Mouse Models of Human Conotruncal Defects

Project: Research project

Project Details

Description

We will determine the molecular pathogenesis of CTDs by taking mouse genetics approaches. We propose that Tbxl genetic pathways are required for cardiac outflow tract development and when altered alters risk to CTDs in 22q11DS (Project 1) and more frequent non-syndromic forms (Project 2).
StatusFinished
Effective start/end date9/24/116/30/16

Funding

  • National Institute of Child Health and Human Development: $281,762.00
  • National Institute of Child Health and Human Development: $359,287.00
  • National Institute of Child Health and Human Development: $261,178.00
  • National Institute of Child Health and Human Development: $271,357.00
  • National Institute of Child Health and Human Development: $275,255.00

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