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  Transition of care for pediatric and adult patients with venous thromboembolism: A National Quality Improvement Project from the American Thrombosis and Hemostasis Network (ATHN)

  Study Investigators, Apr 2021, In: Thrombosis Research. 200, p. 23-29 7 p.

  Research output: Contribution to journal › Article › peer-review
  1 Scopus citations

• Transition of patients with sickle cell disease from pediatric to adult care: Assessing patient readiness

  McPherson, M., Thaniel, L. & Minniti, C. P., Jul 1 2009, In: Pediatric Blood and Cancer. 52, 7, p. 838-841 4 p.

  Research output: Contribution to journal › Article › peer-review
  92 Scopus citations

• Transition path sampling study of the reaction catalyzed by purine nucleoside phosphorylase

  Saen-oon, S., Schramm, V. L. & Schwartz, S. D., 2008, In: Zeitschrift fur Physikalische Chemie. 222, 8-9, p. 1359-1374 16 p.

  Research output: Contribution to journal › Article › peer-review
  13 Scopus citations

• Transition-state analogs as inhibitors of human and malarial hypoxanthine-guanine phosphoribosyltransferases

  Li, C. M., Tyler, P. C., Furneaux, R. H., Kicska, G., Xu, Y., Grubmeyer, C., Girvin, M. E. & Schramm, V. L., 1999, In: Nature Structural Biology. 6, 6, p. 582-587 6 p.

  Research output: Contribution to journal › Article › peer-review
  101 Scopus citations

• Transition state analogs of 5′-methylthioadenosine nucleosidase disrupt quorum sensing

  Gutierrez, J. A., Crowder, T., Rinaldo-Matthis, A., Ho, M. C., Almo, S. C. & Schramm, V. L., Apr 2 2009, In: Nature Chemical Biology. 5, 4, p. 251-257 7 p.

  Research output: Contribution to journal › Article › peer-review
  130 Scopus citations

• Transition state analogue discrimination by related purine nucleoside phosphorylases

  Taylor Ringia, E. A., Tyler, P. C., Evans, G. B., Furneaux, R. H., Murkin, A. S. & Schramm, V. L., Jun 7 2006, In: Journal of the American Chemical Society. 128, 22, p. 7126-7127 2 p.

  Research output: Contribution to journal › Article › peer-review
  32 Scopus citations

• Transition State Analogue Inhibitors of 5′-Deoxyadenosine/5′-Methylthioadenosine Nucleosidase from Mycobacterium tuberculosis

  Namanja-Magliano, H. A., Evans, G. B., Harijan, R. K., Tyler, P. C. & Schramm, V. L., Sep 26 2017, In: Biochemistry. 56, 38, p. 5090-5098 9 p.

  Research output: Contribution to journal › Article › peer-review
  11 Scopus citations

• Transition state analogue inhibitors of human methylthioadenosine phosphorylase and bacterial methylthioadenosine/S-adenosylhomocysteine nucleosidase incorporating acyclic ribooxacarbenium ion mimics

  Clinch, K., Evans, G. B., Fröhlich, R. F. G., Gulab, S. A., Gutierrez, J. A., Mason, J. M., Schramm, V. L., Tyler, P. C. & Woolhouse, A. D., Sep 1 2012, In: Bioorganic and Medicinal Chemistry. 20, 17, p. 5181-5187 7 p.

  Research output: Contribution to journal › Article › peer-review
  12 Scopus citations

• Transition state analogue inhibitors of N-ribosyltransferases: new drugs by targeting nucleoside processing enzymes.

  Evans, G. B., Furneaux, R. H., Kelly, P. M., Schramm, V. L. & Tyler, P. C., 2007, In: Nucleic acids symposium series (2004). 51, p. 63-64 2 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  2 Scopus citations

• Transition state analogue inhibitors of protozoan nucleoside hydrolases

  Furneaux, R. H., Schramm, V. L. & Tyler, P. C., Nov 1999, In: Bioorganic and Medicinal Chemistry. 7, 11, p. 2599-2606 8 p.

  Research output: Contribution to journal › Article › peer-review
  41 Scopus citations

• Transition state analogue inhibitors of purine nucleoside phosphorylase from Plasmodium falciparum

  Kicska, G. A., Tyler, P. C., Evans, G. B., Furneaux, R. H., Kim, K. & Schramm, V. L., Feb 1 2002, In: Journal of Biological Chemistry. 277, 5, p. 3219-3225 7 p.

