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Targeted deletion of 5′HS1 and 5′HS4 of the β-globin locus control region reveals additive activity of the DNaseI hypersensitive sites
Bender, M. A., Roach, J. N., Halow, J., Close, J., Alami, R., Bouhassira, E. E., Groudine, M. & Fiering, S. N., Oct 1 2001, In: Blood. 98, 7, p. 2022-2027 6 p.Research output: Contribution to journal › Article › peer-review
65 Scopus citations -
Targeted deletion of AKAP7 in dentate granule cells impairs spatial discrimination
Jones, B. W., Deem, J., Younts, T. J., Weisenhaus, M., Sanford, C. A., Slack, M. C., Chin, J., Nachmanson, D., McKennon, A., Castillo, P. E. & McKnight, G. S., Dec 2 2016, In: eLife. 5, DECEMBER2016, e20695.Research output: Contribution to journal › Article › peer-review
20 Scopus citations -
Targeted deletion of the integrin β4 signaling domain suppresses laminin-5-dependent nuclear entry of mitogen-activated protein kinases and NF-κB, causing defects in epidermal growth and migration
Nikolopoulos, S. N., Blaikie, P., Yoshioka, T., Guo, W., Puri, C., Tacchetti, C. & Giancotti, F. G., Jul 2005, In: Molecular and cellular biology. 25, 14, p. 6090-6102 13 p.Research output: Contribution to journal › Article › peer-review
109 Scopus citations -
Targeted delivery of oligonucleotides into tumor-associated macrophages for cancer immunotherapy
Huang, Z., Zhang, Z., Jiang, Y., Zhang, D., Chen, J., Dong, L. & Zhang, J., Mar 10 2012, In: Journal of Controlled Release. 158, 2, p. 286-292 7 p.Research output: Contribution to journal › Article › peer-review
114 Scopus citations -
Targeted detection and quantitation of histone modifications from 1,000 cells
Abshiru, N. A., Sikora, J. W., Camarillo, J. M., Morris, J. A., Compton, P. D., Lee, T., Neelamraju, Y., Haddox, S., Sheridan, C., Carroll, M., Cripe, L. D., Tallman, M. S., Paietta, E. M., Melnick, A. M., Thomas, P. M., Garrett-Bakelman, F. E. & Kelleher, N. L., Oct 2020, In: PloS one. 15, 10 October, e0240829.Research output: Contribution to journal › Article › peer-review
Open Access -
Targeted disruption of cd39/ATP diphosphohydrolase results in disordered hemostasis and thromboregulation
Enjyoji, K., Sévigny, J., Lin, Y., Frenette, P. S., Christie, P. D., Am Esch, J. S., Imai, M., Edelberg, J. M., Rayburn, H., Lech, M., Beeler, D. L., Csizmadia, E., Wagner, D. D., Robson, S. C. & Rosenberg, R. D., Sep 1999, In: Nature Medicine. 5, 9, p. 1010-1017 8 p.Research output: Contribution to journal › Article › peer-review
465 Scopus citations -
Targeted disruption of the ABP-120 gene leads to cells with altered motility
Cox, D., Condeelis, J., Wessels, D., Soll, D., Kern, H. & Knecht, D. A., 1992, In: Journal of Cell Biology. 116, 4, p. 943-955 13 p.Research output: Contribution to journal › Article › peer-review
Open Access93 Scopus citations -
Targeted disruption of the Kvlqt1 gene causes deafness and gastric hyperplasia in mice
Lee, M. P., Ravenel, J. D., Hu, R. J., Lustig, L. R., Tomaselli, G., Berger, R. D., Brandenburg, S. A., Litzi, T. J., Bunton, T. E., Limb, C., Francis, H., Gorelikow, M., Gu, H., Washington, K., Argani, P., Goldenring, J. R., Coffey, R. J. & Feinberg, A. P., 2000, In: Journal of Clinical Investigation. 106, 12, p. 1447-1455 9 p.Research output: Contribution to journal › Article › peer-review
248 Scopus citations -
Targeted disruption of the mouse colony-stimulating factor 1 receptor gene results in osteopetrosis, mononuclear phagocyte deficiency, increased primitive progenitor cell frequencies, and reproductive defects
