Find Research Outputs

2019
1 Citation (Scopus)

Human Tumor-Associated Macrophage and Monocyte Transcriptional Landscapes Reveal Cancer-Specific Reprogramming, Biomarkers, and Therapeutic Targets

Cassetta, L., Fragkogianni, S., Sims, A. H., Swierczak, A., Forrester, L. M., Zhang, H., Soong, D. Y. H., Cotechini, T., Anur, P., Lin, E. Y., Fidanza, A., Lopez-Yrigoyen, M., Millar, M. R., Urman, A., Ai, Z., Spellman, P. T., Hwang, E. S., Dixon, J. M., Wiechmann, L., Coussens, L. M. & 2 othersSmith, H. O. & Pollard, J. W., Apr 15 2019, In : Cancer Cell. 35, 4, p. 588-602.e10

Research output: Contribution to journalArticle

Open Access
Monocytes
Biomarkers
Macrophages
Breast Neoplasms
Transcriptome
T-Cell Antigen Receptor
Urinary Bladder Neoplasms
T-Lymphocytes
Tumor-Infiltrating Lymphocytes
Urinary Bladder

Hyperglycemia-induced oxidative brain injury: Therapeutic effects of Cola nitida infusion against redox imbalance, cerebellar neuronal insults, and upregulated Nrf2 expression in type 2 diabetic rats

Erukainure, O. L., Ijomone, O. M., Oyebode, O. A., Chukwuma, C. I., Aschner, M. & Islam, M. S., May 1 2019, In : Food and Chemical Toxicology. 127, p. 206-217 12 p.

Research output: Contribution to journalArticle

Therapeutic Uses
hyperglycemia
Medical problems
Hyperglycemia
Brain Injuries

Identification of chimeric RNAs in human infant brains and their implications in neural differentiation

Tang, Y., Ma, S., Wang, X., Xing, Q., Huang, T., Liu, H., Li, Q., Zhang, Y., Zhang, K., Yao, M., Yang, G. L., Li, H., Zang, X., Yang, B. & Guan, F., Jun 1 2019, In : International Journal of Biochemistry and Cell Biology. 111, p. 19-26 8 p.

Research output: Contribution to journalArticle

Brain
RNA
Physiology
Stem cells
Tissue

Identifying and reengaging patients lost to follow-up in rural Africa: The “horizontal” hospital-based approach in Uganda

Alizadeh, F., Mfitumuhoza, G., Stephens, J., Habimaana, C., Myles, K., Baganizi, M. & Paccione, Jr., G. A., Mar 1 2019, In : Global Health Science and Practice. 7, 1, p. 103-115 13 p.

Research output: Contribution to journalArticle

Open Access
Uganda
Lost to Follow-Up
Chronic Disease
Motorcycles
Rural Hospitals
Open Access
Adult T Cell Leukemia Lymphoma
Population
mogamulizumab
1 Citation (Scopus)

IFITM3 directly engages and shuttles incoming virus particles to lysosomes

Spence, J. S., He, R., Hoffmann, H. H., Das, T., Thinon, E., Rice, C. M., Peng, T., Chandran, K. & Hang, H. C., Jan 1 2019, (Accepted/In press) In : Nature Chemical Biology.

Research output: Contribution to journalArticle

Lysosomes
Virion
Lipoylation
Transport Vesicles
Virus Diseases

If You See Something, Say Something

Kitsis, E. A. & Fleischman, A. R., Jan 1 2019, In : JAMA Neurology.

Research output: Contribution to journalComment/debate

1 Citation (Scopus)

IGF-1 Deficiency Promotes Pathological Remodeling of Cerebral Arteries: A Potential Mechanism Contributing to the Pathogenesis of Intracerebral Hemorrhages in Aging

Fulop, G. A., Ramirez-Perez, F. I., Kiss, T., Tarantini, S., Valcarcel Ares, M. N., Toth, P., Yabluchanskiy, A., Conley, S. M., Ballabh, P., Martinez-Lemus, L. A., Ungvari, Z. & Csiszar, A., Mar 14 2019, In : Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 74, 4, p. 446-454 9 p.

