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  Activated ERK2 is a monomer in vitro with or without divalent cations and when complexed to the cytoplasmic scaffold PEA-15

  Kaoud, T. S., Devkota, A. K., Harris, R., Rana, M. S., Abramczyk, O., Warthaka, M., Lee, S., Girvin, M. E., Riggs, A. F. & Dalby, K. N., May 31 2011, In: Biochemistry. 50, 21, p. 4568-4578 11 p.

  Research output: Contribution to journal › Article › peer-review
  32 Scopus citations

• Activated kRas protects colon cancer cells from cucurbitacin-induced apoptosis: The role of p53 and p21

  Escandell, J. M., Kaler, P., Recio, M. C., Sasazuki, T., Shirasawa, S., Augenlicht, L., Ríos, J. L. & Klampfer, L., Jul 15 2008, In: Biochemical Pharmacology. 76, 2, p. 198-207 10 p.

  Research output: Contribution to journal › Article › peer-review
  44 Scopus citations

• Activated neutrophils are associated with pediatric cerebral malaria vasculopathy in Malawian children

  Feintuch, C. M., Saidi, A., Seydel, K., Chen, G., Goldman-Yassen, A., Mita-Mendoza, N. K., Kim, R. S., Frenette, P. S., Taylor, T. & Daily, J. P., Feb 16 2016, In: mBio. 7, 1, e01300-15.

  Research output: Contribution to journal › Article › peer-review
  44 Scopus citations

• Activated NKT cells inhibit autoimmune diabetes through tolerogenic recruitment of dendritic cells to pancreatic lymph nodes

  Chen, Y. G., Choisy-Rossi, C. M., Holl, T. M., Chapman, H. D., Besra, G. S., Porcelli, S. A., Shaffer, D. J., Roopenian, D., Wilson, S. B. & Serreze, D. V., Feb 1 2005, In: Journal of Immunology. 174, 3, p. 1196-1204 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  118 Scopus citations

• Activated pregnenolone X-receptor is a target for ketoconazole and its analogs

  Wang, H., Huang, H., Li, H., Teotico, D. G., Sinz, M., Baker, S. D., Staudinger, J., Kalpana, G., Redinbo, M. R. & Mani, S., Apr 15 2007, In: Clinical Cancer Research. 13, 8, p. 2488-2495 8 p.

  Research output: Contribution to journal › Article › peer-review
  86 Scopus citations

• Activated STING in a vascular and pulmonary syndrome

  Liu, Y., Jesus, A. A., Marrero, B., Yang, D., Ramsey, S. E., Montealegre Sanchez, G. A., Tenbrock, K., Wittkowski, H., Jones, O. Y., Kuehn, H. S., Lee, C. C. R., DiMattia, M. A., Cowen, E. W., Gonzalez, B., Palmer, I., DiGiovanna, J. J., Biancotto, A., Kim, H., Tsai, W. L., Trier, A. M. & 32 others, Huang, Y., Stone, D. L., Hill, S., Kim, H. J., St Hilaire, C., Gurprasad, S., Plass, N., Chapelle, D., Horkayne-Szakaly, I., Foell, D., Barysenka, A., Candotti, F., Holland, S. M., Hughes, J. D., Mehmet, H., Issekutz, A. C., Raffeld, M., McElwee, J., Fontana, J. R., Minniti, C. P., Moir, S., Kastner, D. L., Gadina, M., Steven, A. C., Wingfield, P. T., Brooks, S. R., Rosenzweig, S. D., Fleisher, T. A., Deng, Z., Boehm, M., Paller, A. S. & Goldbach-Mansky, R., Aug 7 2014, In: New England Journal of Medicine. 371, 6, p. 507-518 12 p.

  Research output: Contribution to journal › Article › peer-review
  717 Scopus citations

• Activated suppressor T cells in leprosy

  Mehra, V., Convit, J., Rubinstein, A. & Bloom, B. R., 1982, In: Journal of Immunology. 129, 5, p. 1946-1951 6 p.

