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• Targeting Mac-1-mediated leukocyte–RBC interactions uncouples the benefits for acute vaso-occlusion and chronic organ damage

  Chen, G., Chang, J., Zhang, D., Pinho, S., Jang, J. E. & Frenette, P. S., Oct 1 2016, In: Experimental Hematology. 44, 10, p. 940-946 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  11 Scopus citations

• Targeting mesothelioma using an infectivity enhanced survivin-conditionally replicative adenoviruses

  Zhu, Z. B., Makhija, S. K., Lu, B., Wang, M., Wang, S., Takayama, K., Siegal, G. P., Reynolds, P. N. & Curiel, D. T., Sep 2006, In: Journal of Thoracic Oncology. 1, 7, p. 701-711 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  22 Scopus citations

• Targeting metabotropic glutamate receptors for the treatment of neuroinflammation

  Fazio, F., Ulivieri, M., Volpi, C., Gargaro, M. & Fallarino, F., Feb 2018, In: Current Opinion in Pharmacology. 38, p. 16-23 8 p.

  Research output: Contribution to journal › Review article › peer-review
  24 Scopus citations

• Targeting metabotropic glutamate receptors in neuroimmune communication

  Volpi, C., Fazio, F. & Fallarino, F., Sep 2012, In: Neuropharmacology. 63, 4, p. 501-506 6 p.

  Research output: Contribution to journal › Review article › peer-review
  18 Scopus citations

• Targeting mGlu receptors for optimization of antipsychotic activity and disease-modifying effect in schizophrenia

  Nicoletti, F., Orlando, R., Menna, L. D., Cannella, M., Notartomaso, S., Mascio, G., Iacovelli, L., Matrisciano, F., Fazio, F., Caraci, F., Copani, A., Battaglia, G. & Bruno, V., 2019, In: Frontiers in Psychiatry. 10, FEB, 49.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  23 Scopus citations

• Targeting microtubules for wound repair

  Charafeddine, R. A., Nosanchuk, J. D. & Sharp, D. J., Oct 1 2016, In: Advances in Wound Care. 5, 10, p. 444-454 11 p.

  Research output: Contribution to journal › Review article › peer-review
  8 Scopus citations

• Targeting mitochondrial calcium transport in myocardial infarction

  Frangogiannis, N. G., Jul 1 2018, In: Hellenic Journal of Cardiology. 59, 4, p. 223-225 3 p.

  Research output: Contribution to journal › Editorial › peer-review
  1 Scopus citations

• Targeting mitochondrial structure sensitizes acute myeloid Leukemia to venetoclax treatment

  Chen, X., Glytsou, C., Zhou, H., Narang, S., Reyna, D. E., Lopez, A., Sakellaropoulos, T., Gong, Y., Kloetgen, A., Yap, Y. S., Wang, E., Gavathiotis, E., Tsirigos, A., Tibes, R. & Aifantis, I., Jul 2019, In: Cancer discovery. 9, 7, p. 890-909 20 p.

  Research output: Contribution to journal › Article › peer-review
  92 Scopus citations

• Targeting mitochondria to oppose the progression of nonalcoholic fatty liver disease

  Grattagliano, I., Montezinho, L. P., Oliveira, P. J., Frühbeck, G., Gómez-Ambrosi, J., Montecucco, F., Carbone, F., Wieckowski, M. R., Wang, D. Q. H. & Portincasa, P., Feb 2019, In: Biochemical Pharmacology. 160, p. 34-45 12 p.

  Research output: Contribution to journal › Review article › peer-review
  31 Scopus citations

• Targeting Mycobacterium tuberculosis tumor necrosis factor alpha-downregulating genes for the development of antituberculous vaccines

  Olsen, A., Chen, Y., Ji, Q., Zhu, G., De Silva, A. D., Vilchèze, C., Weisbrod, T., Li, W., Xu, J., Larsen, M., Zhang, J., Porcelli, S. A., Jacobs, W. R. & Chan, J., 2016, In: mBio. 7, 3, e01023-15.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  25 Scopus citations

• Targeting non-pulmonary vein triggers in persistent atrial fibrillation: Results from a prospective, multicentre, observational registry

  Della Rocca, D. G., Di Biase, L., Mohanty, S., Trivedi, C., Gianni, C., Romero, J., Tarantino, N., Magnocavallo, M., Bassiouny, M., Natale, V. N., Mayedo, A. Q., Macdonald, B., Lavalle, C., Murtaza, G., Akella, K., Forleo, G. B., Al-Ahmad, A., Burkhardt, J. D., Gallinghouse, G. J., Sanchez, J. E., & 4 othersHorton, R. P., Viles-Gonzalez, J. F., Lakkireddy, D. & Natale, A., Dec 1 2021, In: Europace. 23, 12, p. 1939-1949 11 p.

