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  Synthesis and biological activity in the camptothecin series

  Danishefsky, S., Quick, J. & Horwitz, S. B., 1973, In: Tetrahedron Letters. 14, 27, p. 2525-2528 4 p.

  Research output: Contribution to journal › Article › peer-review
  5 Scopus citations

• Synthesis and biological activity of alkynoic acids derivatives against mycobacteria

  Vilchèze, C., Leung, L. W., Bittman, R. & Jacobs, W. R., Jan 1 2016, In: Chemistry and Physics of Lipids. 194, p. 125-138 14 p.

  Research output: Contribution to journal › Article › peer-review
  3 Scopus citations

• Synthesis and biological activity of diaryl ether inhibitors of malarial enoyl acyl carrier protein reductase. Part 2: 2′-Substituted triclosan derivatives

  Freundlich, J. S., Yu, M., Lucumi, E., Kuo, M., Tsai, H. C., Valderramos, J. C., Karagyozov, L., Jacobs, W. R., Schiehser, G. A., Fidock, D. A., Jacobus, D. P. & Sacchettini, J. C., Apr 15 2006, In: Bioorganic and Medicinal Chemistry Letters. 16, 8, p. 2163-2169 7 p.

  Research output: Contribution to journal › Article › peer-review
  11 Scopus citations

• Synthesis and biological activity of α-glucosyl C24:0 and C20:2 ceramides

  Jervis, P. J., Veerapen, N., Bricard, G., Cox, L. R., Porcelli, S. A. & Besra, G. S., 2010, In: Bioorganic and Medicinal Chemistry Letters. 20, 12, p. 3475-3478 4 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  22 Scopus citations

• Synthesis and biological activity of α-l-fucosyl ceramides, analogues of the potent agonist, α-d-galactosyl ceramide KRN7000

  Veerapen, N., Reddington, F., Bricard, G., Porcelli, S. A. & Besra, G. S., Jun 1 2010, In: Bioorganic and Medicinal Chemistry Letters. 20, 11, p. 3223-3226 4 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  14 Scopus citations

• Synthesis and biological evaluation of novel 3′-difluorovinyl taxoids

  Kuznetsova, L., Sun, L., Chen, J., Zhao, X., Seitz, J., Das, M., Li, Y., Veith, J. M., Pera, P., Bernacki, R. J., Xia, S., Horwitz, S. B. & Ojima, I., Nov 2012, In: Journal of Fluorine Chemistry. 143, p. 177-188 12 p.

  Research output: Contribution to journal › Article › peer-review
  25 Scopus citations

• Synthesis and biological studies of new lipid-soluble cisplatin analogues entrapped in liposomes

  Al-Baker, S., Perez-Soler, R. & Khokhar, A. R., Aug 1 1992, In: Journal of Inorganic Biochemistry. 47, 2, p. 99-108 10 p.

  Research output: Contribution to journal › Article › peer-review
  5 Scopus citations

• Synthesis and breakdown of fibrillar collagens: Concomitant phenomena in ovarian cancer

  Santala, M., Risteli, J., Risteli, L., Puistola, U., Kacinski, B. M., Stanley, E. R. & Kauppila, A., Jun 1998, In: British Journal of Cancer. 77, 11, p. 1825-1831 7 p.

  Research output: Contribution to journal › Article › peer-review
  22 Scopus citations

• Synthesis and characterization of a series of hydrophobic antitumor bis(carboxylato) (1, 2-diaminocyclohexane) platinum(ii) complexes

  Al-Baker, S., Perez-Soler, R. & Khokhar, A. R., Jun 1 1993, In: Journal of Coordination Chemistry. 29, 1-2, p. 1-6 6 p.

  Research output: Contribution to journal › Article › peer-review
  1 Scopus citations

• Synthesis and characterization of bioconjugates of S-layer proteins

  Sampathkumar, P. & Gilchrist, M. L., 2004, In: Bioconjugate Chemistry. 15, 4, p. 685-693 9 p.

  Research output: Contribution to journal › Article › peer-review
  5 Scopus citations

• Synthesis and characterization of branched phosphopeptides: Prototype consolidated ligands for SH(32) domains

  Xu, Q., Zheng, J., Cowburn, D. & Barany, G., 1996, In: Letters in Peptide Science. 3, 1, p. 31-36 6 p.