Research output: Contribution to journalArticle

Open Access
Cerebral Arteries
Cerebral Hemorrhage
Somatomedins
Middle Cerebral Artery
Extracellular Matrix

Illicit substance use after release from prison among formerly incarcerated primary care patients: a cross-sectional study

Chamberlain, A., Nyamu, S., Aminawung, J., Wang, E. A., Shavit, S. & Fox, A. D., Feb 19 2019, In : Addiction science & clinical practice. 14, 1, 1 p.

Research output: Contribution to journalArticle

Prisons
Primary Health Care
Cross-Sectional Studies
Substance-Related Disorders
Alcohols
Urinary Bladder Neoplasms
Canidae
Gene Ontology
Urinary Bladder
Carcinoma

Immune Checkpoint Blockade Is Associated With Durable Responses in Pulmonary Sarcomatoid Carcinoma

Sukrithan, V., Sandler, J., Gucalp, R. A., Gralla, R. J. & Halmos, B., Jan 1 2019, (Accepted/In press) In : Clinical Lung Cancer.

Research output: Contribution to journalArticle

Tumor Burden
Immunotherapy
Carcinoma
Lung
pembrolizumab
1 Citation (Scopus)

Immune Response and Intraocular Inflammation in Patients with Leber Hereditary Optic Neuropathy Treated with Intravitreal Injection of Recombinant Adeno-Associated Virus 2 Carrying the ND4 Gene: A Secondary Analysis of a Phase 1/2 Clinical Trial

Bouquet, C., Vignal Clermont, C., Galy, A., Fitoussi, S., Blouin, L., Munk, M. R., Valero, S., Meunier, S., Katz, B., Sahel, J. A. & Thomasson, N., Jan 1 2019, In : JAMA Ophthalmology.

Research output: Contribution to journalArticle

Leber's Hereditary Optic Atrophy
Dependovirus
Clinical Trials, Phase I
Intravitreal Injections
Inflammation
Dysbiosis
Immune Tolerance
Premature Birth
High Fat Diet
Gene Expression

Immunization of Vγ2Vδ2 T cells programs sustained effector memory responses that control tuberculosis in nonhuman primates

Shen, L., Frencher, J., Huang, D., Wang, W., Yang, E., Chen, C. Y., Zhang, Z., Wang, R., Qaqish, A., Larsen, M. H., Shen, H., Porcelli, S. A., Jacobs, W. R. & Chen, Z. W., Jan 1 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 13, p. 6371-6378 8 p.

Research output: Contribution to journalArticle

Open Access
Primates
Immunization
Tuberculosis
T-Lymphocytes
Tuberculosis Vaccines

Immunomodulatory Effects of Stereotactic Body Radiation Therapy: Preclinical Insights and Clinical Opportunities

Marciscano, A. E., Haimovitz-Friedman, A., Lee, P., Tran, P. T., Tome, W. A., Guha, C., (Spring) Kong, F. M., Sahgal, A., El Naqa, I., Rimner, A., Marks, L. B., Formenti, S. C. & DeWeese, T. L., Jan 1 2019, In : International Journal of Radiation Oncology Biology Physics.

Research output: Contribution to journalArticle

radiation therapy
Radiotherapy
Left ventricular assist devices
Heart-Assist Devices
Blood pressure
Blood Pressure
Pressure
2 Citations (Scopus)

Impact of afatinib dose modification on safety and effectiveness in patients with EGFR mutation-positive advanced NSCLC: Results from a global real-world study (RealGiDo)

Halmos, B., Tan, E. H., Soo, R. A., Cadranel, J., Lee, M. K., Foucher, P., Hsia, T. C., Hochmair, M., Griesinger, F., Hida, T., Kim, E., Melosky, B., Märten, A. & Carcereny, E., Jan 1 2019, In : Lung Cancer. 127, p. 103-111 9 p.

