3H-1,2-dithiole-3-thione protects PC12 cells against amyloid beta 1–42 (Aβ_1–42) induced apoptosis via activation of the ERK1/2 pathway

Medicine & Life Sciences

• 1,2-dithiol-3-thione 93%
• PC12 Cells 58%
• MAP Kinase Signaling System 56%
• Amyloid 48%
• Apoptosis 31%
• L-Lactate Dehydrogenase 21%
• Phosphatidylinositol 3-Kinases 14%
• Reactive Oxygen Species 11%
• Cell Survival 11%
• Fluo-3 10%
• diacetyldichlorofluorescein 10%
• bcl-2-Associated X Protein 9%
• 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one 8%
• 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one 8%
• Pheochromocytoma 8%
• Neuroprotective Agents 7%
• Protein Kinases 6%
• Caspase 3 6%
• Alzheimer Disease 5%
• Flow Cytometry 5%
• Calcium 4%
• Western Blotting 4%
• Proteins 2%

Chemical Compounds

• 3H-1,2-dithiole-3-thione 100%
• Beta-Amyloid 57%
• Lactate 38%
• Cell Viability 25%
• Reactive Oxygen Metabolite 23%
• LY294002 23%
• Fluo-3 21%
• Pathway Inhibitor 21%
• Neuroprotective 16%
• Protein 15%
• Cytometry 13%
• Protective 10%
• Calcium(0) 9%
• Flow 8%