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  Structural Insight into AMPK Regulation: ADP Comes into Play

  Jin, X., Townley, R. & Shapiro, L., Oct 16 2007, In: Structure. 15, 10, p. 1285-1295 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  66 Scopus citations

• Structural insight into the interaction of proteins containing NPF, DPF, and GPF motifs with the C-terminal EH-domain of EHD1

  Kieken, F., Jović, M., Tonelli, M., Naslavsky, N., Caplan, S. & Sorgen, P. L., Dec 2009, In: Protein Science. 18, 12, p. 2471-2479 9 p.

  Research output: Contribution to journal › Article › peer-review
  20 Scopus citations

• Structural Insight into the Substrate Scope of Viperin and Viperin-like Enzymes from Three Domains of Life

  Lachowicz, J. C., Gizzi, A. S., Almo, S. C. & Grove, T. L., Jul 6 2021, In: Biochemistry. 60, 26, p. 2116-2129 14 p.

  Research output: Contribution to journal › Article › peer-review
  1 Scopus citations

• Structural Insights into Intermediate Steps in the Sir2 Deacetylation Reaction

  Hawse, W. F., Hoff, K. G., Fatkins, D. G., Daines, A., Zubkova, O. V., Schramm, V. L., Zheng, W. & Wolberger, C., Sep 10 2008, In: Structure. 16, 9, p. 1368-1377 10 p.

  Research output: Contribution to journal › Article › peer-review
  98 Scopus citations

• Structural insights into stereochemical inversion by diaminopimelate epimerase: An antibacterial drug target

  Pillai, B., Cherney, M. M., Diaper, C. M., Sutherland, A., Blanchard, J. S., Vederas, J. C. & James, M. M. G., Jun 6 2006, In: Proceedings of the National Academy of Sciences of the United States of America. 103, 23, p. 8668-8673 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  71 Scopus citations

• Structural insights into substrate and inhibitor binding sites in human indoleamine 2,3-dioxygenase

  Lewis-Ballester, A., Pham, K. N., Batabyal, D., Karkashon, S., Bonanno, J. B., Poulos, T. L. & Yeh, S. R., Dec 1 2017, In: Nature communications. 8, 1, 1693.

  Research output: Contribution to journal › Article › peer-review
  87 Scopus citations

• Structural Insights into the Recognition of Peroxisomal Targeting Signal 1 by Trypanosoma brucei Peroxin 5

  Sampathkumar, P., Roach, C., Michels, P. A. M. & Hol, W. G. J., Sep 12 2008, In: Journal of Molecular Biology. 381, 4, p. 867-880 14 p.

  Research output: Contribution to journal › Article › peer-review
  38 Scopus citations

• Structural Insights into Thioether Bond Formation in the Biosynthesis of Sactipeptides

  Grove, T. L., Himes, P. M., Hwang, S., Yumerefendi, H., Bonanno, J. B., Kuhlman, B., Almo, S. C. & Bowers, A. A., Aug 30 2017, In: Journal of the American Chemical Society. 139, 34, p. 11734-11744 11 p.

  Research output: Contribution to journal › Article › peer-review
  73 Scopus citations

• Structural insights into triglyceride storage mediated by fat storage-inducing transmembrane (FIT) protein 2

  Gross, D. A., Snapp, E. L. & Silver, D. L., 2010, In: PloS one. 5, 5, e10796.

  Research output: Contribution to journal › Article › peer-review
  42 Scopus citations

• Structural Insights to How Mammalian Capping Enzyme Reads the CTD Code

  Ghosh, A., Shuman, S. & Lima, C. D., Jul 22 2011, In: Molecular Cell. 43, 2, p. 299-310 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  66 Scopus citations

• Structural investigations of the hemoglobin of the cyanobacterium Synechocystis PCC6803 reveal a unique distal heme pocket

  Couture, M., Das, T. K., Savard, P. Y., Ouellet, Y., Wittenberg, J. B., Wittenberg, B. A., Rousseau, D. L. & Guertin, M., 2000, In: European Journal of Biochemistry. 267, 15, p. 4770-4780 11 p.

