Find Research outputs

Search results

• Targeting angiogenesis in squamous non-small cell lung cancer

  Piperdi, B., Merla, A. & Perez-Soler, R., Mar 2014, In: Drugs. 74, 4, p. 403-413 11 p.

  Research output: Contribution to journal › Review article › peer-review
  52 Scopus citations

• Targeting a novel Plasmodium falciparum purine recycling pathway with specific immucillins

  Ting, L. M., Shi, W., Lewandowicz, A., Singh, V., Mwakingwe, A., Birck, M. R., Taylor Ringia, E. A., Bench, G., Madrid, D. C., Tyler, P. C., Evans, G. B., Furneaux, R. H., Schramm, V. L. & Kim, K., Mar 11 2005, In: Journal of Biological Chemistry. 280, 10, p. 9547-9554 8 p.

  Research output: Contribution to journal › Article › peer-review
  107 Scopus citations

• Targeting a regulator of protein homeostasis in myeloproliferative neoplasms

  Lafave, L. M. & Levine, R. L., Jan 6 2016, In: Nature Medicine. 22, 1, p. 20-21 2 p.

  Research output: Contribution to journal › Comment/debate › peer-review
  4 Scopus citations

• Targeting Bcl-2 family members with the BH3 mimetic AT-101 markedly enhances the therapeutic effects of chemotherapeutic agents in in vitro and in vivo models of B-cell lymphoma

  Paoluzzi, L., Gonen, M., Gardner, J. R., Mastrella, J., Yang, D., Holmlund, J., Sorensen, M., Leopold, L., Manova, K., Marcucci, G., Heaney, M. L. & O'Connor, O. A., Jun 1 2008, In: Blood. 111, 11, p. 5350-5358 9 p.

  Research output: Contribution to journal › Article › peer-review
  135 Scopus citations

• Targeting Behavior of Hepatic Artery Injected Temperature Sensitive Liposomal Adriamycin on Tumor-Bearing Rats

  Zou, Y., Gu, X., Ueno, M., Yamagishi, M., Horikoshi, I., Yamashita, I. & Tazawa, K., Jan 1 1990, In: Selective Cancer Therapeutics. 6, 3, p. 119-127 9 p.

  Research output: Contribution to journal › Article › peer-review
  22 Scopus citations

• Targeting Blood Glucose Management in School Improves Glycemic Control in Children with Poorly Controlled Type 1 Diabetes Mellitus

  Nguyen, T. M., Mason, K. J., Sanders, C. G., Yazdani, P. & Heptulla, R. A., Oct 2008, In: Journal of Pediatrics. 153, 4, p. 575-578 4 p.

  Research output: Contribution to journal › Article › peer-review
  30 Scopus citations

• Targeting CDK1 promotes FLT3-activated acute myeloid leukemia differentiation through C/EBPα

  Radomska, H. S., Alberich-Jordà, M., Will, B., Gonzalez, D., Delwel, R. & Tenen, D. G., Aug 1 2012, In: Journal of Clinical Investigation. 122, 8, p. 2955-2966 12 p.

  Research output: Contribution to journal › Article › peer-review
  42 Scopus citations

• Targeting cell cycle by β-carboline alkaloids in vitro: Novel therapeutic prospects for the treatment of cancer

  Ahmad, I., Fakhri, S., Khan, H., Jeandet, P., Aschner, M. & Yu, Z. L., Oct 1 2020, In: Chemico-Biological Interactions. 330, 109229.

  Research output: Contribution to journal › Review article › peer-review
  16 Scopus citations

• Targeting Chemokine pathways in esophageal adenocarcinoma

  Shrivastava, M. S., Hussain, Z., Giricz, O., Shenoy, N., Polineni, R., Maitra, A. & Verma, A., Nov 1 2014, In: Cell Cycle. 13, 21, p. 3320-3327 8 p.

  Research output: Contribution to journal › Article › peer-review
  24 Scopus citations

• Targeting colon cancer with the novel STAT3 inhibitor bruceantinol

  Wei, N., Li, J., Fang, C., Chang, J., Xirou, V., Syrigos, N. K., Marks, B. J., Chu, E. & Schmitz, J. C., Mar 7 2019, In: Oncogene. 38, 10, p. 1676-1687 12 p.