  Research output: Contribution to journal › Article › peer-review
  97 Scopus citations

• Transition state analogue of MTAP extends lifespan of APC^Min/+ mice

  Firestone, R. S., Feng, M., Basu, I., Peregrina, K., Augenlicht, L. H. & Schramm, V. L., Dec 2021, In: Scientific reports. 11, 1, 8844.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  1 Scopus citations

• Transition State Analogues Enhanced by Fragment-Based Structural Analysis: Bacterial Methylthioadenosine Nucleosidases

  Zhang, D., Burdette, B. E., Wang, Z., Karn, K., Li, H. Y., Schramm, V. L., Tyler, P. C., Evans, G. B. & Wang, S., Feb 25 2020, In: Biochemistry. 59, 7, p. 831-835 5 p.

  Research output: Contribution to journal › Article › peer-review
  1 Scopus citations

• Transition state analogues for enzymes of nucleic acid metabolism.

  Schramm, V. L., 2003, In: Nucleic acids research. Supplement (2001). 3, p. 107-108 2 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  10 Scopus citations

• Transition state analogues in quorum sensing and SAM recycling.

  Schramm, V. L., Gutierrez, J. A., Cordovano, G., Basu, I., Guha, C., Belbin, T. J., Evans, G. B., Tyler, P. C. & Furneaux, R. H., 2008, In: Nucleic acids symposium series (2004). 52, p. 75-76 2 p.

  Research output: Contribution to journal › Article › peer-review
  24 Scopus citations

• Transition state analogues in structures of ricin and saporin ribosome-inactivating proteins

  Ho, M. C., Sturm, M. B., Almo, S. C. & Schramm, V. L., Dec 1 2009, In: Proceedings of the National Academy of Sciences of the United States of America. 106, 48, p. 20276-20281 6 p.

  Research output: Contribution to journal › Article › peer-review
  52 Scopus citations

• Transition-State Analogues of Campylobacter jejuni 5′-Methylthioadenosine Nucleosidase

  Ducati, R. G., Harijan, R. K., Cameron, S. A., Tyler, P. C., Evans, G. B. & Schramm, V. L., Nov 16 2018, In: ACS Chemical Biology. 13, 11, p. 3173-3183 11 p.

  Research output: Contribution to journal › Article › peer-review
  5 Scopus citations

• Transition-State Analogues of Phenylethanolamine N-Methyltransferase

  Mahmoodi, N., Harijan, R. K. & Schramm, V. L., Aug 19 2020, In: Journal of the American Chemical Society. 142, 33, p. 14222-14233 12 p.

  Research output: Contribution to journal › Article › peer-review
  5 Scopus citations

• Transition state analogues of plasmodium falciparum and human orotate phosphoribosyltransferases

  Zhang, Y., Evans, G. B., Clinch, K., Crump, D. R., Harris, L. D., Fröhlich, R. F. G., Tyler, P. C., Hazleton, K. Z., Cassera, M. B. & Schramm, V. L., Nov 29 2013, In: Journal of Biological Chemistry. 288, 48, p. 34746-34754 9 p.

  Research output: Contribution to journal › Article › peer-review
  18 Scopus citations

• Transition state analogues rescue ribosomes from saporin-L1 ribosome inactivating protein

  Sturm, M. B., Tyler, P. C., Evans, G. B. & Schramm, V. L., Oct 20 2009, In: Biochemistry. 48, 41, p. 9941-9948 8 p.

  Research output: Contribution to journal › Article › peer-review
  18 Scopus citations

• Transition-state analysis for depurination of DNA by ricin A-chain

  Chen, X. Y., Berti, P. J. & Schramm, V. L., Jul 19 2000, In: Journal of the American Chemical Society. 122, 28, p. 6527-6534 8 p.

  Research output: Contribution to journal › Article › peer-review
  62 Scopus citations

• Transition-state analysis for depurination of DNA by Ricin A-chain

  Chen, X. Y., Berti, P. J. & Schramm, V. L., Jul 19 2000, In: Journal of the American Chemical Society. 122, 28, p. X

  Research output: Contribution to journal › Article › peer-review
  10 Scopus citations

• Transition State Analysis for Human and Plasmodium falciparum Purine Nucleoside Phosphorylases

  Lewandowicz, A. & Schramm, V. L., Feb 17 2004, In: Biochemistry. 43, 6, p. 1458-1468 11 p.

  Research output: Contribution to journal › Article › peer-review
  142 Scopus citations

• Transition-state analysis of 2-O acetyl-ADP-ribose hydrolysis by human macrodomain 1

  Hirsch, B. M., Burgos, E. S. & Schramm, V. L., Oct 17 2014, In: ACS Chemical Biology. 9, 10, p. 2255-2262 8 p.