  Research output: Contribution to journal › Article › peer-review
  55 Scopus citations

• Activating and inactivating mutations of the α subunit of G_i2 protein have opposite effects on proliferation of NIH 3T3 cells

  Hermouet, S., Merendino, J. J., Silvio Gutkind, J. & Spiegel, A. M., 1991, In: Proceedings of the National Academy of Sciences of the United States of America. 88, 23, p. 10455-10459 5 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  104 Scopus citations

• Activating FLT3 mutations in CD117/KIT⁺ T-cell acute lymphoblastic leukemias

  Paietta, E., Ferrando, A. A., Neuberg, D., Bennett, J. M., Racevskis, J., Lazarus, H., Dewald, G., Rowe, J. M., Wiernik, P. H., Tallman, M. S. & Look, A. T., Jul 15 2004, In: Blood. 104, 2, p. 558-560 3 p.

  Research output: Contribution to journal › Article › peer-review
  82 Scopus citations

• Activating mutations in the NT5C2 nucleotidase gene drive chemotherapy resistance in relapsed ALL

  Tzoneva, G., Perez-Garcia, A., Carpenter, Z., Khiabanian, H., Tosello, V., Allegretta, M., Paietta, E., Racevskis, J., Rowe, J. M., Tallman, M. S., Paganin, M., Basso, G., Hof, J., Kirschner-Schwabe, R., Palomero, T., Rabadan, R. & Ferrando, A., Mar 2013, In: Nature Medicine. 19, 3, p. 368-371 4 p.

  Research output: Contribution to journal › Article › peer-review
  242 Scopus citations

• Activating Mutations in β-Catenin in Colon Cancer Cells Alter Their Interaction with Macrophages; the Role of Snail

  Kaler, P., Augenlicht, L. & Klampfer, L., Sep 21 2012, In: PloS one. 7, 9, e45462.

  Research output: Contribution to journal › Article › peer-review
  32 Scopus citations

• Activating mutations of the Noonan syndrome-associated SHP2/PTPN11 gene in human solid tumors and adult acute myelogenous leukemia

  Bentires-Alj, M., Paez, J. G., David, F. S., Keilhack, H., Halmos, B., Naoki, K., Maris, J. M., Richardson, A., Bardelli, A., Sagarbaker, D. J., Richards, W. G., Du, J., Girard, L., Minna, J. D., Loh, M. L., Fisher, D. E., Velculescu, V. E., Vogelstein, B., Meyerson, M., Sellers, W. R. & 1 others, Neel, B. G., Dec 15 2004, In: Cancer research. 64, 24, p. 8816-8820 5 p.

  Research output: Contribution to journal › Article › peer-review
  401 Scopus citations

• Activating mutations of the stimulatory g protein in the mcCune–albright syndrome

  Weinstein, L. S., Shenker, A., Friedman, E., Spiegel, A. M., Gejman, P. V. & Merino, M. J., Dec 12 1991, In: New England Journal of Medicine. 325, 24, p. 1688-1695 8 p.

  Research output: Contribution to journal › Article › peer-review
  1355 Scopus citations

• Activating photoactivatable proteins with laser light to visualize membrane systems and membrane traffic in living cells

  Snapp, E. L. & Lajoie, P., Nov 2011, In: Cold Spring Harbor Protocols. 6, 11, p. 1368-1369 2 p.

  Research output: Contribution to journal › Article › peer-review
  4 Scopus citations

• Activating the phosphate nucleophile at the catalytic site of purine nucleoside phosphorylase: A vibrational spectroscopic study

  Deng, H., Lewandowicz, A., Schramm, V. L. & Callender, R., Aug 11 2004, In: Journal of the American Chemical Society. 126, 31, p. 9516-9517 2 p.

  Research output: Contribution to journal › Article › peer-review
  37 Scopus citations

• Activation and membrane binding of carboxypeptidase E

  Fricker, L. D., Dec 1988, In: Journal of Cellular Biochemistry. 38, 4, p. 279-289 11 p.

  Research output: Contribution to journal › Article › peer-review
  30 Scopus citations

• Activation and repression of a β-globin gene in cell hybrids is accompanied by a shift in its temporal replication

  Dhar, V., Skoultchi, A. I. & Schildkraut, C. L., 1989, In: Molecular and cellular biology. 9, 8, p. 3524-3532 9 p.

