Project Details
Description
Project Narrative
In the United States, about 12,000 premature infants develop bleeding in and around the
ventricle (cavity) of the brain each year, which results in neuropsychiatric complications
in the survivors including mental retardation, attention deficit, hyperactivity, major
depressive episodes, and epilepsy. These disorders are attributed to abnormal
development and function of interneurons in the brain. Brain bleeds in premature infants
might suppress the generation and maturation of interneurons. In this proposal, we will
determine whether the brain hemorrhage affects the formation of interneurons and test
strategies to restore the development of interneurons and organization of brain layers in
our preterm rabbit model of brain hemorrhage.
Status | Active |
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Effective start/end date | 3/15/19 → 2/28/23 |
Funding
- National Institute of Neurological Disorders and Stroke: $328,781.00
- National Institute of Neurological Disorders and Stroke: $349,758.00
- National Institute of Neurological Disorders and Stroke: $365,313.00
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