Find Research Outputs

2019

Sensitization of colorectal cancer to irinotecan therapy by PARP inhibitor rucaparib

Augustine, T. A., Maitra, R., Zhang, J., Nayak, J. & Goel, S., Jan 1 2019, (Accepted/In press) In : Investigational New Drugs.

Research output: Contribution to journalArticle

irinotecan
Colorectal Neoplasms
Microsatellite Repeats
Apoptosis
HCT116 Cells
Left ventricular assist devices
Heart-Assist Devices
Hepatitis C Antibodies
Viruses
Antibodies

Sex-Specific Differences in Redox Homeostasis in Brain Norm and Disease

Ruszkiewicz, J. A., Miranda-Vizuete, A., Tinkov, A. A., Skalnaya, M. G., Skalny, A. V., Tsatsakis, A. & Aschner, M., Jan 1 2019, (Accepted/In press) In : Journal of Molecular Neuroscience.

Research output: Contribution to journalArticle

Brain Diseases
Sex Characteristics
Oxidation-Reduction
Homeostasis
Brain

Sexual Partner Characteristics, Relationship Type, and HIV Risk Among a Community Venue–Based Sample of Urban Adolescent and Young Adult Men Who Have Sex With Men

The Adolescent Medicine Trials Network for HIV/AIDS Interventions, Mar 1 2019, In : Youth and Society. 51, 2, p. 219-246 28 p.

Research output: Contribution to journalArticle

young adult
adolescent
community
counseling
alcohol

Signal Transduction, Ageing and Disease

Zhang, L., Yousefzadeh, M. J., Suh, Y., Niedernhofer, L. J. & Robbins, P. D., Jan 1 2019, In : Sub-cellular biochemistry. 91, p. 227-247 21 p.

Research output: Contribution to journalArticle

Signal transduction
Signal Transduction
Aging of materials
Tissue homeostasis
Sirtuins

Significant racial differences in the incidence and behavior of the follicular variant of papillary thyroid carcinoma

Mehta, V., Ow, T. J., Kim, S., Tharakan, T., Schiff, B. A., Smith, R. V. & In, H., Jan 1 2019, (Accepted/In press) In : Head and Neck.

Research output: Contribution to journalArticle

Hispanic Americans
Incidence
Lymph Nodes
Neoplasm Metastasis
Neoplasms

Single dose of a rVSV-based vaccine elicits complete protection against severe fever with thrombocytopenia syndrome virus

Dong, F., Li, D., Wen, D., Li, S., Zhao, C., Qi, Y., Jangra, R., Wu, C., Xia, D., Zhang, X., Deng, F., Chandran, K., Zou, Z., Yuan, F. & Zheng, A., Dec 1 2019, In : npj Vaccines. 4, 1, 5.

Research output: Contribution to journalArticle

Vesicular Stomatitis
Thrombocytopenia
Phlebovirus
Fever
Vaccines

Sinus Surgery Is Associated with a Decrease in Aspirin-Induced Reaction Severity in Patients with Aspirin Exacerbated Respiratory Disease

Jerschow, E., Edin, M. L., Chi, Y., Hurst, B., Abuzeid, W. M., Akbar, N. A., Gibber, M. J., Fried, M. P., Han, W., Pelletier, T., Ren, Z., Keskin, T., Gottlieb, G. R., Lih, F. B., Gruzdev, A., Bradbury, J. A., Schuster, V. L., Spivack, S. D., Rosenstreich, D. L. & Zeldin, D. C., Jan 1 2019, (Accepted/In press) In : Journal of Allergy and Clinical Immunology: In Practice.

Research output: Contribution to journalArticle

Aspirin
Eicosanoids
Creatinine
Hypersensitivity
Urine

SIU–ICUD consultation on bladder cancer: treatment of muscle-invasive bladder cancer

Leow, J. J., Bedke, J., Chamie, K., Collins, J. W., Daneshmand, S., Grivas, P., Heidenreich, A., Messing, E. M., Royce, T. J., Sankin, A. I., Schoenberg, M. P., Shipley, W. U., Villers, A., Efstathiou, J. A., Bellmunt, J. & Stenzl, A., Jan 23 2019, In : World Journal of Urology. 37, 1, p. 61-83 23 p.