  Research output: Contribution to journal › Article › peer-review
  10 Scopus citations

• Transition State Analysis of Adenosine Triphosphate Phosphoribosyltransferase

  Moggré, G. J., Poulin, M. B., Tyler, P. C., Schramm, V. L. & Parker, E. J., Oct 20 2017, In: ACS Chemical Biology. 12, 10, p. 2662-2670 9 p.

  Research output: Contribution to journal › Article › peer-review
  8 Scopus citations

• Transition-State Analysis of AMP Deaminase

  Merkler, D. J., Kline, P. C., Weiss, P. & Schramm, V. L., 1993, In: Biochemistry. 32, 48, p. 12993-13001 9 p.

  Research output: Contribution to journal › Article › peer-review
  44 Scopus citations

• Transition-State Analysis of a V_max Mutant of AMP Nucleosidase by the Application of Heavy-Atom Kinetic Isotope Effects

  Parkin, D. W., Mentch, F., Banks, G. A., Horenstein, B. A. & Schramm, V. L., May 1 1991, In: Biochemistry. 30, 18, p. 4586-4594 9 p.

  Research output: Contribution to journal › Article › peer-review
  39 Scopus citations

• Transition state analysis of NAD⁺ hydrolysis by the cholera toxin catalytic subunit

  Rising, K. A. & Schramm, V. L., Jan 8 1997, In: Journal of the American Chemical Society. 119, 1, p. 27-37 11 p.

  Research output: Contribution to journal › Article › peer-review
  53 Scopus citations

• Transition-State Analysis of Nucleoside Hydrolase from Crithidia fasciculata

  Horenstein, B. A., Estupiñán, B., Schramm, V. L. & Parkin, D. W., Nov 1 1991, In: Biochemistry. 30, 44, p. 10788-10795 8 p.

  Research output: Contribution to journal › Article › peer-review
  152 Scopus citations

• Transition-state analysis of S. pneumoniae 5′-methylthioadenosine nucleosidase

  Singh, V. & Schramm, V. L., Mar 14 2007, In: Journal of the American Chemical Society. 129, 10, p. 2783-2795 13 p.

  Research output: Contribution to journal › Article › peer-review
  41 Scopus citations

• Transition state analysis of the arsenolytic depyrimidination of thymidine by human thymidine phosphorylase

  Schwartz, P. A., Vetticatt, M. J. & Schramm, V. L., Mar 1 2011, In: Biochemistry. 50, 8, p. 1412-1420 9 p.

  Research output: Contribution to journal › Article › peer-review
  21 Scopus citations

• Transition state analysis of thymidine hydrolysis by human thymidine phosphorylase

  Schwartz, P. A., Vetticatt, M. J. & Schramm, V. L., Sep 29 2010, In: Journal of the American Chemical Society. 132, 38, p. 13425-13433 9 p.

  Research output: Contribution to journal › Article › peer-review
  23 Scopus citations

• Transition-state analysis of Trypanosoma cruzi uridine phosphorylase- catalyzed arsenolysis of uridine

  Silva, R. G., Vetticatt, M. J., Merino, E. F., Cassera, M. B. & Schramm, V. L., Jun 29 2011, In: Journal of the American Chemical Society. 133, 25, p. 9923-9931 9 p.

  Research output: Contribution to journal › Article › peer-review
  11 Scopus citations

• Transition state for the NSD2-catalyzed methylation of histone H3 lysine 36

  Poulin, M. B., Schneck, J. L., Matico, R. E., McDevitt, P. J., Huddleston, M. J., Hou, W., Johnson, N. W., Thrall, S. H., Meek, T. D. & Schramm, V. L., Feb 2 2016, In: Proceedings of the National Academy of Sciences of the United States of America. 113, 5, p. 1197-1201 5 p.

  Research output: Contribution to journal › Article › peer-review
  37 Scopus citations

• Transition-state interactions revealed in purine nucleoside phosphorylase by binding isotope effects

  Murkin, A. S., Tyler, P. C. & Schramm, V. L., Feb 20 2008, In: Journal of the American Chemical Society. 130, 7, p. 2166-2167 2 p.

  Research output: Contribution to journal › Article › peer-review
  20 Scopus citations

• Transition state model and mechanism of nucleophilic aromatic substitution reactions catalyzed by human glutathione S-transferase M1a-1a

  Patskovsky, Y., Patskovska, L., Almo, S. C. & Listowsky, I., Mar 28 2006, In: Biochemistry. 45, 12, p. 3852-3862 11 p.

  Research output: Contribution to journal › Article › peer-review
  38 Scopus citations

• Transition state of the sulfuryl transfer reaction of estrogen sulfotransferase

  Hoff, R. H., Czyryca, P. G., Sun, M., Leyh, T. S. & Hengge, A. C., Oct 13 2006, In: Journal of Biological Chemistry. 281, 41, p. 30645-30649 5 p.

