• Pessin, Jeffrey E. (PI)
  • Feldman, Ross (PI)
  • Turek, Lubomir (PI)
  • Donelson, John (PI)
  • Walder, Joseph (PI)
  • Feldbush, Thomas (PI)
  • Spaziani, Eugene (PI)
  • Ginsberg, Barry (PI)
  • Sigmund, Curt Daniel (PI)
  • Bar, Robert (PI)
  • Sandra, Alexander (PI)
  • Yorek, Mark Anthony (PI)
  • Moser, David (PI)
  • Sivitz, William (PI)
  • Bar, Robert (PI)
  • Sandra, Alexander (PI)
  • Yorek, Mark Anthony (PI)
  • Moser, David (PI)
  • Sivitz, William (PI)
  • Pessin, Jeffrey E. (PI)

Project: Research project

Project Details


The Iowa Diabetes-Endocrinology Research CEnter (DERC) is
designed to foster a multidisciplinary approach to the study of
hormone action at the cellular and molecular level.
Investigations primarily relate to the effects of insulin and
insulin-like growth factors, gene regulation, and steroid hormone
action, however, also included are studies of the action of
catecholamines, prolactin and gonadotrophin releasing hormone.

The center has 5 major goals: (1) to promote multidisciplinary
approaches to the study of mechanisms of hormone action
through collaborative studies; (2) to develop molecular biology
approaches to hormone action; (3) to test new hypotheses related
to mechanisms of hormone action through the Pilot and
Feasibility Programs; (4) to centralize facilities that were being
duplicated in several different laboratories; (5) to provide, as
core resources, facilities and expertise that are not available at
the University but would be advantageous to multiple DERC

To achieve these goals, the Center has developed several
resource cores: An Administration Core; Computer Core; Cell
Biology Core (Media Production and Monoclonal Antibody
Production); Membrane Biology Core (Central Facility for
Peptide Iodination, Membrane Preparation and Analysis, and
Receptor Localization); Molecular Biology Core (Recombinant
DNA and DNA Synthesis); an Enrichment Program of seminar
speakers and workshops and a Pilot and Feasibility Study
Program to support pilot studies related to the center theme.
Effective start/end date1/1/0111/30/02


  • Genetics
  • Endocrinology
  • Molecular Biology
  • Immunology
  • Biochemistry
  • Endocrinology, Diabetes and Metabolism
  • Cell Biology
  • Aquatic Science
  • Animal Science and Zoology
  • Computer Science(all)
  • Neuroscience(all)
  • Artificial Intelligence
  • Chemical Engineering(all)
  • Medicine(all)
  • Biochemistry, Genetics and Molecular Biology(all)
  • Pathology and Forensic Medicine
  • Filtration and Separation
  • Computer Graphics and Computer-Aided Design


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