  Research output: Contribution to journal › Article › peer-review
  36 Scopus citations

• Targeting cyclin D1, a downstream effector of INI1/hSNF5, in rhabdoid tumors

  Alarcon-Vargas, D., Zhang, Z., Agarwal, B., Challagulla, K., Mani, S. & Kalpana, G. V., Feb 2 2006, In: Oncogene. 25, 5, p. 722-734 13 p.

  Research output: Contribution to journal › Article › peer-review
  58 Scopus citations

• Targeting cyclophilin D and the mitochondrial permeability transition enhances β-cell survival and prevents diabetes in Pdx1 deficiency

  Fujimoto, K., Chen, Y., Polonsky, K. S. & Dorn, G. W., Jun 1 2010, In: Proceedings of the National Academy of Sciences of the United States of America. 107, 22, p. 10214-10219 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  65 Scopus citations

• Targeting DDX3 in Medulloblastoma Using the Small Molecule Inhibitor RK-33

  Tantravedi, S., Vesuna, F., Winnard, P. T., Martin, A., Lim, M., Eberhart, C. G., Berlinicke, C., Raabe, E., van Diest, P. J. & Raman, V., Jan 2019, In: Translational Oncology. 12, 1, p. 96-105 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  20 Scopus citations

• Targeting EGFR in HPV-associated cancer

  Sparano, J. A., Haigentz, M. & Einstein, M. H., Dec 1 2010, Molecular Basis for Therapy of AIDS-Defining Cancers. Springer New York, p. 211-234 24 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

• Targeting epigenetic modifications for the treatment and prevention of breast cancer

  Ramaswamy, B. & Sparano, J. A., Dec 1 2010, In: Current Breast Cancer Reports. 2, 4, p. 198-207 10 p.

  Research output: Contribution to journal › Review article › peer-review
  2 Scopus citations

• Targeting ErbB2 aberrations in non-small cell lung cancer

  Ge, X., Tariq, S., Cheng, H. & Halmos, B., Nov 2019, In: Precision Cancer Medicine. 2, November, 27.

  Research output: Contribution to journal › Review article › peer-review

• Targeting estrogens and various estrogen-related receptors against non-small cell lung cancers: A perspective

  Maitra, R., Malik, P. & Mukherjee, T. K., Jan 1 2022, In: Cancers. 14, 1, 80.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  1 Scopus citations

• Targeting family functioning, acculturative stress, and sugar-sweetened beverage consumption for obesity prevention: findings from the Hispanic community children’s health study/study of Latino youth

  Figueroa, R., Isasi, C. R., Perreira, K. M., McClain, A. C., Gallo, L. C., Sotres-Alvarez, D., Delamater, A. M., Daviglus, M., Van Horn, L. & Mattei, J., Dec 1 2020, In: BMC public health. 20, 1, 1546.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  3 Scopus citations

• Targeting Glycoprotein NMB With Antibody-Drug Conjugate, Glembatumumab Vedotin, for the Treatment of Osteosarcoma

  Roth, M., Barris, D. M., Piperdi, S., Kuo, V., Everts, S., Geller, D., Houghton, P., Kolb, E. A., Hawthorne, T., Gill, J. & Gorlick, R., Jan 1 2016, In: Pediatric Blood and Cancer. 63, 1, p. 32-38 7 p.

  Research output: Contribution to journal › Article › peer-review
  42 Scopus citations

• Targeting host cells harbouring viruses with radiolabeled antibodies

  Casadevall, A., Goldstein, H. & Dadachova, E., May 2007, In: Expert opinion on biological therapy. 7, 5, p. 595-597 3 p.

