Prometheus: A Platform for Rapid Development of Human Antibody-based Therapeutics and Prophylactics against Emerging Viral Threats

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• Finished

  Core A: Administrative Core

  Chandran, K. & Chandran, K.

  National Institute of Allergy and Infectious Diseases

  3/1/19 → 1/31/24

  Project: Research project

  • Hantavirus 100%
  • Intellectual Property 72%
  • Nairovirus 42%
  • Sin Nombre virus 40%
  • Zoonoses 25%

• Project I: Discovery and Evaluation of Antibodies and Cocktails

  Chandran, K. & Chandran, K.

  National Institute of Allergy and Infectious Diseases

  3/1/19 → 1/31/24

  Project: Research project

  • Hantavirus 100%
  • Monoclonal Antibodies 85%
  • Sin Nombre virus 80%
  • Viruses 63%
  • Antibodies 57%

• In Vivo Efficacy Testing Core

  Chandran, K. & Chandran, K.

  National Institute of Allergy and Infectious Diseases

  3/1/19 → 1/31/24

  Project: Research project

  • Hantavirus 100%
  • Nairovirus 67%
  • Lead 64%
  • Ebolavirus 63%
  • Rodent Diseases 62%

• Core B: Industrialization Core

  Chandran, K. & Chandran, K.

  National Institute of Allergy and Infectious Diseases

  3/1/19 → 1/31/24

  Project: Research project

  • Industrial Development 100%
  • Monoclonal Antibodies 34%
  • Survivors 27%
  • Technology 20%
  • Glycosylation 16%

• Project II: Biologics Engineering and Antibody Mechanism of Action

  Chandran, K. & Chandran, K.

  National Institute of Allergy and Infectious Diseases

  3/1/19 → 1/31/24

  Project: Research project

  • Biological Products 100%
  • Medical Countermeasures 78%
  • Ebolavirus 65%
  • Monoclonal Antibodies 59%
  • Antibodies 54%