Find Research Outputs


A cross-sectional analysis of dietary protein intake and body composition among Chinese Americans

Popp, C. J., Beasley, J. M., Yi, S. S., Hu, L. & Wylie-Rosett, J., Jan 1 2019, In : Journal of Nutritional Science.

Research output: Contribution to journalArticle

Asian Americans
protein bodies
Dietary Proteins
Body Composition
protein intake

Active-Site Glu165 Activation in Triosephosphate Isomerase and Its Deprotonation Kinetics

Deng, H., Dyer, R. B. & Callender, R., May 16 2019, In : Journal of Physical Chemistry B. 123, 19, p. 4230-4241 12 p.

Research output: Contribution to journalArticle

Triose-Phosphate Isomerase
Catalytic Domain
1 Citation (Scopus)

Acute glufosinate-based herbicide treatment in rats leads to increased ocular interleukin-1β and c-Fos protein levels, as well as intraocular pressure

Çomaklı, S., Sevim, Ç., Kontadakis, G., Doğan, E., Taghizadehghalehjoughi, A., Özkaraca, M., Aschner, M., Nikolouzakis, T. K. & Tsatsakis, A., Jan 1 2019, In : Toxicology Reports. 6, p. 155-160 6 p.

Research output: Contribution to journalArticle

Proto-Oncogene Proteins c-fos
Intraocular Pressure

Acute Lateral Medullary Infarct due to Giant Cell Arteritis: A Case Study

Dardick, J. M., Esenwa, C. C., Zampolin, R. L., Ustun, B., Ayesha, B., Kirchoff-Torres, K. F. & Liberman, A. L., Oct 1 2019, In : Stroke. 50, 10, p. e290-e293

Research output: Contribution to journalArticle

Open Access
Lateral Medullary Syndrome
Brain Infarction
Giant Cell Arteritis

ADAP-GC 4.0: Application of Clustering-Assisted Multivariate Curve Resolution to Spectral Deconvolution of Gas Chromatography-Mass Spectrometry Metabolomics Data

Smirnov, A., Qiu, Y., Jia, W., Walker, D. I., Jones, D. P. & Du, X., Jun 24 2019, In : Analytical Chemistry. 91, 14, p. 9069-9077 9 p.

Research output: Contribution to journalArticle

Mass spectrometers
Gas chromatography
Mass spectrometry
1 Citation (Scopus)

Adding Value in Radiology Reporting

Goldberg-Stein, S. & Chernyak, V., Jan 1 2019, In : Journal of the American College of Radiology.

Research output: Contribution to journalArticle

Patient Care Team
Artificial Intelligence
Diagnostic Errors
2 Citations (Scopus)

Adherence of cell-free DNA noninvasive prenatal screens to ACMG recommendations

Skotko, B. G., Allyse, M. A., Bajaj, K., Best, R. G., Klugman, S. D., Leach, M., Meredith, S., Michie, M., Stoll, K. & Gregg, A. R., Jan 1 2019, In : Genetics in Medicine.

Research output: Contribution to journalArticle

Medical Genetics
Prenatal Diagnosis

Adipose-derived mesenchymal stem cells ameliorate acute liver injury in rat model of CLP induced-sepsis via sTNFR1

Liang, H., Ding, X., Yu, Y., Zhang, H., Wang, L., Kan, Q., Ma, S., Guan, F. & Sun, T., Jan 1 2019, In : Experimental Cell Research.

Research output: Contribution to journalArticle

Tumor Necrosis Factor Receptors
Mesenchymal Stromal Cells

A direct comparison of interphase FISH versus low-coverage single cell sequencing to detect aneuploidy reveals respective strengths and weaknesses

Andriani, G. A., Maggi, E., Piqué, D., Zimmerman, S. E., Lee, M., Quispe-Tintaya, W., Maslov, A., Campisi, J., Vijg, J., Mar, J. C. & Montagna, C., Dec 1 2019, In : Scientific Reports. 9, 1, 10508.