  Research output: Contribution to journal › Short survey › peer-review
  20 Scopus citations

• Targeting HSP90 ameliorates nephropathy and atherosclerosis through suppression of NF-κB and STAT signaling pathways in diabetic mice

  Lazaro, I., Oguiza, A., Recio, C., Mallavia, B., Madrigal-Matute, J., Blanco, J., Egido, J., Martin-Ventura, J. L. & Gomez-Guerrero, C., Oct 2015, In: Diabetes. 64, 10, p. 3600-3613 14 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  42 Scopus citations

• Targeting human papillomavirus type 16 E7 to the endosomal/lysosomal compartment enhances the antitumor immunity of DNA vaccines against murine human papillomavirus type 16 E7-expressing tumors

  Ji, H., Wang, T. L., Chen, C. H., Pai, S. I., Hung, C. F., Lin, K. Y., Kurman, R. J., Pardoll, D. M. & Wu, T. C., Nov 20 1999, In: Human Gene Therapy. 10, 17, p. 2727-2740 14 p.

  Research output: Contribution to journal › Article › peer-review
  213 Scopus citations

• Targeting hypoxic cancer stem cells (CSCs) with Doxycycline: Implications for optimizing anti-angiogenic therapy

  De Francesco, E. M., Maggiolini, M., Tanowitz, H. B., Sotgia, F. & Lisanti, M. P., 2017, In: Oncotarget. 8, 34, p. 56126-56142 17 p.

  Research output: Contribution to journal › Article › peer-review
  35 Scopus citations

• Targeting immunophenotypic markers on leukemic stem cells: How lessons from current approaches and advances in the Leukemia stem cell (LSC) model can inform better strategies for treating acute myeloid leukemia (AML)

  Mitchell, K. & Steidl, U., Jan 2020, In: Cold Spring Harbor Perspectives in Medicine. 10, 1, a036251.

  Research output: Contribution to journal › Article › peer-review
  7 Scopus citations

• Targeting inflammatory pathways in myocardial infarction

  Christia, P. & Frangogiannis, N. G., Sep 2013, In: European Journal of Clinical Investigation. 43, 9, p. 986-995 10 p.

  Research output: Contribution to journal › Review article › peer-review
  150 Scopus citations

• Targeting insulin inhibition as a metabolic therapy in advanced cancer: A pilot safety and feasibility dietary trial in 10 patients

  Fine, E. J., Segal-Isaacson, C. J., Feinman, R. D., Herszkopf, S., Romano, M. C., Tomuta, N., Bontempo, A. F., Negassa, A. & Sparano, J. A., Oct 2012, In: Nutrition. 28, 10, p. 1028-1035 8 p.

  Research output: Contribution to journal › Article › peer-review
  119 Scopus citations

• Targeting invadopodia-mediated breast cancer metastasis by using ABL kinase inhibitors

  Meirson, T., Genna, A., Lukic, N., Makhnii, T., Alter, J., Sharma, V. P., Wang, Y., Samson, A. O., Condeelis, J. S. & Gil-Henn, H., Apr 24 2018, In: Oncotarget. 9, 31, p. 22163-22188 26 p.

  Research output: Contribution to journal › Article › peer-review
  22 Scopus citations

• Targeting liposomes to immune cells

  Levy, M. & Palliser, D., Sep 4 2015, Biomaterials in Regenerative Medicine and the Immune System. Springer International Publishing, p. 193-207 15 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

• Targeting liver tumors by administering liposomal doxorubicin into the hepatic artery

  Zou, Y., Horikoshi, I., Ueno, M., Gu, X. & Perez‐Soler, R., May 8 1992, In: International Journal of Cancer. 51, 2, p. 232-237 6 p.

  Research output: Contribution to journal › Article › peer-review
  11 Scopus citations

• Targeting lung cancer using an infectivity enhanced CXCR4-CRAd

  Zhu, Z. B., Rivera, A. A., Makhija, S. K., Lu, B., Wang, M., Izumi, M., Cerfolio, R. J., Stoff-Khalili, M. A., Zhou, F., Takayama, K., Siegal, G. P. & Curiel, D. T., Feb 2007, In: Lung Cancer. 55, 2, p. 145-156 12 p.