  Research output: Contribution to journal › Article › peer-review
  60 Scopus citations

• Activation-Induced Autophagy Is Preserved in CD4⁺ T-Cells in Familial Longevity

  Raz, Y., Guerrero-Ros, I., Maier, A., Slagboom, P. E., Atzmon, G., Barzilai, N. & Macian, F., Sep 1 2017, In: Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 72, 9, p. 1201-1206 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  25 Scopus citations

• Activation-induced cytidine deaminase deaminates deoxycytidine on single-stranded DNA but requires the action of RNase

  Bransteitter, R., Pham, P., Scharfft, M. D. & Goodman, M. F., Apr 1 2003, In: Proceedings of the National Academy of Sciences of the United States of America. 100, 7, p. 4102-4107 6 p.

  Research output: Contribution to journal › Article › peer-review
  561 Scopus citations

• Activation-induced cytidine deaminase turns on somatic hypermutation in hybridomas

  Martin, A., Bardwell, P. D., Woo, C. J., Fan, M., Shulman, M. J. & Scharff, M. D., Feb 14 2002, In: Nature. 415, 6873, p. 802-806 5 p.

  Research output: Contribution to journal › Article › peer-review
  224 Scopus citations

• Activation mapping in patients with coronary artery disease with multiple ventricular tachycardia configurations: Occurrence and therapeutic implications of widely separate apparent sites of origin

  Waspe, L. E., Brodman, R., Kim, S. G., Matos, J. A., Johnston, D. R., Scavin, G. M. & Fisher, J. D., 1985, In: Journal of the American College of Cardiology. 5, 5, p. 1075-1086 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  34 Scopus citations

• Activation of 2',5'-oligoadenylate synthetase activity on induction of HL-60 leukemia cell differentiation

  Schwartz, E. L. & Nilson, L. A., 1989, In: Molecular and cellular biology. 9, 9, p. 3897-3903 7 p.

  Research output: Contribution to journal › Article › peer-review
  13 Scopus citations

• Activation of Akt/protein kinase B overcomes a G₂/M cell cycle checkpoint induced by DNA damage

  Kandel, E. S., Skeen, J., Majewski, N., Di Cristofano, A., Pandolfi, P. P., Feliciano, C. S., Gartel, A. & Hay, N., Nov 1 2002, In: Molecular and cellular biology. 22, 22, p. 7831-7841 11 p.

  Research output: Contribution to journal › Article › peer-review
  253 Scopus citations

• Activation of Akt as a mechanism for tumor immune evasion

  Noh, K. H., Kang, T. H., Kim, J. H., Pai, S. I., Lin, K. Y., Hung, C. F., Wu, T. C. & Kim, T. W., 2009, In: Molecular Therapy. 17, 3, p. 439-447 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  70 Scopus citations

• Activation of AMP-activated protein kinase by metformin improves left ventricular function and survival in heart failure

  Gundewar, S., Calvert, J. W., Jha, S., Toedt-Pingel, I., Ji, S. Y., Nunez, D., Ramachandran, A., Anaya-Cisneros, M., Tian, R. & Lefer, D. J., Feb 13 2009, In: Circulation research. 104, 3, p. 403-411 9 p.

  Research output: Contribution to journal › Article › peer-review
  307 Scopus citations

• Activation of a selective pathway of lysosomal proteolysis in rat liver by prolonged starvation

  Cuervo, A. M., Knecht, E., Terlecky, S. R. & Dice, J. F., 1995, In: American Journal of Physiology - Cell Physiology. 269, 5 38-5, p. C1200-C1208

  Research output: Contribution to journal › Article › peer-review
  262 Scopus citations

• Activation of autophagic flux and the Nrf2/ARE signaling pathway by hydrogen sulfide protects against acrylonitrile-induced neurotoxicity in primary rat astrocytes

  Yang, B., Bai, Y., Yin, C., Qian, H., Xing, G., Wang, S., Li, F., Bian, J., Aschner, M. & Lu, R., Jun 1 2018, In: Archives of Toxicology. 92, 6, p. 2093-2108 16 p.

  Research output: Contribution to journal › Article › peer-review
  38 Scopus citations

• Activation of autophagy rescues synaptic and cognitive deficits in fragile X mice

  Yan, J., Porch, M. W., Court-Vazquez, B., Bennett, M. V. L. & Zukin, R. S., Oct 9 2018, In: Proceedings of the National Academy of Sciences of the United States of America. 115, 41, p. E9707-E9716

  Research output: Contribution to journal › Article › peer-review

  Open Access
  67 Scopus citations

• Activation of a voltage-insensitive conductance by inward calcium current

  Clusin, W., Spray, D. C. & Bennett, M. V. L., 1975, In: Nature. 256, 5516, p. 425-427 3 p.