Research output: Contribution to journalArticle

Open Access
Fluorescence In Situ Hybridization
2 Citations (Scopus)

Admixture mapping identifies novel loci for obstructive sleep apnea in Hispanic/Latino Americans

Wang, H., Cade, B. E., Sofer, T., Sands, S. A., Chen, H., Browning, S. R., Stilp, A. M., Louie, T. L., Thornton, T. A., Johnson, W. C., Below, J. E., Conomos, M. P., Evans, D. S., Gharib, S. A., Guo, X., Wood, A. C., Mei, H., Yaffe, K., Loredo, J. S., Ramos, A. R. & 23 others, Barrett-Connor, E., Ancoli-Israel, S., Zee, P. C., Arens, R., Shah, N. A., Taylor, K. D., Tranah, G. J., Stone, K. L., Hanis, C. L., Wilson, J. G., Gottlieb, D. J., Patel, S. R., Rice, K., Post, W. S., Rotter, J. I., Sunyaev, S. R., Cai, J., Lin, X., Purcell, S. M., Laurie, C. C., Saxena, R., Redline, S. & Zhu, X., Feb 15 2019, In : Human molecular genetics. 28, 4, p. 675-687 13 p.

Research output: Contribution to journalArticle

Obstructive Sleep Apnea
Hispanic Americans

A dual-enzymatically cross-linked injectable gelatin hydrogel loaded with BMSC improves neurological function recovery of traumatic brain injury in rats

Yao, M., Gao, F., Xu, R., Zhang, J., Chen, Y. & Guan, F., Oct 2019, In : Biomaterials Science. 7, 10, p. 4088-4098 11 p.

Research output: Contribution to journalArticle

Stem cells
Glucose Oxidase

Advanced glycation end product carboxymethyl-lysine and risk of incident peripheral artery disease in older adults: The Cardiovascular Health Study

Garg, P. K., Biggs, M. L., Barzilay, J., Djousse, L., Hirsch, C., Ix, J. H., Kizer, J., Tracy, R. P., Newman, A. B., Siscovick, D. S. & Mukamal, K. J., Jan 1 2019, In : Diabetes and Vascular Disease Research.

Research output: Contribution to journalLetter

Open Access
Advanced Glycosylation End Products
Peripheral Arterial Disease
Proportional Hazards Models
Coronary Disease
Chronic Renal Insufficiency
Sodium Bicarbonate
Open Access
Peer Review
Oxidative stress
Chagas Disease
Trypanosoma cruzi
2 Citations (Scopus)
Quality of Life
Chronic Disease
Theoretical Models

Adverse Event Profiles of High Dose Botulinum Toxin Injections for Spasticity

Kirshblum, S., Solinsky, R., Jasey, N., Hampton, S., Didesch, M., Seidel, B. & Botticello, A., Jan 1 2019, (Accepted/In press) In : PM and R.

Research output: Contribution to journalArticle

Botulinum Toxins
Physical and Rehabilitation Medicine
Type A Botulinum Toxins
3 Citations (Scopus)

A farnesyltransferase inhibitor activates lysosomes and reduces tau pathology in mice with tauopathy

Hernandez, I., Luna, G., Rauch, J. N., Reis, S. A., Giroux, M., Karch, C. M., Boctor, D., Sibih, Y. E., Storm, N. J., Diaz, A., Kaushik, S., Zekanowski, C., Kang, A. A., Hinman, C. R., Cerovac, V., Guzman, E., Zhou, H., Haggarty, S. J., Goate, A. M., Fisher, S. K. & 2 others, Cuervo, A. M. & Kosik, K. S., Jan 1 2019, In : Science Translational Medicine. 11, 485

Research output: Contribution to journalArticle


African American Patients With Hidradenitis Suppurativa Have Significant Health Care Disparities: A Retrospective Study

Soliman, Y. S., Hoffman, L. K., Guzman, A. K., Patel, Z. S., Lowes, M. A. & Cohen, S. R., May 1 2019, In : Journal of cutaneous medicine and surgery. 23, 3, p. 334-336 3 p.