  Research output: Contribution to journal › Article › peer-review
  1 Scopus citations

• Synthesis and characterization of nanosized metals embedded in polystyrene matrix

  Mahajan, D., Desai, A., Rafailovich, M., Cui, M. H. & Yang, N. L., Jan 2006, In: Composites Part B: Engineering. 37, 1, p. 74-80 7 p.

  Research output: Contribution to journal › Article › peer-review
  18 Scopus citations

• Synthesis and characterization of oxymethylene-linked 2-vinylpyridine/oxyethylene multiblock copolymers

  Cui, M. H., Xie, H. Q. & Guo, J. S., Jun 1 1998, In: Angewandte Makromolekulare Chemie. 257, p. 37-42 6 p.

  Research output: Contribution to journal › Article › peer-review
  3 Scopus citations

• Synthesis and Characterization of Transition-State Analogue Inhibitors against Human DNA Methyltransferase 1

  Lamiable-Oulaidi, F., Harijan, R. K., Shaffer, K. J., Crump, D. R., Sun, Y., Du, Q., Gulab, S. A., Khan, A. A., Luxenburger, A., Woolhouse, A. D., Sidoli, S., Tyler, P. C. & Schramm, V. L., Apr 14 2022, In: Journal of Medicinal Chemistry. 65, 7, p. 5462-5494 33 p.

  Research output: Contribution to journal › Article › peer-review
  1 Scopus citations

• Synthesis and comparative antibacterial activity of verdamicin C2 and C2a. A new oxidation of primary allylic azides in dihydro[2H]pyrans

  Hanessian, S., Szychowski, J. & Pablo Maianti, J., Jan 15 2009, In: Organic Letters. 11, 2, p. 429-432 4 p.

  Research output: Contribution to journal › Article › peer-review
  18 Scopus citations

• Synthesis and degradation of FtsZ quantitatively predict the first cell division in starved bacteria

  Sekar, K., Rusconi, R., Sauls, J. T., Fuhrer, T., Noor, E., Nguyen, J., Fernandez, V. I., Buffing, M. F., Berney, M., Jun, S., Stocker, R. & Sauer, U., Nov 2018, In: Molecular Systems Biology. 14, 11, e8623.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  28 Scopus citations

• Synthesis and Evaluation of¹¹ C-Labeled Triazolones as Probes for Imaging Fatty Acid Synthase Expression by Positron Emission Tomography

  Kelly, J. M., Jeitner, T. M., Waterhouse, N. N., Qu, W., Linstad, E. J., Samani, B., Williams, C., Nikolopoulou, A., Amor-Coarasa, A., Dimagno, S. G. & Babich, J. W., Mar 1 2022, In: Molecules. 27, 5, 1552.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Synthesis and evaluation of an acyl-chain unsaturated analog of the Th2 biasing, immunostimulatory glycolipid, OCH

  Velmourougane, G., Raju, R., Bricard, G., Im, J. S., Besra, G. S., Porcelli, S. A. & Howell, A. R., Jul 1 2009, In: Bioorganic and Medicinal Chemistry Letters. 19, 13, p. 3386-3388 3 p.

  Research output: Contribution to journal › Article › peer-review
  16 Scopus citations

• Synthesis and evaluation of antiproliferative activity of a geldanamycin-Herceptin(TM) immunoconjugate

  Mandler, R., Dadachova, E., Brechbiel, J. K., Waldmann, T. A. & Brechbiel, M. W., May 15 2000, In: Bioorganic and Medicinal Chemistry Letters. 10, 10, p. 1025-1028 4 p.

  Research output: Contribution to journal › Article › peer-review
  17 Scopus citations

• Synthesis and evaluation of new 4-phospho-D-erythronic acid derivatives as competitive inhibitors of spinach ribose-5-phosphate isomerase

  Burgos, E. & Salmon, L., Jan 19 2004, In: Tetrahedron Letters. 45, 4, p. 753-756 4 p.

  Research output: Contribution to journal › Article › peer-review
  11 Scopus citations

• Synthesis and evaluation of new antagonists of bacterial quorum sensing in Vibrio harveyi

  Peng, H., Cheng, Y., Ni, N., Li, M., Choudhary, G., Chou, H. T., Lu, C. D., Tai, P. C. & Wang, B., Sep 4 2009, In: ChemMedChem. 4, 9, p. 1457-1468 12 p.

