, T., Pejovic, T., Nagano, T., Sasaki, T., Richmond, A. M., Post, M. D., Shahzad, M. M. K., Im, D. D., Yoshida, H., Enomoto, T., Omatsu, K., Ueland, F. R., Kelley, J. L., Karabakhtsian, R. G. & Roman, L. D., Sep 1 2018, In: Annals of Surgical Oncology. 25, 9, p. 2756-2766 11 p.

  Research output: Contribution to journal › Article › peer-review
  4 Scopus citations

• Significance of Pleural Effusion in Patients with Acute Pancreatitis

  Gumaste, V., Singh, V. & Dave, P., Jul 1992, In: The American Journal of Gastroenterology. 87, 7, p. 871-874 4 p.

  Research output: Contribution to journal › Article › peer-review
  26 Scopus citations

• Significance of post-traumatic maxillary sinus fluid, or lack of fluid, in a level II trauma population

  Friedman, A., Burns, J. & Scheinfeld, M. H., Dec 1 2015, In: Emergency Radiology. 22, 6, p. 661-666 6 p.

  Research output: Contribution to journal › Article › peer-review
  2 Scopus citations

• Significance of preoperative radiographic pancreatic density in predicting pancreatic fistula after surgery for pancreatic neuroendocrine tumors

  Assadipour, Y., Azoury, S. C., Schaub, N. N., Hong, Y., Eil, R., Inchauste, S. M., Steinberg, S. M., Venkatesan, A. M., Libutti, S. K. & Hughes, M. S., Jul 1 2016, In: American Journal of Surgery. 212, 1, p. 40-46 7 p.

  Research output: Contribution to journal › Article › peer-review
  3 Scopus citations

• Significance of Pseudomonas in perforated appendicitis in children

  Crain, E., Kaufman, I., Weinberg, G. & Glaser, J., Jan 1 1998, In: Emergency and Office Pediatrics. 11, 1, p. 24-26 3 p.

  Research output: Contribution to journal › Article › peer-review

• Significance of single and multi-voxel ¹H magnetic resonance spectroscopy in the quantification of myocellular lipid in young non-obese Asian Indian males

  Livingstone, R. S., Thomas, A. J., Dasgupta, R., Anoop, S., Kurian, M. E., Hawkins, M. & Thomas, N., Jan 2021, In: Magnetic Resonance Imaging. 75, p. 65-71 7 p.

  Research output: Contribution to journal › Article › peer-review

• Significance of skeletal uptake detected on radionuclide renal perfusion studies

  Zuckier, L. S., Weissmann, H. S., Kaplun, L., Schlossberg, I., Gade, M. F. & Freeman, L. M., 1987, In: Clinical nuclear medicine. 12, 6, p. 448-452 5 p.

  Research output: Contribution to journal › Article › peer-review
  8 Scopus citations

• Significance of the amyloidogenic transthyretin Val 122 Ile allele in African Americans in the Arteriosclerosis Risk in Communities (ARIC) and Cardiovascular Health (CHS) Studies

  Buxbaum, J., Alexander, A., Koziol, J., Tagoe, C., Fox, E. & Kitzman, D., May 2010, In: American heart journal. 159, 5, p. 864-870 7 p.

  Research output: Contribution to journal › Article › peer-review
  71 Scopus citations

• Significant Benefit of Uninterrupted DOACs Versus VKA During Catheter Ablation of Atrial Fibrillation

  Romero, J., Cerrud-Rodriguez, R. C., Alviz, I., Diaz, J. C., Rodriguez, D., Arshad, S., Cerna, L., Taveras, J., Grupposo, V., Natale, A., Garcia, M. & Di Biase, L., Dec 2019, In: JACC: Clinical Electrophysiology. 5, 12, p. 1396-1405 10 p.

  Research output: Contribution to journal › Article › peer-review
  17 Scopus citations

• Significant but reasonable radiation exposure from computed tomography-related medical imaging in the ICU

  Slovis, B. H., Shah, K. H., Yeh, D. D., Seethala, R., Kaafarani, H. M. A., Eikermann, M., Raja, A. S. & Lee, J., Apr 1 2016, In: Emergency Radiology. 23, 2, p. 141-146 6 p.

