Human Gut Microbiome and Incident Diabetes Risk in U.S. Populations

Project: Research project

Project Details

Description

Project Narrative/Relevance New technology that allows the classification of thousands of gut microbial features has made it possible to identify the many physiological and metabolic processes through which microbiota may influence the health of their hosts. Evidence from animal experiments and feeding studies has suggested that microbiota may modulate the risk of diabetes, although few prospective studies have been conducted to establish the relationship between gut microbiome and diabetes incidence. This study aims to examine microbiota composition, functional potential, and fecal metabolome in relation to the risk of developing diabetes in two well-established cohorts of U.S. men and women with complementary ethnic and socioeconomic backgrounds. Study findings will help identify novel microbial features as targets for developing individualized prevention and intervention strategies to alleviate the increasing societal and healthcare burden of diabetes.
StatusActive
Effective start/end date1/19/2112/31/22

Funding

  • National Institute of Diabetes and Digestive and Kidney Diseases: $669,600.00
  • National Institute of Diabetes and Digestive and Kidney Diseases: $547,270.00

Fingerprint

Explore the research topics touched on by this project. These labels are generated based on the underlying awards/grants. Together they form a unique fingerprint.