Research output: Contribution to journalArticle

Safety
Mutation
Lung
Treatment Failure
Incidence
Prescription Drugs
Drug Monitoring
Opioid Analgesics
Prescriptions
Insurance

Impact of dense “smoke” detected on transesophageal echocardiography on stroke risk in patients with atrial fibrillation undergoing catheter ablation

Gedikli, Ö., Mohanty, S., Trivedi, C., Gianni, C., Chen, Q., Della Rocca, D. G., Burkhardt, J. D., Sanchez, J. E., Hranitzky, P., Gallinghouse, G. J., Al-Ahmad, A., Horton, R., Di Biase, L. & Natale, A., Jan 1 2019, (Accepted/In press) In : Heart Rhythm.

Research output: Contribution to journalArticle

Catheter Ablation
Transesophageal Echocardiography
Smoke
Atrial Fibrillation
Transient Ischemic Attack

Impact of hepatitis C treatment on pain intensity, prescription opioid use and arthritis

Kumthekar, A. A., Shull, S., Lovejoy, T. I., Morasco, B. J., Chang, M. & Barton, J., Jan 1 2019, In : International Journal of Rheumatic Diseases.

Research output: Contribution to journalArticle

Hepatitis C
Opioid Analgesics
Arthritis
Prescriptions
Pain
1 Citation (Scopus)

Impact of human papillomavirus vaccination on the clinical meaning of cervical screening results

Castle, P. E., Xie, X., Xue, X. N., Poitras, N. E., Lorey, T. S., Kinney, W. K., Wentzensen, N., Strickler, H., Burger, E. A. & Schiffman, M., Jan 1 2019, In : Preventive Medicine. 118, p. 44-50 7 p.

Research output: Contribution to journalArticle

Vaccination
Cell Biology
Human papillomavirus 18
Cervical Intraepithelial Neoplasia
Human papillomavirus 16
Vulnerable Populations
Primary Care Physicians
Lung Neoplasms
Primary Health Care
Mortality

Impact of reproductive aging on the vaginal microbiome and soluble immune mediators in women living with and at-risk for HIV infection

Murphy, K. J., Keller, M. J., Anastos, K., Sinclair, S., Cooper Devlin, J., Shi, Q., Hoover, D. R., Starkman, B., McGillick, J., Mullis, C., Minkoff, H., Dominguez-Bello, M. G. & Herold, B., Apr 1 2019, In : PLoS ONE. 14, 4, e0216049.

Research output: Contribution to journalArticle

Open Access
Microbiota
HIV infections
Atopobium vaginae
Lactobacillus
Escherichia coli
6 Citations (Scopus)

Impact of scaled up human papillomavirus vaccination and cervical screening and the potential for global elimination of cervical cancer in 181 countries, 2020–99: a modelling study

Simms, K. T., Steinberg, J., Caruana, M., Smith, M. A., Lew, J. B., Soerjomataram, I., Castle, P. E., Bray, F. & Canfell, K., Mar 1 2019, In : The Lancet Oncology. 20, 3, p. 394-407 14 p.

Research output: Contribution to journalArticle

Human Development
Uterine Cervical Neoplasms
Vaccination
Incidence
Neoplasms

Improving adolescent access and services in a large primary care network: Report of a 10 year project

Alderman, E. M., Freeman, K. L. & Lobach, K. S., Jan 1 2019, In : International Journal of Adolescent Medicine and Health. 31, 2, 0163.

Research output: Contribution to journalArticle

Primary Health Care
Adolescent Health Services
Adolescent Medicine
Attitude of Health Personnel
Delivery of Health Care
Hospitalized Adolescent
Preventive Medicine
Chlamydia
Gonorrhea
Electronic Health Records

Incidence and Predictors of Hardware Failure After Instrumentation for Spine Metastasis: A Single-Institutional Series

Longo, M., De la Garza Ramos, R., Gelfand, Y., Echt, M., Kinon, M. D. & Yassari, R., Jan 1 2019, In : World Neurosurgery.

Research output: Contribution to journalArticle

Multiple Myeloma
Spine
Neoplasm Metastasis
Incidence
Logistic Models

Incidental discovery of tracheal bronchus during lung isolation for transthoracic esophagectomy

Rosenberg, J. W., Lee, K. H. & Leff, J. D., Mar 1 2019, In : Journal of Clinical Anesthesia. 53, p. 77-78 2 p.