  Research output: Contribution to journal › Article › peer-review
  91 Scopus citations

• Structurally diverse dendritic libraries: A highly efficient functionalization approach using click chemistry

  Malkoch, M., Schleicher, K., Drockenmuller, E., Hawker, C. J., Russell, T. P., Wu, P. & Fokin, V. V., May 3 2005, In: Macromolecules. 38, 9, p. 3663-3678 16 p.

  Research output: Contribution to journal › Article › peer-review
  369 Scopus citations

• Structural mechanisms of allostery and autoinhibition in JNK family kinases

  Laughlin, J. D., Nwachukwu, J. C., Figuera-Losada, M., Cherry, L., Nettles, K. W. & Lograsso, P. V., Dec 5 2012, In: Structure. 20, 12, p. 2174-2184 11 p.

  Research output: Contribution to journal › Article › peer-review
  32 Scopus citations

• Structural model for tubulin recognition and deformation by kinesin-13 microtubule depolymerases

  Asenjo, A. B., Chatterjee, C., Tan, D., DePaoli, V., Rice, W. J., Diaz-Avalos, R., Silvestry, M. & Sosa, H., 2013, In: Cell Reports. 3, 3, p. 759-768 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  45 Scopus citations

• Structural neuroimaging biomarkers for obsessive-compulsive disorder in the ENIGMA-OCD consortium: medication matters

  ENIGMA OCD Working Group, Dec 1 2020, In: Translational psychiatry. 10, 1, 342.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  11 Scopus citations

• Structural order in Pannexin 1 cytoplasmic domains

  Spagnol, G., Sorgen, P. L. & Spray, D. C., 2014, In: Channels. 8, 2, p. 157-166 10 p.

  Research output: Contribution to journal › Article › peer-review
  9 Scopus citations

• Structural perturbation of superfolder GFP in the presence of guanidine thiocyanate

  Stepanenko, O. V., Stepanenko, O. V., Kuznetsova, I. M., Verkhusha, V. V. & Turoverov, K. K., 2012, In: Spectroscopy (New York). 27, 5-6, p. 381-386 6 p.

  Research output: Contribution to journal › Article › peer-review
  1 Scopus citations

• Structural perturbations induced by the α-anomer of the aflatoxin B₁ formamidopyrimidine adduct in duplex and single-strand DNA

  Brown, K. L., Voehler, M. W., Magee, S. M., Harris, C. M., Harris, T. M. & Stone, M. P., 2009, In: Journal of the American Chemical Society. 131, 44, p. 16096-16107 12 p.

  Research output: Contribution to journal › Article › peer-review
  21 Scopus citations

• Structural Properties and Mechanisms that Govern Association of C Kinase Adapter 1 with Protein Kinase C3 and the Cell Periphery

  Zhang, L., Wu, S. L. & Rubin, C. S., Mar 30 2001, In: Journal of Biological Chemistry. 276, 13, p. 10476-10484 9 p.

  Research output: Contribution to journal › Article › peer-review
  6 Scopus citations

• Structural properties of the Caenorhabditis elegans neuronal network

  Varshney, L. R., Chen, B. L., Paniagua, E., Hall, D. H. & Chklovskii, D. B., Feb 2011, In: PLoS Computational Biology. 7, 2, e1001066.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  486 Scopus citations

• Structural rationale for the affinity of pico- and femtomolar transition state analogues of Escherichia coli 5′-methylthioadenosine/S- adenosylhomocysteine nucleosidase

  Lee, J. E., Singh, V., Evans, G. B., Tyler, P. C., Furneax, R. H., Cornell, K. A., Riscoe, M. K., Schramm, V. L. & Howell, P. L., May 6 2005, In: Journal of Biological Chemistry. 280, 18, p. 18274-18282 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  73 Scopus citations

• Structural rearrangement of SULT2A1: Effects on dehydroepiandrosterone and raloxifene sulfation

  Cook, I. T., Falany, C. N., Leyh, T. S., Kadlubar, S. A. & Falany, C. N., 2010, In: Hormone Molecular Biology and Clinical Investigation. 1, 2, p. 81-87 7 p.