  Research output: Contribution to journal › Article › peer-review
  5 Scopus citations

• Targeting of a conditionally replicative adenovirus agent to human squamous cell carcinomas of the head and neck

  Zhu, Z. B., Mathis, J. M., Makhija, S. K., Lu, B., Wang, M., Ji, S., Rivera, A. A., Rosenthal, E. L., Siegal, G. P. & Curiel, D. T., Nov 2007, In: International journal of oncology. 31, 5, p. 1213-1222 10 p.

  Research output: Contribution to journal › Article › peer-review
  13 Scopus citations

• Targeting of cre to the Foxg1 (BF-1) locus mediates loxP recombination in the telencephalon and other developing head structures

  Hébert, J. M. & McConnell, S. K., Jun 15 2000, In: Developmental Biology. 222, 2, p. 296-306 11 p.

  Research output: Contribution to journal › Article › peer-review
  427 Scopus citations

• Targeting of rough endoplasmic reticulum membrane proteins and ribosomes in invertebrate neurons

  Rolls, M. M., Hall, D. H., Victor, M., Stelzer, E. H. K. & Rapoport, T. A., 2002, In: Molecular biology of the cell. 13, 5, p. 1778-1791 14 p.

  Research output: Contribution to journal › Article › peer-review
  127 Scopus citations

• Targeting of the FYVE domain to endosomal membranes is regulated by a histidine switch

  Lee, S. A., Eyeson, R., Cheever, M. L., Geng, J., Verkhusha, V. V., Burd, C., Overduin, M. & Kutateladze, T. G., Sep 13 2005, In: Proceedings of the National Academy of Sciences of the United States of America. 102, 37, p. 13052-13057 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  83 Scopus citations

• Targeting of the GTPase Irgm1 to the phagosomal membrane via PtdIns(3,4)P₂ and PtdIns(3,4,5)P₃ promotes immunity to mycobacteria

  Tiwari, S., Choi, H. P., Matsuzawa, T., Pypaert, M. & MacMicking, J. D., 2009, In: Nature Immunology. 10, 8, p. 907-917 11 p.

  Research output: Contribution to journal › Article › peer-review
  95 Scopus citations

• Targeting PBK/TOPK decreases growth and survival of glioma initiating cells in vitro and attenuates tumor growth in vivo

  Joel, M., Mughal, A. A., Grieg, Z., Murrell, W., Palmero, S., Mikkelsen, B., Fjerdingstad, H. B., Sandberg, C. J., Behnan, J., Glover, J. C., Langmoen, I. A. & Stangeland, B., Jun 17 2015, In: Molecular Cancer. 14, 1, 121.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  63 Scopus citations

• Targeting pediatric pedestrian injury prevention efforts: Teasing the information through spatial analysis

  Statter, M., Schuble, T., Harris-Rosado, M., Liu, D. & Quinlan, K., Nov 1 2011, In: Journal of Trauma - Injury, Infection and Critical Care. 71, 5 SUPPL. 2, p. S511-S516

  Research output: Contribution to journal › Article › peer-review
  19 Scopus citations

• Targeting physical activity interventions for adults: When should intervention occur?

  Holliday, K. M., Lin, D. Y., Chakladar, S., Castañeda, S. F., Daviglus, M. L., Evenson, K. R., Marquez, D. X., Qi, Q., Shay, C. M., Sotres-Alvarez, D., Vidot, D. C., Zeng, D. & Avery, C. L., Apr 1 2017, In: Preventive Medicine. 97, p. 13-18 6 p.