Research output: Contribution to journalLetter

Incidental Findings
Esophagectomy
Bronchi
Lung

Increasing Diversity in Clinical Trials: Overcoming Critical Barriers

Clark, L. T., Watkins, L., Pina, I. L., Elmer, M., Akinboboye, O., Gorham, M., Jamerson, B., McCullough, C., Pierre, C., Polis, A. B., Puckrein, G. & Regnante, J. M., May 1 2019, In : Current Problems in Cardiology. 44, 5, p. 148-172 25 p.

Research output: Contribution to journalReview article

Open Access
Clinical Trials
Physicians
Safety
Intrinsic Factor
Life Style

Increasing the dose intensity of chemotherapy by more frequent administration or sequential scheduling: a patient-level meta-analysis of 37 298 women with early breast cancer in 26 randomised trials

Early Breast Cancer Trialists' Collaborative Group (EBCTCG), Apr 6 2019, In : The Lancet. 393, 10179, p. 1440-1452 13 p.

Research output: Contribution to journalArticle

Open Access
Meta-Analysis
Breast Neoplasms
Drug Therapy
Appointments and Schedules
Recurrence
2 Citations (Scopus)

Inhibition of ATP citrate lyase (ACLY) protects airway epithelia from PM2.5-induced epithelial-mesenchymal transition

Fu, Y., Lu, R., Cui, J., Sun, H., Yang, H., Meng, Q., Wu, S., Aschner, M., Li, X. & Chen, R., Jan 15 2019, In : Ecotoxicology and Environmental Safety. 167, p. 309-316 8 p.

Research output: Contribution to journalArticle

ATP Citrate (pro-S)-Lyase
Enzyme inhibition
Epithelial-Mesenchymal Transition
Adenosinetriphosphate
Epithelium

Inhibition of polarity-regulating kinase PAR1b contributes to Helicobacter pylori inflicted DNA Double Strand Breaks in gastric cells

Zamperone, A., Cohen, D., Stein, M., Viard, C. & Muesch, A., Jan 1 2019, (Accepted/In press) In : Cell Cycle.

Research output: Contribution to journalArticle

Double-Stranded DNA Breaks
Helicobacter pylori
Stomach
Phosphotransferases
Helicobacter Infections

Inhibitors of energy metabolism interfere with antibiotic-induced death in mycobacteria

Lee, B. S., Kalia, N. P., Jin, X. E. F., Hasenoehrl, E. J., Berney, M. & Pethe, K., Jan 1 2019, In : Journal of Biological Chemistry. 294, 6, p. 1936-1943 8 p.

Research output: Contribution to journalArticle

Mycobacterium
Energy Metabolism
Anti-Bacterial Agents
Proton-Translocating ATPases
Isoniazid

Insights from deconvolution of cell subtype proportions enhance the interpretation of functional genomic data

Kong, Y., Rastogi, D., Seoighe, C., Greally, J. M. & Suzuki, M., Apr 1 2019, In : PLoS ONE. 14, 4, e0215987.

Research output: Contribution to journalArticle

Open Access
Deconvolution
genomics
Blood
Tissue
cells

Integration of Onsite Long-Acting Reversible Contraception Services Into School-Based Health Centers

Summit, A. K., Friedman, E., Stein, T. B. & Gold, M., Mar 1 2019, In : Journal of School Health. 89, 3, p. 226-231 6 p.

Research output: Contribution to journalArticle

School Health Services
contraception
Contraception
Contraceptive Agents
contraceptive

Integrative resident education curriculum to adapt to the modern otolaryngology trainee

Moskowitz, H. S. & Hsueh, W. D., Jan 1 2019, In : Laryngoscope.

Research output: Contribution to journalArticle

Otolaryngology
Curriculum
Education
Educational Measurement
Laryngoscopes

Intensive Glucose Control for Critically Ill Patients

Conway, J. & Friedman, B. W., Jan 1 2019, In : Academic Emergency Medicine.