Dai, X. M., Ryan, G. R., Hapel, A. J., Dominguez, M. G., Russell, R. G., Kapp, S., Sylvestre, V. & Stanley, E. R., Jan 1 2002, In: Blood. 99, 1, p. 111-120 10 p.Research output: Contribution to journal › Article › peer-review
778 Scopus citations -
Targeted disruption of the murine cholecystokinin-1 receptor promotes intestinal cholesterol absorption and susceptibility to cholesterol cholelithiasis
Wang, D. Q. H., Schmitz, F., Kopin, A. S. & Carey, M. C., Aug 2004, In: Journal of Clinical Investigation. 114, 4, p. 521-528 8 p.Research output: Contribution to journal › Article › peer-review
76 Scopus citations -
Targeted disruption of the murine cholecystokinin-1 receptor promotes intestinal cholesterol absorption and susceptibility to cholesterol cholelithiasis
Wang, D. Q. H., Schmitz, F., Kopin, A. S. & Carey, M. C., Aug 1 2004, In: Journal of Clinical Investigation. 114, 4, p. 521-528 8 p.Research output: Contribution to journal › Article › peer-review
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Targeted disruption of the murine mucin gene 1 decreases susceptibility to cholesterol gallstone formation
Wang, H. H., Afdhal, N. H., Gendler, S. J. & Wang, D. Q. H., Mar 2004, In: Journal of Lipid Research. 45, 3, p. 438-447 10 p.Research output: Contribution to journal › Article › peer-review
36 Scopus citations -
Targeted downregulation of caveolin-1 is sufficient to drive cell transformation and hyperactivate the p42/44 MAP kinase cascade
Galbiati, F., Volonté, D., Engelman, J. A., Watanabe, G., Burk, R., Pestell, R. G. & Lisanti, M. P., Nov 16 1998, In: EMBO Journal. 17, 22, p. 6633-6648 16 p.Research output: Contribution to journal › Article › peer-review
428 Scopus citations -
Targeted expression of an oncogenic adaptor protein v-Crk potentiates axonal growth in dorsal root ganglia and motor neurons in vivo
Weinstein, D. E., Dobrenis, K. & Birge, R. B., Aug 5 1999, In: Developmental Brain Research. 116, 1, p. 29-39 11 p.Research output: Contribution to journal › Article › peer-review
11 Scopus citations -
Targeted GAS6 delivery to the CNS protects axons from damage during experimental autoimmune encephalomyelitis
Gruber, R. C., Ray, A. K., Johndrow, C. T., Guzik, H., Burek, D., De Frutos, P. G. & Shafit-Zagardo, B., Dec 3 2014, In: Journal of Neuroscience. 34, 49, p. 16320-16335 16 p.Research output: Contribution to journal › Article › peer-review
31 Scopus citations -
Targeted gene deletion in Candida parapsilosis demonstrates the role of secreted lipase in virulence
Gácser, A., Trofa, D., Schäfer, W. & Nosanchuk, J. D., Oct 1 2007, In: Journal of Clinical Investigation. 117, 10, p. 3049-3058 10 p.Research output: Contribution to journal › Article › peer-review
106 Scopus citations -
Targeted gene therapy for ovarian cancer
Rocconi, R. P., Numnum, T. M., Stoff-Khalili, M., Makhija, S., Alvarez, R. D. & Curiel, D. T., Dec 1 2005, In: Current Gene Therapy. 5, 6, p. 643-653 11 p.Research output: Contribution to journal › Review article › peer-review
19 Scopus citations -
Targeted inactivation of MLL3 histone H3-Lys-4 methyltransferase activity in the mouse reveals vital roles for MLL3 in adipogenesis
Lee, J., Saha, P. K., Yang, Q. H., Lee, S., Jung, Y. P., Suh, Y., Lee, S. K., Chan, L., Roeder, R. G. & Lee, J. W., Dec 9 2008, In: Proceedings of the National Academy of Sciences of the United States of America. 105, 49, p. 19229-19234 6 p.Research output: Contribution to journal › Article › peer-review
Open Access136 Scopus citations -
Targeted inactivation of p27kip1 is sufficient for large and small intestinal tumorigenesis in the mouse, which can be augmented by a Western-style high-risk diet