Research output: Contribution to journalArticle

Hidradenitis Suppurativa
Healthcare Disparities
Skin Pigmentation
African Americans
Retrospective Studies
36 Citations (Scopus)

A fully magnetically levitated left ventricular assist device - Final report

Mehra, M. R., Uriel, N., Naka, Y., Cleveland, J. C., Yuzefpolskaya, M., Salerno, C. T., Walsh, M. N., Milano, C. A., Patel, C. B., Hutchins, S. W., Ransom, J., Ewald, G. A., Itoh, A., Raval, N. Y., Silvestry, S. C., Cogswell, R., John, R., Bhimaraj, A., Bruckner, B. A., Lowes, B. D. & 20 others, Um, J. Y., Jeevanandam, V., Sayer, G., Mangi, A. A., Molina, E. J., Sheikh, F., Aaronson, K., Pagani, F. D., Cotts, W. G., Tatooles, A. J., Babu, A., Chomsky, D., Katz, J. N., Tessmann, P. B., Dean, D., Krishnamoorthy, A., Chuang, J., Topuria, I., Sood, P. & Goldstein, D. J., Apr 25 2019, In : New England Journal of Medicine. 380, 17, p. 1618-1627 10 p.

Research output: Contribution to journalArticle

Heart-Assist Devices
Equipment and Supplies
Heart Failure

Age- And stress-associated C. Elegans granulins impair lysosomal function and induce a compensatory HLH-30/TFEB transcriptional response

Butler, V. J., Gao, F., Corrales, C. I., Cortopassi, W. A., Caballero, B., Vohra, M., Ashrafi, K., Cuervo, A. M., Jacobson, M. P., Coppola, G. & Kao, A. W., Jan 1 2019, In : PLoS genetics. 15, 8, e1008295.

Research output: Contribution to journalArticle

Open Access
Caenorhabditis elegans
neurodegenerative diseases

Age at natural menopause and risk of incident cardiovascular disease: a pooled analysis of individual patient data

Zhu, D., Chung, H. F., Dobson, A. J., Pandeya, N., Giles, G. G., Bruinsma, F., Brunner, E. J., Kuh, D., Hardy, R., Avis, N. E., Gold, E. B., Derby, C. A., Matthews, K. A., Cade, J. E., Greenwood, D. C., Demakakos, P., Brown, D. E., Sievert, L. L., Anderson, D., Hayashi, K. & 7 others, Lee, J. S., Mizunuma, H., Tillin, T., Simonsen, M. K., Adami, H. O., Weiderpass, E. & Mishra, G. D., Nov 2019, In : The Lancet Public Health. 4, 11, p. e553-e564

Research output: Contribution to journalArticle

Open Access
Cardiovascular Diseases
Premature Menopause
Coronary Disease

Age-dependent decline of hypothalamic HIF2 in response to insulin and its contribution to advanced age-associated metabolic disorders in mice

Wang, Z., Khor, S. & Cai, D., Jan 1 2019, In : Journal of Biological Chemistry. 294, 13, p. 4946-4955 10 p.

Research output: Contribution to journalArticle

Weight Gain
endothelial PAS domain-containing protein 1

A genome-wide association study identifies blood disorder-related variants influencing hemoglobin A1c with implications for glycemic status in U.S. hispanics/latinos

Moon, J. Y., Louie, T. L., Jain, D., Sofer, T., Schurmann, C., Below, J. E., Lai, C. Q., Aviles-Santa, M. L., Talavera, G. A., Smith, C. E., Petty, L. E., Bottinger, E. P., Chen, Y. D. I., Taylor, K. D., Daviglus, M. L., Cai, J., Wang, T., Tucker, K. L., Ordovás, J. M., Hanis, C. L. & 5 others, Loos, R. J. F., Schneiderman, N., Rotter, J. I., Kaplan, R. C. & Qi, Q., Sep 1 2019, In : Diabetes care. 42, 9, p. 1784-1791 8 p.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Hispanic Americans

Aggregation properties of triamcinolone acetonide injection in human serum: Considerations when performing epidural steroid injections

Wahezi, S. E., Mohamed, S. E., Lederman, A. & Beck, A. P., Jan 1 2019, In : Journal of Pain Research. 12, p. 1033-1039 7 p.