  Research output: Contribution to journal › Article › peer-review
  33 Scopus citations

• Structural refinement of the tubulin ligand (+)-Discodermolide to attenuate chemotherapy-mediated senescence

  Guo, B., Rodriguez-Gabin, A., Prota, A. E., Mühlethaler, T., Zhang, N., Ye, K., Steinmetz, M. O., Horwitz, S. B., Smith, A. B. & McDaid, H. M., 2020, In: Molecular Pharmacology. 98, 2, p. 156-167 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  3 Scopus citations

• Structural Reorganization of Proteins Revealed by Radiolysis and Mass Spectrometry: G-Actin Solution Structure is Divalent Cation Dependent

  Guan, J. Q., Almo, S. C., Reisler, E. & Chance, M. R., Oct 21 2003, In: Biochemistry. 42, 41, p. 11992-12000 9 p.

  Research output: Contribution to journal › Article › peer-review
  48 Scopus citations

• Structural reorganization of the antigen-binding groove of human CD1b for presentation of mycobacterial sulfoglycolipids

  Garcia-Alles, L. F., Collmann, A., Versluis, C., Lindner, B., Guiard, J., Maveyraud, L., Huca, E., Im, J. S., Sansano, S., Brando, T., Julien, S., Prandi, J., Gilleron, M., Porcelli, S. A., De La Salle, H., Heck, A. J. R., Mori, L., Puzo, G., Mourey, L. & De Libero, G., Oct 25 2011, In: Proceedings of the National Academy of Sciences of the United States of America. 108, 43, p. 17755-17760 6 p.

  Research output: Contribution to journal › Article › peer-review
  41 Scopus citations

• Structural Requirements for Bacterial Expression of Stable, Enzymatically Active Fusion Proteins Containing the Human Immunodeficiency Virus Reverse Transcriptase

  Tanese, N., Prasad, V. R. & Goff, S. P., Jul 1988, In: DNA. 7, 6, p. 407-416 10 p.

  Research output: Contribution to journal › Article › peer-review
  21 Scopus citations

• Structural requirements for glycolipid antigen recognition by CD1b- restricted T cells

  Moody, D. B., Reinhold, B. B., Guy, M. R., Beckman, E. M., Frederique, D. E., Furlong, S. T., Ye, S., Reinhold, V. N., Sieling, P. A., Modlin, R. L., Besra, G. S. & Porcelli, S. A., Oct 10 1997, In: Science. 278, 5336, p. 283-286 4 p.

  Research output: Contribution to journal › Article › peer-review
  377 Scopus citations

• Structural requirements of immunoglobulin G for binding to the FC(γ) receptors of the human tumor cell lines U937, HL-60, ML-1, and K562

  McCool, D., Birshtein, B. K. & Painter, R. H., Dec 1 1985, In: Journal of Immunology. 135, 3, p. 1975-1980 6 p.

  Research output: Contribution to journal › Article › peer-review
  20 Scopus citations

• Structural segregation of gut microbiota between colorectal cancer patients and healthy volunteers

  Wang, T., Cai, G., Qiu, Y., Fei, N., Zhang, M., Pang, X., Jia, W., Cai, S. & Zhao, L., Feb 2012, In: ISME Journal. 6, 2, p. 320-329 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  704 Scopus citations

• Structural shifts of gut microbiota as surrogate endpoints for monitoring host health changes induced by carcinogen exposure

  Wei, H., Dong, L., Wang, T., Zhang, M., Hua, W., Zhang, C., Pang, X., Chen, M., Su, M., Qiu, Y., Zhou, M., Yang, S., Chen, Z., Rantalainen, M., Nicholson, J. K., Jia, W., Wu, D. & Zhao, L., Sep 2010, In: FEMS Microbiology Ecology. 73, 3, p. 577-586 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  43 Scopus citations

• Structural social support and cardiovascular disease risk factors in Hispanic/Latino adults with diabetes: results from the Hispanic Community Health Study/Study of Latinos (HCHS/SOL)

  Hernandez, R., Carnethon, M., Giachello, A. L., Penedo, F. J., Wu, D., Birnbaum-Weitzman, O., Giacinto, R. E., Gallo, L. C., Isasi, C. R., Schneiderman, N., Teng, Y., Zeng, D. & Daviglus, M. L., Oct 3 2018, In: Ethnicity and Health. 23, 7, p. 737-751 15 p.