Yang, W. C., Bancroft, L., Nicholas, C., Lozonschi, I. & Augenlicht, L. H., Aug 15 2003, In: Cancer research. 63, 16, p. 4990-4996 7 p.Research output: Contribution to journal › Article › peer-review
50 Scopus citations -
Targeted inactivation of the p21WAF1/cip1gene enhances Apc-initiated tumor formation and the tumor-promoting activity of a Western-style high-risk diet by altering cell maturation in the intestinal mucosa
Wan Cai, Y. C., Mathew, J., Velcich, A., Edelmann, W., Kucherlapati, R., Lipkin, M., Yang, K. & Augenlicht, L. H., Jan 15 2001, In: Cancer research. 61, 2, p. 565-569 5 p.Research output: Contribution to journal › Article › peer-review
144 Scopus citations -
Targeted inhibition of farnesyltransferase in locally advanced breast cancer: A phase I and II trial of tipifarnib plus dose-dense doxorubicin and cyclophosphamide
Sparano, J. A., Moulder, S., Kazi, A., Vahdat, L., Li, T., Pellegrino, C., Munster, P., Malafa, M., Lee, D., Hoschander, S., Hopkins, U., Hershman, D., Wright, J. J. & Sebti, S. M., Jul 1 2006, In: Journal of Clinical Oncology. 24, 19, p. 3013-3018 6 p.Research output: Contribution to journal › Article › peer-review
47 Scopus citations -
Targeted inhibition of the E3 ligase SCFSkp2/Cks1 has antitumor activity in RB1-deficient human and mouse small-cell lung cancer
Zhao, H., Iqbal, N. J., Sukrithan, V., Nicholas, C., Xue, Y., Yu, C., Locker, J., Zou, J., Schwartz, E. L. & Zhu, L., Jun 2020, In: Cancer research. 80, 11, p. 2355-2367 13 p.Research output: Contribution to journal › Article › peer-review
4 Scopus citations -
Targeted killing of virally infected cells by radiolabeled antibodies to viral proteins
Dadachova, E., Patel, M. C., Toussi, S., Apostolidis, C., Morgenstern, A., Brechbiel, M. W., Gorny, M. K., Zolla-Pazner, S., Casadevall, A. & Goldstein, H., Nov 2006, In: PLoS Medicine. 3, 11, p. 2094-2103 10 p.Research output: Contribution to journal › Article › peer-review
69 Scopus citations -
Targeted loss of ghr signaling in mouse skeletal muscle protects against high-fat diet-induced metabolic deterioration
Vijayakumar, A., Wu, Y. J., Sun, H., Li, X., Jeddy, Z., Liu, C., Schwartz, G. J., Yakar, S. & LeRoith, D., Jan 2012, In: Diabetes. 61, 1, p. 94-103 10 p.Research output: Contribution to journal › Article › peer-review
Open Access57 Scopus citations -
Targeted metabolic labeling of yeast N-glycans with unnatural sugars
Breidenbach, M. A., Gallagher, J. E. G., King, D. S., Smart, B. P., Wu, P. & Bertozzi, C. R., Mar 2 2010, In: Proceedings of the National Academy of Sciences of the United States of America. 107, 9, p. 3988-3993 6 p.Research output: Contribution to journal › Article › peer-review
Open Access62 Scopus citations -
Targeted Metabolomic Analysis of Serum Fatty Acids for the Prediction of Autoimmune Diseases
Tsoukalas, D., Fragoulakis, V., Sarandi, E., Docea, A. O., Papakonstaninou, E., Tsilimidos, G., Anamaterou, C., Fragkiadaki, P., Aschner, M., Tsatsakis, A., Drakoulis, N. & Calina, D., Nov 1 2019, In: Frontiers in Molecular Biosciences. 6, 120.Research output: Contribution to journal › Article › peer-review
Open Access39 Scopus citations -
Targeted molecular therapy of anaplastic thyroid carcinoma with AEE788
Kim, S., Schiff, B. A., Yigitbasi, O. G., Doan, D., Jasser, S. A., Bekele, B. N., Mandal, M. & Myers, J. N., Apr 2005, In: Molecular cancer therapeutics. 4, 4, p. 632-640 9 p.Research output: Contribution to journal › Article › peer-review
44 Scopus citations -
Targeted Mutation of the MLN64 START Domain Causes only Modest Alterations in Cellular Sterol Metabolism
Kishida, T., Kostetskii, I., Zhang, Z., Martinez, F., Liu, P., Walkley, S. U., Dwyer, N. K., Blanchette-Mackie, E. J., Radice, G. L. & Strauss, J. F., Apr 30 2004, In: Journal of Biological Chemistry. 279, 18, p. 19276-19285 10 p.Research output: Contribution to journal › Article › peer-review