Research output: Contribution to journalArticle

Open Access
Epidural Injections
Triamcinolone Acetonide

Agranulocytosis from Outpatient Antimicrobial Treatment with Ceftriaxone: A Case Report

Genchanok, Y., Tolu, S. S., Wang, H. & Arora, S., Jan 1 2019, In : The Permanente journal. 23

Research output: Contribution to journalArticle

Granulocyte Colony-Stimulating Factor
3 Citations (Scopus)
Open Access
Alzheimer Disease
Vascular Dementia

AGRP neurons modulate fasting-induced anxiolytic effects

Li, C., Hou, Y., Zhang, J., Sui, G., Du, X-L., Licinio, J., Wong, M. L. & Yang, Y., Dec 1 2019, In : Translational Psychiatry. 9, 1, 111.

Research output: Contribution to journalArticle

Open Access
Agouti-Related Protein
Anti-Anxiety Agents

A human cadaveric model for effective instruction of lateral canthotomy and cantholysis

Patel, S. R., Mishall, P. L. & Barmettler, A., Jan 1 2019, In : Orbit (London).

Research output: Contribution to journalArticle

Compartment Syndromes
Patient Care

A Hyperstabilizing Mutation in the Base of the Ebola Virus Glycoprotein Acts at Multiple Steps To Abrogate Viral Entry

Fels, J. M., Spence, J. S., Bortz, R. H., Bornholdt, Z. A. & Chandran, K., Jul 9 2019, In : mBio. 10, 4

Research output: Contribution to journalArticle

Open Access
Virus Internalization
Ebola Vaccines
1 Citation (Scopus)

Airway Inflammation and Lung Function in Sickle Cell Disease

De, A., Agrawal, S., Morrone, K., Zhang, J., Bjorklund, N. L., Manwani, D. & Rastogi, D., Sep 2019, In : Pediatric, Allergy, Immunology, and Pulmonology. 32, 3, p. 92-102 11 p.

Research output: Contribution to journalArticle

Sickle Cell Anemia
Leukotriene B4

A Key Differential Diagnosis for Physicians - Major Depression or Burnout?

Oquendo, M. A., Bernstein, C. A. & Mayer, L. E. S., Nov 2019, In : JAMA Psychiatry. 76, 11, 1 p.

Research output: Contribution to journalComment/debate

Differential Diagnosis

Akt3-Mediated Protection Against Inflammatory Demyelinating Disease

DuBois, J. C., Ray, A. K., Gruber, R. C., Zhang, Y., Aflakpui, R., Macian-Juan, F. & Shafit-Zagardo, B., Jan 1 2019, In : Frontiers in immunology. 10, 1 p.

Research output: Contribution to journalArticle

Open Access
Demyelinating Diseases
Autoimmune Experimental Encephalomyelitis
Myelin-Oligodendrocyte Glycoprotein

Albumin-binding PSMA ligands: Implications for expanding the therapeutic window

Kelly, J. M., Amor-Coarasa, A., Ponnala, S., Nikolopoulou, A., Williams, C., DiMagno, S. G. & Babich, J. W., May 1 2019, In : Journal of Nuclear Medicine. 60, 5, p. 656-663 8 p.

Research output: Contribution to journalArticle


Alcohol metabolism contributes to brain histone acetylation

Mews, P., Egervari, G., Nativio, R., Sidoli, S., Donahue, G., Lombroso, S. I., Alexander, D. C., Riesche, S. L., Heller, E. A., Nestler, E. J., Garcia, B. A. & Berger, S. L., Oct 31 2019, In : Nature. 574, 7780, p. 717-721 5 p.

Research output: Contribution to journalArticle

Acetyl Coenzyme A

Alcohol use, acculturation and socioeconomic status among Hispanic/Latino men and women: The Hispanic community health study/study of Latinos

Castañeda, S. F., Garcia, M. L., Lopez-Gurrola, M., Stoutenberg, M., Emory, K., Daviglus, M. L., Kaplan, R. C., Giachello, A. L., Molina, K. M., Perreira, K. M., Youngblood, M. E., Vidot, D. C. & Talavera, G. A., Apr 1 2019, In : PLoS ONE. 14, 4, e0214906.