  Research output: Contribution to journal › Article › peer-review
  7 Scopus citations

• Structural studies of 2.5 S mouse submaxillary gland nerve growth factor.

  Angeletti, R. H., Frazier, W. A. & Bradshaw, R. A., 1972, In: Advances in experimental medicine and biology. 32, p. 99-106 8 p.

  Research output: Contribution to journal › Article › peer-review
  1 Scopus citations

• Structural studies of human purine nucleoside phosphorylase: Towards a new specific empirical scoring function

  Timmers, L. F. S. M., Caceres, R. A., Vivan, A. L., Gava, L. M., Dias, R., Ducati, R. G., Basso, L. A., Santos, D. S. & de Azevedo, W. F., Nov 1 2008, In: Archives of Biochemistry and Biophysics. 479, 1, p. 28-38 11 p.

  Research output: Contribution to journal › Article › peer-review
  33 Scopus citations

• Structural studies of N-terminal mutants of Connexin 32 using ¹H NMR spectroscopy

  Kalmatsky, B. D., Batir, Y., Bargiello, T. A. & Dowd, T. L., Oct 1 2012, In: Archives of Biochemistry and Biophysics. 526, 1, p. 1-8 8 p.

  Research output: Contribution to journal › Article › peer-review
  13 Scopus citations

• Structural Studies of Ribonuclease. II. Deuterium Exchange Studies of Two Crystalline Forms of Ribonuclease1,2

  Schildkraut, C. L. & Scheraga, H. A., Jan 1 1960, In: Journal of the American Chemical Society. 82, 1, p. 58-62 5 p.

  Research output: Contribution to journal › Article › peer-review
  4 Scopus citations

• Structural studies of the [tris(midazolyl)phosphine]metal nitrate complexes {[Pim(Pr(i),Bu(t))]M(NO₃)}⁺ (M = Co, Cu, Zn, Cd, Hg): Comparison of nitrate-binding modes in synthetic analogues of carbonic anhydrase

  Kimblin, C., Murphy, V. J., Hascall, T., Bridgewater, B. M., Bonanno, J. B. & Parkin, G., Mar 6 2000, In: Inorganic Chemistry. 39, 5, p. 967-974 8 p.

  Research output: Contribution to journal › Article › peer-review
  81 Scopus citations

• Structural studies of the nedd4WWDomains and their selectivity for the connexin43 (Cx43) carboxyl trerminus

  Spagnol, G., Kieken, F., Kopanic, J. L., Li, H., Zach, S., Stauch, K. L., Grosely, R. & Sorgen, P. L., Apr 1 2016, In: Journal of Biological Chemistry. 291, 14, p. 7637-7650 14 p.

  Research output: Contribution to journal › Article › peer-review
  34 Scopus citations

• Structural studies of the N-terminus of Connexin 32 using ¹H NMR spectroscopy

  Kalmatsky, B. D., Bhagan, S., Tang, Q., Bargiello, T. A. & Dowd, T. L., Oct 1 2009, In: Archives of Biochemistry and Biophysics. 490, 1, p. 9-16 8 p.

  Research output: Contribution to journal › Article › peer-review
  19 Scopus citations

• Structural Studies of Vγ2Vδ2 T Cell Phosphoantigens

  Zhang, Y., Song, Y., Yin, F., Broderick, E., Siegel, K., Goddard, A., Nieves, E., Pasa-Tolic, L., Tanaka, Y., Wang, H., Morita, C. T. & Oldfield, E., Sep 2006, In: Chemistry and Biology. 13, 9, p. 985-992 8 p.

  Research output: Contribution to journal › Article › peer-review
  22 Scopus citations

• Structural Study of a Flexible Active Site Loop in Human Indoleamine 2,3-Dioxygenase and Its Functional Implications

  Álvarez, L., Lewis-Ballester, A., Roitberg, A., Estrin, D. A., Yeh, S. R., Marti, M. A. & Capece, L., May 17 2016, In: Biochemistry. 55, 19, p. 2785-2793 9 p.

  Research output: Contribution to journal › Article › peer-review
  20 Scopus citations

• Structural symmetry: The three-dimensional structure of Haemophilus influenzae diaminopimelate epimerase

  Cirilli, M., Zheng, R., Scapin, G. & Blanchard, J. S., Nov 24 1998, In: Biochemistry. 37, 47, p. 16452-16458 7 p.