  Research output: Contribution to journal › Article › peer-review
  8 Scopus citations

• Significant Change in Predicted Risk of Biochemical Recurrence After Radical Prostatectomy More Common in Black Than in White Men

  Laudano, M. A., Badani, K. K., McCann, T. R., Mann, M. J., Ritch, C., Desai, M., Benson, M. C. & McKiernan, J. M., Sep 2009, In: Urology. 74, 3, p. 660-664 5 p.

  Research output: Contribution to journal › Article › peer-review
  4 Scopus citations

• Significant contribution of spleen cells in mediating the lethal effects of endotoxin in vivo

  Glode, L. M., Mergenhagen, S. E. & Rosenstreich, D. L., Dec 1 1976, In: Infection and Immunity. 14, 3, p. 626-630 5 p.

  Research output: Contribution to journal › Article › peer-review
  28 Scopus citations

• Significant expansion of the REST/NRSF cistrome in human versus mouse embryonic stem cells: Potential implications for neural development

  Rockowitz, S. & Zheng, D., Jul 13 2015, In: Nucleic acids research. 43, 12, p. 5730-5743 14 p.

  Research output: Contribution to journal › Article › peer-review
  26 Scopus citations

• Significantly lower P-glycoprotein expression in acute promyelocytic leukemia than in other types of acute myeloid leukemia: Immunological, molecular and functional analyses

  Paietta, E., Andersen, J., Racevskis, J., Gallagher, R., Bennett, J., Yunis, J., Cassileth, P. & Wiernik, P. H., Jun 1994, In: Leukemia. 8, 6, p. 968-973 6 p.

  Research output: Contribution to journal › Article › peer-review
  100 Scopus citations

• Significant physiological roles of ancillary penile nerves on increase in intracavernous pressure in rats: Experiments using electrical stimulation of the medial preoptic area

  Sato, Y., Rehman, J., Santizo, C., Melman, A. & Christ, G. J., 2001, In: International journal of impotence research. 13, 2, p. 82-88 7 p.

  Research output: Contribution to journal › Article › peer-review
  13 Scopus citations

• Significant racial differences in the incidence and behavior of the follicular variant of papillary thyroid carcinoma

  Mehta, V., Ow, T. J., Kim, S., Tharakan, T., Schiff, B., Smith, R. V. & In, H., May 2019, In: Head and Neck. 41, 5, p. 1403-1411 9 p.

  Research output: Contribution to journal › Article › peer-review
  3 Scopus citations

• Significant responses to platinum-based chemotherapy in renal medullary carcinoma

  Strouse, J. J., Spevak, M., Mack, A. K., Arceci, R. J., Small, D. & Loeb, D. M., Apr 1 2005, In: Pediatric Blood and Cancer. 44, 4, p. 407-411 5 p.

  Research output: Contribution to journal › Article › peer-review
  43 Scopus citations

• Significant structural and functional change of an antigen-binding site by a distant amino acid substitution: Proposal of a structural mechanism

  Chien, N. C., Roberts, V. A., Giusti, A. M., Scharff, M. D. & Getzoff, E. D., 1989, In: Proceedings of the National Academy of Sciences of the United States of America. 86, 14, p. 5532-5536 5 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  61 Scopus citations

• Significant Variation in Exercise Recommendations for Youth with Cardiomyopathies or Fontan Circulation: An Advanced Cardiac Therapies Improving Outcomes Network Learning Survey

  Khoury, M., Wittekind, S., Lal, A. K., Conway, J., Bansal, N., Lorts, A., Rosenthal, D. & Burstein, D., 2021, (Accepted/In press) In: Circulation: Heart Failure. e008738.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  2 Scopus citations

• Sign language: Its history and contribution to the understanding of the biological nature of language

  Ruben, R. J., May 27 2005, In: Acta Oto-Laryngologica. 125, 5, p. 464-467 4 p.

  Research output: Contribution to journal › Article › peer-review
  17 Scopus citations