2-oxo-3-alkynoic acids, universal mechanism-based inactivators of thiamin diphosphate-dependent decarboxylases: Synthesis and evidence for potent inactivation of the pyruvate dehydrogenase multienzyme complex

Angela Brown, Natalia Nemeria, Jizu Yi, Deqi Zhang, William B. Jordan, Rosane S. Machado, John R. Guest, Frank Jordan

Research output: Contribution to journalArticlepeer-review

18 Scopus citations

Fingerprint

Dive into the research topics of '2-oxo-3-alkynoic acids, universal mechanism-based inactivators of thiamin diphosphate-dependent decarboxylases: Synthesis and evidence for potent inactivation of the pyruvate dehydrogenase multienzyme complex'. Together they form a unique fingerprint.

Medicine & Life Sciences

Chemical Compounds