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• Tyr⁶⁸² in the intracellular domain of APP regulates amyloidogenic APP processing in vivo

  Barbagallo, A. P. M., Weldon, R., Tamayev, R., Zhou, D., Giliberto, L., Foreman, O. & D'Adamio, L., 2010, In: PloS one. 5, 11, e15503.

  Research output: Contribution to journal › Article › peer-review
  51 Scopus citations

• Tyrosine B10 and heme-ligand interactions of Lucina pectinata hemoglobin II: Control of heme reactivity

  Pietri, R., Granell, L., Cruz, A., De Jesús, W., Lewis, A., Leon, R., Cadilla, C. L. & Garriga, J. L., Mar 14 2005, In: Biochimica et Biophysica Acta - Proteins and Proteomics. 1747, 2, p. 195-203 9 p.

  Research output: Contribution to journal › Article › peer-review
  22 Scopus citations

• Tyrosine hydroxylase and regulation of dopamine synthesis

  Daubner, S. C., Le, T. & Wang, S., Apr 1 2011, In: Archives of Biochemistry and Biophysics. 508, 1, p. 1-12 12 p.

  Research output: Contribution to journal › Review article › peer-review
  481 Scopus citations

• Tyrosine hydroxylase regulation in adult rat striatum following short-term neonatal exposure to manganese

  Peres, T. V., Ong, L. K., Costa, A. P., Eyng, H., Venske, D. K. R., Colle, D., Gonçalves, F. M., Lopes, M. W., Farina, M., Aschner, M., Dickson, P. W., Dunkley, P. R. & Leal, R. B., Jun 2016, In: Metallomics. 8, 6, p. 597-604 8 p.

  Research output: Contribution to journal › Article › peer-review
  10 Scopus citations

• Tyrosine kinase activation in breast carcinoma with correlation to HER-2/neu gene amplification and receptor overexpression

  Bhargava, R., Naeem, R., Marconi, S., Luszcz, J., Garb, J., Gasparini, R. & Otis, C. N., Dec 1 2001, In: Human Pathology. 32, 12, p. 1344-1350 7 p.

  Research output: Contribution to journal › Article › peer-review
  11 Scopus citations

• Tyrosine Kinase and Mammalian Target of Rapamycin Inhibitors in the Treatment of Advanced Renal Cell Carcinoma: Practical Clinical Implications of Pharmacologic Features

  Parikh, R. A., Appleman, L. J., Beumer, J. H., Matczak, E. & Chu, E., Feb 1 2017, In: Clinical Genitourinary Cancer. 15, 1, p. 7-22 16 p.

  Research output: Contribution to journal › Review article › peer-review
  1 Scopus citations

• Tyrosine kinase inhibitors: a clinical perspective.

  Goel, S., Mani, S. & Perez-Soler, R., Jan 2002, In: Current oncology reports. 4, 1, p. 9-19 11 p.

  Research output: Contribution to journal › Review article › peer-review
  37 Scopus citations

• Tyrosine-phosphorylated epidermal growth factor receptor and cellular p130 provide high affinity binding substrates to analyze Crk-phosphotyrosine- dependent interactions in vitro

  Birge, R. B., Fajardo, J. E., Mayer, B. J. & Hanafusa, H., 1992, In: Journal of Biological Chemistry. 267, 15, p. 10588-10595 8 p.

  Research output: Contribution to journal › Article › peer-review
  98 Scopus citations

• Tyrosine phosphorylation of a common 57-kDa protein in growth factor-stimulated and -transformed cells

  Li, W., Yeung, Y. G. & Stanley, E. R., 1991, In: Journal of Biological Chemistry. 266, 11, p. 6808-6814 7 p.

  Research output: Contribution to journal › Article › peer-review
  34 Scopus citations

• Tyrosine phosphorylation of Munc18c regulates platelet-derived growth factor-stimulated glucose transporter 4 translocation in 3T3L1 adipocytes

  Umahara, M., Okada, S., Yamada, E., Saito, T., Ohshima, K., Hashimoto, K., Yamada, M., Shimizu, H., Pessin, J. E. & Mori, M., Jan 2008, In: Endocrinology. 149, 1, p. 40-49 10 p.

  Research output: Contribution to journal › Article › peer-review
  21 Scopus citations

• Tyrosine phosphorylation of the insulin receptor during insulin-stimulated internalization in rat hepatoma cells

  Backer, J. M., Kahn, C. R. & White, M. F., 1989, In: Journal of Biological Chemistry. 264, 3, p. 1694-1701 8 p.