Open Access74 Scopus citations -
Targeted Next-Generation Sequencing in Molecular Subtyping of Lower-Grade Diffuse Gliomas: Application of the World Health Organization's 2016 Revised Criteria for Central Nervous System Tumors
Carter, J. H., McNulty, S. N., Cimino, P. J., Cottrell, C. E., Heusel, J. W., Vigh-Conrad, K. A. & Duncavage, E. J., Mar 1 2017, In: Journal of Molecular Diagnostics. 19, 2, p. 328-337 10 p.Research output: Contribution to journal › Article › peer-review
21 Scopus citations -
Targeted overexpression of endothelial nitric oxide synthase in endothelial cells improves cerebrovascular reactivity in Ins2 Akita-type-1 diabetic mice
Chandra, S. B., Mohan, S., Ford, B. M., Huang, L., Janardhanan, P., Deo, K. S., Cong, L., Muir, E. R. & Duong, T. Q., Jun 1 2016, In: Journal of Cerebral Blood Flow and Metabolism. 36, 6, p. 1135-1142 8 p.Research output: Contribution to journal › Article › peer-review
Open Access12 Scopus citations -
Targeted radionuclide therapies for pancreatic cancer
Shah, M., Da Silva, R., Gravekamp, C., Libutti, S. K., Abraham, T. & Dadachova, E., Aug 18 2015, In: Cancer gene therapy. 22, 8, p. 375-379 5 p.Research output: Contribution to journal › Article › peer-review
17 Scopus citations -
Targeted Radionuclide Therapy of Melanoma
Norain, A. & Dadachova, E., May 1 2016, In: Seminars in nuclear medicine. 46, 3, p. 250-259 10 p.Research output: Contribution to journal › Review article › peer-review
26 Scopus citations -
Targeted removal of bioavailable metal as a detoxification strategy for carbon nanotubes
Liu, X., Guo, L., Morris, D., Kane, A. & Hurt, R., 2008, 8th World Biomaterials Congress 2008. p. 1730 1 p. (8th World Biomaterials Congress 2008; vol. 3).Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
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Targeted removal of bioavailable metal as a detoxification strategy for carbon nanotubes
Liu, X., Guo, L., Morris, D., Kane, A. B. & Hurt, R. H., Mar 2008, In: Carbon. 46, 3, p. 489-500 12 p.Research output: Contribution to journal › Article › peer-review
122 Scopus citations -
Targeted RNA editing: novel tools to study post-transcriptional regulation
Xu, W., Biswas, J., Singer, R. H. & Rosbash, M., Jan 20 2022, In: Molecular Cell. 82, 2, p. 389-403 15 p.Research output: Contribution to journal › Review article › peer-review
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Targeted sequencing to discover germline variants in the BRCA1 and BRCA2 genes in a Russian population and their association with breast cancer risk
Solodskikh, S. A., Panevina, A. V., Gryaznova, M. V., Gureev, A. P., Serzhantova, O. V., Mikhailov, A. A., Maslov, A. Y. & Popov, V. N., Jan 2019, In: Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. 813, p. 51-57 7 p.Research output: Contribution to journal › Article › peer-review
5 Scopus citations -
Targeted short read sequencing and assembly of re-arrangements and candidate gene loci provide megabase diplotypes
Shin, G. W., Greer, S. U., Xia, L. C., Lee, H. J., Zhou, J., Boles, T. C. & Ji, H. P., Nov 4 2019, In: Nucleic acids research. 47, 19, p. e115Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Targeted short-term fluconazole prophylaxis among very low birth weight and extremely low birth weight infants
Uko, S., Soghier, L. M., Vega, M., Marsh, J., Reinersman, G. T., Herring, L., Dave, V. A., Nafday, S. & Brion, L. P., 2006, In: Pediatrics. 117, 4, p. 1243-1252 10 p.Research output: Contribution to journal › Article › peer-review