  Research output: Contribution to journal › Article › peer-review
  3 Scopus citations

• Targeting plasmodium falciparum purine salvage enzymes: A look at structure-based drug development

  Donaldson, T. & Kim, K., Jan 1 2010, In: Infectious Disorders - Drug Targets. 10, 3, p. 191-199 9 p.

  Research output: Contribution to journal › Article › peer-review
  13 Scopus citations

• Targeting protein conformations with small molecules to control protein complexes

  Zacharioudakis, E. & Gavathiotis, E., 2022, (Accepted/In press) In: Trends in Biochemical Sciences.

  Research output: Contribution to journal › Review article › peer-review

• Targeting protein translation in human non-small cell lung cancer via combined MEK and mammalian target of rapamycin suppression

  Legrier, M. E., Yang, C. P. H., Yan, H. G., Lopez-Barcons, L., Keller, S. M., Pérez-Soler, R., Horwitz, S. B. & McDaid, H. M., Dec 1 2007, In: Cancer research. 67, 23, p. 11300-11308 9 p.

  Research output: Contribution to journal › Article › peer-review
  79 Scopus citations

• Targeting Rejection: Analysis of Specimen Acceptability and Rejection, and Framework for Identifying Interventions in a Single Tertiary Healthcare Facility

  Rooper, L., Carter, J., Hargrove, J., Hoffmann, S. & Riedel, S., May 2017, In: Journal of Clinical Laboratory Analysis. 31, 3, e22060.

  Research output: Contribution to journal › Article › peer-review
  10 Scopus citations

• Targeting retinoic acid receptor alpha-corepressor interaction activates chaperone-mediated autophagy and protects against retinal degeneration

  Gomez-Sintes, R., Xin, Q., Jimenez-Loygorri, J. I., McCabe, M., Diaz, A., Garner, T. P., Cotto-Rios, X. M., Wu, Y., Dong, S., Reynolds, C. A., Patel, B., de la Villa, P., Macian, F., Boya, P., Gavathiotis, E. & Cuervo, A. M., Dec 2022, In: Nature communications. 13, 1, 4220.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  1 Scopus citations

• Targeting senescence

  Serrano, M. & Barzilai, N., Aug 1 2018, In: Nature Medicine. 24, 8, p. 1092-1094 3 p.

  Research output: Contribution to journal › Article › peer-review
  13 Scopus citations

• Targeting signal transduction pathways in hematopoietic disorders

  Zhou, L. & Verma, A., 2009, Molecular Basis of Hematopoiesis. Springer New York, p. 231-252 22 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter
  1 Scopus citations

• Targeting sleep disruption using sodium oxybate in chronic cluster headache prophylaxis

  Silberstein, S. D. & Robbins, M. S., Jul 5 2011, In: Neurology. 77, 1, p. 16-17 2 p.

  Research output: Contribution to journal › Editorial › peer-review
  3 Scopus citations

• Targeting STING pathways for the treatment of cancer

  Gravekamp, C. & Chandra, D., Dec 2 2015, In: OncoImmunology. 4, 12

  Research output: Contribution to journal › Article › peer-review
  12 Scopus citations

• Targeting survival pathways in lymphoma

  Paoluzzi, L. & O'Connor, O. A., Dec 1 2010, BCL-2 Protein Family: Essential Regulators of Cell Death. Hetz, C. & Hetz, C. (eds.). p. 79-96 18 p. (Advances in Experimental Medicine and Biology; vol. 687).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter
  11 Scopus citations

• Targeting TACE-dependent EGFR ligand shedding in breast cancer

  Kenny, P. A. & Bissell, M. J., Feb 1 2007, In: Journal of Clinical Investigation. 117, 2, p. 337-345 9 p.

  Research output: Contribution to journal › Article › peer-review
  220 Scopus citations

• Targeting the androgen receptor signalling axis in castration-resistant prostate cancer (CRPC)

  Tsao, C. K., Galsky, M. D., Small, A. C., Yee, T. & Oh, W. K., Dec 2012, In: BJU International. 110, 11, p. 1580-1588 9 p.