  Research output: Contribution to journal › Article › peer-review
  54 Scopus citations

• Tyrosine phosphorylation of the insulin receptor is not required for receptor internalization: Studies in 2,4-dinitrophenol-treated cells

  Backer, J. M., Kahn, C. R. & White, M. F., 1989, In: Proceedings of the National Academy of Sciences of the United States of America. 86, 9, p. 3209-3213 5 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  37 Scopus citations

• Tyrosine phosphorylation of the β-amyloid precursor protein cytoplasmic tail promotes interaction with Shc

  Tarr, P. E., Roncarati, R., Pelicci, G., Pelicci, P. G. & D'Adamio, L., May 10 2002, In: Journal of Biological Chemistry. 277, 19, p. 16798-16804 7 p.

  Research output: Contribution to journal › Article › peer-review
  111 Scopus citations

• Tyrosine phosphorylation of Wiskott-Aldrich Syndrome Protein (WASP) by Hck regulates macrophage function

  Park, H., Dovas, A., Hanna, S., Lastrucci, C., Cougoule, C., Guiet, R., Maridonneau-Parini, I. & Cox, D., Mar 14 2014, In: Journal of Biological Chemistry. 289, 11, p. 7897-7906 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  17 Scopus citations

• Tyr phosphatase-mediated P-ERK inhibition suppresses senescence in EIA + v-raf transformed cells, which, paradoxically, are apoptosis-protected in a MEK-dependent manner

  de Vitis, S., Treglia, A. S., Ulianich, L., Turco, S., Terrazzano, G., Lombardi, A., Miele, C., Garbi, C., Beguinot, F. & di Jeso, B., Feb 2011, In: Neoplasia. 13, 2, p. 120-130 11 p.

  Research output: Contribution to journal › Article › peer-review
  15 Scopus citations

• TβR-I(6A) is a candidate tumor susceptibility allele

  Pasche, B., Kolachana, P., Nafa, K., Satagopan, J., Chen, Y. G., Lo, R. S., Brener, D., Yang, D., Kirstein, L., Oddoux, C., Ostrer, H., Vineis, P., Varesco, L., Jhanwar, S., Luzzatto, L., Massagué, J. & Offit, K., Nov 15 1999, In: Cancer research. 59, 22, p. 5678-5682 5 p.

  Research output: Contribution to journal › Article › peer-review
  134 Scopus citations

• U.S. Courts rule anti-prostitution policy restriction on AIDS funding violates right to free speech.

  Silver, E., Dec 1 2006, In: HIV/AIDS policy & law review / Canadian HIV/AIDS Legal Network. 11, 2-3, p. 54-55 2 p.

  Research output: Contribution to journal › Article › peer-review

• U.S. Centers for Disease Control and Prevention launches new chronic kidney disease surveillance system website

  Johns, T. & Jaar, B. G., 2013, In: BMC Nephrology. 14, 1, 196.

  Research output: Contribution to journal › Review article › peer-review
  4 Scopus citations

• U.S. Department of Health and Human Services National Institutes of Health Recombinant DNA Advisory Committee: Minutes of meeting: December 6, 2001

  Aguilar-Cordova, C. E., Macklin, R., Markert, M. L., Mickelson, C. A., Ando, D. G., Breakefield, X. O., Friedmann, T. C., Gordon, J. W., Greenblatt, J. J., Juengst, E. T., King, N. M. P. & Levi-Pearl, S. L., 2002, In: Human Gene Therapy. 13, 13, p. 1663-1673 11 p.

  Research output: Contribution to journal › Article › peer-review
  3 Scopus citations

• U.S. trends in antiretroviral therapy use, HIV RNA plasma viral loads, and CD4 T-lymphocyte cell counts among HIV-infected persons, 2000 to 2008

  Althoff, K. N., Buchacz, K., Irene Hall, H., Zhang, J., Hanna, D. B., Rebeiro, P., Gange, S. J., Moore, R. D., Kitahata, M. M., Gebo, K. A., Martin, J., Justice, A. C., Horberg, M. A., Hogg, R. S., Sterling, T. R., Cescon, A., Klein, M. B., Thorne, J. E., Crane, H. M., Mugavero, M. J., & 4 othersNapravnik, S., Kirk, G. D., Jacobson, L. P. & Brooks, J. T., Oct 16 2012, In: Annals of internal medicine. 157, 5, p. 325-335 11 p.

