Find Research Outputs

2018
1 Citations

A Cyfip2-Dependent Excitatory Interneuron Pathway Establishes the Innate Startle Threshold

Marsden, K. C., Jain, R. A., Wolman, M. A., Echeverry, F. A., Nelson, J. C., Hayer, K. E., Miltenberg, B., Pereda, A. E. & Granato, M., Apr 17 2018, In : Cell Reports. 23, 3, p. 878-887 10 p.

Research output: Contribution to journalArticle

Fragile X Mental Retardation Protein
Interneurons
Zebrafish
Startle Reflex
Genes

A data extraction algorithm for assessment of contraceptive counseling and provision

Roser, B. J., Rubin, S. E., Nagarajan, N., Wieland, D. L. & Benfield, N. C., Jan 1 2018, (Accepted/In press) In : American Journal of Obstetrics and Gynecology.

Research output: Contribution to journalArticle

Contraceptive Agents
Contraception
Counseling
Electronic Health Records
International Classification of Diseases

Addressing maternal mortality: the pregnant cardiac patient

Wolfe, D. S., Hameed, A. B., Taub, C. C., Zaidi, A. N. & Bortnick, A., Jan 1 2018, (Accepted/In press) In : American Journal of Obstetrics and Gynecology.

Research output: Contribution to journalArticle

Maternal Mortality
Pregnancy
Patient Education
Postpartum Period
Heart Diseases

Addressing social determinants of health in an ambulatory setting: quasi-experimental controlled study of a curricular intervention for residents

Hassan, I., Mansour, M., Narayan, L., Browder, C., Patel, V. V., LeFrancois, D. & Shapiro, L., Apr 13 2018, (Accepted/In press) In : Journal of General Internal Medicine. p. 1-3 3 p.

Research output: Contribution to journalArticle

Social Determinants of Health
Non-Randomized Controlled Trials

A deep learning approach to automate refinement of somatic variant calling from cancer sequencing data

Ainscough, B. J., Barnell, E. K., Ronning, P., Campbell, K. M., Wagner, A. H., Fehniger, T. A., Dunn, G. P., Uppaluri, R., Govindan, R., Rohan, T. E., Griffith, M., Mardis, E. R., Swamidass, S. J. & Griffith, O. L., Jan 1 2018, (Accepted/In press) In : Nature Genetics.

Research output: Contribution to journalArticle

Learning
Neoplasms
Machine Learning

Adherence patterns to extended cervical screening intervals in women undergoing human papillomavirus (HPV) and cytology cotesting

Rendle, K. A., Schiffman, M., Cheung, L. C., Kinney, W. K., Fetterman, B., Poitras, N. E., Lorey, T. & Castle, P. E., Apr 1 2018, In : Preventive Medicine. 109, p. 44-50 7 p.

Research output: Contribution to journalArticle

Cell Biology
Hispanic Americans
African Americans
Managed Care Programs
Early Detection of Cancer

A diagnostically challenging infusion reaction-Kounis, Takotsubo, or the ATAK!

Mustehsan, M. H., Jahufar, F. & Arora, S., Jan 1 2018, (Accepted/In press) In : JAMA Internal Medicine.

Research output: Contribution to journalArticle

Adiposity, history of diabetes, and risk of pancreatic cancer in postmenopausal women

Arthur, R., Kabat, G. C., Kim, M., Ho, G. Y. F., Chlebowski, R. T., Pan, K. & Rohan, T. E., Jan 1 2018, (Accepted/In press) In : Annals of Epidemiology.

Research output: Contribution to journalArticle

Adiposity
Pancreatic Neoplasms
Waist Circumference
Confidence Intervals
Body Mass Index

Adiposity at different periods of life and risk of adult glioma in a cohort of postmenopausal women

Kabat, G. C. & Rohan, T. E., Jun 1 2018, In : Cancer Epidemiology. 54, p. 71-74 4 p.

Research output: Contribution to journalArticle

Adiposity
Glioma
Body Mass Index
Waist-Hip Ratio
Waist Circumference
1 Citations

Adiposity in juvenile psoriatic arthritis

for the CARRA Legacy Registry Investigators, Mar 1 2018, In : Journal of Rheumatology. 45, 3, p. 411-418 8 p.