Research output: Contribution to journalArticle

Muscle Neoplasms
Urologic Diseases
Urinary Bladder Neoplasms
Cystectomy
Referral and Consultation

SLC30A10 transporter in the digestive system regulates brain manganese under basal conditions while brain SLC30A10 protects against neurotoxicity

Taylor, C. A., Hutchens, S., Liu, C., Jursa, T., Shawlot, W., Aschner, M., Smith, D. R. & Mukhopadhyay, S., Jan 1 2019, In : Journal of Biological Chemistry. 294, 6, p. 1860-1876 17 p.

Research output: Contribution to journalArticle

Digestive system
Digestive System
Manganese
Brain
Liver
Developmental Disabilities
Autistic Disorder
Sleep
Interviews
Checklist
multiplexing
Multiplexing
Biliverdine
Infrared radiation
proteins
1 Citation (Scopus)

Small-molecule allosteric inhibitors of BAX

Garner, T. P., Amgalan, D., Reyna, D. E., Li, S., Kitsis, R. N. & Gavathiotis, E., Jan 1 2019, In : Nature Chemical Biology.

Research output: Contribution to journalArticle

Cell Death
Mitochondrial Membranes
Hydrogen Bonding
Pharmacology
Proteins
1 Citation (Scopus)

Snapshot of an oxygen intermediate in the catalytic reaction of cytochrome c oxidase

Ishigami, I., Lewis-Ballester, A., Echelmeier, A., Brehm, G., Zatsepin, N. A., Grant, T. D., Coe, J. D., Lisova, S., Nelson, G., Zhang, S., Dobson, Z. F., Boutet, S., Sierra, R. G., Batyuk, A., Fromme, P., Fromme, R., Spence, J. C. H., Ros, A., Yeh, S-R. & Rousseau, D. L., Feb 26 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 9, p. 3572-3577 6 p.

Research output: Contribution to journalArticle

Electron Transport Complex IV
Oxygen
Protons
Protein Conformation
Crystallography

Social contexts as mediator of risk behaviors in Rwandan men who have sex with men (MSM): Implications for HIV and STI transmission

Adedimeji, A. A., Sinayobye, J. D. A., Asiimwe-Kateera, B., Chaudhry, J., Buzinge, L., Gitembagara, A., Murenzi, G., Mugenzi, P., Patel, V. V., Castle, P. E., Mutesa, L., Palefsky, J. & Anastos, K., Jan 1 2019, In : PLoS One. 14, 1, e0211099.

Research output: Contribution to journalArticle

risk behavior
sexual behavior
Sexually Transmitted Diseases
Risk-Taking
HIV

Splicing and neurodegeneration: Insights and mechanisms

Nik, S. & Bowman, T. V., Jan 1 2019, In : Wiley Interdisciplinary Reviews: RNA. e1532.

Research output: Contribution to journalReview article

Alternative Splicing
RNA
Spliceosomes
RNA Splicing
Introns

Statin exposure is not associated with reduced prevalence of colorectal neoplasia in patients with inflammatory bowel disease

Shah, S. C., Glass, J., Giustino, G., Ten Hove, J. R., Castaneda, D., Torres, J., Kumar, A., Elman, J., Ullman, T. A. & Itzkowitz, S. H., Jan 1 2019, In : Gut and Liver. 13, 1, p. 54-61 8 p.

Research output: Contribution to journalArticle

Hydroxymethylglutaryl-CoA Reductase Inhibitors
Inflammatory Bowel Diseases
Colorectal Neoplasms
Neoplasms
Colonoscopy

Stress-Induced Cardiomyopathy

Zhang, L. & Pina, I. L., Jan 1 2019, In : Heart Failure Clinics. 15, 1, p. 41-53 13 p.

Research output: Contribution to journalReview article

Takotsubo Cardiomyopathy
Ventricular Outflow Obstruction
Cardiogenic Shock
Acute Coronary Syndrome
Heart Ventricles

Structural basis of broad ebolavirus neutralization by a human survivor antibody

West, B. R., Wec, A. Z., Moyer, C. L., Fusco, M. L., Ilinykh, P. A., Huang, K., Wirchnianski, A. S., James, R. M., Herbert, A. S., Hui, S., Goodwin, E., Howell, K. A., Kailasan, S., Aman, M. J., Walker, L. M., Dye, J. M., Bukreyev, A., Chandran, K. & Saphire, E. O., Mar 1 2019, In : Nature Structural and Molecular Biology. 26, 3, p. 204-212 9 p.