Research output: Contribution to journalArticle

Open Access
community health
socioeconomic status
Hispanic Americans

A left ventricular end-diastolic dimension less than 6.0 cm is associated with mortality after implantation of an axial-flow pump

Kawabori, M., Kurihara, C., Conyer, R., Sugiura, T., Critsinelis, A. C., Lee, V. V., Civitello, A. B. & Morgan, J. A., Jun 2019, In : Journal of Thoracic and Cardiovascular Surgery. 157, 6, p. 2302-2310 9 p.

Research output: Contribution to journalArticle

Heart Failure
Equipment Design
1 Citation (Scopus)

Allograft inflammatory factor-1 supports macrophage survival and efferocytosis and limits necrosis in atherosclerotic plaques

Egaña-Gorroño, L., Chinnasamy, P., Casimiro, I., Almonte, V. M., Parikh, D., Oliveira-Paula, G. H., Jayakumar, S., Law, C., Riascos-Bernal, D. F. & Sibinga, N. E. S., Jan 1 2019, (Accepted/In press) In : Atherosclerosis.

Research output: Contribution to journalArticle

Open Access
Atherosclerotic Plaques
Apolipoproteins E
1 Citation (Scopus)

Allosteres to regulate neurotransmitter sulfonation

Darrah, K., Wang, T., Cook, I. T., Cacace, M., Deiters, A. & Leyh, T. S., Jan 1 2019, In : Journal of Biological Chemistry. 294, 7, p. 2293-2301 9 p.

Research output: Contribution to journalArticle

Neurotransmitter Agents
Free energy
Allosteric Site

Altered parasite life-cycle processes characterize Babesia divergens infection in human sickle cell anemia

Cursino-Santos, J. R., Singh, M., Senaldi, E., Manwani, D., Yazdanbakhsh, K. & Lobo, C. A., Jan 1 2019, In : Haematologica. 104, 11, p. 2189-2199 11 p.

Research output: Contribution to journalArticle

Open Access
Sickle Cell Anemia
Life Cycle Stages

Aluminium levels in hair and urine are associated with overweight and obesity in a non-occupationally exposed population

Tinkov, A. A., Skalnaya, M. G., Aaseth, J., Ajsuvakova, O. P., Aschner, M. & Skalny, A. V., Dec 1 2019, In : Journal of Trace Elements in Medicine and Biology. 56, p. 139-145 7 p.

Research output: Contribution to journalArticle


A major role of TWEAK/Fn14 axis as a therapeutic target for post-angioplasty restenosis

Méndez-Barbero, N., Gutierrez-Muñoz, C., Madrigal-Matute, J., Mínguez, P., Egido, J., Michel, J. B., Martín-Ventura, J. L., Esteban, V. & Blanco-Colio, L. M., Aug 2019, In : EBioMedicine. 46, p. 274-289 16 p.

Research output: Contribution to journalArticle

Open Access
Vascular Smooth Muscle
Smooth Muscle Myocytes

Amantadine Augmentation in Pediatric Catatonia: A Case Report and Review of the Literature

Hutchison, L., Silber, Y., Rollhaus, E. & Gnerre, C., Jan 1 2019, (Accepted/In press) In : Psychosomatics.

Research output: Contribution to journalArticle


A mass spectrometry-based assay using metabolic labeling to rapidly monitor chromatin accessibility of modified histone proteins

Sidoli, S., Lopes, M., Lund, P. J., Goldman, N., Fasolino, M., Coradin, M., Kulej, K., Bhanu, N. V., Vahedi, G. & Garcia, B. A., Dec 1 2019, In : Scientific Reports. 9, 1, 13613.

Research output: Contribution to journalArticle

Open Access
Post Translational Protein Processing
Mass Spectrometry

American College of Rheumatology Provisional Criteria for Clinically Relevant Improvement in Children and Adolescents With Childhood-Onset Systemic Lupus Erythematosus

the Paediatric Rheumatology International Trial Organisation and Pediatric Rheumatology Collaborative Study Group, May 1 2019, In : Arthritis Care and Research. 71, 5, p. 579-590 12 p.