Research output: Contribution to journalArticle

Juvenile Arthritis
Adiposity
Registries
Rheumatology
Pediatrics

A direct tissue-grafting approach to increasing endogenous brown fat

Blumenfeld, N. R., Kang, H. J., Fenzl, A., Song, Z., Chung, J. J., Singh, R., Johnson, R., Karakecili, A., Feranil, J. B., Rossen, N. S., Zhang, V., Jaggi, S., McCarty, B., Bessler, S., Schwartz, G. J., Grant, R., Korner, J., Kiefer, F. W., Gillette, B. M. & Sia, S. K., Dec 1 2018, In : Scientific Reports. 8, 1, 7957.

Research output: Contribution to journalArticle

Tissue Transplantation
Brown Adipose Tissue
White Adipose Tissue
Pharmacology
Subcutaneous Fat

A distinct T follicular helper cell subset infiltrates the brain in murine neuropsychiatric lupus

Jain, S., Stock, A., Macian, F. & Putterman, C., Mar 13 2018, In : Frontiers in Immunology. 9, MAR, 487.

Research output: Contribution to journalArticle

Helper-Inducer T-Lymphocytes
T-Lymphocytes
Brain
Central Nervous System Lupus Vasculitis
Choroid Plexus

Adjudicated heart failure in HIV-infected and uninfected men and women

Feinstein, M. J., Steverson, A. B., Ning, H., Pawlowski, A. E., Schneider, D., Ahmad, F. S., Sanders, J. M., Sinha, A., Nance, R. M., Achenbach, C. J., Delaney, J. A. C., Heckbert, S. R., Shah, S. J., Hanna, D. B., Hsue, P. Y., Bloomfield, G. S., Longenecker, C. T., Crane, H. M. & Lloyd-Jones, D. M., Nov 1 2018, In : Journal of the American Heart Association. 7, 21, e009985.

Research output: Contribution to journalArticle

Heart Failure
HIV
CD4 Lymphocyte Count
Viral Load
Confidence Intervals

Adjustment for covariates using summary statistics of genome-wide association studies

Wang, T., Xue, X. N., Xie, X., Ye, Q. K., Zhu, X. & Elston, R. C., Jan 1 2018, (Accepted/In press) In : Genetic Epidemiology.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Linear Models
Epidemiology
35 Citations

Adjuvant chemotherapy guided by a 21-gene expression assay in breast cancer

Sparano, J. A., Gray, R. J., Makower, D. F., Pritchard, K. I., Albain, K. S., Hayes, D. F., Geyer, C. E., Dees, E. C., Goetz, M. P., Olson, J. A., Lively, T., Badve, S. S., Saphner, T. J., Wagner, L. I., Whelan, T. J., Ellis, M. J., Paik, S., Wood, W. C., Ravdin, P. M., Keane, M. M. & 10 othersGomez Moreno, H. L., Reddy, P. S., Goggins, T. F., Mayer, I. A., Brufsky, A. M., Toppmeyer, D. L., Kaklamani, V. G., Berenberg, J. L., Abrams, J. & Sledge, G. W., Jul 12 2018, In : New England Journal of Medicine. 379, 2, p. 111-121 11 p.

Research output: Contribution to journalArticle

Adjuvant Chemotherapy
Breast Neoplasms
Gene Expression
Recurrence
Drug Therapy
Carboplatin
Paclitaxel
Radiation
Carcinoma
Drug Therapy
1 Citations

Adolescent Perspectives on the Burden of a Parent's Migraine: Results from the CaMEO Study

Buse, D. C., Powers, S. W., Gelfand, A. A., VanderPluym, J. H., Fanning, K. M., Reed, M. L., Adams, A. M. & Lipton, R. B., Apr 1 2018, In : Headache. 58, 4, p. 512-524 13 p.

Research output: Contribution to journalArticle

Migraine Disorders
Parents
Headache
Anxiety
Depression

A double negative: Inhibition of hepatic gi signaling improves glucose homeostasis

Spiegel, A. M., Feb 1 2018, In : Journal of Clinical Investigation. 128, 2, p. 567-569 3 p.

Research output: Contribution to journalReview article

Homeostasis
Glucose
Liver
Glucagon
Hepatocytes
1 Citations

Adrenal serotonin derives from accumulation by the antidepressant-sensitive serotonin transporter

Brindley, R. L., Bauer, M. B., Walker, L. A., Quinlan, M. A., Carneiro, A. M. D., Sze, J. Y., Blakely, R. D. & Currie, K. P. M., Jan 1 2018, (Accepted/In press) In : Pharmacological Research.

