2,8-dihydroxyadenine urolithiasis

report of a case first diagnosed after renal transplant.

D. Glicklich, H. E. Gruber, A. J. Matas, V. A. Tellis, G. Karwa, K. Finley, C. Salem, R. Soberman, J. E. Seegmiller

Research output: Contribution to journalArticle

37 Citations (Scopus)

Abstract

We report a case of homozygous adenine phosphoribosyl transferase (APRT) deficiency associated with 2,8-dihydroxyadenine stones recurrent in a patient with a renal transplant. The disease was diagnosed 23 years after the initial episode of renal colic. At that time the disease was unknown. Our patient is only the second case of this disorder reported from the United States. Correct diagnosis is important because long-term maintenance with allopurinol and a low purine diet can effectively prevent stone formation and renal failure.

Original languageEnglish (US)
Pages (from-to)785-793
Number of pages9
JournalThe Quarterly journal of medicine
Volume68
Issue number258
StatePublished - Oct 1988

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Renal Colic
Transplants
Kidney
Allopurinol
Adenine
Transferases
Renal Insufficiency
Diet
Adenine phosphoribosyltransferase deficiency
2,8-dihydroxyadenine
purine

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Glicklich, D., Gruber, H. E., Matas, A. J., Tellis, V. A., Karwa, G., Finley, K., ... Seegmiller, J. E. (1988). 2,8-dihydroxyadenine urolithiasis: report of a case first diagnosed after renal transplant. The Quarterly journal of medicine, 68(258), 785-793.

2,8-dihydroxyadenine urolithiasis : report of a case first diagnosed after renal transplant. / Glicklich, D.; Gruber, H. E.; Matas, A. J.; Tellis, V. A.; Karwa, G.; Finley, K.; Salem, C.; Soberman, R.; Seegmiller, J. E.

In: The Quarterly journal of medicine, Vol. 68, No. 258, 10.1988, p. 785-793.

Research output: Contribution to journalArticle

Glicklich, D, Gruber, HE, Matas, AJ, Tellis, VA, Karwa, G, Finley, K, Salem, C, Soberman, R & Seegmiller, JE 1988, '2,8-dihydroxyadenine urolithiasis: report of a case first diagnosed after renal transplant.', The Quarterly journal of medicine, vol. 68, no. 258, pp. 785-793.
Glicklich D, Gruber HE, Matas AJ, Tellis VA, Karwa G, Finley K et al. 2,8-dihydroxyadenine urolithiasis: report of a case first diagnosed after renal transplant. The Quarterly journal of medicine. 1988 Oct;68(258):785-793.
Glicklich, D. ; Gruber, H. E. ; Matas, A. J. ; Tellis, V. A. ; Karwa, G. ; Finley, K. ; Salem, C. ; Soberman, R. ; Seegmiller, J. E. / 2,8-dihydroxyadenine urolithiasis : report of a case first diagnosed after renal transplant. In: The Quarterly journal of medicine. 1988 ; Vol. 68, No. 258. pp. 785-793.
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