  Research output: Contribution to journal › Review article › peer-review
  47 Scopus citations

• Targeting the anterior superior iliac spine yields significantly longer bone marrow cores

  Reed, L., Attarian, S., Pendurti, G., Singh, A. P., Budhathoki, A., Abi-Aad, S., Shah, U. A., Kim, S., Bachiashvili, K., Moon, J. Y., Kim, M., Elrafei, T., Alexis, K., Strakhan, M., Li, W. & Friedman, E., Feb 1 2018, In: Journal of Clinical Pathology. 71, 2, p. 172-173 2 p.

  Research output: Contribution to journal › Article › peer-review
  4 Scopus citations

• Targeting the Aryl Hydrocarbon Receptor with Microbial Metabolite Mimics Alleviates Experimental Colitis in Mice

  Grycová, A., Joo, H., Maier, V., Illés, P., Vyhlídalová, B., Poulíková, K., Sládeková, L., Nádvorník, P., Vrzal, R., Zemánková, L., Pečinková, P., Poruba, M., Zapletalová, I., Večeřa, R., Anzenbacher, P., Ehrmann, J., Ondra, P., Jung, J. W., Mani, S. & Dvořák, Z., 2022, (Accepted/In press) In: Journal of Medicinal Chemistry.

  Research output: Contribution to journal › Article › peer-review
  1 Scopus citations

• Targeting the CaMKII/ERK interaction in the heart prevents cardiac hypertrophy

  Cipolletta, E., Rusciano, M. R., Maione, A. S., Santulli, G., Sorriento, D., Del Giudice, C., Ciccarelli, M., Franco, A., Crola, C., Campiglia, P., Sala, M., Gomez-Monterrey, I., De Luca, N., Trimarco, B., Iaccarino, G. & Illario, M., Jun 25 2015, In: PloS one. 10, 6, e0130477.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  44 Scopus citations

• Targeting the chemokines in cardiac repair

  Cavalera, M. & Frangogiannis, N. G., 2014, In: Current pharmaceutical design. 20, 12, p. 1971-1979 9 p.

  Research output: Contribution to journal › Article › peer-review
  46 Scopus citations

• Targeting the chemokines in myocardial inflammation

  Frangogiannis, N. G. & Entman, M. L., Sep 14 2004, In: Circulation. 110, 11, p. 1341-1342 2 p.

  Research output: Contribution to journal › Editorial › peer-review
  29 Scopus citations

• Targeting the glutamatergic system for the treatment of HIV-associated neurocognitive disorders

  Potter, M. C., Figuera-Losada, M., Rojas, C. & Slusher, B. S., Jun 2013, In: Journal of Neuroimmune Pharmacology. 8, 3, p. 594-607 14 p.

  Research output: Contribution to journal › Review article › peer-review
  69 Scopus citations

• Targeting the inflammatory response in healing myocardial infarcts

  Frangogiannis, N. G., Jul 2006, In: Current medicinal chemistry. 13, 16, p. 1877-1893 17 p.

  Research output: Contribution to journal › Review article › peer-review
  170 Scopus citations

• Targeting the MYCN–PARP–DNA damage response pathway in neuroendocrine prostate cancer

  Zhang, W., Liu, B., Wu, W., Li, L., Broom, B. M., Basourakos, S. P., Korentzelos, D., Luan, Y., Wang, J., Yang, G., Park, S., Azad, A. K., Cao, X., Kim, J., Corn, P. G., Logothetis, C. J., Aparicio, A. M., Chinnaiyan, A. M., Navone, N., Troncoso, P., & 1 othersThompson, T. C., Feb 1 2018, In: Clinical Cancer Research. 24, 3, p. 696-707 12 p.

  Research output: Contribution to journal › Article › peer-review
  49 Scopus citations

• Targeting the phenotypic switch of vascular smooth muscle cells to tackle atherosclerosis

  Kansakar, U., Jankauskas, S. S., Gambardella, J. & Santulli, G., May 2021, In: Atherosclerosis. 324, p. 117-120 4 p.