Research output: Contribution to journalArticle

Serotonin Plasma Membrane Transport Proteins
Antidepressive Agents
Serotonin
Chromaffin Cells
Sympathetic Nervous System
2 Citations

Adrenergic nerve degeneration in bone marrow drives aging of the hematopoietic stem cell niche

Maryanovich, M., Zahalka, A. H., Pierce, H., Pinho, S., Nakahara, F., Asada, N., Wei, Q., Wang, X., Ciero, P., Xu, J., Leftin, A. & Frenette, P. S., May 7 2018, (Accepted/In press) In : Nature Medicine. p. 1-10 10 p.

Research output: Contribution to journalArticle

Stem Cell Niche
Nerve Degeneration
Hematopoietic Stem Cells
Stem cells
Adrenergic Agents

Adrenoleukodystrophy: Guidance for Adrenal Surveillance in Males Identified by Newborn Screen

Pediatric Endocrine Society Drug and Therapeutics/Rare Diseases Committee, Nov 1 2018, In : The Journal of clinical endocrinology and metabolism. 103, 11, p. 4324-4331 8 p.

Research output: Contribution to journalArticle

Adrenoleukodystrophy
Pediatrics
Adrenal Insufficiency
Newborn Infant
Screening
1 Citations

A Drosophila Model of Intellectual Disability Caused by Mutations in the Histone Demethylase KDM5

Zamurrad, S., Hatch, H. A. M., Drelon, C., Belalcazar, H. M. & Secombe, J., Feb 27 2018, In : Cell Reports. 22, 9, p. 2455-2468 14 p.

Research output: Contribution to journalArticle

Histone Demethylases
Diptera
Intellectual Disability
Drosophila
Genes
2 Citations

Advanced glycation end products alter steroidogenic gene expression by granulosa cells: An effect partially reversible by vitamin D

Merhi, Z., Buyuk, E. & Cipolla, M. J., Jun 1 2018, In : Molecular Human Reproduction. 24, 6, p. 318-326 9 p.

Research output: Contribution to journalArticle

Advanced Glycosylation End Products
Granulosa Cells
Vitamin D
Gene Expression
Follicular Fluid
2 Citations

Advances in Understanding the Molecular Basis of the Mediterranean Diet Effect

Corella, D., Coltell, O., Macian, F. & Ordovás, J. M., Mar 25 2018, In : Annual review of food science and technology. 9, p. 227-249 23 p.

Research output: Contribution to journalReview article

Mediterranean Diet
Mediterranean diet
Food
cardiovascular diseases
protective effect

Advantages of Molecular Weight Identification during Native MS Screening

Khan, A., Bresnick, A., Cahill, S., Girvin, M., Almo, S. & Quinn, R., May 9 2018, (Accepted/In press) In : Planta Medica.

Research output: Contribution to journalArticle

Screening
Molecular Weight
Molecular weight
Mass spectrometry
Ligands

Aerobic exercise training and inducible inflammation: Results of a randomized controlled trial in healthy, young adults

Sloan, R. P., Shapiro, P. A., McKinley, P. S., Bartels, M. N., Shimbo, D., Lauriola, V., Karmally, W., Pavlicova, M., Choi, C. J., Choo, T. H., Scodes, J. M., Flood, P. & Tracey, K. J., Sep 1 2018, In : Journal of the American Heart Association. 7, 17, e010201.

Research output: Contribution to journalArticle

Young Adult
Randomized Controlled Trials
Exercise
Inflammation
Interleukin-6
1 Citations

Affinity purification of neuropeptide precursors from mice lacking carboxypeptidase E activity

Fricker, L., Jan 1 2018, Methods in Molecular Biology. Humana Press Inc., p. 199-208 10 p. (Methods in Molecular Biology; vol. 1719).

Research output: Chapter in Book/Report/Conference proceedingChapter

Carboxypeptidase H
Neuropeptides
Peptides
Peptide Hormones
Neuroendocrine Cells

A Forward Genetic Screen in Zebrafish Identifies the G-Protein-Coupled Receptor CaSR as a Modulator of Sensorimotor Decision Making

Jain, R. A., Wolman, M. A., Marsden, K. C., Nelson, J. C., Shoenhard, H., Echeverry, F. A., Szi, C., Bell, H., Skinner, J., Cobbs, E. N., Sawada, K., Zamora, A. D., Pereda, A. E. & Granato, M., Jan 1 2018, (Accepted/In press) In : Current Biology.