Research output: Contribution to journalArticle

Ebolavirus
Sudan
Viruses
Antibodies
Epitopes

Subnanometer cobalt oxide clusters as selective low temperature oxidative dehydrogenation catalysts

Lee, S., Halder, A., Ferguson, G. A., Seifert, S., Winans, R. E., Teschner, D., Schlögl, R., Papaefthimiou, V., Greeley, J., Curtiss, L. A. & Vajda, S., Dec 1 2019, In : Nature Communications. 10, 1, 954.

Research output: Contribution to journalArticle

cobalt oxides
Dehydrogenation
dehydrogenation
catalysts
Catalysts
Dementia
Cognition
Alzheimer Disease
Independent Living
Geography

Successful Return to Sport Following Distal Femoral Varus Osteotomy

Voleti, P. B., Wu, I. T., Degen, R. M., Tetreault, D. M., Krych, A. J. & Williams, R. J., Jan 1 2019, In : Cartilage. 10, 1, p. 19-25 7 p.

Research output: Contribution to journalReview article

Osteotomy
Thigh
Sports
Knee
Athletes
Mitral Valve Insufficiency
Coronary Artery Bypass

Surrogates' and researchers' assessments of prehospital frailty in critically ill older adults

Hope, A. A., Munoz, M., Hsieh, S. J. & Gong, M. N., Mar 1 2019, In : American Journal of Critical Care. 28, 2, p. 117-123 7 p.

Research output: Contribution to journalArticle

Open Access
Critical Illness
Research Personnel
Intensive Care Units
Critical Care
Observational Studies

Targeted sequencing to discover germline variants in the BRCA1 and BRCA2 genes in a Russian population and their association with breast cancer risk

Solodskikh, S. A., Panevina, A. V., Gryaznova, M. V., Gureev, A. P., Serzhantova, O. V., Mikhailov, A. A., Maslov, A. & Popov, V. N., Jan 1 2019, In : Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. 813, p. 51-57 7 p.

Research output: Contribution to journalArticle

BRCA2 Gene
BRCA1 Gene
Breast Neoplasms
Population
Neoplasms

Targeting mitochondria to oppose the progression of nonalcoholic fatty liver disease

Grattagliano, I., Montezinho, L. P., Oliveira, P. J., Frühbeck, G., Gómez-Ambrosi, J., Montecucco, F., Carbone, F., Wieckowski, M. R., Wang, D. Q. H. & Portincasa, P., Feb 1 2019, In : Biochemical Pharmacology. 160, p. 34-45 12 p.

Research output: Contribution to journalReview article

Mitochondria
Liver
Fatty Liver
Liver Cirrhosis
Hepatocytes

Tenofovir disoproxil fumarate initiation and changes in urinary biomarker concentrations among HIV-infected men and women

Zhang, W. R., Scherzer, R., Estrella, M. M., Ascher, S. B., Muiru, A., Jotwani, V., Grunfeld, C., Parikh, C. R., Gustafson, D., Kassaye, S., Sharma, A., Cohen, M., Tien, P. C., Ng, D. K., Palella, F. J., Witt, M. D., Ho, K. & Shlipak, M. G., Mar 15 2019, In : AIDS (London, England). 33, 4, p. 723-733 11 p.

Research output: Contribution to journalArticle

Tenofovir
Biomarkers
HIV
Confidence Intervals
Kidney

The alphavirus E2 membrane-proximal domain impacts capsid interaction and glycoprotein lattice formation

Byrd, E. A. & Kielian, M., Feb 1 2019, In : Journal of Virology. 93, 4, e0188118.

Research output: Contribution to journalArticle

Alphavirus
capsid
Capsid
Capsid Proteins
coat proteins

The burden of cervical cancer in Vietnam: Synthesis of the evidence

Thi Nguyen, D. N., Simms, K., Vu Nguyen, H. Q., Van Tran, T., Nguyen, N. H., LaMontagne, D. S., Castle, P. E. & Canfell, K., Apr 1 2019, In : Cancer Epidemiology. 59, p. 83-103 21 p.

Research output: Contribution to journalReview article

Vietnam
Uterine Cervical Neoplasms
Registries
Urban Population
Mortality
Multiple Sequence Alignment
Sequence Alignment
Sequence Homology
Conservation
Protein

The cost-effectiveness of implementing HPV testing for cervical cancer screening in El Salvador

Campos, N. G., Maza, M., Alfaro, K., Gage, J. C., Castle, P. E., Felix, J. C., Masch, R., Cremer, M. & Kim, J. J., Apr 1 2019, In : International Journal of Gynecology and Obstetrics. 145, 1, p. 40-46 7 p.