Research output: Contribution to journalArticle

Systemic Lupus Erythematosus
Area Under Curve
Sensitivity and Specificity

A meta-analysis of genome-wide association studies identifies multiple longevity genes

Deelen, J., Evans, D. S., Arking, D. E., Tesi, N., Nygaard, M., Liu, X., Wojczynski, M. K., Biggs, M. L., van der Spek, A., Atzmon, G., Ware, E. B., Sarnowski, C., Smith, A. V., Seppälä, I., Cordell, H. J., Dose, J., Amin, N., Arnold, A. M., Ayers, K. L., Barzilai, N. & 64 others, Becker, E. J., Beekman, M., Blanché, H., Christensen, K., Christiansen, L., Collerton, J. C., Cubaynes, S., Cummings, S. R., Davies, K., Debrabant, B., Deleuze, J. F., Duncan, R., Faul, J. D., Franceschi, C., Galan, P., Gudnason, V., Harris, T. B., Huisman, M., Hurme, M. A., Jagger, C., Jansen, I., Jylhä, M., Kähönen, M., Karasik, D., Kardia, S. L. R., Kingston, A., Kirkwood, T. B. L., Launer, L. J., Lehtimäki, T., Lieb, W., Lyytikäinen, L. P., Martin-Ruiz, C., Min, J., Nebel, A., Newman, A. B., Nie, C., Nohr, E. A., Orwoll, E. S., Perls, T. T., Province, M. A., Psaty, B. M., Raitakari, O. T., Reinders, M. J. T., Robine, J. M., Rotter, J. I., Sebastiani, P., Smith, J., Sørensen, T. I. A., Taylor, K. D., Uitterlinden, A. G., van der Flier, W., van der Lee, S. J., van Duijn, C. M., van Heemst, D., Vaupel, J. W., Weir, D., Ye, K., Zeng, Y., Zheng, W., Holstege, H., Kiel, D. P., Lunetta, K. L., Slagboom, P. E. & Murabito, J. M., Dec 1 2019, In : Nature communications. 10, 1, 3669.

Research output: Contribution to journalArticle

Open Access
gene expression
Genome-Wide Association Study
Gene expression

A miRNA expression signature in breast tumor tissue is associated with risk of distant metastasis

Rohan, T. E., Wang, T., Weinmann, S., Wang, Y., Lin, J., Ginsberg, M. S. & Loudig, O., Apr 1 2019, In : Cancer Research. 79, 7, p. 1705-1713 9 p.

Research output: Contribution to journalArticle

Open Access
Breast Neoplasms
Neoplasm Metastasis
Logistic Models
Lymph Nodes
1 Citation (Scopus)

A mobile-phone based high-resolution microendoscope to image cervical precancer

Grant, B. D., Quang, T., Possati-Resende, J. C., Scapulatempo-Neto, C., de Macedo Matsushita, G., Mauad, E. C., Stoler, M. H., Castle, P. E., Guerreiro Fregnani, J. H. T., Schmeler, K. M. & Richards-Kortum, R., Feb 1 2019, In : PLoS One. 14, 2, e0211045.

Research output: Contribution to journalArticle

Cell Phones
Mobile phones
Acetic Acid
acetic acid

A Modified Laryngeal Stent for Glotto-Subglottic Stenosis: A Novel Stent for Better Outcomes

Wilcox, J. D. & Nassar, M., Jan 1 2019, (Accepted/In press) In : Ear, Nose and Throat Journal.

Research output: Contribution to journalArticle

Open Access
Pathologic Constriction

A modifier in the 129S2/SvPasCrl genome is responsible for the viability of Notch1[12f/12f] mice

Varshney, S., Wei, H. X., Batista, F., Nauman, M., Sundaram, S., Siminovitch, K., Tanwar, A. & Stanley, P., Oct 7 2019, In : BMC Developmental Biology. 19, 1, 19.

Research output: Contribution to journalArticle

Open Access
Embryonic Structures
Epidermal Growth Factor
2 Citations (Scopus)

A mouse model for the most common form of heart failure

Amgalan, D. & Kitsis, R. N., Apr 18 2019, In : Nature. 568, 7752, p. 324-325 2 p.

Research output: Contribution to journalArticle

Open Access
Heart Failure