  Research output: Contribution to journal › Article › peer-review
  18 Scopus citations

• Transition states

  Schramm, V. L., Nov 20 2009, In: Journal of Biological Chemistry. 284, 47, p. 32201-32208 8 p.

  Research output: Contribution to journal › Article › peer-review
  5 Scopus citations

• Transition states and transition state analogue interactions with enzymes

  Schramm, V. L., Apr 21 2015, In: Accounts of Chemical Research. 48, 4, p. 1032-1039 8 p.

  Research output: Contribution to journal › Article › peer-review
  44 Scopus citations

• Transition states for glucopyranose interconversion

  Lewis, B. E., Choytun, N., Schramm, V. L. & Bennet, A. J., Apr 19 2006, In: Journal of the American Chemical Society. 128, 15, p. 5049-5058 10 p.

  Research output: Contribution to journal › Article › peer-review
  58 Scopus citations

• Transition states of native and drug-resistant HIV-1 protease are the same

  Kipp, D. R., Hirschi, J. S., Wakata, A., Goldstein, H. & Schramm, V. L., Apr 24 2012, In: Proceedings of the National Academy of Sciences of the United States of America. 109, 17, p. 6543-6548 6 p.

  Research output: Contribution to journal › Article › peer-review
  20 Scopus citations

• Transition states of plasmodium falciparum and human orotate phosphoribosyltransferases

  Zhang, Y., Luo, M. & Schramm, V. L., Apr 8 2009, In: Journal of the American Chemical Society. 131, 13, p. 4685-4694 10 p.

  Research output: Contribution to journal › Article › peer-review
  43 Scopus citations

• Transition State Structure and Inhibition of Rv0091, a 5′-Deoxyadenosine/5′-methylthioadenosine Nucleosidase from Mycobacterium tuberculosis

  Namanja-Magliano, H. A., Stratton, C. F. & Schramm, V. L., Jun 17 2016, In: ACS Chemical Biology. 11, 6, p. 1669-1676 8 p.

  Research output: Contribution to journal › Article › peer-review
  11 Scopus citations

• Transition State Structure for ADP-Ribosylation of Eukaryotic Elongation Factor 2 Catalyzed by Diphtheria Toxin

  Parikh, S. L. & Schramm, V. L., Feb 10 2004, In: Biochemistry. 43, 5, p. 1204-1212 9 p.

  Research output: Contribution to journal › Article › peer-review
  41 Scopus citations

• Transition-state structure for the ADP-ribosylation of recombinant G(iα1) subunits by pertussis toxin

  Scheuring, J., Berti, P. J. & Schramm, V. L., Mar 3 1998, In: Biochemistry. 37, 9, p. 2748-2758 11 p.

  Research output: Contribution to journal › Article › peer-review
  45 Scopus citations

• Transition state structure for the hydrolysis of NAD⁺ catalyzed by diphtheria toxin

  Berti, P. J., Blanke, S. R. & Schramm, V. L., Dec 17 1997, In: Journal of the American Chemical Society. 119, 50, p. 12079-12088 10 p.

  Research output: Contribution to journal › Article › peer-review
  79 Scopus citations

• Transition state structure of 5′-methylthioadenosine/S- adenosylhomocysteine nucleosidase from Escherichia coli and its similarity to transition state analogues

  Singh, V., Lee, J. E., Núñez, S., Howell, P. L. & Schramm, V. L., Sep 6 2005, In: Biochemistry. 44, 35, p. 11647-11659 13 p.

  Research output: Contribution to journal › Article › peer-review
  93 Scopus citations

• Transition state structure of E. coli tRNA-specific adenosine deaminase

  Luo, M. & Schramm, V. L., Feb 27 2008, In: Journal of the American Chemical Society. 130, 8, p. 2649-2655 7 p.

  Research output: Contribution to journal › Article › peer-review
  25 Scopus citations

• Transition-state structure of human 5′-methylthioadenosine phosphorylase

  Singh, V. & Schramm, V. L., Nov 15 2006, In: Journal of the American Chemical Society. 128, 45, p. 14691-14696 6 p.

  Research output: Contribution to journal › Article › peer-review
  44 Scopus citations

• Transition-state structure of Neisseria meningitides 5′- methylthioadenosine/S-adenosylhomocysteine nucleosidase

  Singh, V., Luo, M., Brown, R. L., Norris, G. E. & Schramm, V. L., Nov 14 2007, In: Journal of the American Chemical Society. 129, 45, p. 13831-13833 3 p.

  Research output: Contribution to journal › Article › peer-review
  29 Scopus citations