94 Scopus citations -
Targeted Spontaneous Reporting: Assessing Opportunities to Conduct Routine Pharmacovigilance for Antiretroviral Treatment on an International Scale
Rachlis, B., Karwa, R., Chema, C., Pastakia, S., Olsson, S., Wools-Kaloustian, K., Jakait, B., Maina, M., Yotebieng, M., Kumarasamy, N., Freeman, A., de Rekeneire, N., Duda, S. N., Davies, M. A. & Braitstein, P., Oct 1 2016, In: Drug Safety. 39, 10, p. 959-976 18 p.Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations -
Targeted surgical therapy for lung cancer
Stiles, B. M., Nov 1 2018, In: Journal of Thoracic Disease. 10, p. S3904-S3907Research output: Contribution to journal › Review article › peer-review
Open Access2 Scopus citations -
Targeted temperature management for cardiac arrest
Moskowitz, A., Berg, K. M. & Donnino, M. W., Jun 25 2020, In: New England Journal of Medicine. 382, 26, 2011066.Research output: Contribution to journal › Letter › peer-review
1 Scopus citations -
Targeted therapies of the LKB1/AMPK pathway for the treatment of insulin resistance
Yamada, E., Lee, T. W. A., Pessin, J. E. & Bastie, C. C., Dec 2010, In: Future Medicinal Chemistry. 2, 12, p. 1785-1796 12 p.Research output: Contribution to journal › Review article › peer-review
15 Scopus citations -
Targeted therapy
Chu, E., Jan 2007, In: Clinical colorectal cancer. 6, 5, p. 336 1 p.Research output: Contribution to journal › Editorial › peer-review
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Targeted Therapy for Hepatocellular Carcinoma
Ohri, N., Kaubisch, A., Garg, M. & Guha, C., Oct 1 2016, In: Seminars in Radiation Oncology. 26, 4, p. 338-343 6 p.Research output: Contribution to journal › Review article › peer-review
18 Scopus citations -
Targeted Therapy in Biliary Tract Cancers
Merla, A., Liu, K. G. & Rajdev, L., Oct 17 2015, In: Current treatment options in oncology. 16, 10, 48.Research output: Contribution to journal › Review article › peer-review
25 Scopus citations -
Targeted therapy of osteosarcoma with radiolabeled monoclonal antibody to an insulin-like growth factor-2 receptor (IGF2R)
Geller, D. S., Morris, J., Revskaya, E., Kahn, M., Zhang, W., Piperdi, S., Park, A., Koirala, P., Guzik, H., Hall, C., Hoang, B., Yang, R., Roth, M., Gill, J., Gorlick, R. & Dadachova, E., Dec 1 2016, In: Nuclear Medicine and Biology. 43, 12, p. 812-817 6 p.Research output: Contribution to journal › Article › peer-review
18 Scopus citations -
Targeted treatments for symptom domains in child and adolescent autism
Hollander, E., Phillips, A. T. & Yeh, C. C., Aug 30 2003, In: Lancet. 362, 9385, p. 732-734 3 p.Research output: Contribution to journal › Short survey › peer-review
65 Scopus citations -
Targeting AID to the Ig genes
Li, Z., Luo, Z., Ronai, D., Li Kuang, F., Peled, J. U., Iglesias-Ussel, M. D. & Scharff, M. D., 2007, Mechanisms of Lymphocyte Activation and Immune Regulation XI: B Cell Biology. Springer New York, p. 93-109 17 p. (Advances in Experimental Medicine and Biology; vol. 596).Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
4 Scopus citations -
Targeting AID to the Ig genes.
Li, Z., Luo, Z., Ronai, D., Kuang, F. L., Peled, J. U., Iglesias-Ussel, M. D. & Scharff, M. D., 2007, In: Advances in Experimental Medicine and Biology. 596, p. 93-109 17 p.Research output: Contribution to journal › Article › peer-review
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Targeting angiogenesis in gastrointestinal tumors: Current challenges
Nandikolla, A. G. & Rajdev, L., 2016, In: Translational Gastroenterology and Hepatology. 2016, SEP, 67.Research output: Contribution to journal › Review article › peer-review
11 Scopus citations