Research output: Contribution to journalArticle

Hepatitis C
Opioid Analgesics
Randomized Controlled Trials
Pharmaceutical Preparations
Directly Observed Therapy

Interdisciplinary Relationship Models for Complementary and Integrative Health: Perspectives of Chinese Medicine Practitioners in the United States

Anderson, B. J., Jurawanichkul, S., Kligler, B. E., Marantz, P. R. & Evans, R., Mar 1 2019, In : Journal of Alternative and Complementary Medicine. 25, 3, p. 288-295 8 p.

Research output: Contribution to journalArticle

Cultural Diversity
Medicine
Health
Patient Care
Integrative Medicine

Interneurons: Learning on the Job

Batista-Brito, R. A. & Fishell, G., Jun 5 2019, In : Neuron. 102, 5, p. 905-907 3 p.

Research output: Contribution to journalShort survey

Pyramidal Cells
Interneurons
Learning
Gene Expression

Interrogating the genetic determinants of Tourette's syndrome and other tiC disorders through genome-wide association studies

Tourette Association of America International Consortium for Genetics, Gilles de la Tourette GWAS Replication Initiative, Tourette International Collaborative Genetics Study & Psychiatric Genomics Consortium Tourette Syndrome Working Group, Jan 1 2019, In : American Journal of Psychiatry. 176, 3, p. 217-227 11 p.

Research output: Contribution to journalArticle

Tic Disorders
Tourette Syndrome
Genome-Wide Association Study
Tics
Meta-Analysis

Intestinal Spirochetosis Resembles Inflammatory Bowel Disease in a Patient With HIV Infection

Agrawal, M., Zhang, W. & Lukin, D. J., Jan 1 2019, (Accepted/In press) In : Clinical Gastroenterology and Hepatology.

Research output: Contribution to journalArticle

Inflammatory Bowel Diseases
HIV Infections
Open Access
Thoracic Aorta

Intramyocardial Injection of Mesenchymal Precursor Cells and Successful Temporary Weaning from Left Ventricular Assist Device Support in Patients with Advanced Heart Failure: A Randomized Clinical Trial

Yau, T. M., Pagani, F. D., Mancini, D. M., Chang, H. L., Lala, A., Woo, Y. J., Acker, M. A., Selzman, C. H., Soltesz, E. G., Kern, J. A., Maltais, S., Charbonneau, E., Pan, S., Marks, M. E., Moquete, E. G., O'Sullivan, K. L., Taddei-Peters, W. C., McGowan, L. K., Green, C., Rose, E. A. & 10 othersJeffries, N., Parides, M. K., Weisel, R. D., Miller, M. A., Hung, J., O'Gara, P. T., Moskowitz, A. J., Gelijns, A. C., Bagiella, E. & Milano, C. A., Mar 26 2019, In : JAMA - Journal of the American Medical Association. 321, 12, p. 1176-1186 11 p.

Research output: Contribution to journalArticle

Heart-Assist Devices
Weaning
Randomized Controlled Trials
Heart Failure
Injections

Intrinsic tumor necrosis factor-α pathway is activated in a subset of patients with focal segmental glomerulosclerosis

Chung, C. F., Kitzler, T., Kachurina, N., Pessina, K., Babayeva, S., Bitzan, M., Kaskel, F. J., Colmegna, I., Alachkar, N., Goodyer, P., Cybulsky, A. V. & Torban, E., May 1 2019, In : PloS one. 14, 5, e0216426.

Research output: Contribution to journalArticle

Open Access
Focal Segmental Glomerulosclerosis
tumor necrosis factors
nephrotic syndrome
Podocytes
Poisons
Connexins
Nervous System Diseases

In vivo photoacoustic multi-contrast imaging and detection of protein interactions using a small near-infrared photochromic protein

Li, L., Shemetov, A., Hu, P., Shcherbakova, D., Shi, J., Yao, J., Verkhusha, V. & Wang, L. V., Jan 1 2019, Photons Plus Ultrasound: Imaging and Sensing 2019. Oraevsky, A. A. & Wang, L. V. (eds.). SPIE, 1087818. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; vol. 10878).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Photoacoustic effect
Tomography
Pulse code modulation
tomography
Infrared radiation