  Research output: Contribution to journal › Article › peer-review
  11 Scopus citations

• Targeting Mac-1-mediated leukocyte–RBC interactions uncouples the benefits for acute vaso-occlusion and chronic organ damage

  Chen, G., Chang, J., Zhang, D., Pinho, S., Jang, J. E. & Frenette, P. S., Oct 1 2016, In: Experimental Hematology. 44, 10, p. 940-946 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  11 Scopus citations

• Targeting mesothelioma using an infectivity enhanced survivin-conditionally replicative adenoviruses

  Zhu, Z. B., Makhija, S. K., Lu, B., Wang, M., Wang, S., Takayama, K., Siegal, G. P., Reynolds, P. N. & Curiel, D. T., Sep 2006, In: Journal of Thoracic Oncology. 1, 7, p. 701-711 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  22 Scopus citations

• Targeting metabotropic glutamate receptors for the treatment of neuroinflammation

  Fazio, F., Ulivieri, M., Volpi, C., Gargaro, M. & Fallarino, F., Feb 2018, In: Current Opinion in Pharmacology. 38, p. 16-23 8 p.

  Research output: Contribution to journal › Review article › peer-review
  22 Scopus citations

• Targeting metabotropic glutamate receptors in neuroimmune communication

  Volpi, C., Fazio, F. & Fallarino, F., Sep 2012, In: Neuropharmacology. 63, 4, p. 501-506 6 p.

  Research output: Contribution to journal › Review article › peer-review
  17 Scopus citations

• Targeting mGlu receptors for optimization of antipsychotic activity and disease-modifying effect in schizophrenia

  Nicoletti, F., Orlando, R., Menna, L. D., Cannella, M., Notartomaso, S., Mascio, G., Iacovelli, L., Matrisciano, F., Fazio, F., Caraci, F., Copani, A., Battaglia, G. & Bruno, V., 2019, In: Frontiers in Psychiatry. 10, FEB, 49.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  20 Scopus citations

• Targeting microtubules for wound repair

  Charafeddine, R. A., Nosanchuk, J. D. & Sharp, D. J., Oct 1 2016, In: Advances in Wound Care. 5, 10, p. 444-454 11 p.

  Research output: Contribution to journal › Review article › peer-review
  8 Scopus citations

• Targeting mitochondrial calcium transport in myocardial infarction

  Frangogiannis, N. G., Jul 1 2018, In: Hellenic Journal of Cardiology. 59, 4, p. 223-225 3 p.

  Research output: Contribution to journal › Editorial › peer-review
  1 Scopus citations

• Targeting mitochondrial structure sensitizes acute myeloid Leukemia to venetoclax treatment

  Chen, X., Glytsou, C., Zhou, H., Narang, S., Reyna, D. E., Lopez, A., Sakellaropoulos, T., Gong, Y., Kloetgen, A., Yap, Y. S., Wang, E., Gavathiotis, E., Tsirigos, A., Tibes, R. & Aifantis, I., Jul 2019, In: Cancer discovery. 9, 7, p. 890-909 20 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  83 Scopus citations

• Targeting mitochondria to oppose the progression of nonalcoholic fatty liver disease

  Grattagliano, I., Montezinho, L. P., Oliveira, P. J., Frühbeck, G., Gómez-Ambrosi, J., Montecucco, F., Carbone, F., Wieckowski, M. R., Wang, D. Q. H. & Portincasa, P., Feb 2019, In: Biochemical Pharmacology. 160, p. 34-45 12 p.

  Research output: Contribution to journal › Review article › peer-review
  27 Scopus citations

• Targeting Mycobacterium tuberculosis tumor necrosis factor alpha-downregulating genes for the development of antituberculous vaccines

  Olsen, A., Chen, Y., Ji, Q., Zhu, G., De Silva, A. D., Vilchèze, C., Weisbrod, T., Li, W., Xu, J., Larsen, M., Zhang, J., Porcelli, S. A., Jacobs, W. R. & Chan, J., 2016, In: mBio. 7, 3, e01023-15.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  23 Scopus citations

• Targeting non-pulmonary vein triggers in persistent atrial fibrillation: Results from a prospective, multicentre, observational registry

  Della Rocca, D. G., Di Biase, L., Mohanty, S., Trivedi, C., Gianni, C., Romero, J., Tarantino, N., Magnocavallo, M., Bassiouny, M., Natale, V. N., Mayedo, A. Q., Macdonald, B., Lavalle, C., Murtaza, G., Akella, K., Forleo, G. B., Al-Ahmad, A., Burkhardt, J. D., Gallinghouse, G. J., Sanchez, J. E. & 4 others, Horton, R. P., Viles-Gonzalez, J. F., Lakkireddy, D. & Natale, A., Dec 1 2021, In: Europace. 23, 12, p. 1939-1949 11 p.