Research output: Contribution to journalArticle

Open Access
El Salvador
Early Detection of Cancer
Uterine Cervical Neoplasms
Cost-Benefit Analysis
Cryotherapy

The design and conduct of Project RedDE: A cluster-randomized trial to reduce diagnostic errors in pediatric primary care

Bundy, D. G., Singh, H., Stein, R. E. K., Brady, T. M., Lehmann, C. U., Heo, M., O'Donnell, H. C., Rice-Conboy, E. & Rinke, M. L., Jan 1 2019, In : Clinical Trials.

Research output: Contribution to journalArticle

Quality Improvement
Diagnostic Errors
Primary Health Care
Pediatrics
Root Cause Analysis

The effect of polypharmacy on prefrontal cortex activation during single and dual task walking in community dwelling older adults

George, C. J., Verghese, J., Izzetoglu, M., Wang, C. & Holtzer, R., Jan 1 2019, In : Pharmacological Research. 139, p. 113-119 7 p.

Research output: Contribution to journalArticle

Independent Living
Polypharmacy
Prefrontal Cortex
Walking
Locomotion

The emerging roles of macrophages in cancer metastasis and response to chemotherapy

Sanchez, L. R., Borriello, L., Entenberg, D. R., Condeelis, J. S., Oktay, M. H. & Karagiannis, G. S., Jan 1 2019, In : Journal of Leukocyte Biology.

Research output: Contribution to journalReview article

Macrophages
Neoplasm Metastasis
Drug Therapy
Neoplasms
Tumor Microenvironment

The Functional Heterogeneity of Resident Cardiac Macrophages in Myocardial InjuryCCR2+ Cells Promote Inflammation, Whereas CCR2- Cells Protect

Chen, B., Brickshawana, A. & Frangogiannis, N. G., Jan 18 2019, In : Circulation Research. 124, 2, p. 183-185 3 p.

Research output: Contribution to journalEditorial

Chemokines
Macrophages
Myocardial Infarction
Cytokines
Inflammation

The Impact of Past and Current Alcohol Consumption Patterns on Progression of Carotid Intima-Media Thickness Among Women and Men Living with HIV Infection

Chichetto, N. E., Plankey, M. W., Abraham, A. G., Sheps, D. S., Ennis, N., Chen, X., Weber, K. M., Shoptaw, S., Kaplan, R. C., Post, W. S. & Cook, R. L., Jan 1 2019, In : Alcoholism: Clinical and Experimental Research.

Research output: Contribution to journalArticle

Carotid Intima-Media Thickness
Alcohol Drinking
HIV Infections
Alcohols
HIV

The macroH2A1.2 histone variant links ATRX loss to alternative telomere lengthening

Kim, J., Sun, C., Tran, A. D., Chin, P. J., Ruiz, P. D., Wang, K., Gibbons, R. J., Gamble, M. J., Liu, Y. & Oberdoerffer, P., Mar 1 2019, In : Nature Structural and Molecular Biology. 26, 3, p. 213-219 7 p.

Research output: Contribution to journalArticle

Telomere Homeostasis
Histones
Telomere
Homologous Recombination
Epigenomics

The relationship of anxiety and smoking behaviors to medication adherence among cigarette smokers living with HIV

Esan, H., Shuter, J. & Weinberger, A. H., Mar 1 2019, In : Addictive Behaviors. 90, p. 301-305 5 p.

Research output: Contribution to journalArticle

Medication Adherence
Tobacco Products
Anxiety
Smoking
HIV

Thermal burn on denervated skin that developed after sun exposure on black clothing

Schneider, A., Ferastraoaru, D. E. & Rosenstreich, D. L., Mar 1 2019, In : JAAD Case Reports. 5, 3, p. 242-244 3 p.

Research output: Contribution to journalArticle

Open Access
Clothing
Thoracic Wall
Solar System
Hot Temperature
Skin
2 Citations (Scopus)

Thermal stress induces glycolytic beige fat formation via a myogenic state

Chen, Y., Ikeda, K., Yoneshiro, T., Scaramozza, A., Tajima, K., Wang, Q., Kim, K., Shinoda, K., Sponton, C. H., Brown, Z., Brack, A. & Kajimura, S., Jan 10 2019, In : Nature. 565, 7738, p. 180-185 6 p.