  Research output: Contribution to journal › Article › peer-review
  39 Scopus citations

• Activation of blood clotting in patients with systemic lupus erythematosus. Relationship to disease activity

  Hardin, J. A., Cronlund, M., Haber, E. & Bloch, K. J., Sep 1978, In: The American Journal of Medicine. 65, 3, p. 430-436 7 p.

  Research output: Contribution to journal › Article › peer-review
  40 Scopus citations

• Activation of both the calpain and ubiquitin-proteasome systems contributes to septic cardiomyopathy through dystrophin loss/disruption and mTOR inhibition

  Freitas, A. C. S., Figueiredo, M. J., Campos, E. C., Soave, D. F., Ramos, S. G., Tanowitz, H. B. & Celes, M. R. N., Nov 2016, In: PloS one. 11, 11, e0166839.

  Research output: Contribution to journal › Article › peer-review
  12 Scopus citations

• Activation of Ca²⁺ current in Jurkat T cells following the depletion of Ca²⁺ stores by microsomal Ca²⁺-ATPase inhibitors

  Premack, B. A., McDonald, T. V. & Gardner, P., 1994, In: Journal of Immunology. 152, 11, p. 5226-5240 15 p.

  Research output: Contribution to journal › Article › peer-review
  130 Scopus citations

• Activation of CD8 T cells predicts progression of HIV infection in women coinfected with hepatitis C virus

  Kovacs, A., Karim, R., Mack, W. J., Xu, J., Chen, Z., Operskalski, E., Frederick, T., Landay, A., Voris, J., Spencer, L. S., Young, M. A., Tien, P. C., Augenbraun, M., Strickler, H. D. & Al-Harthi, L., 2010, In: Journal of Infectious Diseases. 201, 6, p. 823-834 12 p.

  Research output: Contribution to journal › Article › peer-review
  61 Scopus citations

• Activation of chaperone-mediated autophagy during oxidative stress

  Kiffin, R., Christian, C., Knecht, E. & Cuervo, A. M., Nov 2004, In: Molecular biology of the cell. 15, 11, p. 4829-4840 12 p.

  Research output: Contribution to journal › Article › peer-review
  455 Scopus citations

• Activation of cyclic AMP-dependent protein kinase isoenzymes: Studies using specific antisera

  Erlichman, J., Bloomgarden, D., Sarkar, D. & Rubin, C. S., Nov 1983, In: Archives of Biochemistry and Biophysics. 227, 1, p. 136-146 11 p.

  Research output: Contribution to journal › Article › peer-review
  9 Scopus citations

• Activation of cyclin D1 by estradiol and spermine in MCF-7 breast cancer cells: A mechanism involving the p38 MAP kinase and phosphorylation of ATF-2

  Lewis, J. S., Vijayanathan, V., Thomas, T. J., Pestell, R. G., Albanese, C., Gallo, M. A. & Thomas, T., 2005, In: Oncology Research. 15, 3, p. 113-128 16 p.

  Research output: Contribution to journal › Article › peer-review
  44 Scopus citations

• Activation of dopamine receptors in the nucleus accumbens promotes sucrose-reinforced cued approach behavior

  du Hoffmann, J. & Nicola, S. M., Jul 14 2016, In: Frontiers in Behavioral Neuroscience. 10, JULY, 144.

  Research output: Contribution to journal › Article › peer-review
  11 Scopus citations

• Activation of endogenous Cdc42 visualized in living cells

  Nalbant, P., Hodgson, L., Kraynov, V., Toutchkine, A. & Hahn, K. M., Sep 10 2004, In: Science. 305, 5690, p. 1615-1619 5 p.

  Research output: Contribution to journal › Article › peer-review
  300 Scopus citations

• Activation of Endothelial Cells in Conduit Veins of Dogs With Heart Failure and Veins of Normal Dogs After Vascular Stretch by Acute Volume Loading

  Colombo, P. C., Rastogi, S., Onat, D., Zacà, V., Gupta, R. C., Jorde, U. P. & Sabbah, H. N., Jun 2009, In: Journal of Cardiac Failure. 15, 5, p. 457-463 7 p.