  Research output: Contribution to journal › Article › peer-review
  90 Scopus citations

• U.S. trends in inpatient utilization of fractional flow reserve and percutaneous coronary intervention

  Pothineni, N. V., Shah, N. S., Rochlani, Y., Nairooz, R., Raina, S., Leesar, M. A., Uretsky, B. F. & Hakeem, A., Feb 16 2016, In: Journal of the American College of Cardiology. 67, 6, p. 732-733 2 p.

  Research output: Contribution to journal › Letter › peer-review

  Open Access
  45 Scopus citations

• U2AF1 mutations induce oncogenic IRAK4 isoforms and activate innate immune pathways in myeloid malignancies

  Smith, M. A., Choudhary, G. S., Pellagatti, A., Choi, K., Bolanos, L. C., Bhagat, T. D., Gordon-Mitchell, S., Von Ahrens, D., Pradhan, K., Steeples, V., Kim, S., Steidl, U., Walter, M., Fraser, I. D. C., Kulkarni, A., Salomonis, N., Komurov, K., Boultwood, J., Verma, A. & Starczynowski, D. T., May 1 2019, In: Nature Cell Biology. 21, 5, p. 640-650 11 p.

  Research output: Contribution to journal › Article › peer-review
  75 Scopus citations

• Ubiquilin functions in autophagy and is degraded by chaperone-mediated autophagy

  Rothenberg, C., Srinivasan, D., Mah, L., Kaushik, S., Peterhoff, C. M., Ugolino, J., Fang, S., Cuervo, A. M., Nixon, R. A. & Monteiro, M. J., Jun 7 2010, In: Human molecular genetics. 19, 16, p. 3219-3232 14 p., ddq231.

  Research output: Contribution to journal › Article › peer-review
  179 Scopus citations

• Ubiquinol (reduced coenzyme Q10) as a metabolic resuscitator in post-cardiac arrest: A randomized, double-blind, placebo-controlled trial

  Holmberg, M. J., Andersen, L. W., Moskowitz, A., Berg, K. M., Cocchi, M. N., Chase, M., Liu, X., Kuhn, D. M., Grossestreuer, A. V., Hoeyer-Nielsen, A. K., Kirkegaard, H. & Donnino, M. W., May 2021, In: Resuscitation. 162, p. 388-395 8 p.

  Research output: Contribution to journal › Article › peer-review
  3 Scopus citations

• Ubiquitin and phosphorylated neurofilament epitopes in ballooned neurons of the extraocular muscle nuclei in a case of Werdnig-Hoffmann disease

  Kato, S. & Hirano, A., Jul 1 1990, In: Acta neuropathologica. 80, 3, p. 334-337 4 p.

  Research output: Contribution to journal › Article › peer-review
  29 Scopus citations

• Ubiquitinated eosinophilic granules in the inferior olivary nucleus

  KATO, S., HIRANO, A., SUENAGA, T. & YEN, S. H., Apr 1990, In: Neuropathology and Applied Neurobiology. 16, 2, p. 135-139 5 p.

  Research output: Contribution to journal › Article › peer-review
  8 Scopus citations

• Ubiquitination and degradation of the anti-apoptotic protein ARC by MDM2

  Foo, R. S. Y., Chan, L. K. W., Kitsis, R. N. & Bennett, M. R., Feb 23 2007, In: Journal of Biological Chemistry. 282, 8, p. 5529-5535 7 p.

  Research output: Contribution to journal › Article › peer-review
  68 Scopus citations

• Ubiquitination and proteasomal degradation of interferon regulatory factor-3 induced by Npro from a cytopathic bovine viral diarrhea virus

  Chen, Z., Rijnbrand, R., Jangra, R. K., Devaraj, S. G., Qu, L., Ma, Y., Lemon, S. M. & Li, K., Sep 30 2007, In: Virology. 366, 2, p. 277-292 16 p.

  Research output: Contribution to journal › Article › peer-review
  97 Scopus citations

• Ubiquitin Chains Are Remodeled at the Proteasome by Opposing Ubiquitin Ligase and Deubiquitinating Activities

  Crosas, B., Hanna, J., Kirkpatrick, D. S., Zhang, D. P., Tone, Y., Hathaway, NA. A., Buecker, C., Leggett, D. S., Schmidt, M., King, R. W., Gygi, SP. P. & Finley, D., Dec 29 2006, In: Cell. 127, 7, p. 1401-1413 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  240 Scopus citations

• Ubiquitin depletion and dominant-negative VPS4 inhibit rhabdovirus budding without affecting alphavirus budding

  Taylor, G. M., Hanson, P. I. & Kielian, M., Dec 2007, In: Journal of virology. 81, 24, p. 13631-13639 9 p.