Research output: Contribution to journalArticle

Hot Temperature
Cues
GA-Binding Protein Transcription Factor
Acclimatization
Adipocytes

Thermo reversible hydrogel based delivery of mitomycin C (UGN-101) for treatment of upper tract urothelial carcinoma (UTUC)

Kleinmann, N., Wirth, G., Lin, J. S., Matin, S. F., Nativ, O., Mayer, G., Witjes, J. A., Shvero, A., Chamie, K., Pantuck, A. J., Smith, A., Schoenberg, M. P., Malchi, N., Hakim, G., Agmon-Gerstein, Y., Jeshurun-Gutshtat, M., Klein, I., Kopelen, H. & Lernerc, S. P., Jan 1 2019, In : Bladder Cancer. 5, 1, p. 21-29 9 p.

Research output: Contribution to journalArticle

Hydrogel
Mitomycin
Carcinoma
Therapeutics
Compassionate Use Trials
Uterine Artery Embolization
Cone-Beam Computed Tomography
Aortography
Therapeutics
Uterine Artery

The role of perioperative nonsteroidal anti-inflammatory drugs use in cataract surgery

Brandsdorfer, A., Patel, S. H. & Chuck, R. S., Jan 1 2019, In : Current Opinion in Ophthalmology. 30, 1, p. 44-49 6 p.

Research output: Contribution to journalArticle

Cataract
Anti-Inflammatory Agents
Pharmaceutical Preparations
Macular Edema
Mydriasis

The Temporal Relationship between Pain Intensity and Pain Interference and Incident Dementia

Ezzati, A., Wang, C., Katz, M. J., Derby, C. A., Zammit, A. R., Zimmerman, M. E., Pavlovic, J. M., Sliwinski, M. J. & Lipton, R. B., Jan 1 2019, In : Current Alzheimer research. 16, 2, p. 109-115 7 p.

Research output: Contribution to journalArticle

Dementia
Pain
Chronic Pain
Independent Living
Proportional Hazards Models

The travels of mRNAs in neurons: do they know where they are going?

Das, S., Singer, R. H. & Yoon, Y. J., Aug 1 2019, In : Current Opinion in Neurobiology. 57, p. 110-116 7 p.

Research output: Contribution to journalReview article

Neurons
Messenger RNA
Dendrites
Axons
RNA
Chronic Obstructive Pulmonary Disease
Patient Care

Third Tofo Advanced Study Week on Emerging and Re-emerging Viruses, 2018

Badolo, A., Burt, F., Daniel, S., Fearns, R., Gudo, E. S., Kielian, M., Lescar, J., Shi, Y., von Brunn, A., Weiss, S. R. & Hilgenfeld, R., Feb 1 2019, In : Antiviral Research. 162, p. 142-150 9 p.

Research output: Contribution to journalReview article

Mozambique
Flavivirus
Viruses
Lassa virus
Crimean-Congo hemorrhagic fever virus

Thromboembolic events and need for anticoagulation therapy following left atrial appendage occlusion in patients with electrical isolation of the appendage

Gadiyaram, V. K., Mohanty, S., Gianni, C., Trivedi, C., Al-Ahmad, A., Burkhardt, D. J., Gallinghouse, J. G., Hranitzky, P. M., Horton, R. P., Sanchez, J. E., Della Rocca, D. G., Di Biase, L., Price, M. J., Couts, L., Gibson, D. & Natale, A., Jan 1 2019, (Accepted/In press) In : Journal of Cardiovascular Electrophysiology.

Research output: Contribution to journalArticle

Atrial Appendage
Anticoagulants
Therapeutics
Atrial Fibrillation
Stroke

TIAM-1/GEF can shape somatosensory dendrites independently of its GEF activity by regulating F-actin localization

Tang, L. T., Diaz-Balzac, C. A., Rahman, M., Ramirez-Suarez, N. J., Salzberg, Y., Lázaro-Peña, M. I. & Buelow, H. E., Jan 29 2019, In : eLife. 8

Research output: Contribution to journalArticle

Open Access
Dynamic mechanical analysis
Dendrites
Actins
Guanine Nucleotide Exchange Factors
Physical vapor deposition
Imaginal Discs
Neurogenesis
Drosophila
Drosophila Proteins
Nucleic Acid Regulatory Sequences