  Research output: Contribution to journal › Article › peer-review
  46 Scopus citations

• Synthesis and evaluation of sphinganine analogues of KRN7000 and OCH

  Ndonye, R. M., Izmirian, D. P., Dunn, M. F., Yu, K. O. A., Porcelli, S. A., Khurana, A., Kronenberg, M., Richardson, S. K. & Howell, A. R., Dec 9 2005, In: Journal of Organic Chemistry. 70, 25, p. 10260-10270 11 p.

  Research output: Contribution to journal › Article › peer-review
  73 Scopus citations

• Synthesis and in vitro antimycobacterial activity of B-ring modified diaryl ether InhA inhibitors

  am Ende, C. W., Knudson, S. E., Liu, N., Childs, J., Sullivan, T. J., Boyne, M., Xu, H., Gegina, Y., Knudson, D. L., Johnson, F., Peloquin, C. A., Slayden, R. A. & Tonge, P. J., May 15 2008, In: Bioorganic and Medicinal Chemistry Letters. 18, 10, p. 3029-3033 5 p.

  Research output: Contribution to journal › Article › peer-review
  76 Scopus citations

• Synthesis and kinetic evaluation of 4-deoxy-4-phosphonomethyl-D- erythronate, the first hydrolytically stable and potent competitive inhibitor of ribose-5-phosphate isomerase

  Burgos, E. & Salmon, L., Apr 19 2004, In: Tetrahedron Letters. 45, 17, p. 3465-3469 5 p.

  Research output: Contribution to journal › Article › peer-review
  8 Scopus citations

• Synthesis and NMR characterization of the trypanosomatid metabolite, N ¹,N⁸-bis(glutathionyl)spermidine disulphide (trypanothione disulphide)

  Henderson, G. B., Glushka, J., Cowburn, D. & Cerami, A., 1990, In: Journal of the Chemical Society, Perkin Transactions 1. 4, p. 911-914 4 p.

  Research output: Contribution to journal › Article › peer-review
  22 Scopus citations

• Synthesis and pharmacological activity of 1,3,6-trisubstituted-4-oxo-1,4- dihydroquinoline-2-carboxylic acids as selective ET_A antagonists

  Patel, H. J., Olgun, N., Lengyel, I., Reznik, S. & Stephani, R. A., Nov 15 2010, In: Bioorganic and Medicinal Chemistry Letters. 20, 22, p. 6840-6844 5 p.

  Research output: Contribution to journal › Article › peer-review
  7 Scopus citations

• Synthesis and pre-clinical evaluation of a new class of high-affinity ¹⁸F-labeled PSMA ligands for detection of prostate cancer by PET imaging

  Kelly, J., Amor-Coarasa, A., Nikolopoulou, A., Kim, D., Williams, C., Ponnala, S. & Babich, J. W., Apr 1 2017, In: European Journal of Nuclear Medicine and Molecular Imaging. 44, 4, p. 647-661 15 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  43 Scopus citations

• Synthesis and preliminary biological evaluation of MMP inhibitor radiotracers [¹¹C]methyl-halo-CGS 27023A analogs, new potential PET breast cancer imaging agents

  Zheng, Q. H., Fei, X., Liu, X., Wang, J. Q., Bin Sun, H., Mock, B. H., Lee Stone, K., Martinez, T. D., Miller, K. D., Sledge, G. W. & Hutchins, G. D., Oct 2002, In: Nuclear Medicine and Biology. 29, 7, p. 761-770 10 p.

  Research output: Contribution to journal › Article › peer-review
  31 Scopus citations

• Synthesis and processing of precursor polypeptides to murine mammary tumor virus structural proteins

  Racevskis, J. & Sarkar, N. H., 1978, In: Journal of virology. 25, 1, p. 374-383 10 p.

  Research output: Contribution to journal › Article › peer-review

• Synthesis and processing of viral proteins in Friend erythroleukemia cell lines

  Racevskis, J. & Koch, G., Jun 15 1978, In: Virology. 87, 2, p. 354-365 12 p.