  Research output: Contribution to journal › Article › peer-review
  70 Scopus citations

• Structural transformations in the dynamics of Michaelis complex formation in lactate dehydrogenase

  McClendon, S., Vu, D. M., Clinch, K., Callender, R. & Dyer, R. B., Jul 2005, In: Biophysical journal. 89, 1, p. L07-L09

  Research output: Contribution to journal › Article › peer-review

  Open Access
  24 Scopus citations

• Structural Underpinnings of Nitrogen Regulation by the Prototypical Nitrogen-Responsive Transcriptional Factor NrpR

  Wisedchaisri, G., Dranow, D. M., Lie, T. J., Bonanno, J. B., Patskovsky, Y., Ozyurt, S. A., Sauder, J. M., Almo, S. C., Wasserman, S. R., Burley, S. K., Leigh, J. A. & Gonen, T., Nov 10 2010, In: Structure. 18, 11, p. 1512-1521 10 p.

  Research output: Contribution to journal › Article › peer-review
  7 Scopus citations

• Structural visualization of the p53/RNA polymerase II assembly

  Singh, S. K., Qiao, Z., Song, L., Jani, V., Rice, W., Eng, E., Coleman, R. A. & Liu, W. L., Nov 15 2016, In: Genes and Development. 30, 22, p. 2527-2537 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  9 Scopus citations

• Structure, dynamics, evolution, and function of a major scaffold component in the nuclear pore complex

  Sampathkumar, P., Kim, S. J., Upla, P., Rice, W. J., Phillips, J., Timney, B. L., Pieper, U., Bonanno, J. B., Fernandez-Martinez, J., Hakhverdyan, Z., Ketaren, N. E., Matsui, T., Weiss, T. M., Stokes, D. L., Sauder, J. M., Burley, S. K., Sali, A., Rout, M. P. & Almo, S. C., Apr 2 2013, In: Structure. 21, 4, p. 560-571 12 p.

  Research output: Contribution to journal › Article › peer-review
  45 Scopus citations

• Structure, Evolutionary Conservation, and Conformational Dynamics of Homo sapiens Fascin-1, an F-actin Crosslinking Protein

  Sedeh, R. S., Fedorov, A. A., Fedorov, E. V., Ono, S., Matsumura, F., Almo, S. C. & Bathe, M., Jul 2010, In: Journal of Molecular Biology. 400, 3, p. 589-604 16 p.

  Research output: Contribution to journal › Article › peer-review
  59 Scopus citations

• Structure, expression, and properties of an atypical protein kinase C (PKC3) from Caenorhabditis elegans. PKC3 is required for the normal progression of embryogenesis and viability of the organism

  Wu, S. L., Staudinger, J., Olson, E. N. & Rubin, C. S., Jan 9 1998, In: Journal of Biological Chemistry. 273, 2, p. 1130-1143 14 p.

  Research output: Contribution to journal › Article › peer-review
  33 Scopus citations

• Structure, expression, and regulation of the kilC operon of promiscuous IncPα plasmids

  Larsen, M. H. & Figurski, D. H., 1994, In: Journal of Bacteriology. 176, 16, p. 5022-5032 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  45 Scopus citations

• Structure, Function, and Applications of the Georgetown–Einstein (GE) Breast Cancer Simulation Model

  Schechter, C. B., Near, A. M., Jayasekera, J., Chandler, Y. & Mandelblatt, J. S., Apr 1 2018, In: Medical Decision Making. 38, 1_suppl, p. 66S-77S

  Research output: Contribution to journal › Article › peer-review
  20 Scopus citations

• Structure, inhibitor, and regulatory mechanism of Lyp, a lymphoid-specific tyrosine phosphatase implicated in autoimmune diseases

  Yu, X., Sun, J. P., He, Y., Guo, X., Liu, S., Zhou, B., Hudmon, A. & Zhang, Z. Y., Dec 11 2007, In: Proceedings of the National Academy of Sciences of the United States of America. 104, 50, p. 19767-19772 6 p.

  Research output: Contribution to journal › Article › peer-review
  120 Scopus citations