  Research output: Contribution to journal › Article › peer-review
  24 Scopus citations

• Activation of ER stress and inhibition of EGFR N-glycosylation by tunicamycin enhances susceptibility of human non-small cell lung cancer cells to erlotinib

  Ling, Y. H., Li, T., Perez-Soler, R. & Haigentz, M., Jul 2009, In: Cancer Chemotherapy and Pharmacology. 64, 3, p. 539-548 10 p.

  Research output: Contribution to journal › Article › peer-review
  45 Scopus citations

• Activation of Estrogen Receptor G Protein–Coupled Receptor 30 Enhances Cholesterol Cholelithogenesis in Female Mice

  Wang, H. H., de Bari, O., Arnatt, C. K., Liu, M., Portincasa, P. & Wang, D. Q. H., Dec 2020, In: Hepatology. 72, 6, p. 2077-2089 13 p.

  Research output: Contribution to journal › Article › peer-review
  4 Scopus citations

• Activation of guanylate cyclase-C attenuates stretch responses and sensitization of mouse colorectal afferents

  Feng, B., Kiyatkin, M. E., La, J. H., Ge, P., Solinga, R., Silos-Santiago, I. & Gebhart, G. F., 2013, In: Journal of Neuroscience. 33, 23, p. 9831-9839 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  36 Scopus citations

• Activation of guinea pig macrophages by bacterial lipopolysaccharide requires bone marrow derived lymphocytes

  Wilton, J. M., Rosenstreich, D. L. & Oppenheim, J. J., 1975, In: Journal of Immunology. 114, 1, p. II

  Research output: Contribution to journal › Article › peer-review
  25 Scopus citations

• Activation of human macrophages. Comparison of other cytokines with interferon-γ

  Nathan, C. F., Prendergast, T. J., Wiebe, M. E., Stanley, E. R., Platzer, E., Remold, H. G., Welte, K., Rubin, B. Y. & Murray, H. W., 1984, In: Journal of Experimental Medicine. 160, 2, p. 600-605 6 p.

  Research output: Contribution to journal › Article › peer-review
  287 Scopus citations

• Activation of human plasminogen by urokinase. Partial characterization of a pre activation peptide

  Walther, P. J., Steinman, H. M., Hill, R. L. & McKee, P. A., 1974, In: Journal of Biological Chemistry. 249, 4, p. 1173-1181 9 p.

  Research output: Contribution to journal › Article › peer-review
  66 Scopus citations

• Activation of human β-globin genes from nonerythroid cells by fusion with murine erythroleukemia cells

  Pyati, J., Kucherlapati, R. S. & Skoultchi, A. I., 1980, In: Proceedings of the National Academy of Sciences of the United States of America. 77, 6 I, p. 3435-3439 5 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  14 Scopus citations

• Activation of hypothalamic astrocytes suppresses feeding without altering emotional states

  Sweeney, P., Qi, Y., Xu, Z. & Yang, Y., Dec 1 2016, In: Glia. 64, 12, p. 2263-2273 11 p.

  Research output: Contribution to journal › Article › peer-review
  29 Scopus citations

• Activation of hypothalamic S6 kinase mediates diet-induced hepatic insulin resistance in rats

  Ono, H., Pocai, A., Wang, Y., Sakoda, H., Asano, T., Backer, J. M., Schwartz, G. J. & Rossetti, L., Aug 1 2008, In: Journal of Clinical Investigation. 118, 8, p. 2959-2968 10 p.

  Research output: Contribution to journal › Article › peer-review
  140 Scopus citations

• Activation of invariant natural killer T cells redirects the inflammatory response in neonatal sepsis

  Bolognese, A. C., Yang, W. L., Hansen, L. W., Sharma, A., Nicastro, J. M., Coppa, G. F. & Wang, P., Apr 23 2018, In: Frontiers in immunology. 9, APR, 833.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  11 Scopus citations

• Activation of K_ATP channels suppresses glucose production in humans

  Kishore, P., Boucai, L., Zhang, K., Li, W., Koppaka, S., Kehlenbrink, S., Schiwek, A., Esterson, Y. B., Mehta, D., Bursheh, S., Su, Y., Gutierrez-Juarez, R., Muzumdar, R., Schwartz, G. J. & Hawkins, M., Dec 1 2011, In: Journal of Clinical Investigation. 121, 12, p. 4916-4920 5 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  82 Scopus citations