  Research output: Contribution to journal › Editorial › peer-review
  9 Scopus citations

• Targeting the Plasmodium vivax equilibrative nucleoside transporter 1 (PvENT1) for antimalarial drug development

  Deniskin, R., Frame, I. J., Sosa, Y. & Akabas, M. H., Apr 1 2016, In: International Journal for Parasitology: Drugs and Drug Resistance. 6, 1, p. 1-11 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  13 Scopus citations

• Targeting the polyamine pathway with transition-state analogue inhibitors of 5′-methylthioadenosine phosphorylase

  Evans, G. B., Furneaux, R. H., Schramm, V. L., Singh, V. & Tyler, P. C., Jun 3 2004, In: Journal of Medicinal Chemistry. 47, 12, p. 3275-3281 7 p.

  Research output: Contribution to journal › Article › peer-review
  51 Scopus citations

• Targeting the pregnane X receptor using microbial metabolite mimicry

  Dvořák, Z., Kopp, F., Costello, C. M., Kemp, J. S., Li, H., Vrzalová, A., Štěpánková, M., Bartoňková, I., Jiskrová, E., Poulíková, K., Vyhlídalová, B., Nordstroem, L. U., Karunaratne, C. V., Ranhotra, H. S., Mun, K. S., Naren, A. P., Murray, I. A., Perdew, G. H., Brtko, J., Toporova, L., & 22 othersSchön, A., Wallace, W. G., Walton, W. G., Redinbo, M. R., Sun, K., Beck, A., Kortagere, S., Neary, M. C., Chandran, A., Vishveshwara, S., Cavalluzzi, M. M., Lentini, G., Cui, J. Y., Gu, H., March, J. C., Chatterjee, S., Matson, A., Wright, D., Flannigan, K. L., Hirota, S. A., Sartor, R. B. & Mani, S., Apr 7 2020, In: EMBO Molecular Medicine. 12, 4, e11621.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  32 Scopus citations

• Targeting the PXR-TLR4 signaling pathway to reduce intestinal inflammation in an experimental model of necrotizing enterocolitis

  Huang, K., Mukherjee, S., Desmarais, V., Albanese, J. M., Rafti, E., Draghi, A., Maher, L. A., Khanna, K. M., Mani, S. & Matson, A. P., May 1 2018, In: Pediatric Research. 83, 5, p. 1031-1040 10 p.

  Research output: Contribution to journal › Article › peer-review
  30 Scopus citations

• Targeting the safe zone: A quality improvement project to reduce vascular access complications

  Mignatti, A., Friedmann, P. & Slovut, D. P., Jan 1 2018, In: Catheterization and Cardiovascular Interventions. 91, 1, p. 27-32 6 p.

  Research output: Contribution to journal › Article › peer-review
  7 Scopus citations

• Targeting the transforming growth factor (TGF)-β cascade in the remodeling heart: Benefits and perils

  Frangogiannis, N. G., Dec 1 2014, In: Current Therapeutic Research - Clinical and Experimental. 76, p. 169-171 3 p.

  Research output: Contribution to journal › Editorial › peer-review
  21 Scopus citations

• Targeting the tumor microenvironment

  Kenny, P. A., Lee, G. Y. & Bissell, M. J., May 1 2007, In: Frontiers in Bioscience. 12, 9, p. 3468-3474 7 p.

  Research output: Contribution to journal › Review article › peer-review
  163 Scopus citations

• Targeting the untargetable: RB1-deficient tumours are vulnerable to Skp2 ubiquitin ligase inhibition

  Gupta, P., Zhao, H., Hoang, B. & Schwartz, E. L., Oct 5 2022, In: British Journal of Cancer. 127, 6, p. 969-975 7 p.

  Research output: Contribution to journal › Article › peer-review

• Targeting the UPR transcription factor XBP1 protects against Huntington's disease through the regulation of FoxO1 and autophagy

  Vidal, R. L., Figueroa, A., Court, F. A., Thielen, P., Molina, C., Wirth, C., Caballero, B., Kiffin, R., Segura-Aguilar, J., Cuervo, A. M., Glimcher, L. H. & Hetz, C., May 2012, In: Human molecular genetics. 21, 10, p. 2245-2262 18 p., dds040.

  Research output: Contribution to journal › Article › peer-review
  204 Scopus citations

• Targeting the vasculature to improve neural progenitor transplant survival

  Hill, J. & Cave, J., Aug 5 2015, In: Translational Neuroscience. 6, 1, p. 162-167 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  6 Scopus citations