Research output: Contribution to journalArticle

Startle Reflex
Choice Behavior
Calcium-Sensing Receptors
Zebrafish
G-Protein-Coupled Receptors
1 Citations

A framework for selection of blood-based biomarkers for geroscience-guided clinical trials: report from the TAME Biomarkers Workgroup

Justice, J. N., Ferrucci, L., Newman, A. B., Aroda, V. R., Bahnson, J. L., Divers, J., Espeland, M. A., Marcovina, S., Pollak, M. N., Kritchevsky, S. B., Barzilai, N. & Kuchel, G. A., Jan 1 2018, (Accepted/In press) In : GeroScience.

Research output: Contribution to journalArticle

Metformin
Biomarkers
Clinical Trials
Patient Selection
Interleukin-6 Receptors
1 Citations

Age- and tissue-specific expression of senescence biomarkers in mice

Hudgins, A. D., Tazearslan, C., Tare, A., Zhu, Y., Huffman, D. & Suh, Y., Feb 23 2018, In : Frontiers in Genetics. 9, FEB, 59.

Research output: Contribution to journalArticle

Biomarkers
Phenotype
Cell Aging
Genotype
Medicine

A Genome-Wide Association Study Identifies a Candidate Gene Associated With Atazanavir Exposure Measured in Hair

Tamraz, B., Huang, Y., French, A. L., Kassaye, S., Anastos, K., Nowicki, M. J., Gange, S., Gustafson, D. R., Bacchetti, P., Greenblatt, R. M., Hysi, P. G. & Aouizerat, B. E., Jan 1 2018, (Accepted/In press) In : Clinical Pharmacology and Therapeutics.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Hair
Genes
HIV
Pharmacogenetics
4 Citations

A genome-wide association study in hispanics/latinos identifies novel signals for lung function the hispanic community health study/study of latinos

Burkart, K. M., Sofer, T., London, S. J., Manichaikul, A., Hartwig, F. P., Yan, Q., Artigas, M. S., Avila, L., Chen, W., Thomas, S. D., Diaz, A. A., Hall, I. P., Horta, B. L., Kaplan, R. C., Laurie, C. C., Menezes, A. M., Morrison, J. V., Oelsner, E. C., Rastogi, D., Rich, S. S. & 6 othersSoto-Quiros, M., Stilp, A. M., Tobin, M. D., Wain, L. V., Celedón, J. C. & Graham Barr, R., Jul 15 2018, In : American Journal of Respiratory and Critical Care Medicine. 198, 2, p. 208-219 12 p.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Hispanic Americans
Lung
Chronic Obstructive Pulmonary Disease
Health

A genome-wide association study of idiopathic dilated cardiomyopathy in African Americans

Xu, H., Dorn, G. W., Shetty, A., Parihar, A., Dave, T., Robinson, S. W., Gottlieb, S. S., Donahue, M. P., Tomaselli, G. F., Kraus, W. E., Mitchell, B. D. & Liggett, S. B., Mar 1 2018, In : Journal of Personalized Medicine. 8, 1, 11.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Dilated Cardiomyopathy
African Americans
Genes
Calcium Signaling

Aging, cardiac repair and Smad3

Chen, B., Huang, S. & Frangogiannis, N. G., Sep 1 2018, In : Aging. 10, 9, p. 2230-2232 3 p.

Research output: Contribution to journalComment/debate

Aging as a Biological Target for Prevention and Therapy

Barzilai, N., Cuervo, A. M. & Austad, S., Oct 2 2018, In : JAMA - Journal of the American Medical Association. 320, 13, p. 1321-1322 2 p.

Research output: Contribution to journalReview article

Nutrigenomics
Biological Phenomena
Genetic Engineering
Health
Therapeutics

Aging health and R & D for healthy longevity must be included into the WHO work program

Stambler, I., Jin, K., Lederman, S., Barzilai, N., Jay Olshansky, S., Omokaro, E., Barratt, J., Anisimov, V. N., Rattan, S., Yang, S., Forster, M. & Byles, J., Apr 1 2018, In : Aging and Disease. 9, 2, p. 331-333 3 p.