  Research output: Contribution to journal › Article › peer-review

• Synthesis and properties of 7-hydroxymethotrexate polyglutamyl derivatives in Ehrlich ascites tumor cells in vitro

  Fabre, G., Fabre, I., Matherly, L. H., Cano, J. P. & Goldman, I. D., 1984, In: Journal of Biological Chemistry. 259, 8, p. 5066-5072 7 p.

  Research output: Contribution to journal › Article › peer-review
  27 Scopus citations

• Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: Novel antibacterial agents against Mycobacterium tuberculosis

  Li, X., Liu, N., Zhang, H., Knudson, S. E., Slayden, R. A. & Tonge, P. J., Nov 1 2010, In: Bioorganic and Medicinal Chemistry Letters. 20, 21, p. 6306-6309 4 p.

  Research output: Contribution to journal › Article › peer-review
  89 Scopus citations

• Synthesis and screening of a small glycomimetic library for inhibitory activity on medically relevant galactoside-specific lectins in assays of increasing biorelevance

  André, S., Giguère, D., Dam, T. K., Brewer, F., Gabius, H. J. & Roy, R., Oct 1 2010, In: New Journal of Chemistry. 34, 10, p. 2229-2240 12 p.

  Research output: Contribution to journal › Article › peer-review
  40 Scopus citations

• Synthesis and secretion of a high molecular weight form of nerve growth factor by skeletal muscle cells in culture

  Murphy, R. A., Singer, R. H., Saide, J. D., Pantazis, N. J., Blanchard, M. H., Byron, K. S., Arnason, B. G. & Young, M., 1977, In: Unknown Journal. 74, 10, p. 4496-4500 5 p.

  Research output: Contribution to journal › Article › peer-review
  9 Scopus citations

• Synthesis and Structural Characterization of Ricin Inhibitors Targeting Ribosome Binding Using Fragment-Based Methods and Structure-Based Design

  Li, X. P., Harijan, R. K., Cao, B., Kahn, J. N., Pierce, M., Tsymbal, A. M., Roberge, J. Y., Augeri, D. & Tumer, N. E., Oct 28 2021, In: Journal of Medicinal Chemistry. 64, 20, p. 15334-15348 15 p.

  Research output: Contribution to journal › Article › peer-review
  2 Scopus citations

• Synthesis and structure of [Bp^But,Pri]₂Co: A bis(pyrazolyl)hydroborato cobalt(II) complex with trans [Co⋯H-B] interactions

  Ghosh, P., Bonanno, J. B. & Parkin, G., Jan 1 1998, In: Journal of the Chemical Society - Dalton Transactions. 17, p. 2779-2781 3 p.

  Research output: Contribution to journal › Article › peer-review
  9 Scopus citations

• Synthesis of (Z)-3,7-anhydro-1,2-dideoxy-2-deuterio-d-gluco-oct-2-enitol, a prochiral substrate for probing the catalytic functioning of glucosylases

  Weiser, W., Lehmann, J., Brewer, C. F. & Hehre, E. J., Dec 1 1988, In: Carbohydrate Research. 183, 2, p. 287-299 13 p.

  Research output: Contribution to journal › Article › peer-review
  11 Scopus citations

• Synthesis of [¹¹C]palmitic acid for PET imaging using a single molecular sieve 13X cartridge for reagent trapping, radiolabeling and selective purification

  Amor-Coarasa, A., Kelly, J. M. & Babich, J. W., Aug 1 2015, In: Nuclear Medicine and Biology. 42, 8, p. 685-690 6 p.

  Research output: Contribution to journal › Article › peer-review
  6 Scopus citations

• Synthesis of 1‐¹³C and 3‐¹³C isotopic isomers of aspartic and glutamic acids

  Fotadar, U. & Cowburn, D., 1983, In: Journal of Labelled Compounds and Radiopharmaceuticals. 20, 8, p. 1003-1009 7 p.

  Research output: Contribution to journal › Article › peer-review

• Synthesis of 4-phenoxybenzamide adenine dinucleotide as NAD analogue with inhibitory activity against enoyl-ACP reductase (InhA) of Mycobacterium tuberculosis

  Bonnac, L., Gao, G. Y., Chen, L., Felczak, K., Bennett, E. M., Xu, H., Kim, T. S., Liu, N., Oh, H. W., Tonge, P. J. & Pankiewicz, K. W., Aug 15 2007, In: Bioorganic and Medicinal Chemistry Letters. 17, 16, p. 4588-4591 4 p.