  Research output: Contribution to journal › Article › peer-review
  67 Scopus citations

• Ubiquitin-immunoreactive filamentous inclusions in anterior horn cells of Guamanian and non-Guamanian amyotrophic lateral sclerosis

  Matsumoto, S., Hirano, A. & Goto, S., Jul 1 1990, In: Acta Neuropathologica. 80, 3, p. 233-238 6 p.

  Research output: Contribution to journal › Article › peer-review
  48 Scopus citations

• Ubiquitin immunoreactivity in kuru plaques in Creutzfeldt‐Jakob disease

  Suenaga, T., Hirano, A., Llena, J. F., Ksiezak‐Reding, H., Yen, SH. H. & Dickson, D. W., Aug 1990, In: Annals of Neurology. 28, 2, p. 174-177 4 p.

  Research output: Contribution to journal › Article › peer-review
  19 Scopus citations

• Ubiquitin-positive inclusion in anterior horn cells in subgroups of motor neuron diseases: A comparative study of adult-onset amyotrophic lateral sclerosis, juvenile amyotrophic lateral sclerosis and werdnig-hoffmann disease

  Matsumoto, S., Goto, S., Kusaka, H., Imai, T., Murakami, N., Hashizume, Y., Okazaki, H. & Hirano, A., Apr 1993, In: Journal of the Neurological Sciences. 115, 2, p. 208-213 6 p.

  Research output: Contribution to journal › Article › peer-review
  40 Scopus citations

• Ubiquitylated PCNA plays a role in somatic hypermutation and class-switch recombination and is required for meiotic progression

  Roa, S., Avdievich, E., Peled, J. U., MacCarthy, T., Werling, U., Fei, L. K., Kan, R., Zhao, C., Bergman, A., Cohen, P. E., Edelmann, W. & Scharff, M. D., Oct 21 2008, In: Proceedings of the National Academy of Sciences of the United States of America. 105, 42, p. 16248-16253 6 p.

  Research output: Contribution to journal › Article › peer-review
  81 Scopus citations

• Ubrogepant, an Acute Treatment for Migraine, Improved Patient-Reported Functional Disability and Satisfaction in 2 Single-Attack Phase 3 Randomized Trials, ACHIEVE I and II

  Dodick, D. W., Lipton, R. B., Ailani, J., Halker Singh, R. B., Shewale, A. R., Zhao, S., Trugman, J. M., Yu, S. Y. & Viswanathan, H. N., Apr 1 2020, In: Headache. 60, 4, p. 686-700 15 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  29 Scopus citations

• Ubrogepant for the treatment of migraine

  Dodick, D. W., Lipton, R. B., Ailani, J., Lu, K., Finnegan, M., Trugman, J. M. & Szegedi, A., Dec 5 2019, In: New England Journal of Medicine. 381, 23, p. 2230-2241 12 p.

  Research output: Contribution to journal › Article › peer-review
  143 Scopus citations

• UCN-01 alters phosphorylation of Akt and GSK3β and induces apoptosis in six independent human neuroblastoma cell lines

  Shankar, S. L., Krupski, M., Parashar, B., Okwuaka, C., O'Guin, K., Mani, S. & Shafit-Zagardo, B., Aug 2004, In: Journal of Neurochemistry. 90, 3, p. 702-711 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  15 Scopus citations

• UCP1-independent signaling involving SERCA2bmediated calcium cycling regulates beige fat thermogenesis and systemic glucose homeostasis

  Ikeda, K., Kang, Q., Yoneshiro, T., Camporez, J. P., Maki, H., Homma, M., Shinoda, K., Chen, Y., Lu, X., Maretich, P., Tajima, K., Ajuwon, K. M., Soga, T. & Kajimura, S., 2017, In: Nature Medicine. 23, 12, p. 1454-1465 12 p.