  Research output: Contribution to journal › Article › peer-review
  3 Scopus citations

• Targeting of a conditionally replicative adenovirus agent to human squamous cell carcinomas of the head and neck

  Zhu, Z. B., Mathis, J. M., Makhija, S. K., Lu, B., Wang, M., Ji, S., Rivera, A. A., Rosenthal, E. L., Siegal, G. P. & Curiel, D. T., Nov 2007, In: International journal of oncology. 31, 5, p. 1213-1222 10 p.

  Research output: Contribution to journal › Article › peer-review
  13 Scopus citations

• Targeting of cre to the Foxg1 (BF-1) locus mediates loxP recombination in the telencephalon and other developing head structures

  Hébert, J. M. & McConnell, S. K., Jun 15 2000, In: Developmental Biology. 222, 2, p. 296-306 11 p.

  Research output: Contribution to journal › Article › peer-review
  422 Scopus citations

• Targeting of rough endoplasmic reticulum membrane proteins and ribosomes in invertebrate neurons

  Rolls, M. M., Hall, D. H., Victor, M., Stelzer, E. H. K. & Rapoport, T. A., 2002, In: Molecular biology of the cell. 13, 5, p. 1778-1791 14 p.

  Research output: Contribution to journal › Article › peer-review
  126 Scopus citations

• Targeting of the FYVE domain to endosomal membranes is regulated by a histidine switch

  Lee, S. A., Eyeson, R., Cheever, M. L., Geng, J., Verkhusha, V. V., Burd, C., Overduin, M. & Kutateladze, T. G., Sep 13 2005, In: Proceedings of the National Academy of Sciences of the United States of America. 102, 37, p. 13052-13057 6 p.

  Research output: Contribution to journal › Article › peer-review
  80 Scopus citations

• Targeting of the GTPase Irgm1 to the phagosomal membrane via PtdIns(3,4)P₂ and PtdIns(3,4,5)P₃ promotes immunity to mycobacteria

  Tiwari, S., Choi, H. P., Matsuzawa, T., Pypaert, M. & MacMicking, J. D., 2009, In: Nature Immunology. 10, 8, p. 907-917 11 p.

  Research output: Contribution to journal › Article › peer-review
  94 Scopus citations

• Targeting PBK/TOPK decreases growth and survival of glioma initiating cells in vitro and attenuates tumor growth in vivo

  Joel, M., Mughal, A. A., Grieg, Z., Murrell, W., Palmero, S., Mikkelsen, B., Fjerdingstad, H. B., Sandberg, C. J., Behnan, J., Glover, J. C., Langmoen, I. A. & Stangeland, B., Jun 17 2015, In: Molecular Cancer. 14, 1, 121.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  61 Scopus citations

• Targeting pediatric pedestrian injury prevention efforts: Teasing the information through spatial analysis

  Statter, M., Schuble, T., Harris-Rosado, M., Liu, D. & Quinlan, K., Nov 1 2011, In: Journal of Trauma - Injury, Infection and Critical Care. 71, 5 SUPPL. 2, p. S511-S516

  Research output: Contribution to journal › Article › peer-review
  19 Scopus citations

• Targeting physical activity interventions for adults: When should intervention occur?

  Holliday, K. M., Lin, D. Y., Chakladar, S., Castañeda, S. F., Daviglus, M. L., Evenson, K. R., Marquez, D. X., Qi, Q., Shay, C. M., Sotres-Alvarez, D., Vidot, D. C., Zeng, D. & Avery, C. L., Apr 1 2017, In: Preventive Medicine. 97, p. 13-18 6 p.

  Research output: Contribution to journal › Article › peer-review
  3 Scopus citations

• Targeting plasmodium falciparum purine salvage enzymes: A look at structure-based drug development

  Donaldson, T. & Kim, K., Jan 1 2010, In: Infectious Disorders - Drug Targets. 10, 3, p. 191-199 9 p.

  Research output: Contribution to journal › Article › peer-review
  13 Scopus citations