  Research output: Contribution to journal › Article › peer-review
  17 Scopus citations

• Synthesis of 5-benzyl and 5-benzyloxybenzyl 2,2'-anhydroudridines and related nucleoside analogs as inhibitors of uridine phosphorylase

  Chu, S. H., Weng, Z. Y., Chen, Z. H., Rowe, E. C., Chu, E., Naguib, F. N. M., el Kouni, M. H., Cha, S. & Chu, M. Y., Jan 2 1988, In: Nucleosides and Nucleotides. 7, 1, p. 91-102 12 p.

  Research output: Contribution to journal › Article › peer-review
  2 Scopus citations

• Synthesis of 5-deoxy-5-phospho-D-ribonohydroxamic acid: A new competitive and selective inhibitor of type B ribose-5-phosphate isomerase from Mycobacterium tuberculosis

  Burgos, E., Roos, A. K., Mowbray, S. L. & Salmon, L., May 23 2005, In: Tetrahedron Letters. 46, 21, p. 3691-3694 4 p.

  Research output: Contribution to journal › Article › peer-review
  9 Scopus citations

• Synthesis of 5-halogeno-6-amino-2'-deoxyuridines and their analogs as potential inhibitors of thymidine phosphorylase

  Pan, B. C., Chen, Z. H., Chu, E., WangChu, M. Y. & Chu, S. H., 1998, In: Nucleosides and Nucleotides. 17, 12, p. 2367-2382 16 p.

  Research output: Contribution to journal › Article › peer-review
  3 Scopus citations

• Synthesis of 5′-methylthio coformycins: Specific inhibitors for malarial adenosine deaminase

  Tyler, P. C., Taylor, E. A., Fröhlich, R. F. G. & Schramm, V. L., May 30 2007, In: Journal of the American Chemical Society. 129, 21, p. 6872-6879 8 p.

  Research output: Contribution to journal › Article › peer-review
  51 Scopus citations

• Synthesis of a carboxyl-terminal (constant region) fragment of the immunoglobin light chain by a mouse myeloma cell line

  Kuehl, W. M. & Scharff, M. D., Nov 5 1974, In: Journal of Molecular Biology. 89, 3, p. 409-412,IN1,413-421

  Research output: Contribution to journal › Article › peer-review
  3 Scopus citations

• Synthesis of all stereoisomers of KRN7000, the CD1d-binding NKT cell ligand

  Park, J. J., Lee, J. H., Ghosh, S. C., Bricard, G., Venkataswamy, M. M., Porcelli, S. A. & Chung, S. K., Jul 15 2008, In: Bioorganic and Medicinal Chemistry Letters. 18, 14, p. 3906-3909 4 p.

  Research output: Contribution to journal › Article › peer-review
  37 Scopus citations

• Synthesis of aminobenzyltriethylenetetraaminohexaacetic acid: Conjugation of the chelator to protein by an alkylamine linkage

  Bhargava, K. K., Zhang, Z. Y., Palestro, C. J. & Acharya, S. A., 1999, In: Journal of Protein Chemistry. 18, 7, p. 761-770 10 p.

  Research output: Contribution to journal › Article › peer-review

• Synthesis of aminobenzyltriethylenetetraaminohexaacetic acid: Conjugation of the chelator to protein by an alkylamine linkage

  Bhargava, K. K., Zhang, Z. Y., Palestro, C. J. & Acharya, S. A., 1999, In: Journal of Protein Chemistry. 18, 7, p. 761-770 10 p.

  Research output: Contribution to journal › Article › peer-review

• Synthesis of aminomethyl and amino analogs of 5‐benzylacyclouridine and 5‐benzyloxybenzylacyclouridine

  Chu, S. H., Chen, Z. H., Weng, Z. Y., Rowe, E. C., Chu, E. & Chu, MY. W., 1987, In: Journal of Heterocyclic Chemistry. 24, 4, p. 989-995 7 p.

  Research output: Contribution to journal › Article › peer-review

• Synthesis of a new 8-spin-labeled analog of adenosine 5'-phosphate and its interaction with AMP nucleosidase.

  DeWolf, W. E. & Schramm, V. L., Jul 25 1979, In: Journal of Biological Chemistry. 254, 14, p. 6215-6217 3 p.

  Research output: Contribution to journal › Article › peer-review