  Research output: Contribution to journal › Article › peer-review
  280 Scopus citations

• UCP2 regulates energy metabolism and differentiation potential of human pluripotent stem cells

  Zhang, J., Khvorostov, I., Hong, J. S., Oktay, Y., Vergnes, L., Nuebel, E., Wahjudi, P. N., Setoguchi, K., Wang, G., Do, A., Jung, H. J., McCaffery, J. M., Kurland, I. J., Reue, K., Lee, W. N. P., Koehler, C. M. & Teitell, M. A., Dec 14 2011, In: EMBO Journal. 30, 24, p. 4860-4873 14 p.

  Research output: Contribution to journal › Article › peer-review
  372 Scopus citations

• UDP-(5F)-GlcNAc acts as a slow-binding inhibitor of MshA, a retaining glycosyltransferase

  Frantom, P. A., Coward, J. K. & Blanchard, J. S., May 19 2010, In: Journal of the American Chemical Society. 132, 19, p. 6626-6627 2 p.

  Research output: Contribution to journal › Article › peer-review
  31 Scopus citations

• UDPglucuronosyltransferase deficiency in man and animals

  Chowdhury, J. R., Chowdhury, N. R. & Arias, I. M., Jan 1 1984, In: Biochemical Society transactions. 12, 1, p. 81-83 3 p.

  Research output: Contribution to journal › Article › peer-review
  11 Scopus citations

• UDSNB 3.0 Neuropsychological Test Norms in Older Adults from a Diverse Community: Results from the Einstein Aging Study (EAS)

  Wang, C., Katz, M. J., Chang, K. H., Qin, J., Lipton, R. B., Zwerling, J. L., Sliwinski, M. J., Derby, C. A., Rabin, L. A. & Abner, E., 2021, In: Journal of Alzheimer's Disease. 83, 4, p. 1665-1678 14 p.

  Research output: Contribution to journal › Article › peer-review

• UFT plus leucovorin in advanced hepatobiliary tumors and pancreatic adenocarcinomas

  Mani, S., Nov 13 1997, In: ONCOLOGY. 11, 9 SUPPL. 10, p. 124-127 4 p.

  Research output: Contribution to journal › Article › peer-review
  5 Scopus citations

• UGT1A1 polymorphism predicts irinotecan toxicity: Evolving proof

  Mani, S., 2001, In: AAPS PharmSci. 3, 3

  Research output: Contribution to journal › Article › peer-review
  6 Scopus citations

• UGT1A1 polymorphism predicts irinotecan toxicity: Evolving proof

  Mani, S., Dec 1 2001, In: AAPS Journal. 3, 3, p. XIII

  Research output: Contribution to journal › Article › peer-review

• UKALLXII/ECOG2993: Addition of imatinib to a standard treatment regimen enhances long-term outcomes in Philadelphia positive acute lymphoblastic leukemia

  Fielding, A. K., Rowe, J. M., Buck, G., Foroni, L., Gerrard, G., Litzow, M. R., Lazarus, H., Luger, S. M., Marks, D. I., McMillan, A. K., Moorman, A. V., Patel, B., Paietta, E., Tallman, M. S. & Goldstone, A. H., Feb 6 2014, In: Blood. 123, 6, p. 843-850 8 p.

  Research output: Contribution to journal › Article › peer-review
  238 Scopus citations

• UL36p is required for efficient transport of membrane-associated herpes simplex virus type 1 along microtubules

  Shanda, S. K. & Wilson, D. W., Aug 2008, In: Journal of virology. 82, 15, p. 7388-7394 7 p.

  Research output: Contribution to journal › Article › peer-review
  63 Scopus citations

• UL5, A protein required for HSV DNA synthesis: Genetic analysis, overexpression in Escherichia coli, and generation of polyclonal antibodies

  Zhu, L. & Weller, S. K., Oct 1988, In: Virology. 166, 2, p. 366-378 13 p.

  Research output: Contribution to journal › Article › peer-review
  30 Scopus citations

• Ulcerative Colitis Complicated by Amyloidosis

  RAND, JAMES. A., BRANDT, LAWRENCE. J., BECKER, NORWIN. H. & LYNCH, JOHN., Aug 1980, In: The American Journal of Gastroenterology. 74, 2, p. 185-188 4 p.

  Research output: Contribution to journal › Article › peer-review
  14 Scopus citations

• Ulnar Collateral Ligament Reconstruction of the Elbow: The Docking Technique

  Camp, C. L., Dines, J. S., Voleti, P. B., James, E. W. & Altchek, D. W., Jun 1 2016, In: Arthroscopy Techniques. 5, 3, p. e519-e523

  Research output: Contribution to journal › Article › peer-review

  Open Access
  21 Scopus citations