Research output: Contribution to journalEditorial

Health

Agreement between Crohn's Disease Endoscopic Severity Scores Derived from Live, Video-recorded, and Central Readings

Côté-Daigneault, J., Peerani, F., Katsanos, K., Ullman, T., Marion, J., Legnani, P., Cohen, B. & Colombel, J. F., Apr 23 2018, In : Inflammatory Bowel Diseases. 24, 5, p. e6-e7

Research output: Contribution to journalLetter

Crohn Disease
Reading
3 Citations
Fibroblast Growth Factors
Bile Acids and Salts
Hypothalamus
Glucose
Taurocholic Acid

A healthy lifestyle index and its association with risk of breast, endometrial, and ovarian cancer among Canadian women

Arthur, R., Kirsh, V. A., Kreiger, N. & Rohan, T., Apr 17 2018, (Accepted/In press) In : Cancer Causes and Control. p. 1-9 9 p.

Research output: Contribution to journalArticle

Endometrial Neoplasms
Ovarian Neoplasms
Breast Neoplasms
Confidence Intervals
Risk Reduction Behavior
2 Citations
Human Herpesvirus 2
Human Herpesvirus 1
Glycoproteins
Vaccines
Skin
2 Citations

A high parasite density environment induces transcriptional changes and cell death in Plasmodium falciparum blood stages

Chou, E. S., Abidi, S. Z., Teye, M., Leliwa-Sytek, A., Rask, T. S., Cobbold, S. A., Tonkin-Hill, G. Q., Subramaniam, K. S., Sexton, A. E., Creek, D. J., Daily, J. P., Duffy, M. F. & Day, K. P., Mar 1 2018, In : FEBS Journal. 285, 5, p. 848-870 23 p.

Research output: Contribution to journalArticle

Cell death
Plasmodium falciparum
Schizonts
Parasites
Blood
1 Citations

A Hospital Based Retrospective Study of Acute Postpartum Headache

Vgontzas, A. & Robbins, M. S., Jan 1 2018, (Accepted/In press) In : Headache.

Research output: Contribution to journalArticle

Postpartum Period
Headache
Retrospective Studies
Post-Dural Puncture Headache
Pre-Eclampsia

A humanized mouse model of liver fibrosis following expansion of transplanted hepatic stellate cells

Benten, D., Kluwe, J., Wirth, J. W., Thiele, N. D., Follenzi, A., Bhargava, K. K., Palestro, C. J., Koepke, M., Tjandra, R., Volz, T., Lutgehetmann, M. & Gupta, S., Apr 1 2018, In : Laboratory Investigation. 98, 4, p. 525-536 12 p.

Research output: Contribution to journalArticle

Hepatic Stellate Cells
Liver Cirrhosis
Liver
Bile Ducts
Ligation

Airway inflammation in sickle cell disease—A translational perspective

De, A., Manwani, D. & Rastogi, D., Apr 1 2018, In : Pediatric Pulmonology. 53, 4, p. 400-411 12 p.

Research output: Contribution to journalReview article

Sickle Cell Anemia
Asthma
Inflammation
Lung
Respiratory Hypersensitivity

A kind of mirraculas paradise by Sandra Allen

Forman, H. L., Jun 1 2018, In : Psychiatric Times. 35, 6, p. 16E-16F

Research output: Contribution to journalShort survey

1 Citations

All in the family: Proneural bHLH genes and neuronal diversity

Baker, N. E. & Brown, N. L., May 1 2018, In : Development (Cambridge). 145, 9, dev159426.

Research output: Contribution to journalReview article

Genes
Drosophila
Gene Duplication
Porifera
Primates

Allosteric regulators selectively prevent Ca2+-feedback of CaV and NaV channels

Niu, J., Dick, I. E., Yang, W., Bamgboye, M. A., Yue, D. T., Tomaselli, G. F., Inoue, T. & Ben-Johny, M., Sep 10 2018, In : eLife. 7

Research output: Contribution to journalArticle

Calmodulin
Feedback
Allosteric Site
Proteins
src Homology Domains

Alternate fractionation for hepatic tumors

Méndez Romero, A., Brunner, T. B., Kirichenko, A. V., Tome, W. A., Liang, Y., Ogden, N. & Heijmen, B. J. M., Jan 1 2018, Medical Radiology. Springer Verlag, p. 173-201 29 p. (Medical Radiology).

Research output: Chapter in Book/Report/Conference proceedingChapter

Radiation
Liver
Floxuridine
Neoplasms
Liver Diseases
phosphine
Resuscitation
Cardiopulmonary Resuscitation
Heart Arrest
Poisoning